Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038591 | GII.17 | |
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| GII.P17 |
ORF1: 1..2991
ORF2: 2972..4588
ORF3: 4588..5365
LOCUS PZ038591 5365 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Washington0105
nonstructural polyprotein (ORF1) gene, partial cds; VP1 (ORF2)
gene, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION PZ038591
VERSION PZ038591.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 5365)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 5365)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..5365
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Washington0105"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="11-Jul-2024"
/note="genotype: GII.17[P17]"
gene <1..2991
/gene="ORF1"
CDS <1..2991
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39378.1"
/translation="NFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAI
KNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIRYY
VKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRDED
DLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEY
LQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRK
RNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITST
HVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILI
KRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIY
KRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKL
STKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKP
SVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTG
KLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTTIRCA
RAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAV
LEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNSIA
HWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPT
RPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSE
TMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMR
FSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..516
/gene="ORF1"
/product="p22"
mat_peptide 517..915
/gene="ORF1"
/product="VPg"
mat_peptide 916..1458
/gene="ORF1"
/product="Pro"
mat_peptide 1459..2988
/gene="ORF1"
/product="RdRp"
gene 2972..4588
/gene="ORF2"
CDS 2972..4588
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39379.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 4588..>5365
/gene="ORF3"
CDS 4588..>5365
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39380.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNTSSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 aatttcgacc gtaacaaagt cgccgccttc agacaattgg cagctgaaaa caaatacggt
61 cttatggaca cactgagggt cggcaaccaa ctgaaaagtg tcaaaaccct ggatgagctg
121 aagcaggcta taaagaacat caccattaag aagtgccaga tagtgtacaa tggatgcacc
181 tacaccatgg aatctgacgg gaggaacaag gttgtggttg aaaaggttca aaatgcaaca
241 gtccaaacca acaatgaact tgcaggagca ctccaccacc tgagatctgc aagaataagg
301 tattatgtca aatgcttcca agaagctatt tactctatac tccaaattgc tggtgcagcc
361 ttcgtcacca cacgcatcgt gaggcgcatg aacatctcaa acctctggtc gaagccgccc
421 gtcgaagagg gtgatgagcc tgaagacaaa ggggggtgtc ccaagcccag ggatgaagat
481 gacctcacta ttgactccaa agacattaaa gcagaaggta agaagggcaa gaacaaatct
541 ggccggggca agaaacacac agctttctca tccaagggcc tcagtgatga agagtacgat
601 gagtacaaga gaatcaggga ggagagaaat ggcaagtact caatagaaga atacctccag
661 gatagggata gatactatga agagcttgcc attgctaagg ccactgagga agacttctgt
721 gaagaggagg aaatcaaaat tcgccagaga atcttccggc ccaccaggaa gcagcggaaa
781 gaggaaagag ccacgcttgg gctcgtcaca ggatcggaaa ttagaaagag gaacccagat
841 gattttaagc caaaaggaaa attgtgggct gatgacaaca ggagtgtgga ctacaatgag
901 aggatagatt ttgaggctcc cccaagtgtt tggtctagga tagtcaactt tggtacagga
961 tggggattct gggtctcccc aagtctcttt ataacttcaa cacatgtcat accaaaagga
1021 atcactgagg cttttggagt tcccattaac cagattcaaa ttcacaaatc tggagagttt
1081 tgccgtttgc ggtttccaaa accaatcagg ccagacgtga gtggaatgat cttggaagag
1141 ggtgcccctg aaggcactgt tgtttccatt ctcatcaaga ggacgacagg ggaactgatg
1201 cctctcgcag ttagaatggg aactcatgcc acaatgaaaa tccaaggtag aacggtgggc
1261 ggtcaaatgg gcatgcttct cactggctca aacgccaaaa gcatggacct aggcacaaca
1321 ccaggtgact gtgggtgccc atacatatac aaaaggggca atgacttcgt ggtcattggg
1381 gtgcacactg cggcagcccg tggaggtaac acggtcatat gtgccacaca ggggagtgaa
1441 ggcgaagcca ccctcgaagg aggtgacaac aagggcacct attgtggagc ccccatcttg
1501 ggacctggca acgcaccaaa attgagcaca aaaacaaaat tctggagatc ttctaacgcg
1561 ccgctcccgc caggcaccta tgaaccagca taccttggtg gaaaagaccc gcgtgtgaag
1621 ggaggcccat ctctacaaca ggttatgaga gaccaactca aaccttttac agagcccaga
1681 gggaagccac caaagccaag tgtcctagaa tcagcaaaga agaccatcat taatgttctg
1741 gaacaaacca ttgacccccc tgaaaagtgg tcatatgccc aagcttgtgc atccctcgac
1801 aagacaacct ccagtggata cccgcatcac gtccggaaga atgattactg gagtggtgaa
1861 tccttcacgg ggaaacttgc agaccaggcc tcaaaagcaa atctcatgta tgaggaaggt
1921 aagcacatgc aaccagttta caccgcagca ctcaaagacg agctcgtgaa aactgacaaa
1981 atttatggca agatcaagaa gagactcctg tggggctctg acctatccac cacgattcga
2041 tgcgccaggg catttggtgg cctcatggat gagctcaaag caaattgtat cacactccct
2101 atcagagttg gtatgaacat gaatgaagat ggtcccataa tatttgaaaa gcactccagg
2161 tacaggtacc actatgatgc tgattattcc cgctgggatt ccacacaaca gcgggcagtg
2221 ctggaagcgg cacttgaaat catggtgaga ttttctgctg agccacagtt ggcacaaata
2281 gtggcagagg acctgctatc accaagtgtg gttgatgtgg gcgattttaa aattgctatt
2341 aatgaaggcc taccatctgg cgtgccttgc acttcacaat ggaattctat tgcccactgg
2401 ttactcaccc tatgtgccct gtctgaagtg acaggactag gccctgacat catacaagcc
2461 aactccatgt actctttcta tggtgatgat gagattgtga gcacagacat aaaattagac
2521 ccagagaaat tgactgcaaa actcaaagaa tatggtctta aacccacccg gcctgacaag
2581 actgaggggc cactggtgat tagtgaggac ctgaatgggt tgactttcct ccgccgaaca
2641 gtcacccgcg acccagcggg ttggtttgga aagttggatc aaaactccat cctcagacag
2701 ctgtactgga caaggggacc caaccatgaa gaccccagtg agactatgat accacacgca
2761 cagagacctg tgcagctcat ggcattgcta ggagaatcct ccctacatgg accctcattt
2821 tacagcaagg ttagcaagct ggttatatct gaacttaaag agggaggaat ggatttttat
2881 gtgcccagac aagagtcaat gttcaggtgg atgaggttct cagatctaag cacatgggag
2941 ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg acgccgctcc
3001 atctaatgat ggtgctgctg gtctcgtacc agagggcaat aacgagaccc ttcccctaga
3061 accagttgcg ggcgcagcca tagccgcacc cgtcactggc caaaataata taattgaccc
3121 ctggattaga acaaattttg tgcaagcacc aaatggagag ttcacagttt cacccagaaa
3181 ctctcctgga gaaattttac taaacctaga attgggccct gatctgaacc cttatttggc
3241 tcatttgtca aggatgtata atggatatgc tggtggagtt gaagtccagg ttctcctggc
3301 agggaacgcg ttcactgccg ggaagatcct cttcgccgct gtcccgccaa attttccagt
3361 ggaattctta agcccagccc agattacaat gctcccacat ataatagtag atgttaggac
3421 tcttgaacca attatgatcc cgttacctga tgttaggaat acattcttcc actataataa
3481 tcagcccaac agccgcatga gattagtggc tatgctctac acccccctta gatctaatgg
3541 ctcaggtgat gatgttttca ctgtttcttg cagggttttg actaggccta ctcctgattt
3601 tgagttcact tatctagtgc caccctctgt tgaatctaag actaaaccct tttctttacc
3661 cattctaacc ctttctgagc tcacaaattc gaggttcccg gtccccatcg attcgctttt
3721 caccgcccaa aataatgtgt tgcaggtgca atgtcaaaat ggcaggtgca cacttgacgg
3781 tgagctacaa ggcacaaccc agttgctccc atctggcatc tgtgcgttca ggggacgggt
3841 gacagcagaa actgacaatc ctgacaagtg gcacatgcaa ctgcaaaacc ttaatggcac
3901 aacatatgac ccgactgatg atgtgccagc cccattgggt acacctgact tcaagggcgt
3961 cgtgtttggg atggcaagcc aaagaaatgt gggtaacgac gcgcccggtt caaccaggtc
4021 ccatgaggcg gtgatttcaa cctacagccc cagatttgtt cctaaattag gctctgtcaa
4081 tttcaaaagc aatgacgatg atttccaatt gcagccaaca agattcacac cagtgggcat
4141 taatgatgat ggcaaccaac cattcagaca atgggaatta ccagattatt caggggtgct
4201 cactttgaat atgaaccttg cccccccggt tgctccaaat ttccctggcg aacaattact
4261 attcttcaga tcttctgtgc catgttcagg aggttacaac caaggtatta tagattgcct
4321 tatcccccaa gaatggatcc aacacttcta ccaggaatca gcaccttctc agtcagaagt
4381 ggccctaatc aggtacgtca accccgacac gggtcgcaca ctgtttgagg caaaattgca
4441 taggtcaggc tatatcactg tggctcactc tggagactat cctcttgttg ttccggctaa
4501 tggatacttt agatttgact cttgggtaaa tcagttttac tcactcgccc caatgggaac
4561 tgggaatggg cgaaggaggg ctcagtaatg gctggagctt tcattgcagg attggcgggt
4621 gacatgctca cgtcatccgt gggctccctg gtgaacgcag gggcaaacgc catcaaccaa
4681 aagatagact ttgaaaacaa caaacaactc cagtctgctt cctttcaaca tgataaagag
4741 atgctccaag cgcaggtgaa cgcaaccaag cagctgcaat ctgagatgat agccctaaaa
4801 cagggggttt tggccgcagg cggcttttcc cccactgatg cagcgagggg ggccatcggt
4861 gcacccatga caaaggtgct tgactggtct ggcactcgat actgggctcc caattccaca
4921 aagacaactg gttattcggg gcaattcacc tcctcacctg tgcacatgcc cagcccgagt
4981 gccccacaat caaaacccgc aaagcccaag tctctaggtt cttcttcttc ttctagtagt
5041 gtttacagta tgtctaccca attaacttct ctaacatctg gctcttctag taatacttct
5101 tctgcttcta caaaattgac aaatttaagc tccggctctt ctcaaaacag aacagcagag
5161 tgggtgaacc aacagagaag tctcagccct ttcatgagtg gcgcactcaa tatctcgcac
5221 gtcacgccac cttcgagtag ggcctccagt tctgggacgg tctcaaccgt gcccaaggaa
5281 gttttggact cctggacatc tgcattcaac acacgcagac agccgctctt cgcacacctc
5341 agagtgaggg gggagtcacg tgttt
//