Typing tool
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Typing tool
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Complete norovirus genomes
| AB933691 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 1..5097
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933691 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Miyazaki5/2010/JP genomic RNA, complete genome.
ACCESSION AB933691
VERSION AB933691.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Miyazaki5/2010/JP
ORGANISM Norovirus Hu/GII.4/Miyazaki5/2010/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Miyazaki5/2010/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Miyazaki5/2010/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498685"
/geo_loc_name="Japan:Miyazaki"
/collection_date="2010"
CDS 1..5097
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30133.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDKMLSSMAVTFKRALGARP
KQPPPREIPQGPPRPTTPELVKKIPPPPPNGEDEVVVSYSAKDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSALFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALVTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNTSIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEETTNKDGC
PKPKDNEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVAIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPVIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30134.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRDVPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30135.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAVLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARATTYNAGRFSTPQPSGALPGRANPRTPTPARSSPSTSS
NTSAATSIHSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHVRRRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacaa aatgctttct agcatggctg tcactttcaa acgagccctc
121 ggggcgcggc ctaaacagcc ccccccgagg gaaataccac aaggaccccc acgaccaact
181 actccagaac tggtcaaaaa gatccctccc cccccgccca acggagagga tgaagtagtg
241 gtttcttata gtgccaaaga tggtgtttcc ggtttgcctg agctttccac cgtcaggcaa
301 ccggaagaaa ccaatacggc tttcagtgtc cctcccctca atcagaggga gaatagggat
361 gctaaggaac cactgactgg aacaattctg gaaatgtggg atggggaaat ctaccattat
421 ggcctgtatg ttgagcgagg tcttgtgctg ggtgtgcaca aaccaccagc tgccattagc
481 ctcgccaagg tcgaactaac accactctcc ttgttctgga gacctgtgta cactcctcag
541 tacctcatct ctccagacac tctcaagaaa ttacacggag aaacatttcc ctacacagcc
601 ttcgacaaca attgctatgc cttctgttgc tgggtcctgg atctaaacga ctcgtggctg
661 agtaggagaa tgatccagag aacaactggc ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagctaacat attcctgtgc
781 accctgtctg cgctattcac cagacccata aaagacataa tagggaagtt aaggcctctc
841 aacatcatca atatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
901 atactcttgg cagagctctt tggagtcttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggtgattt cgagttacaa gggcctgagg accttgtagt ggagctcgtc
1021 cctgtagtaa tggggggaat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc taccttaaga gcttgtaaag atcttggtgc gtatgggcta
1141 gagatcctaa agttagtcat gaagtggttc ttcccgaaga aagaggaagc aaatgaactg
1201 gctatggtga gatccatcga ggatgcagtg ctagaccttg aggcaattga aaacaaccat
1261 atgaccacct tgctcaaaga caaagacagc ctggcaacct atatgagaac ccttgacctc
1321 gaggaagaga aagccagaaa actctcaacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgccc ttctggcgag aatcgccgct gcacgctccc tggtgcaccg agcgaaggag
1441 gagctttcta gcagaccaag acctgtagtc ttgatgatat caggcagacc aggaataggg
1501 aagacccacc ttgctaggga agtggctaag aggatcgcag cctccctcac aggagaccag
1561 cgtgtaggcc tcatcccacg caatggcgtc gatcactggg atgcgtacaa gggggagagg
1621 gtcgtcctat gggacgacta tggaatgagc aatcccatcc acgacgccct caggctgcaa
1681 gaactcgctg acacttgccc cctcactcta aactgtgaca ggattgagaa taaaggaaag
1741 gtctttgaca gcgatgtcat catcatcact actaacctgg ccaacccagc accactggac
1801 tatgtcaact ttgaagcgtg ctcgaggcgc attgatttcc tcgtgtatgc agaagccccc
1861 gaggtcgaaa aggcgaagcg tgacttcccg ggccaacctg acatgtggaa aaacgctttt
1921 agtcctgatt tctcacatat aaagttggca ctggctccac aaggtggctt tgataagaac
1981 gggaacaccc cacatgggaa gggcgtcatg aagactctca ccactggctc cctcattgcc
2041 agggcatcag ggctgctcca tgagagattg gatgagtttg aactacaggg cccagctctt
2101 gtcaccttca actttgatcg caacaaagtg cttgccttca ggcagcttgc tgctgaaaat
2161 aagtacgggc tgatggacac aatgaaagtt gggaggcagc tcaaggatgt caaaaccatg
2221 ccagaactta aacaagcact caagaatacc tcaatcaaga agtgccagat tgtgtatagt
2281 ggttgcacct acacacttga gtctgatggc aagggcaatg tgaaagttga cagagttcag
2341 agcacctccg ttcagaccaa caatgagctg gctggcgccc tgcaccacct gaggtgcgcc
2401 agaatcaggt actatgtcaa gtgtgttcag gaggccctgt attctatcat ccagattgct
2461 ggggctgcat ttgtcaccac gcgcatcatc aagcgcgtga acattcaaga cttatggtcc
2521 aagccacaag tggaaaacac agaggagacc accaacaagg acgggtgccc aaaacccaaa
2581 gataatgagg agttcgtcat ttcatctgac gacattaaaa ctgagggtaa gaaagggaag
2641 aacaagactg gccgtggcaa gaagcacaca gccttctcaa gtaaaggtct cagtgatgaa
2701 gagtatgatg agtacaagag aattagagag gaaaggaatg gtaagtactc catagaagag
2761 tatcttcagg acagggacaa atactatgag gaggtggcca ttgccagggc gaccgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tcttcagacc aacaaggaaa
2881 caacgcaagg aagaaagagc ttctctcggt ttagtcacag gttctgaaat taggaaaagg
2941 aacccagacg acttcaagcc taaggggaaa ctatgggctg acgatgacag aagcgtggac
3001 tacaatgaaa aactcagttt tgaggcccca ccaagcatct ggtcaaggat agtcaacttt
3061 ggctcaggtt ggggcttctg ggtctccccc agcctgttta taacatcaac ccacgtcata
3121 ccccaaggcg cgaaggagtt ctttggagtc cccatcaaac aaattcaggt acacaagtca
3181 ggcgaattct gtcgcttgag gttcccaaaa ccaatcagga ctgatgtgac tggcatgatc
3241 ttggaagaag gtgcgcccga aggcaccgtg gccacactac tcatcaaaag gtctactgga
3301 gaactcatgc ccttagcagc tagaatgggg acccatgcaa ccatgaaaat tcaagggcgc
3361 actgttggag gtcagatggg catgcttctg acaggatcca acgccaaaag catggatcta
3421 ggcaccacac caggtgattg cggctgtccc tacatctaca agagaggaaa tgactatgtg
3481 gccattggag tccacacggc tgccgctcgt gggggaaaca ctgtcatatg tgccacccag
3541 gggagtgagg gggaagctac acttgaaggt ggtgacagta agggaacata ctgtggcgca
3601 ccaattctag gcccagggag tgccccaaaa cttagcacca aaaccaaatt ctggagatca
3661 tccacagcac cactcccacc tggcacctat gaaccagcct accttggtgg caaggacccc
3721 agagtcaagg gtggcccctc gttacagcaa gttatgaggg accagttgaa gccatttaca
3781 gagcctaggg gtaagccacc aaagccaagt gtgttagaag ctgccaagaa aaccatcata
3841 aatgtccttg aacaaacaat tgacccacct gagaagtggt cgttcgcaca agcttgcgcg
3901 tcccttgaca agaccacttc tagcggccat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggaat ctttcacagg caagctggcg gaccaggctt ccaaggccaa cctgatgttt
4021 gaagaaggga agaacatgac cccagtctac acaggtgcac ttaaggatga attagtcaaa
4081 actgacaaaa tttatggtaa gatcaagaag aggcttctct ggggctcgga tttggcaacc
4141 atgatccggt gtgctcgagc attcggaggc ctaatggatg aactcaaagc acactgtgtc
4201 acactcccta tcagagttgg tatgaatatg aatgaggatg gccccgtcat cttcgagaag
4261 cattccaggt acagatacca ctatgatgct gattactctc ggtgggattc aacacaacag
4321 agagccgtgc tggcagctgc tctagaaatc atggttaaat tctcctcaga accgcatttg
4381 gctcaggtag tagcagaaga ccttctttct cctagcgtgg tggacgtggg tgacttcaca
4441 atatcaatca acgagggtct tccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcactct ctgtgcactc tccgaagtta caaatttgtc cccagacatc
4561 atacaggcta attctctctt ctccttctat ggtgacgatg aaattgttag tacggacata
4621 aaattagacc cagagaagtt gacagcaaag cttaaggaat acgggttgaa accaacccgc
4681 cctgataaaa ctgaaggacc tcttgttatt tctgaagact tagatggctt gaccttccta
4741 cggagaactg tgacccgcga cccagctggt tggtttggaa aattggagca gagctcaata
4801 ctcaggcaaa tgtactggac taggggccct aaccatgaag atccatctga atcaatgatt
4861 ccacactctc aaagacccat acaattgatg tccttactgg gagaggccgc actccacggc
4921 ccaacattct acagtaaaat cagcaaatta gtcattgcag agttaaaaga aggtggcatg
4981 gatttttacg tgcccaggca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtctaatga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgtcg gtgccgctat tgcggcgcct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtgtc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcaccc ttaggccctg atctgaatcc
5341 ctacctatct catttggcca gaatgtataa tggttacgca ggtggttttg aagtgcaggt
5401 gatcctcgcg gggaacgcgt tcaccgccgg aaaaattata tttgcagcag tcccaccaaa
5461 ttttccaact gaaggcttga gtcccagcca ggtcactatg ttcccccaca taatagtgga
5521 tgttaggcaa ttggaacctg tgttgatccc cttacctgat gttaggaata acttctatca
5581 ttataatcaa tcaaatgatt ctaccattaa attgatagca atgctgtata caccacttag
5641 ggctaataat gctggggaag atgtcttcac agtctcttgt cgagtcctca cgaggccatc
5701 ccctgatttt gattttatat ttttggtgcc acctacagtt gagtcaagaa ctaaaccatt
5761 cactgtccca atcttaactg ttgaggaaat gaccaattca agattcccca ttcctttgga
5821 aaagttgttc acgggtccta gcagtgcctt tgttgtccaa ccacaaaatg gcagatgcac
5881 gactgatggc gtgctcttag gcaccaccca actgtctcct gtcaacatct gcaccttcag
5941 aggggatgtc acccacattg caggttctcg taattacaca atgaatttgg cttctctaaa
6001 ctggaacaat tatgacccaa cagaagaaat tccagcccct ctaggaactc cggatttcgt
6061 gggaaagatc caaggtatgc tcactcaaac cacaaaagga gatggttcga cccgtggcca
6121 taaagccaca gtttacactg ggagtgcccc ctttactcca aagctgggca gtgttcaatt
6181 cagtactgat acagaaaatg attttgaaac ccaccaaaac acaaaattca ccccagtcgg
6241 tgtcatccag gatggtagca ccacccaccg aaatgaaccc caacaatggg tgctcccaag
6301 ttattcaggt agagatgtcc ctaatgtaca cctagcccct gctgtagctc ccactttccc
6361 gggtgaacaa ctccttttct ttaggtctac tatgcccgga tgcagcgggt atcccaacat
6421 ggatttggat tgcctactcc cccaggagtg ggttcagcac ttctaccaag aggcagctcc
6481 agcacaatct gatgtggctc tattgagatt tgtgaatcca gacacgggta gggtcctgtt
6541 tgagtgcaaa cttcataaat caggctatgt cacagtggct cacaccggcc agcatgattt
6601 ggtcatcccc cccaatggtt attttaggtt tgattcctgg gttaatcaat tctacacact
6661 tgcccccatg ggaaatggaa cggggcgtag acgtgcttta taatggctgg agctttcttt
6721 gctggattgg catctgatgt ccttagctct ggacttggtt ccctaatcaa tgctggggct
6781 ggggctatca accaaaagat tgattttgaa aataacagaa aattgcagca agcttccttc
6841 cagtttagca gtaatctaca acaggcttct tttcaacatg ataaagaaat gctccaagca
6901 caaattgagg ccactaaaaa gttgcaacag gaaatgatga aagttaaaca ggcagtgctc
6961 ttagaaggtg gattctctga aacagatgca gcccgtgggg caatcaacgc ccctatgaca
7021 aaggctttgg actggagcgg aacaaggtac tgggcccctg atgctagggc tacaacatac
7081 aacgcaggcc gcttttccac ccctcaacct tcgggggcac tgccaggaag agccaatccc
7141 agaactccta cccccgctcg gagctccccc agcacatctt ctaatacttc tgctgcaact
7201 tctatacatt caaatcaaac tgtttcaacg agacttggtt ctacagctgg ttctggcacc
7261 agtgtctcga gtctcccgtc aactgcaagg accaggagtt gggttgagga ccaaaacaga
7321 aatttgtcac ctttcatgag gggggctcac aacatatcgt ttgtcacccc accatctagc
7381 agatcctcta gccaaggcac agtctcaacc gtgcctaaag aagttttgga ctcctggact
7441 ggcgctttca acacgcgcag gcagcctctc ttcgctcacg ttcgtaggcg aggggagtca
7501 cgggtgtaa
//