Typing tool
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Typing tool
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Complete norovirus genomes
| AB933655 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 1..5100
ORF2: 5081..6703
ORF3: 6703..7509
LOCUS AB933655 7509 bp RNA linear VRL 02-SEP-2015
DEFINITION Norovirus Hu/GII.4/Shimane2/2009/JP genomic RNA, complete genome.
ACCESSION AB933655
VERSION AB933655.1
KEYWORDS .
SOURCE Norovirus Hu/GII.4/Shimane2/2009/JP
ORGANISM Norovirus Hu/GII.4/Shimane2/2009/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Sato,H., Yokoyama,M. and Motomura,K.
TITLE Identification of strong evolutionary constraints on viral capsid
protein during divergent evolution of a norovirus pandemic lineage
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7509)
AUTHORS Sato,H., Nakamura,H. and Motomura,K.
TITLE Direct Submission
JOURNAL Submitted (09-MAY-2014) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Pathogen Genomics Center; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
FEATURES Location/Qualifiers
source 1..7509
/organism="Norovirus Hu/GII.4/Shimane2/2009/JP"
/mol_type="genomic RNA"
/strain="Hu/GII.4/Shimane2/2009/JP"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:1498649"
/geo_loc_name="Japan:Shimane"
/collection_date="2009"
CDS 1..5100
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAS30025.1"
/translation="MKMASNDASAAAVADSNNDTAKSSNDRMFSNMAVTLKRALGARP
KQPPPREIPQRPPRPPTPELVKKIPPPPPNGEDEVVVSYSARDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGAILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNISIKKCQIVYSGCTYTLESDGKGSVKVDRVQSTSVQTNNELVGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATSKDGC
PKPKDDEEFVISSDDIKSEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACTSLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKSMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
CDS 5081..6703
/codon_start=1
/product="VP1"
/protein_id="BAS30026.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSADFTPKLGSVQFGTDTENDFETHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNVHNVHLAPAVAPNFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6703..7509
/codon_start=1
/product="VP2"
/protein_id="BAS30027.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKVLDWSGTRYWAPDARTTTYNAGRFSTPQPSGALLGRINPRTPTPARGSPSTSS
NASTATSVYSNQTVSTRLGSTAGSGTNVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctgacagcaa caacgacacc
61 gcaaaatctt caaatgacag aatgttttct aacatggctg tcactcttaa acgagccctc
121 ggggcgcggc ctaaacagcc tcccccgagg gaaataccac aaagaccccc acgaccaccc
181 actccagaac tggtcaaaaa gatccctcct cccccgccca acggagagga tgaagtagtg
241 gtttcttata gcgccagaga tggtgtttcc ggtctgcctg agctttccac cgtcaggcaa
301 ccggaagaaa ccaatacggc cttcagtgtc cctccactca atcagaggga gaatagggat
361 gctaaggaac cactgactgg agcaattctg gaaatgtggg atggagaaat ttaccattat
421 ggcctgtatg ttgagcgagg tcttgtgctg ggtgtacaca aaccaccagc tgccattagc
481 ctcgccaagg tcgaactaac accactctcc ttgttctgga ggcctgtgta cactcctcag
541 tacctcatct ctccagacac tctcaagaaa ttgcacggag aaacatttcc ctacacagcc
601 tttgacaaca attgctatgc cttttgttgc tgggtcctgg atctaaacga ctcgtggctg
661 agtaggagaa tgatccagag aacaactggc ttcttcagac cctaccaaga ttggaatagg
721 aaacccctcc ccactatgga tgattccaaa ttaaagaagg tggctaacat attcctgtgc
781 gccctgtctt cgctattcac caggcccata aaagacataa taggaaagtt aaggcctctc
841 aacatcatca acatcctggc ttcatgtgat tggactttcg caggcatagt ggagtccttg
901 atactcttgg cagagctctt tggagtcttc tggacacccc cagatgtgtc tgcgatgatc
961 gcccccttac tcggtgattt tgagttacaa ggacctgagg accttgtagt ggagctcgtc
1021 cctgtagtaa tgggggggat tggtttggtg ctaggattca ccaaagagaa gattggaaaa
1081 atgttgtcat ctgctgcatc caccttgaga gcttgtaaag accttggtgc atatgggcta
1141 gagatcctaa agttagtcat gaagtggttc ttcccgaaga aagaggaagc gaatgaactg
1201 gctatggtga gatccatcga ggatgcagtg ctggaccttg aggcaattga aaacaaccat
1261 atgaccaccc tgctcaaaga caaagacagc ctggcaacct acatgagaac ccttgacctc
1321 gaggaagaga aagccagaaa actctcaacc aagtctgctt cacctgacat cgtgggcaca
1381 atcaacgccc ttctagcgag aatcgccgca gcacgctccc tagtgcaccg agcgaaagag
1441 gagctttcca gcagaccaag acctgtagtc ttgatgatat caggtaggcc aggaataggg
1501 aagacccacc ttgctaggga agtggctaag agaatcgcag cctccctcac aggagaccag
1561 cgtgtaggcc tcatcccacg caatggcgtt gatcactggg atgcgtacaa gggggagagg
1621 gtcgtcctgt gggacgacta tggaatgagc aatcccatcc acgacgccct caggctgcaa
1681 gaacttgctg acacttgccc cctcactcta aattgtgaca ggattgagaa taaaggaaag
1741 gtctttgaca gcgatgtcat cattatcact actaatctgg ccaacccagc accactggac
1801 tatgtcaact ttgaagcgtg ctcgaggcgc atcgatttcc tcgtgtatgc agaagccccc
1861 gaggtcgaaa aggcgaagcg cgactttccg ggtcaacctg acatgtggaa aaacgctttt
1921 agttctgatt tctcacacat aaaattggca ttggctccac aaggtggctt tgataagaac
1981 gggaacaccc cacacgggaa gggcgtcatg aagactctca ccactggctc cctcattgcc
2041 cgggcatcag gactgctcca tgagagattg gatgagtttg aactacaggg cccagctctt
2101 accaccttca actttgaccg caacaaagtg ctagccttca ggcagcttgc tgctgaaaac
2161 aagtatgggt tgatggacac aatgaaagtt gggaggcagc tcaaggatgt caaaaccatg
2221 ccagaactta aacaagcact caagaatatc tcaatcaaga agtgccagat tgtatacagt
2281 ggttgcacct acacacttga gtctgatggc aagggtagtg tgaaagttga cagagttcag
2341 agtacctccg ttcagaccaa caatgagctg gttggcgccc tgcaccatct aaggtgcgcc
2401 agaatcaggt actatgtcaa gtgtgttcag gaggctctgt attctatcat ccagattgct
2461 ggggctgcat ttgtcactac gcgcatcatt aagcgtgtga acattcaaga cttatggtcc
2521 aagccacaag tggaaaacac agaggaggct accagcaagg acgggtgccc aaaacccaaa
2581 gatgatgagg agttcgtcat ttcatctgac gacattaaat ctgagggtaa gaaagggaag
2641 aacaagactg gccgtggcaa gaagcacaca gccttttcaa gtaaaggtct cagtgatgaa
2701 gagtatgatg agtacaagag aattagagag gaaagaaatg gcaagtactc catagaagag
2761 tacctccagg acagggacaa atactatgag gaggtggcca ttgccagggc gaccgaggaa
2821 gacttctgtg aagaggaaga ggccaagatc cggcaaagga tcttcagacc aacaagaaaa
2881 caacgcaagg aagaaagagc ttctctcggt ttagtcacag gttctgaaat taggaagaga
2941 aacccagaag acttcaaacc taaggggaaa ctatgggctg acgatgacag aagtgtggac
3001 tacaatgaaa aactcagttt tgaggcccca ccaagcatct ggtcaagaat agtcaacttt
3061 ggctcaggtt ggggcttctg ggtttcccct agcctgttca taacatcaac ccacgtcata
3121 ccccagggcg caaaggagtt ctttggcgtc cccatcaaac aaattcaggt gcacaagtca
3181 ggcgaattct gtcgcttgag gttcccaaaa ccaatcagga ctgatgtgac tggcatgatc
3241 ttggaagaag gtgcacccga aggcacggtg gtcacactac tcatcaaaag gtctactgga
3301 gaactcatgc ccctagcagc cagaatgggg acccatgcaa ccatgaaaat tcaagggcgc
3361 actgttggag gtcagatggg catgcttctg acaggatcca acgccaaaag catggattta
3421 ggcaccacac caggtgattg cggctgtccc tacatctata agaggggaaa cgactatgtg
3481 gtcataggag tccacacagc tgccgctcgt gggggaaaca ctgtcatatg tgccacccag
3541 gggggtgagg gggaagctac acttgaaggt ggtgacagta agggaacata ctgtggtgca
3601 ccaatcctag gcccagggag tgccccaaaa cttagcacta aaaccaaatt ctggagatca
3661 tccacagcac cactcccacc tggcacctat gaaccagcct accttggtgg caaagacccc
3721 agagtcaagg gtggcccctc gttgcagcaa gtcatgaggg accagctgaa accatttaca
3781 gagcctaggg gtaagccacc aaagccaagt gtgttagaag ctgccaagaa aaccatcatc
3841 aatgtcctcg aacagacaat tgacccacct gagaaatggt cgtttgcaca agcttgcacg
3901 tcccttgaca agaccacttc tagcggccat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggaat ccttcacagg caagctggca gaccaggctt ccaaggccaa cctgatgttt
4021 gaagaaggga agagcatgac cccagtctac acaggtgcac ttaaggatga attagttaaa
4081 actgacaaga tttatggtaa gatcaagaag aggcttctct ggggctcgga tttagcaacc
4141 atgattcggt gtgctcgggc attcggaggc ctgatggatg aactcaaagc acactgcgtc
4201 acacttcctg tcagagttgg tatgaatatg aatgaggatg gccccatcat cttcgagaag
4261 cattctaggt acagatacca ctatgatgct gattactctc ggtgggattc aacacaacag
4321 agagccgtgc tggcagctgc tctagaaatc atggttaaat tctcctcaga accacatttg
4381 gctcaggtag tagcagaaga ccttctctct cctagcgtgg tggatgtggg tgacttcaca
4441 atatcaatca atgagggtct tccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcactct ctgtgcactc tccgaagtca caaacttgtc cccagacatc
4561 atacaggcta attctctctt ctccttctat ggtgatgatg aaattgttag cacagatata
4621 aaattagacc cagagaaatt gacagcaaag cttaaagaat atgggttgaa accaacccgc
4681 cctgacaaaa ctgaaggacc tcttgttatt tctgaagact tagacggttt gactttcctg
4741 cggagaactg tgacccgcga cccagctggt tggtttggga agctggagca gagctcaata
4801 ctcaggcaaa tgtactggac taggggcccc aaccatgaag acccatctga atcaatgatc
4861 ccacactctc aaagacccat acaattgatg tccttactgg gagaggccgc actccacggc
4921 ccaacattct acagtaaaat cagcaaatta gtcattgcag agctaaaaga aggtggcatg
4981 gatttttacg tgcccaggca agagccaatg ttcagatgga tgagattctc ggatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5101 cgccaaccca tctgatgggt ccgcagccaa cctcgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgttgtcg gtgccgctat tgcggcgcct gtagcgggcc aacaaaatgt
5221 gattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt tcacagtatc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atttgaatcc
5341 ctacctatct catttggcca gaatgtataa tggttatgca ggtggttttg aagtgcaagt
5401 gatcctcgcg gggaacgcgt tcaccgccgg gaaaattata tttgcagcag tcccaccaaa
5461 ttttccaact gaaggtttga gtcccagcca ggttactatg ttcccccaca taatagtaga
5521 tgttaggcaa ttggaacctg tgttgatccc tttacctgat gttaggaata acttctacca
5581 ctataatcag tcaaatgatt ctaccattaa attgatagca atgctgtaca caccacttag
5641 ggccaataat gctggggatg atgtcttcac agtctcttgt cgagtcctca cgagaccatc
5701 ccctgatttt gattttatat ttctggtgcc acccacagtt gagtcaagaa ccaagccatt
5761 cactgtccca atcttaactg ttgaagaaat gaccaattca agattcccca ttcctttgga
5821 aaaactgttc acgggtccca gcagtgcctt tgttgttcaa ccacaaaatg gcagatgcac
5881 tactgatggc gtgctcttag gcaccaccca actgtctcct gtcaacatct gcaccttcag
5941 aggagatgtc acccacattg cgggttcccg caattacaca atgaatttgg cctctctaaa
6001 ttggaacaat tacgacccaa cagaagaaat tccagccccc ctgggaactc cagattttgt
6061 gggaaagatc caaggtgtgc tcactcaaac cacaaaggga gacggctcga cccggggcca
6121 taaagctaca gtttacactg ggagtgccga ctttactcca aagctgggca gtgtccaatt
6181 tggtactgat acagaaaatg actttgaaac tcaccaaaac acaaaattca ccccagtagg
6241 tgtcatccag gatggtagca ccacccaccg aaatgaaccc caacaatggg tgctcccaag
6301 ttattcaggt agaaatgtcc ataatgtaca cctagcccct gctgtagctc ccaattttcc
6361 gggtgaacaa cttcttttct tcaggtccac tatgcccgga tgtagcgggt atcccaacat
6421 ggatttggat tgcctgctcc cccaggagtg ggtgcagcac ttctaccaag aggcagctcc
6481 agcacaatct gatgtggctc tattgagatt tgtgaatcca gacacgggta gggtcctgtt
6541 tgagtgcaaa ctccataaat caggctatgt cacagtggct cacaccggcc aacatgattt
6601 ggtcatcccc cccaatggct attttaggtt tgattcctgg gttaaccaat tctacacact
6661 tgcccccatg ggaaatggaa cggggcgtag acgtgcttta taatggctgg agctttcttt
6721 gctggattgg catctgatgt ccttagctct ggacttggtt ccctaatcaa tgctggggct
6781 ggggctatca accaaaagat tgattttgaa aataatagaa aattgcagca agcttccttc
6841 cagtttagca gtaacctaca acaggcttcc tttcaacacg ataaagagat gctccaagca
6901 caaattgagg ccactaaaaa gttgcaacaa gaaatgatga aagtcaaaca ggcaatgctc
6961 ttagaaggtg gattctctga aacagatgca gcccgtgggg caatcaacgc ccccatgaca
7021 aaggttttgg actggagcgg aacaaggtac tgggcccctg atgctaggac tacaacatac
7081 aatgcaggcc gcttttccac ccctcaacct tcgggggcac tgctaggaag aatcaatccc
7141 aggactccca cccccgctcg gggctcccct agcacatctt ccaatgcttc tactgctact
7201 tctgtatatt caaatcaaac tgtttcaacg agacttggtt ctacagctgg ttctggcacc
7261 aatgtctcga gtcttccgtc aactgcaagg actaggagtt gggttgagga tcaaaacaga
7321 aatttgtcac ccttcatgag gggggctcac aacatatcgt ttgtcacccc accatctagc
7381 agatcctcca gccaaggcac agtctcaacc gtgcctaaag aaattttgga ctcctggact
7441 ggcgctttca acacgcgcag gcagcctctc ttcgctcaca ttcgtaagcg aggggagtca
7501 cgggtgtaa
//