Typing tool
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Typing tool
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Complete norovirus genomes
| AB933676 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 1..5094
ORF2: 5078..6700
ORF3: 6700..7506
LOCUS AB933676 7506 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Niigata2/2010/JP genomic RNA, complete genome.
ACCESSION AB933676
VERSION AB933676.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Niigata2/2010/JP
ORGANISM Norovirus Hu/GII.4/Niigata2/2010/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7506)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7506
/organism="Norovirus Hu/GII.4/Niigata2/2010/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Niigata2/2010/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498670"
/geo_loc_name="Japan:Niigata"
/collection_date="2010"
CDS 1..5094
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30088.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDKMFSSMAVTFKRALGARP
QPPPREIPQRPPRPPTPELIKKIPPPPPNGEDEVVVSYSAKDGVSGLPELSTVRQPEE
TNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISL
AKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKL
RPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPEDL
VVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVA
KRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTMP
ELKQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLRC
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNKDGCP
KPKDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVT
GSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPS
LFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGT
VVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILGP
GSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWN
GESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLA
TMVRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDS
TQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGV"
CDS 5078..6700
/codon_start=1
/product="VP1"
/protein_id="BAS30089.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVSICTFRGDVTHIAGSRDYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
STAHRNEPQQWVLPSYSGRNVQNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6700..7506
/codon_start=1
/product="VP2"
/protein_id="BAS30090.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQVQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRNNPRTPTPARGSPSTSS
SAFTATSIYSNQTVSTRLGSTAGSGTNVSSPPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacaa aatgttttct agcatggctg tcacttttaa acgagccctc
121 ggggcgcgtc ctcagccccc cccgagggaa ataccacaaa gacccccacg accacctact
181 ccagaactga tcaaaaagat ccctcctccc ccgcccaacg gagaggatga agtagtggtt
241 tcttatagtg ccaaagatgg cgtttccggt ttacctgagc tttccaccgt cagacaaccg
301 gaagaaacca atacggcctt cagtgtccct ccactcaatc agagggagaa tagggatgct
361 aaggaaccac tgactggaac aatcctggaa atgtgggatg gagaaatcta ccattatggc
421 ctgtatgttg agcgaggtct tgtgctgggt gtgcacaaac caccagctgc cattagcctc
481 gccaaggtcg aactaacacc actctccttg ttctggagac ctgtgtacac tcctcagtac
541 ctcatctctc cggacactct caagaaatta cacggagaaa cattccccta cacagccttc
601 gacaacaatt gctatgcctt ttgttgctgg gtcctggacc taaacgactc gtggctgagt
661 aggagaatga tccagagaac aactggcttc ttcagaccct accaagattg gaataggaaa
721 cccctcccca ctatggatga ttccaaattg aagaaggtag ctaacatatt cctgtgcacc
781 ctgtcttcgc tatttactag gcccataaaa gacataatag ggaagttaag gcctctcaac
841 atcatcaaca tcctggcttc atgtgattgg actttcgcag gcatagtgga gtccttgata
901 ctcttggcag agctctttgg agtcttctgg acacccccag atgtgtctgc gatgattgcc
961 cccttactcg gtgatttcga gttacaagga cctgaggacc ttgtagtaga gctcgtccct
1021 gtagtaatgg ggggaattgg tttggtgcta ggattcacca aagagaagat tggaaaaatg
1081 ttgtcatctg ccgcatctac cttgagagct tgtaaagatc ttggtgcgta tgggctagag
1141 atcctaaaat tagtcatgaa gtggtttttc ccgaagaaag aggaagcaaa tgaactggct
1201 atggtgagat ccatcgagga tgcagtactg gaccttgagg caattgaaaa caaccatatg
1261 accaccttgc tcaaagacaa agacagcctg gcaacatata tgagaaccct tgacctcgag
1321 gaagagaaag ccagaaaact ctcaaccaag tctgcttcac ccgacatcgt gggcacaatc
1381 aacgcccttc tggcgagaat cgccgctgca cgctccctgg tgcaccgagc gaaggaggag
1441 ctttccagca gaccaagacc tgtagtcttg atgatatcag gcagaccagg aatagggaag
1501 acccaccttg ctagggaagt ggctaagaga atcgcagcct ccctcacagg agaccagcgt
1561 gtaggcctca tcccacgcaa tggcgtcgat cactgggatg cgtacaaggg ggagagggtc
1621 gtcctatggg acgactatgg aatgagcaat cccatccacg acgccctcag gctgcaagaa
1681 ctcgctgaca cttgccccct cactctaaat tgtgacagga ttgagaataa aggaaaggtc
1741 ttcgacagcg atgtcattat catcactact aacctggcca acccagcacc actggactat
1801 gtcaactttg aagcgtgctc gaggcgcatc gatttcctcg tgtatgcaga agcccccgag
1861 gtcgaaaagg caaagcgtga cttcccgggc caacctgata tgtggaaaaa cgctttcagt
1921 tctgatttct cacacataaa attggcactg gctccacaag gtggttttga taagaacggg
1981 aacaccccac acgggaaggg cgtcatgaag actctcacca ctggctccct cattgcccga
2041 gcatcagggc tgctccatga gaggttggat gagtttgaac tacagggccc agctcttacc
2101 accttcaact ttgaccgcaa caaagtgctt gcctttaggc agcttgctgc tgaaaacaaa
2161 tacgggttga tggacacaat gaaagttggg aggcagctca aggatgtcaa aaccatgcca
2221 gaacttaaac aagcactcaa gaatatctca atcaagaagt gccagattgt gtatagtggt
2281 tgcacctaca cacttgagtc tgatggcaag ggcaatgtga aagttgacag agttcagagc
2341 acctccgttc agaccaacaa tgagctggct ggcgccctgc accatttaag gtgcgccaga
2401 atcaggtact atgtcaagtg tgttcaggag gccctgtatt ctatcatcca gattgctggg
2461 gctgcatttg tcaccacgcg catcattaag cgcgtgaaca ttcaagactt gtggtccaag
2521 ccacaagtgg aaaacacaga ggaggccacc aacaaggacg ggtgcccaaa acccaaagat
2581 gatgaggagt tcgtcatttc atctgacgac attaaaactg agggtaagaa agggaagaac
2641 aagactggcc gtggcaagaa gcacacagcc ttctcaagta aaggtctcag tgatgaagag
2701 tatgatgagt acaagagaat tagagaggaa aggaatggca agtactccat agaagagtac
2761 cttcaggaca gggacaaata ctatgaggag gtggccattg ccagggcgac cgaggaagac
2821 ttctgtgaag aggaggaggc caagatccgg caaaggatct tcagaccaac aaggaaacaa
2881 cgcaaggaag aaagagcttc tctcggttta gtcacaggtt ctgaaattag gaagaggaac
2941 ccagaagact tcaagcctaa ggggaaacta tgggctgacg atgacagaag tgtggactac
3001 aatgaaaaac tcagctttga ggccccacca agcatctggt caaggatagt caactttggc
3061 tcaggttggg gcttctgggt ctcccccagc ctgttcataa catcaaccca cgtcataccc
3121 cagggcgcaa aggagttctt tggagtcccc atcaaacaaa ttcaggtaca caagtcaggc
3181 gaattctgtc gcttgaggtt cccaaagcca atcaggactg atgtaactgg catgatcttg
3241 gaagaaggtg cgcccgaagg caccgtggtc acactactca tcaaaaggtc tactggagaa
3301 ctcatgcccc tagcagctag gatggggacc catgcaacca tgaaaattca agggcgcact
3361 gttggaggtc agatgggcat gcttctgaca ggatccaacg ccaaaagcat ggatctgggc
3421 accacaccag gtgattgcgg ctgtccctac atctacaaga gaggaaatga ctatgtggtc
3481 attggagtcc acacggctgc cgctcgtggg ggaaacactg tcatatgtgc cacccaggga
3541 ggtgaggggg aagctacact tgaaggtggt gacagtaagg gaacatactg tggtgcacca
3601 atcctaggcc cagggagtgc cccaaaactt agcaccaaaa ccaaattctg gagatcatcc
3661 acagcaccac tcccacctgg cacctatgaa ccagcctacc ttggtggcaa ggaccccaga
3721 gtcaagggtg gcccctcgtt gcagcaagtc atgagggacc agctgaaacc atttacagag
3781 cctaggggta agccaccaaa gccaagtgtg ttagaagctg ccaagaaaac catcatcaat
3841 gtccttgaac aaacaattga cccacctgag aagtggtcgt tcgcacaagc ttgcgcgtcc
3901 cttgacaaga ccacttctag cggccatccg caccacatgc ggaaaaacga ctgctggaac
3961 ggggaatcct tcacaggcaa gctggcagac caggcttcta aggccaacct gatgtttgaa
4021 gaagggaaga acatgacccc agtctacaca ggtgcactta aggatgaatt agtcaaaact
4081 gacaagattt atggtaagat caagaagagg cttctctggg gctcggattt ggcaaccatg
4141 gtccggtgtg ctcgagcatt cggaggccta atggatgaac tcaaagcaca ctgtgtcaca
4201 cttcctatca gagttggtat gaatatgaat gaggatggcc ccatcatctt cgagaagcat
4261 tccaggtaca ggtaccacta tgatgctgat tactctcggt gggattcaac acaacagaga
4321 gccgtgctgg cagccgctct agaaatcatg gttaaattct cctcagaacc acatttggct
4381 caggtagtag cagaagacct tctttctcct agcgtggtgg atgtgggtga cttcacaata
4441 tcaatcaatg agggcctccc ctctggggtg ccctgcacct cccaatggaa ctccatcgcc
4501 cactggcttc tcactctctg tgcactctcc gaagttacaa atttgtcccc agacatcata
4561 caggctaatt ctctcttctc cttctatggt gatgatgaaa ttgttagtac agacataaaa
4621 ttggacccag agaagttgac agcaaagctt aaggaatacg ggctgaaacc aacccgccct
4681 gataaaactg aaggacctct tgttatttct gaagacttag atggtttgac tttcctgcgg
4741 agaactgtga cccgcgaccc agctggttgg tttggaaaac tggagcagag ttcaatactc
4801 aggcaaatgt actggactag gggccccaac catgaagatc catctgaatc aatgattcca
4861 cactctcaaa gacccataca attgatgtcc ttactgggag aggccgcact ccacggccca
4921 acattctaca gcaaaatcag caaattagtc attgcagaac taaaagaagg tggtatggat
4981 ttttacgtgc ccaggcaaga gccaatgttc agatggatga gattctcaga tctgagcacg
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt ctaatgacgc
5101 caacccatct gatgggtccg cagccaacct cgtcccagag gtcaacaatg aggttatggc
5161 tttggagccc gttgtcggtg ccgctattgc ggcgcctgta gcgggccaac aaaatgtgat
5221 tgacccctgg attagaaata attttgtaca agcccctggt ggagaattca cagtatcccc
5281 tagaaatgct ccaggtgaaa tactatggag cgcgccctta ggccctgatc tgaatcccta
5341 cctatcccat ttggccagaa tgtataatgg ttatgcaggt ggttttgaag tgcaggtgat
5401 cctcgcgggg aacgcgttca ccgccggaaa aattatattt gcagctgtcc caccaaattt
5461 tccaactgaa ggcttgagtc ccagccaggt cactatgttt ccccacataa tagtggatgt
5521 taggcaattg gaacctgtgt tgatcccctt acctgatgtt aggaataact tctaccacta
5581 taatcagtca aatgattcta ccattaaatt gatagcaatg ctgtatacac cacttagggc
5641 taataatgct ggggatgatg tcttcacagt ctcttgtcga gtcctcacga ggccatcccc
5701 tgattttgac tttatatttt tggtgccacc tacagttgag tcaagaacta aaccatttac
5761 tgtcccaatc ttaactgttg aagaaatgac caattcaaga ttccccattc ctttggaaaa
5821 attgtttacg ggtcccagca gtgcctttgt tgttcaacca caaaatggca gatgcacgac
5881 tgatggcgtg ctcttaggca ccacccaact gtctcctgtc agcatctgca ccttcagagg
5941 ggatgtcacc cacattgcag gttctcgtga ttacacaatg aatttggctt ctctaaattg
6001 gaacaactat gacccaacag aagaaattcc agcccctcta ggaaccccag atttcgtggg
6061 aaagatccaa ggtgtgctca ctcaaaccac aaagggagat ggttcgaccc gtggccataa
6121 agctacagtt tacactggga gtgccccctt tactccaaag ctgggcagtg ttcaattcag
6181 tactgataca gaaaatgatt ttgaaactca ccaaaacaca aaattcaccc cagtcggtgt
6241 catccaggat ggtagcaccg cccaccgaaa tgaaccccaa caatgggtgc tcccaagtta
6301 ttcaggtaga aatgtccaaa atgtacacct agcccctgct gtagccccca cgtttccggg
6361 tgaacaactt cttttcttta ggtccactat gcccggatgc agcgggtatc ccaacatgga
6421 tttggattgc ctactccccc aggagtgggt gcagcacttc taccaagagg cagctccagc
6481 acaatctgat gtggctctat tgagatttgt gaatccagac acgggtaggg tcctgtttga
6541 gtgcaagctt cataaatcag gctatgtcac agtggcccac accggccagc atgatttggt
6601 catccccccc aatggttatt ttaggtttga ttcctgggtt aatcaattct acacacttgc
6661 ccccatggga aatggaacgg ggcgtagacg tgctttataa tggctggagc tttctttgct
6721 ggattggcat ctgatgtcct tagctctgga cttggttccc taatcaatgc tggggctggg
6781 gctatcaacc aaaagatcga ttttgaaaat aacagaaaat tgcagcaagc ttccttccag
6841 tttagcagta atctacaaca ggcttccttt caacatgata aagagatgct ccaagtacaa
6901 attgaggcca ctaaaaagtt gcaacaggaa atgatgaaag ttaaacaggc aatgctttta
6961 gaaggtggat tctctgaaac agatgcagcc cgtggggcaa ttaacgcccc tatgacaaag
7021 gctttggact ggagcgggac aaggtactgg gcccctgatg ctaggactac aacatacaat
7081 gcaggccgtt tttccacccc tcaaccttcg ggggcactgc caggaagaaa caatcctagg
7141 actcctaccc ccgctcgggg ctcccccagc acatcttcta gtgcttttac tgctacttct
7201 atatattcaa atcaaacagt ttcaacgaga cttggttcta cagcaggttc tggcaccaat
7261 gtctcgagtc ccccgtcaac tgcaaggact aggagttggg ttgaggatca aaacagaaat
7321 ttgtcacctt tcatgagggg ggctcacaac atatcgtttg tcaccccacc atctagcaga
7381 tcctctagcc aaggcacagt ctcaaccgtg cctaaagaag ttttggactc ctggactggc
7441 gctttcaaca cgcgcaggca gcctctcttc gctcacattc gtaggcgagg ggagtcacgg
7501 gtgtaa
//