Typing tool
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Typing tool
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Complete norovirus genomes
| AB447446 | GII.4 Den Haag | |
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| GII.P4 Den Haag |
ORF1: 3..5102
ORF2: 5083..6705
ORF3: 6705..7511
LOCUS AB447446 7511 bp RNA linear VRL 05-NOV-2008
DEFINITION Norovirus Hu/GII-4/Aichi3/2006/JP genomic RNA, complete genome.
ACCESSION AB447446
VERSION AB447446.1
KEYWORDS .
SOURCE Norovirus Hu/GII-4/Aichi3/2006/JP
ORGANISM Norovirus Hu/GII-4/Aichi3/2006/JP
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1
AUTHORS Motomura,K., Oka,T., Yokoyama,M., Nakamura,H., Mori,H., Ode,H.,
Hansman,G.S., Katayama,K., Kanda,T., Tanaka,T., Takeda,N. and
Sato,H.
CONSRTM and the Norovirus Surveillance Group of Japan
TITLE Identification of monomorphic and divergent haplotypes in the
2006-2007 norovirus GII/4 epidemic population by genomewide tracing
of evolutionary history
JOURNAL J. Virol. 82 (22), 11247-11262 (2008)
PUBMED 18768979
REFERENCE 2 (bases 1 to 7511)
AUTHORS Motomura,K. and Sato,H.
TITLE Direct Submission
JOURNAL Submitted (14-JUL-2008) Contact:Kazushi Motomura National Institute
of Infectious Diseases, Center for Pathogen Genomics; Gakuen 4-7-1,
Musashi-Murayama, Tokyo 208-0011, Japan
COMMENT These sequences were determined at our laboratory.
FEATURES Location/Qualifiers
source 1..7511
/organism="Norovirus Hu/GII-4/Aichi3/2006/JP"
/mol_type="genomic RNA"
/strain="Hu/GII-4/Aichi3/2006/JP"
/isolation_source="stool"
/db_xref="taxon:546970"
/geo_loc_name="Japan:Aichi"
CDS 3..5102
/note="contains N-terminal, NTPase, 3A, VPg, 3Cpro and
3Dpol"
/codon_start=1
/product="polyprotein"
/protein_id="BAG70484.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDKMFSSMAVTFKRALGARP
KQPPPREIPQGPPRPPTPELVKKIPPPPPNGEDEVVVSYSAKDGVSGLPELSTVRQPE
ETNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
FAKVELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LRPLNIINILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFELQGPED
LVVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIRLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVKTM
PELKQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSTSVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIIKRVNIQDLWSKPQVENTEEATNEDGC
PKPKDNEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVVTLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGGEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKDGPSLQQVMRDQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPSESMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
CDS 5083..6705
/codon_start=1
/product="VP1"
/protein_id="BAG70485.1"
/translation="MKMASNDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGEDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGSRNYTMNLASLNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTKGDGSTRGHKATVYTGSAPFTPKLGSVQFSTDTENDFETHQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNVQNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
CDS 6705..7511
/codon_start=1
/product="VP2"
/protein_id="BAG70486.1"
/translation="MAGAFFAGLASDVLSSGLGSLINAGAGAINQKIDFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRINPRTPTPARGSPSTSS
DASTATSIYSNQTVSTRLGSTAGSGTNVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRRRGESRV"
ORIGIN
1 gaatgaagat ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca
61 ccgcaaaatc ttcaagtgac aaaatgtttt ctagcatggc tgtcactttt aaacgagccc
121 tcggggcgcg gcctaaacag ccccccccga gggaaatacc acaaggaccc ccacgaccac
181 ctactccaga actggtcaaa aagatccctc ctcccccgcc caacggagag gatgaagtag
241 tggtttctta tagtgccaaa gatggcgttt ccggtttacc tgagctttcc accgtcaggc
301 aaccggaaga aaccaatacg gccttcagtg tccctccact caatcagagg gagaataggg
361 atgctaagga accactgact ggaacaattc tggaaatgtg ggatggagaa atctaccatt
421 atggcctgta tgttgagcga ggtcttgtgc tgggtgtgca caaaccacca gctgccatta
481 gcttcgccaa ggtcgaacta acaccactct ccttgttctg gagacctgtg tacactcctc
541 agtacctcat ctctccagac actctcaaga aattacacgg agaaacattt ccctacacag
601 ccttcgacaa caattgctat gccttttgtt gctgggtcct ggatctaaac gactcgtggc
661 tgagtaggag aatgatccag agaacaactg gcttcttcag accctaccaa gattggaata
721 ggaaacccct ccccactatg gatgactcca aattaaagaa ggtagctaac atattcctgt
781 gcaccctgtc ttcgctattc accaggccca taaaagacat aatagggaag ttaaggcctc
841 tcaacatcat caacatcctg gcttcatgtg attggacttt cgcaggcata gtggagtcct
901 tgatactctt ggcagagctc tttggagtct tctggacacc cccagatgtg tctgcgatga
961 ttgccccctt actcggtgat ttcgagttac aaggacctga ggaccttgta gtggagctcg
1021 tccctgtagt aatgggggga attggtttgg tgctaggatt caccaaagag aagattggaa
1081 aaatgttgtc atctgctgca tctaccttga gagcttgtaa agatcttggt gcatatgggc
1141 tagagatcct aaagttagtc atgaagtggt tcttcccgaa gaaagaggaa gcaaatgaac
1201 tggctatggt gagatccatc gaggatgcag tactggacct tgaggcaatt gaaaacaacc
1261 atatgaccac cttgctcaaa gacaaagaca gcctggcaac ctatatgaga acccttgacc
1321 tcgaggaaga gaaagccaga aaactctcaa ccaagtctgc ttcacctgac atcgtgggca
1381 caatcaacgc ccttctggcg agaatcgccg ctgcacgctc cctggtgcac cgagcgaagg
1441 aggagctttc cagcagacca agacctgtag tcttgatgat atcaggcaga ccaggaatag
1501 ggaagaccca ccttgctagg gaagtggcta agagaatcgc agcctccctc acaggagacc
1561 agcgtgtagg cctcatccca cgcaatggcg tcgatcactg ggatgcgtac aagggggaga
1621 gggtcgtcct atgggacgac tatggaatga gcaatcccat ccacgacgcc ctcaggctgc
1681 aagaactcgc tgacacttgc cccctcactc taaattgtga caggattgag aataaaggaa
1741 aggtctttga cagcgatgtc atcattatca ctactaacct ggccaaccca gcaccactgg
1801 actatgtcaa ctttgaagcg tgctcgaggc gcatcgattt cctcgtgtat gcagaagccc
1861 ccgaggtcga aaaggcgaag cgtgacttcc cgggccaacc tgacatgtgg aaaaacgctt
1921 ttagttctga tttctcacac ataagattgg cactggctcc acaaggtggc tttgataaga
1981 acgggaacac cccacacggg aagggcgtca tgaagactct caccactggc tccctcattg
2041 cccgggcatc agggctgctc catgagagat tggatgagtt tgaactacag ggcccagctc
2101 ttaccacctt caactttgac cgcaacaaag tgcttgcctt caggcagctt gctgctgaaa
2161 acaaatacgg gttgatggac acaatgaaag ttgggaggca gctcaaggat gtcaaaacca
2221 tgccagaact taaacaagca ctcaagaata tctcaatcaa gaagtgccag attgtgtata
2281 gtggttgcac ctacacactt gagtctgatg gcaagggcaa tgtgaaagtt gacagagttc
2341 agagcacctc cgttcagacc aacaatgagc tggctggcgc cctgcaccat ctaaggtgcg
2401 ccagaatcag gtactatgtc aagtgtgttc aggaggccct gtattctatc atccagattg
2461 ctggggctgc atttgtcacc acgcgcatca tcaagcgtgt gaacattcaa gacttatggt
2521 ccaagccaca agtggaaaac acagaggagg ctaccaacga ggacgggtgc ccaaagccca
2581 aagataatga ggagttcgtc atttcgtctg acgacattaa aactgagggt aagaaaggga
2641 agaacaagac tggccgtggc aagaagcaca cagccttctc aagtaaaggt ctcagtgatg
2701 aagagtatga tgagtacaag agaattagag aggaaaggaa tggcaagtac tccatagaag
2761 agtaccttca ggacagggac aaatactatg aggaggtggc cattgccagg gcgaccgagg
2821 aagacttctg tgaagaggag gaggccaaga tccggcaaag gatcttcaga ccaacaagga
2881 aacaacgcaa ggaagaaaga gcttctctcg gtttagtcac aggttctgaa attaggaaaa
2941 ggaacccaga agacttcaag cctaagggga aactatgggc tgacgatgac agaagtgtgg
3001 actacaatga aaaactcagc tttgaggccc caccaagcat ctggtcaagg atagtcaact
3061 ttggctcagg ttggggcttc tgggtctccc ccagcctgtt cataacatca acccacgtca
3121 taccccaggg cgcaaaggag ttctttggag tccccatcaa acaaattcag gtacacaagt
3181 caggcgaatt ctgtcgcttg aggttcccaa aaccaatcag gactgatgtg actggcatga
3241 tcttggaaga aggtgcgccc gaaggcaccg tggtcacact actcatcaaa aggtctactg
3301 gagaactcat gcccctagca gctagaatgg ggacccatgc aaccatgaaa attcaagggc
3361 gcactgttgg aggtcagatg ggcatgcttc tgacaggatc caacgccaaa agcatggatc
3421 taggcaccac accaggtgat tgcggctgtc cctacatcta caagagagga aatgactatg
3481 tggtcattgg agtccacacg gctgccgctc gtgggggaaa cactgtcata tgtgccaccc
3541 aggggggtga gggggaagct acacttgaag gtggtgacag taagggaaca tactgtggtg
3601 caccaatcct aggcccaggg agtgccccaa aacttagcac caaaaccaaa ttctggagat
3661 catccacagc accactccca cctggcacct atgaaccagc ctaccttggt ggcaaggacc
3721 ccagagtcaa ggatggcccc tcgttgcagc aagtcatgag ggaccagctg aaaccattta
3781 cagagcctag gggtaagcca ccaaagccaa gcgtgttaga agctgccaag aaaaccatca
3841 tcaatgtcct tgaacaaaca attgacccac ctgagaagtg gtcgttcgca caagcttgcg
3901 cgtcccttga caagaccact tctagcggcc atccgcacca catgcggaaa aacgactgct
3961 ggaacgggga atccttcaca ggcaagctgg cagaccaggc ttccaaggcc aacctgatgt
4021 ttgaagaagg gaagaacatg accccagtct acacaggtgc acttaaagat gaattagtca
4081 aaactgacaa aatttatggt aagatcaaga agaggcttct ctggggctcg gatttagcaa
4141 ccatgatccg gtgtgctcga gcattcggag gtctaatgga tgaactcaaa gcacactgtg
4201 tcacacttcc tatcagagtt ggtatgaata tgaatgagga tggccccatc atcttcgaga
4261 agcattccag gtacagatac cactatgatg ctgattactc tcggtgggat tcaacacagc
4321 agagagccgt gctggcagct gctctagaaa tcatggttaa attctcctca gaaccacatt
4381 tggctcaggt agtagcagaa gaccttcttt ctcctagcgt ggtggatgtg ggtgacttca
4441 caatatcaat caacgagggt cttccctctg gggtgccctg cacctcccaa tggaactcca
4501 tcgcccactg gcttctcact ctctgtgcac tctccgaagt tacaaatttg tccccagaca
4561 tcatacaggc taattctctc ttctccttct atggtgatga tgaaattgtt agtacagaca
4621 taaaattaga cccagagaag ttgacagcaa agcttaagga atacgggttg aaaccaaccc
4681 gccctgataa aactgaagga cctcttgtta tttctgaaga cttagatggt ttgactttcc
4741 tgcggagaac tgtgacccgc gacccagctg gttggtttgg aaaactggag cagagctcaa
4801 tactcaggca aatgtactgg actaggggcc ccaaccatga agatccatct gaatcaatga
4861 ttccacactc tcaaagaccc atacaattga tgtccttact gggagaggcc gcactccacg
4921 gcccaacatt ctacagtaaa atcagtaaat tagtcattgc agagctaaaa gaaggtggta
4981 tggattttta cgtgcccagg caagagccaa tgttcagatg gatgagattc tcagatctga
5041 gcacgtggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
5101 gacgccaacc catctgatgg gtccgcagcc aacctcgtcc cagaggtcaa caatgaggtt
5161 atggctttgg agcccgttgt cggtgccgct attgcggcgc ctgtagcggg ccaacaaaat
5221 gtaattgacc cctggattag aaataatttt gtacaagccc ctggtggaga gttcacagta
5281 tcccctagaa acgctccagg tgaaatacta tggagcgcgc ccttaggccc tgatctgaat
5341 ccctacctat ctcatttggc cagaatgtat aatggttatg caggtggttt tgaagtgcag
5401 gtgatcctcg cggggaacgc gttcaccgcc ggaaaaatta tatttgcagc agtcccacca
5461 aattttccaa ctgaaggctt gagtcccagc caggtcacta tgttccccca cataatagtg
5521 gatgttaggc aattggaacc tgtgttgatc cccttacctg atgttaggaa taacttctat
5581 cactataatc agtcaaatga ttctaccatt aaattgatag caatgctgta tacaccactt
5641 agggctaata atgctgggga agatgtcttc acagtctctt gtcgagttct cacgaggcca
5701 tcccctgatt ttgattttat atttttggtg ccacctacag ttgagtcaag aactaaacca
5761 tttactgtcc caatcttaac tgttgaagaa atgaccaatt caagattccc cattcctttg
5821 gaaaaattgt tcacgggtcc cagcagtgcc tttgttgttc aaccacaaaa tggcagatgc
5881 acgactgatg gcgtgctctt aggcaccacc caactgtctc ctgtcaacat ctgcaccttc
5941 agaggagatg tcacccacat tgcaggttct cgtaattaca caatgaattt ggcttctcta
6001 aattggaaca attatgaccc aacagaagaa attccagccc ctctaggaac tccagatttc
6061 gtgggaaaga tccaaggtgt gctcactcaa accacaaagg gagatggctc gacccgtggc
6121 cataaagcta cagtttacac tgggagtgcc ccctttactc caaagctggg cagtgttcag
6181 ttcagtactg atacagaaaa tgattttgaa actcaccaaa acacaaaatt caccccagtc
6241 ggtgtcatcc aggatggtag caccacccac cgaaatgaac cccaacaatg ggtgctccca
6301 agttattcag gtagaaatgt ccaaaatgta cacctagccc ctgctgtagc ccccactttt
6361 ccgggtgaac aacttctttt ctttaggtcc actatgcccg gatgcagcgg gtatcccaac
6421 atggatttgg attgcctact cccccaggag tgggtgcagc acttctacca agaggcagct
6481 ccagcacaat ctgatgtggc tctattgaga tttgtgaatc cagacacggg tagggtcctg
6541 tttgagtgca aactccataa atcaggctat gtcacagtgg ctcacaccgg ccagcatgat
6601 ttggttatcc cccccaatgg ttattttagg tttgattcct gggttaatca attctacaca
6661 cttgccccca tgggaaatgg aacggggcgt agacgtgctt tataatggct ggagctttct
6721 ttgctggatt ggcatctgat gtccttagct ctggacttgg ttccctaatc aatgctgggg
6781 ctggggctat caaccaaaag attgattttg aaaataacag aaaattgcag caagcttcct
6841 tccagtttag cagtaatcta caacaggctt cctttcaaca tgataaagag atgctccaag
6901 cacaaattga ggccactaaa aagttgcaac aggaaatgat gaaagtcaaa caggcaatgc
6961 tcttagaagg tggattctct gaaacagatg cagcccgtgg ggcaatcaac gcccctatga
7021 caaaggcttt ggactggagc ggaacaaggt actgggcccc tgatgctagg actacaacat
7081 acaatgcagg ccgtttttcc acccctcaac cttcgggggc actgccagga agaatcaatc
7141 ccaggactcc tacccccgct cggggctccc ccagcacatc ttctgatgct tctactgcta
7201 cttctatata ttcaaatcaa actgtttcaa cgagacttgg ttctacagct ggttctggca
7261 ccaatgtctc gagtctcccg tcaactgcaa ggactaggag ttgggttgag gatcaaaaca
7321 gaaatttgtc acctttcatg aggggggctc acaacatatc gtttgtcacc ccaccatcta
7381 gcagatcctc tagccaaggc acagtctcaa ccgtgcctaa agaagttttg gactcctgga
7441 ctggcgcttt caacacgcgc aggcagcctc tcttcgctca cattcgtagg cgaggggagt
7501 cacgggtgta a
//