Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| PZ038592 | GII.17 | |
|
|---|---|---|---|
| GII.P17 |
ORF1: 1..2676
ORF2: 2657..4273
ORF3: 4273..5052
LOCUS PZ038592 5076 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Fairfield0109
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PZ038592
VERSION PZ038592.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 5076)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 5076)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..5076
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Fairfield0109"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="04-Sep-2024"
/note="genotype: GII.17[P17]"
gene <1..2676
/gene="ORF1"
CDS <1..2676
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39381.1"
/translation="FQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPED
KGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIRE
ERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERAT
LGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGF
WVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEG
APEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGT
TPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGA
PILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKP
FTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRK
NDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLW
GSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADY
SRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSG
VPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLT
AKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYW
TRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYV
PRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..201
/gene="ORF1"
/product="p22"
mat_peptide 202..600
/gene="ORF1"
/product="VPg"
mat_peptide 601..1143
/gene="ORF1"
/product="Pro"
mat_peptide 1144..2673
/gene="ORF1"
/product="RdRp"
gene 2657..4273
/gene="ORF2"
CDS 2657..4273
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39382.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRINFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 4273..5052
/gene="ORF3"
CDS 4273..5052
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39383.1"
/translation="MAGAFIAGLAGDMFTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 ttccaagagg ctatttactc tatactccaa attgctggtg cagccttcgt caccacacgc
61 atcgtgaggc gcatgaacat ctcaaacctc tggtcgaagc cacccgtcga agagggtgat
121 gagcctgaag acaaaggggg gtgccccaag cccagggatg aagatgacct cactattgac
181 tccaaagaca ttaaagcaga aggtaagaag ggcaagaaca aatctggccg gggcaagaaa
241 cacacagctt tctcatccaa gggcctcagt gatgaagagt acgatgagta caagagaatc
301 agggaggaga gaaatggcaa gtactcaata gaagaatacc tccaggatag ggatagatac
361 tatgaagagc ttgccattgc taaggccact gaggaagact tctgtgaaga ggaggaaatc
421 aaaattcgcc agagaatctt ccggcccacc aggaagcagc ggaaagagga aagagccacg
481 cttgggctcg tcacaggatc ggaaatcaga aagaggaacc cagatgattt taagccaaaa
541 ggaaaattgt gggctgatga caacaggagt gtggactaca atgagaggat agattttgag
601 gctcccccaa gtgtttggtc taggatagtc aactttggta caggatgggg attctgggtc
661 tccccaagtc tctttataac ttcaacacat gtcataccaa aaggaattac tgaggccttt
721 ggagttccca ttaaccaaat tcaaattcac aaatctggag agttttgccg cttgcggttt
781 ccaaaaccaa tcaggccaga cgtgagtgga atgatcttgg aagagggtgc ccccgaaggc
841 actgttgttt ccattctcat caagaggacg acaggggaac tgatgcctct cgcagtcaga
901 atgggaactc atgccacaat gaaaatccaa ggtagaacgg tgggcggtca aatgggcatg
961 cttctcactg gctcaaacgc caaaagcatg gacctaggca caacaccagg tgactgtggg
1021 tgcccataca tatacaaaag gggcaatgac ttcgtggtca ttggggtgca cactgcagca
1081 gcccgtggag gtaacacagt catatgtgcc acacagggga gtgaaggcga agccaccctc
1141 gaaggaggtg acaacaaggg cacctattgt ggagccccca tattgggtcc tggcaacgca
1201 ccaaaattga gcacaaaaac aaaattctgg agatcttcta acgcgccgct cccgccaggt
1261 acctacgaac cagcatacct tggtggaaaa gacccgcgag tgaagggagg cccatctcta
1321 caacaggtta tgagagacca actcaaacct tttacagagc ccagagggaa gccaccaaaa
1381 ccaagtgtcc tagagtcagc aaagaagacc atcattaatg ttctggaaca aaccattgac
1441 ccccctgaaa agtggtcata tgcccaagct tgtgcatccc tcgacaagac aacctccagt
1501 ggatacccgc atcacgtccg gaagaatgac tactggagtg gtgaatcctt cacggggaaa
1561 cttgcagacc aggcctcaaa agcaaatctc atgtatgagg aaggtaagca catgcaacca
1621 gtttacaccg cagcactcaa agacgagctc gtgaaaactg acaaaattta tggcaagatc
1681 aagaaaagac tcctgtgggg ctctgaccta tccaccatga ttcgatgcgc cagggcattt
1741 ggtggcctca tggacgagct caaagcaaat tgtatcacac tccctatcag agttggtatg
1801 aacatgaatg aagatggtcc cataatattt gaaaagcact ccaggtatag gtaccactat
1861 gatgctgatt actcccgctg ggattccaca caacagcggg cagtgctgga agcggcactt
1921 gaaatcatgg tgaggttttc tgctgagcca cagttggcac aaatagtggc agaggacctg
1981 ctatcaccaa gtgtggttga tgtgggcgat ttcaagatta ctattaatga aggcctacca
2041 tctggcgtgc cttgcacttc acaatggaat tctattgccc actggttact caccctatgt
2101 gccctgtctg aagtgacagg actaggccct gacatcatac aagccaactc catgtactct
2161 ttctatggtg atgatgagat tgtgagcaca gacataaaat tagacccaga gaaattgact
2221 gcaaaactca aagaatatgg tcttaaaccc acccggcctg acaagactga ggggccactg
2281 gtaattagtg aggacctgaa tgggttgact ttcctccgcc gaacagtcac ccgcgatcca
2341 gcgggttggt ttggaaagtt ggaccaaaac tccatcctca gacagctgta ctggacaagg
2401 ggacccaacc atgaagaccc cagtgagact atgataccac acgcacagag acctgtgcag
2461 ctcatggcat tgctaggaga atcctcccta catggaccct cattttacag caaggttagc
2521 aaactggtta tatctgaact taaagaggga ggaatggatt tttatgtgcc cagacaagag
2581 tcaatgttca ggtggatgag gttctcagat ctaagcacat gggagggcga tcgcaatctg
2641 gctcccagtt ttgtgaatga agatggcgtc gaatgacgcc gctccatcta atgatggtgc
2701 tgctggtctc gtaccagagg gcaataacga gacccttccc ctagaaccag ttgcgggcgc
2761 agcaatagcc gcacccgtca ccggccaaaa taatataatt gacccctgga ttagaataaa
2821 ttttgtgcaa gcaccaaatg gagagttcac agtgtcaccc agaaactctc ctggagaaat
2881 tttactaaac ctagagttgg gccctgatct gaacccttat ttggctcatt tgtcaaggat
2941 gtataatgga tatgctggtg gagttgaagt ccaggttctc ctggcaggga acgcgttcac
3001 tgccgggaag atcctcttcg ccgctgtccc gccaaatttt ccggtggaat tcttaagccc
3061 agcccagatt acaatgctcc cacatataat agtagatgtt aggactcttg aaccaattat
3121 gatcccatta cctgatgtta ggaatacatt tttccactat aataatcagc ccaacagccg
3181 catgagatta gtggctatgc tctacacccc ccttagatct aatggctcag gtgatgatgt
3241 tttcactgtt tcttgcaggg ttttgactag gcctactcct gattttgagt tcacttatct
3301 agtgccaccc tctgttgaat ctaagactaa acccttttct ttacccattc taaccctttc
3361 tgagctcaca aattcgaggt tcccggtccc catcgattcg cttttcaccg cccaaaataa
3421 tgtgttgcag gtgcagtgtc aaaatggcag gtgcacactt gacggtgagc tacaaggcac
3481 aacccaattg ctcccatctg gcatctgtgc gttcagggga cgggtgacag cagaaactga
3541 caatcctgac aagtggcaca tgcaactgca aaaccttaat ggcacaacat atgacccaac
3601 tgatgatgtg ccagccccac tgggtacacc tgacttcaag ggcgtcgtgt ttgggatggc
3661 aagccaaaga aatgtgggta acgacgcgcc cggctcaacc aggtcccatg aggcggtgat
3721 ttcaacctac agccccagat ttgttcctaa attaggctct gtcaatttca aaagcaatga
3781 cgatgatttc caattgcagc caacaagatt cacaccagtg ggcattaatg atgatggcaa
3841 ccaaccattc agacaatggg aattaccaga ttattcagga gtgcttacct tgaatatgaa
3901 ccttgccccc cctgttgctc caaatttccc tggcgaacaa ttactattct tcagatcttc
3961 tgtgccatgt tcaggaggtt acaaccaagg tattatagat tgccttatcc cccaagaatg
4021 gatccaacac ttctaccagg aatcagcacc ttctcagtca gaagtggccc taatcaggta
4081 cgtcaacccc gacacgggtc gtacactgtt tgaggcaaaa ttgcataggt caggctatat
4141 cactgtggct cattctggag actatcctct tgttgttccg gctaatggat actttagatt
4201 tgactcttgg gtaaatcagt tttactcact cgccccaatg ggaactggga atgggcgaag
4261 gagggctcag taatggctgg agctttcatt gcaggattgg cgggtgacat gttcacgtca
4321 tccgtgggct ccctggtgaa cgcaggggca aacgccatca accaaaagat agactttgaa
4381 aacaacaaac aactccagtc tgcttccttt caacatgata aagagatgct ccaagcgcag
4441 gtgaacgcaa ccaagcagct gcaatctgag atgatagccc taaaacaggg ggttttggcc
4501 gcaggcggct tttcccccac tgatgcagcg aggggggcca tcggtgcacc catgacaaag
4561 gtgcttgact ggtctggcac tcgatactgg gctcccaatt ccacaaagac aactggttat
4621 tcggggcaat tcacctcttc acctgtgcac atgcccagcc cgagtgtccc acaatcaaaa
4681 cccgcaaagc ccaagtctct aggttcttct tcttcttcta gtagtgttta cagtatgtct
4741 acccaattaa cttctctaac atctggctct tctagtaatg cttcttctgc ttctacaaaa
4801 ttgacaaatt tgagctccgg ctcttctcaa aacagaacag cagagtgggt gaaccaacag
4861 agaagtctca gccctttcat gagtggcgca ctcaatatct cgcatgtcac gccaccttca
4921 agtagggcct ccagttctgg gacggtctca accgtgccca aggaagtttt ggactcctgg
4981 acatctgcat tcaacacaca cagacaaccg ctcttcgcac acctcagagt gaggggggag
5041 tcacgtgttt agtgaaaaga aataattggc tataat
//