Typing tool
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Typing tool
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Complete norovirus genomes
| AB933685 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 1..5097
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933685 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Ehime3/2010/JP genomic RNA, complete genome.
ACCESSION AB933685
VERSION AB933685.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Ehime3/2010/JP
ORGANISM Norovirus Hu/GII.4/Ehime3/2010/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Ehime3/2010/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Ehime3/2010/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498679"
/country="Japan:Ehime"
/collection_date="2010"
CDS 1..5097
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30115.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDKMFSSMAVTFKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDEVVVSYSAKDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
FAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEAANEDGC
PKPKDNEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVAGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKDGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVMDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30116.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRDYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVRFSTDTENDFEIHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRDAHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30117.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGAPPGRTNPRTPTPARGSPSTSS
NASTATSIYSNQTVSTRLGSTAGSGTNISSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacaa aatgttttct agcatggctg tcacttttaa acgagccctc
121 ggggcgcggc ctaaacagcc ccccccgagg gagataccac aaagaccccc acgaccacct
181 actccagaac tggtcaaaaa gatccctcct cccccgccca acggagagga tgaagtagtg
241 gtttcttata gtgccaaaga tggcgtttcc ggtttgcctg agctttccac tgtcaggcag
301 ccggaagaaa ccaatacggc cttcagtgtc cctccactca atcagaggga gaacagggat
361 gctaaggaac cactgactgg aacaattctg gaaatgtggg atggagaaat ttaccattat
421 ggcctgtatg ttgagcgagg tcttgtgctg ggtgtgcaca aaccaccagc tgccattagc
481 ttcgccaagg tcgaactaac accactctcc ttgttctgga gacctgtgta cactcctcag
541 tacctcatct ctccagacac tctcaagaaa ttacacggag aaacatttcc ctacacagcc
601 ttcgacaaca attgctatgc cttttgttgc tgggtcctgg acctaaacga ctcgtggctg
661 agtaggagaa tgatccagag aacaactggt ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tagctaacat attcctgtgc
781 accctgtctt cgctattcac caggcccata aaagacataa tagggaagtt aaggcctctc
841 aacatcatca acatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
901 atactcttgg cagagctctt tggagtcttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggtgattt cgagttacaa ggacctgagg accttgtagt ggagctcgtc
1021 cctgtagtaa tggggggaat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc taccttgaga gcttgtaaag atcttggtgc atatgggcta
1141 gagatcctaa agttagtcat gaagtggttc ttcccgaaga aagaggaagc aaatgaactg
1201 gctatggtga gatccatcga ggatgcagta ctggaccttg aggcaattga aaacaatcat
1261 atgaccacct tgctcaaaga caaagacagc ctggcaacct atatgagaac ccttgacctc
1321 gaggaagaga aagccagaaa actctcaacc aagtctgctt cacctgacat cgtgggcaca
1381 attaacgccc ttctggcgag aattgccgct gcacgctccc tggtgcaccg agcgaaggag
1441 gagctttcca gcagaccaag acctgtagtc ttgatgatat caggcagacc aggaataggg
1501 aagacccacc ttgctaggga agtggctaag aaaatcgcag cctccctcac aggagaccag
1561 cgtgtaggcc tcatcccacg caatggcgtc gatcactggg atgcgtacaa gggggagagg
1621 gttgtcctat gggacgacta tggaatgagt aatcccatcc acgacgccct caggctgcaa
1681 gaacttgctg acacttgccc cctcactcta aattgtgaca ggattgagaa taaaggaaag
1741 gtctttgaca gcgatgtcat cattatcact actaacttgg ctaacccagc accactggac
1801 tatgtcaact ttgaagcatg ctcgaggcgc atcgacttcc tcgtgtatgc agaagccccc
1861 gaggtcgaaa aggcgaagcg tgacttcccg ggccaacctg acatgtggaa aaacgctttt
1921 agtcctgatt tctcacacat aaaattggca ctggctccac aaggtggctt tgataagaac
1981 gggaacaccc cacacgggaa gggcgtcatg aagactctca ccactggctc cctcattgcc
2041 cgggcatcag ggctgctcca tgagagattg gatgagtttg aactacaggg cccagctctt
2101 accaccttca actttgaccg caacaaagtg cttgccttca gacagcttgc tgctgaaaac
2161 aaatacgggt tgatggatac aatgaaagtt gggaggcagc tcaaggatgt caaaaccatg
2221 ccagaactta aacaagcact caagaatatc tcaatcaaga agtgccagat tgtgtatagt
2281 ggttgcacct acacacttga gtctgatggc aagggcaatg tgaaagttga cagagttcag
2341 agcacctccg ttcagaccaa caatgagctg gctggcgccc tgcaccatct aaggtgcgcc
2401 agaatcaggt actatgtcaa gtgtgttcag gaggccctgt attctatcat ccaaattgct
2461 ggggctgcat ttgtcaccac gcgcatcatc aagcgtgtga acattcagga cttgtggtcc
2521 aagccacaag tggaaaacac agaggaggct gccaacgagg acgggtgccc aaagcccaaa
2581 gataatgagg agttcgtcat ttcatctgac gacattaaaa ctgagggtaa gaaagggaag
2641 aacaagactg gccgtggcaa gaagcacaca gccttctcaa gtaaaggtct cagtgatgaa
2701 gagtatgatg agtacaagag aattagagag gagaggaatg gcaagtactc catagaagag
2761 taccttcagg acagggacaa atactatgag gaggtggcca ttgccagggc gaccgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tcttcagacc aacaaggaaa
2881 caacgcaagg aagaaagggc ttctctcggt ttagtcacag gttctgaaat taggaaaagg
2941 aacccagaag acttcaagcc taaggggaaa ctatgggctg acgatgacag aagtgtggac
3001 tacaatgaaa aactcagctt tgaggcccca ccaagcatct ggtcaaggat agtcaacttt
3061 ggctcaggtt ggggcttctg ggtctccccc agcctgttca taacatcaac ccacgtcata
3121 ccccagggcg caaaggagtt ctttggagtc cccatcaaac aaattcaggt acacaagtca
3181 ggcgaattct gtcgcttgag gttcccaaaa ccaatcagga ctgatgtggc tggcatgatc
3241 ttggaagaag gtgcgcccga aggcaccgtg gtcacactac tcatcaaaag gtctactgga
3301 gaactcatgc ccctagcagc tagaatgggg acccatgcaa ccatgaaaat tcaaggacgc
3361 actgttggag gccagatggg catgcttctg acaggatcca acgccaaaag catggaccta
3421 ggcaccacac caggtgattg cggctgtccc tacatttaca agagagggaa tgactatgtg
3481 gtcattgggg tccacacggc tgccgctcgt gggggaaaca ctgtcatatg tgccacccag
3541 gggggtgagg gggaagctac acttgaaggt ggtgacagta agggaacata ctgtggtgca
3601 ccaatcctag gcccagggag tgccccaaaa cttagcacca aaaccaaatt ctggagatca
3661 tccacagcac cactcccacc tggcacctat gaaccagcct accttggtgg caaggacccc
3721 agagtcaagg atggcccctc tctgcagcaa gtcatgaggg accagctgaa accatttaca
3781 gaacctaggg gtaagccacc aaagccaagc gtgttggaag ctgccaagaa aaccatcatc
3841 aatgtccttg aacaaacaat tgacccacct gagaagtggt cgttcgcaca agcttgcgcg
3901 tcccttgaca agaccacttc tagcggccat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggaat ccttcacagg caagctggca gaccaggctt ccaaggccaa cttgatgttt
4021 gaagaaggga agaacatgac cccagtctac acaggtgcac ttaaggatga gttagtcaaa
4081 actgacaaaa tttatggtaa gatcaagaag aggcttctct ggggctcgga tttggcaacc
4141 atgatccggt gtgctcgagc attcggaggt ctaatggatg aactcaaagc acactgtgtc
4201 acacttccta tcagagttgg tatgaatatg aatgaggatg gccccatcat cttcgagaag
4261 cattccaggt acagatacca ctatgatgct gattactctc ggtgggattc aacacaacag
4321 agagccgtgc tggcagctgc tctagaaatc atggttaaat tctcctcaga accacacttg
4381 gcccaggtgg tagcagaaga ccttctttct cctagcgtga tggatgtggg tgacttcaca
4441 atatcaatca acgagggtct tccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcactct ctgtgcactc tccgaagtta caaatttgtc cccagacatc
4561 atacaggcta actctctctt ctccttctat ggtgatgatg aaattgttag tacagacata
4621 aaattagacc cagagaagtt gacagcaaag cttaaggaat acgggttgaa accaacccgc
4681 cctgacaaaa ctgaaggacc tcttgttatc tctgaagact tggatggttt gactttcctg
4741 cggagaactg tgacccgcga cccagctggt tggtttggaa aactggaaca gagctcaata
4801 ctcaggcaaa tgtactggac taggggcccc aaccatgaag atccatctga atcaatgatt
4861 ccacactctc aaagacccat acaattgatg tccttactgg gagaggccgc actccacggc
4921 ccaacattct acagtaaaat cagcaaatta gtcattgcag agctaaaaga aggtggtatg
4981 gatttttacg tgcccaggca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtctaatga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctctggag cccgttgtcg gtgccgctat tgcggcgcct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtatc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atctgaatcc
5341 ctacctatct catttggcca gaatgtataa tggttatgca ggtggttttg aagtgcaggt
5401 gatcctcgcg gggaacgcgt tcaccgccgg aaaaattata tttgcagcag tcccaccaaa
5461 cttcccaact gaaggcctga gtcccagcca ggttactatg ttcccccaca taatagtgga
5521 tgttaggcaa ttggaacctg tattgatccc cttacctgat gttaggaata acttttatca
5581 ttataatcag tcaaatgatt ctaccattaa attgatagca atgctgtata caccacttag
5641 ggctaataat gctggggaag atgtcttcac agtttcttgt cgagttctca cgaggccatc
5701 ccctgatttt gattttatat ttttggtgcc acctacagtt gagtcaagaa ctaaaccatt
5761 tactgtccca atcttaactg ttgaagaaat gaccaattca agattcccca ttcctttgga
5821 aaaattgttc acgggcccca gcagtgcctt tgttgttcaa ccacaaaatg gcagatgcac
5881 gactgatggc gtgctcttag gcaccaccca actgtctcct gtcaacatct gcaccttcag
5941 aggggatgtc acccacattg caggttctcg tgattacaca atgaatttgg cttctctaaa
6001 ttggaacaat tatgacccaa cagaagaaat tccagcccct ttaggaaccc cagatttcgt
6061 gggaaagatc caaggtatgc tcactcaaac tacaaaggga gatggctcga cccgtggcca
6121 taaagctaca gtttacactg ggagtgcccc ctttactcca aagctgggca gtgttcggtt
6181 cagtactgac acagaaaatg attttgaaat tcaccaaaat acaaaattca ctccagtcgg
6241 tgtcatccag gatggtagca ccacccaccg aaatgaaccc caacaatggg tactcccaag
6301 ttattcaggt agagatgccc ataatgtaca cctagcccct gctgtagccc ccacttttcc
6361 gggtgaacaa cttcttttct tcaggtccac tatgcccgga tgcagcgggt atcccaacat
6421 ggatttggat tgcctgctcc cccaggagtg ggtgcagcac ttctaccaag aggcagctcc
6481 agcacaatct gatgtggctc tattgagatt tgtgaatcca gacacgggta gggttctgtt
6541 tgagtgcaaa ctccataaat caggctatgt cacagtggct cacaccggcc agcatgattt
6601 ggtcatcccc cccaatggtt attttaggtt tgattcctgg gttaatcaat tctatacact
6661 tgcccccatg ggaaatggaa cggggcgtag acgtgcttta taatggctgg agctttcttt
6721 gctggattgg catctgatgt ccttagctct ggacttggtt ccctgatcaa tgctggggct
6781 ggggctatca accaaaagat tgattttgaa aataacagaa aattgcagca agcttccttc
6841 cagtttagca gtaatctaca acaggcttcc tttcaacacg ataaagagat gctccaagca
6901 caaattgagg ccactaaaaa gttgcaacag gaaatgatga aagtcaaaca ggcaatgctc
6961 ttagaaggtg gattctctga aacagatgcg gcccgtgggg caatcaacgc ccctatgaca
7021 aaggctttgg attggagcgg aacaaggtac tgggcccctg atgctaggac tacaacatac
7081 aatgcaggcc gtttttccac ccctcaacct tcgggggcac cgccaggaag aaccaaccct
7141 aggactccaa cccccgctcg gggctccccc agcacatctt ctaatgcttc tactgctact
7201 tctatatatt caaatcaaac tgtttcaacg agacttggtt ctacagctgg ttctggcacc
7261 aacatctcga gtctcccgtc aactgcaagg actaggagtt gggttgagga tcaaaacaga
7321 aatttgtcac ctttcatgag gggggctcac aacatatcgt ttgtcacccc accatctagc
7381 agatcctcta gccaaggcac agtctcgacc gtgcctaaag aagttttgga ctcctggact
7441 ggcgctttca atacgcgcag gcagcctctc ttcgctcaca ttcgtaggcg aggggagtca
7501 cgggtgtaa
//