Typing tool
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Typing tool
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Complete norovirus genomes
| PZ580604 | GII.17 | |
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| GII.P17 |
ORF1: 1..5013
ORF2: 4994..6610
ORF3: 6610..7389
LOCUS PZ580604 7389 bp RNA linear VRL 01-JUL-2026
DEFINITION Norovirus GII isolate Wuhan/P4 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION PZ580604
VERSION PZ580604.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7389)
AUTHORS Luo,D.
TITLE Direct Submission
JOURNAL Submitted (26-JUN-2026) Center for Emerging Infectious Diseases,
Wuhan Institute of Virology, CAS, No. 262, Jinlong Street,
Jiangxia, Wuhan, Hubei 430207, China
COMMENT ##Assembly-Data-START##
Assembly Method :: Megahit v. v1.2.9
Sequencing Technology :: DNBSEQ-T7
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7389
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Wuhan/P4"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Hubei, Wuhan"
/collection_date="30-May-2025"
/note="genotype: GII"
gene <1..5013
/gene="ORF1"
CDS <1..5013
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YFI91449.1"
/translation="MTVTFKKALGARSKQPPPGETKQTLRPPRPPTPELVKKIPPPPP
NGEDEPKVTYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLSQREVGEAREPLPGSILE
MWDGEIYHYGLYVERGLVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQYLIAPETLK
NLNGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMD
EPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAE
LFGVFWTPPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLS
SAATTLRACKDLGSYGLEILKLVMKWFFPKKEEANDLAMVRAIEDAVLDLEAIENNHM
TTLLKDKDALATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAK
EELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYK
GERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLAN
PAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAP
QGGFDKSGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGPNLPTFNFDRNKVA
AFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESD
GRNKVVVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTT
RIARRMNISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGR
GKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFC
EEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDY
NERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHK
SGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKI
QGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTV
ICATQGGEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPA
YLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPE
KWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMRPV
YTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVG
MNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVA
EDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQA
NSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVVSEDLNGLTFLR
RTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLH
GPSFYSKVSKLVISELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDG
VE"
mat_peptide <1..903
/gene="ORF1"
/product="p48"
mat_peptide 904..2001
/gene="ORF1"
/product="NTPase"
mat_peptide 2002..2538
/gene="ORF1"
/product="p22"
mat_peptide 2539..2937
/gene="ORF1"
/product="VPg"
mat_peptide 2938..3480
/gene="ORF1"
/product="Pro"
mat_peptide 3481..5010
/gene="ORF1"
/product="RdRp"
gene 4994..6610
/gene="ORF2"
CDS 4994..6610
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YFI91450.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6610..7389
/gene="ORF3"
CDS 6610..7389
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YFI91451.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 atgactgtta cttttaagaa agccctcggg gcgcggtcta agcagccgcc cccgggagaa
61 acaaaacaaa cactaagacc accaaggccg ccgacaccgg aattggtgaa gaagataccc
121 ccaccccccc ccaatggcga ggatgaacca aaggtaacgt ataaggtggg agaaggtgtg
181 tctgggctgc ccgacttaac aaccgtggca caacctgacg cacagaacac agcctatagt
241 gtccccccac ttagccagag agaggtcggc gaagctagag aaccgttgcc tggctccatt
301 ctggaaatgt gggatggtga gatctaccac tatgggctgt atgttgagcg ggggcttgtg
361 ctgggagtgc acaaaccacc tgctgcaata agccttgcca aaattgagtt aacaccgctg
421 tctctttact ggagagtggt ctacactccc cagtacttga tagctccaga gaccctcaag
481 aatttaaatg gagagacttt cccatacacg gcctttgaca acaactgtta tgccttctgt
541 tgttgggttc tagacctcaa cgactcctgg cttagcagaa gaatggtcca aagaacaacc
601 ggattcttca gaccgtatca ggactggaac agaaaaccct taccaaccat ggatgaacca
661 aaaatcaaga aggccgcgaa tgctgttctg tgtgctctct cctcactctt cactaggccc
721 atcaaagatg tcattggaaa gcttaagcca ctaaacatta tgaacatact ggcaacttgt
781 gattggactt ttgcgggcat agtggaatcc atgatccttc ttgctgaact ctttggggtg
841 ttctggacgc ccccagatgt gtctgcaata attgctccct tactcggtga ctacgagatg
901 caaggccccg aagacctggc cgtggaactt gtgcccgtgg taatgggagg aataggtttg
961 gtgttaggat tcaccaagga aaagatcggc aagatgcttt catcagctgc aaccacactc
1021 agggcctgta aggatctagg atcttatggg ttggagatac tcaaactggt catgaagtgg
1081 ttcttcccca agaaggagga ggccaacgat ttagccatgg tgagggccat tgaggatgca
1141 gttctggatt tggaggcaat agaaaacaac cacatgacca ctctccttaa ggacaaagac
1201 gccctggcca catacatgag gactcttgac ttagaagaag aaaaagcaag gaaactatct
1261 tccaaatcgg cgtcacctga catcgtgggc acagtaaacg cattattggc aagaatagca
1321 gccgccaggt cactggtcca caaggctaag gaggagctct cgagcagaca gagacctgtt
1381 gttgtaatga tatcaggtag gccaggtata ggaaagaccc atctggccag agagctagcc
1441 aagaaggttg cgtcaacact gtcaggcgac caaaggattg gactgatacc cagaaatggc
1501 gtcgaccatt gggacgccta caaaggagag cgggtggttc tgtgggatga ctatggcatg
1561 agcaacccta tacaggacgc actgaggctc caagaattgg ctgacacctg tcctttgacc
1621 ctaaattgtg acagaattga aaacaaagga aaagtgttcg acagtgacgc cataatcata
1681 acgaccaacc ttgcaaaccc agcaccattg gattatgtca actttgaggc ttgttccaga
1741 cgcatagact tcttggtgta tgcagacgca cctgacatcg agaaggctaa gcgtgacttt
1801 cctggccaac cagatatgtg gaaagaccat tacagaccag acttctcaca cattaaactt
1861 cagctcgcac cacagggagg ctttgataag agtggcaaca ccccacatgg caaaggcgtg
1921 gttaagtctc tgacgattgg ctctctgatc gccagggctt ctggcttgct ccatgagaga
1981 atggatgaat tcgagctcca aggccccaac ttaccaacct tcaatttcga ccgtaacaaa
2041 gtcgccgcct tcagacagtt ggcagctgaa aacaaatacg gccttatgga cacactgagg
2101 gtcggcaacc aactgaaaag tgtcaaaacc ctggatgagt tgaagcaggc cataaagaac
2161 atcaccatca agaagtgcca gatagtgtac aatggatgca cctacaccat ggaatctgat
2221 gggaggaaca aggttgtggt tgaaaaggtt caaaatgcaa cagtccaaac caacaatgaa
2281 cttgcaggag cactccacca cctgagatct gcaagaataa ggtattatgt caaatgtttc
2341 caagaagcta tttactctat actccaaatt gctggtgcag ccttcgtcac cacacgcatc
2401 gcgaggcgca tgaacatctc aaacctctgg tcgaagccac ccgtcgaaga gggtgatgag
2461 cctgaagaca aaggggggtg ccccaagccc agggatgaag atgacctcac tattgactcc
2521 aaagacatta aagcagaagg taagaagggc aagaacaaat ctggccgggg caagaaacac
2581 acagctttct catccaaggg cctcagtgat gaagagtacg atgagtacaa gagaatcagg
2641 gaggagagaa atggcaagta ctcaatagaa gaatacctcc aggataggga tagatactat
2701 gaagagcttg ccattgctaa ggccactgag gaagacttct gtgaagagga ggaaatcaaa
2761 attcgccaga gaatcttccg gcccaccagg aagcagcgga aagaggaaag agccacgctt
2821 gggctcgtca caggatcgga aatcagaaag aggaacccag atgattttaa gccaaaagga
2881 aaattgtggg ctgatgacaa caggagtgtg gactacaatg agaggataga ttttgaggct
2941 cccccaagtg tttggtctag gatagtcaac tttggtacag gatggggatt ctgggtctcc
3001 ccaagtctct ttataacttc aacacatgtc ataccaaaag gaattactga ggcctttgga
3061 gttcccatta accaaattca aattcacaaa tctggagagt tttgccgctt gcggtttcca
3121 aaaccaatca ggccagacgt gagtggaatg atcttggaag agggtgcccc tgaaggcact
3181 gttgtttcca ttctcatcaa gaggacgaca ggggaactga tgcctctcgc agtcagaatg
3241 ggaactcatg ccacaatgaa aatccaaggt agaacggtgg gcggtcaaat gggcatgctt
3301 ctcactggct caaacgccaa aagcatggac ctaggcacaa caccaggtga ctgtgggtgc
3361 ccatacatat acaaaagggg caatgacttc gtggtcattg gggtgcacac tgcagcagcc
3421 cgtggaggta acacggtcat atgtgccaca caggggggtg aaggcgaagc caccctcgaa
3481 ggaggtgaca acaagggcac ctattgtgga gcccccatct tgggtcctgg caacgcacca
3541 aaattgagca caaaaacaaa attctggaga tcttctaacg cgccgctccc gccaggcacc
3601 tacgaaccag cataccttgg tggaaaagac ccgcgtgtga agggaggccc atctctacaa
3661 caggttatga gagaccaact caaacctttt acagagccca gagggaagcc accaaaacca
3721 agtgtcctag aatcagcaaa gaagaccatc attaatgttc tggaacaaac cattgacccc
3781 cctgaaaagt ggtcatatgc ccaagcttgt gcatccctcg acaagacaac ctccagtgga
3841 tacccgcatc acgtccggaa gaatgactac tggagtggtg aatccttcac ggggaaactt
3901 gcagaccagg cctcaaaagc aaatctcatg tatgaggagg gtaagcacat gcgaccagtt
3961 tacaccgcag cacttaaaga cgagctcgtg aaaactgaca aaatttatgg caagatcaag
4021 aaaagactcc tgtggggctc tgacctgtcc accatgattc gatgcgccag ggcatttggt
4081 ggcctcatgg acgagctcaa agcaaattgt atcacactcc ctatcagagt tggtatgaac
4141 atgaatgaag atggtcccat aatatttgaa aagcactcca ggtacaggta ccactatgat
4201 gctgattatt cccgctggga ttccacacaa cagcgggcag tgctggaagc ggcacttgaa
4261 atcatggtga gattttctgc tgagccacag ttggcacaaa tagtggcaga ggacctgcta
4321 tcaccaagtg tggttgatgt gggcgatttc aaaattacta tcaatgaagg cctaccatct
4381 ggcgtgcctt gcacttcaca atggaattct attgcccact ggttactcac cctatgtgcc
4441 ctgtctgaag tgacaggact aggccctgac atcatacaag ccaactccat gtactctttc
4501 tatggtgatg atgagattgt gagcacagac ataaaattgg acccagagaa attgactgca
4561 aaactcaaag aatatggtct taaacccacc cggcctgaca agactgaggg gccactggta
4621 gttagtgagg acctgaatgg gttgactttc ctccgccgaa cagtcacccg cgatccagcg
4681 ggttggtttg gaaagttgga ccaaaactcc atcctcagac agctgtactg gacaagggga
4741 cccaaccatg aagaccccag tgagactatg ataccacacg cacagagacc tgtgcagctc
4801 atggcattgc taggagaatc ctccctacat ggaccctcat tttacagcaa ggtcagcaaa
4861 ctggttatat ctgaacttaa agagggagga atggattttt atgtgcccag acaagagcca
4921 atgttcaggt ggatgaggtt ctcagatcta agcacatggg agggcgatcg caatctggct
4981 cccagttttg tgaatgaaga tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc
5041 tggtctcgta ccagagggca ataacgagac ccttccccta gaaccagttg cgggcgcagc
5101 catagccgca cccgtcactg gccaaaataa tataattgac ccctggatta gaacaaattt
5161 tgtgcaagca ccaaatggag agttcacagt gtcacccaga aactcccctg gagaaatttt
5221 actaaaccta gagttgggcc ctgatctgaa cccttatttg gctcatttgt caaggatgta
5281 taatgggtat gctggtggag ttgaagtcca ggttctcctg gcagggaacg cgttcactgc
5341 cgggaagatc ctcttcgccg ctgtcccgcc aaattttccg gtggaattct taagcccagc
5401 ccagattaca atgctcccac atataatagt agatgttagg actcttgaac caattatgat
5461 cccattacct gatgttagga atacattctt ccattataat aatcagccca acagccgcat
5521 gagattagtg gctatgctct acacccccct tagatctaat ggctcaggtg atgatgtttt
5581 cactgtttct tgcagggttt tgactaggcc tactcctgat tttgagttca cttatctagt
5641 gccaccctct gttgaatcta agactaaacc cttttcttta cccattctaa ccctttctga
5701 gctcacaaat tcgaggttcc cggtccccat cgattcgctt ttcaccgccc aaaataatgt
5761 gttgcaggtg cagtgtcaaa atggcaggtg cacacttgac ggtgagctac aaggcacaac
5821 ccagttgctc ccatctggca tctgtgcgtt caggggacgg gtgacagcag aaactgacaa
5881 tcctgacaag tggcacatgc aactgcaaaa ccttaatggc acaacatatg acccaactga
5941 tgatgtgcca gccccactgg gtacacctga tttcaagggc gtcgtgttcg ggatggcaag
6001 ccaaagaaat gtgggtaacg acgcgcccgg ctcaaccagg tcccatgagg cggtgatttc
6061 aacctacagc cccagatttg ttcctaaatt aggctctgtc aatttcaaaa gcaatgacga
6121 tgatttccaa ttgcagccaa caagattcac accagtgggc attaatgatg atggcaacca
6181 accattcaga caatgggaac taccagatta ttcaggagtg cttaccttga atatgaacct
6241 tgccccccct gttgctccaa atttccctgg tgaacaatta ctattcttca gatcttctgt
6301 gccatgttca ggaggttaca accaaggtat tatagattgc cttatccccc aagaatggat
6361 ccaacacttc taccaggaat cagcaccttc tcagtcagaa gtggccctaa tcaggtacgt
6421 caaccccgac acgggccgta cactgtttga ggcgaaattg cataggtcag gctatatcac
6481 tgtggctcat tctggagact atcctcttgt tgttccggct aatggatact ttagatttga
6541 ctcttgggta aatcagtttt actcactcgc cccaatggga actgggaatg ggcgaaggag
6601 ggctcagtaa tggctggagc tttcattgca ggattggcgg gtgacatgct cacgtcatcc
6661 gtgggctccc tggtgaacgc aggggcaaac gccatcaacc aaaagataga ctttgaaaac
6721 aacaaacaac tccagtctgc ttcctttcaa catgataaag agatgctcca agcgcaggtg
6781 aacgcaacca agcagctgca atctgagatg atagccctaa aacagggggt tctggccgca
6841 ggcggctttt cccccactga tgcagcgagg ggggccatcg gtgcgcccat gacaaaggtg
6901 cttgactggt ctggcactcg atactgggct cccaattcca caaagacaac tggttattcg
6961 gggcaattca cctcttcacc tgtgcacatg cctagcccga gtgtcccaca atcaaaaccc
7021 gcaaagccca agtctctagg ttcttcttct tcttctagta gtgtttacag tatgtctacc
7081 caattaactt ctctaacatc tggctcttct agtaatgctt cttctgcttc tacaaaattg
7141 acaaatttga gctccggctc ttctcaaaac agaacagcag agtgggtgaa ccaacaaaga
7201 agtctcagcc ctttcatgag tggcgcactc aatatctcgc atgtcacgcc accttcaagt
7261 agggcctcca gttctgggac ggtctcaacc gtgcccaagg aagttttgga ctcctggaca
7321 tctgcattca acacacacag acagccgctc ttcgcacacc tcagagtgag gggggagtca
7381 cgtgtttag
//