Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038589 | GII.17 | |
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| GII.P17 |
ORF1: 1..2253
ORF2: 2234..3850
ORF3: 3850..4629
LOCUS PZ038589 4653 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Providence0102
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PZ038589
VERSION PZ038589.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 4653)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 4653)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..4653
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Providence0102"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="09-May-2024"
/note="genotype: GII.17[P17]"
gene <1..2253
/gene="ORF1"
CDS <1..2253
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39372.1"
/translation="IRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWA
DDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVP
INQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRM
GTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTA
AARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPL
PPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVL
EQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYE
EGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANC
ITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAE
PQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTG
LGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISED
LNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMA
LLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLA
PSFVNEDGVE"
mat_peptide <1..177
/gene="ORF1"
/product="VPg"
mat_peptide 178..720
/gene="ORF1"
/product="Pro"
mat_peptide 721..2250
/gene="ORF1"
/product="RdRp"
gene 2234..3850
/gene="ORF2"
CDS 2234..3850
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39373.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGCAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 3850..4629
/gene="ORF3"
CDS 3850..4629
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39374.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 attcgccaga gaatcttccg gcccaccagg aagcagcgga aagaggaaag agccacgctt
61 gggctcgtca caggatcgga aattagaaag aggaacccag atgattttaa gccaaaagga
121 aaattgtggg ctgatgacaa caggagtgtg gactacaatg agaggataga ttttgaggct
181 cccccaagtg tttggtctag gatagtcaac tttggtacag gatggggatt ctgggtctcc
241 ccaagtctct ttataacttc aacacatgtc ataccaaaag gaatcactga ggcttttgga
301 gttcccatta accagattca aattcacaaa tctggagagt tttgccgttt gcggtttcca
361 aaaccaatca ggccagacgt gagtggaatg atcttggaag agggtgcccc tgaaggcact
421 gttgtttcca ttctcatcaa gaggacgaca ggggaactga tgcctctcgc agttagaatg
481 ggaactcatg ccacaatgaa aatccaaggt agaacggtgg gcggtcaaat gggcatgctt
541 ctcactggct caaacgccaa aagcatggac ctaggcacaa caccaggtga ctgtgggtgc
601 ccatacatat acaaaagggg caatgacttc gtggtcattg gggtgcacac tgcggcagcc
661 cgtggaggta acacggtcat atgtgccaca caggggagtg aaggcgaagc caccctcgaa
721 ggaggtgaca acaagggcac ctattgtgga gcccccatct tgggacctgg caacgcacca
781 aaattgagca caaaaacaaa attctggaga tcttctaacg cgccgctccc gccaggcacc
841 tatgaaccag cataccttgg tggaaaagac ccgcgtgtga agggaggccc atctctacaa
901 caggttatga gagaccaact caaacctttt acagagccca gagggaagcc accaaagcca
961 agtgtcctag aatcagcaaa gaagaccatc attaatgttc tggaacaaac cattgacccc
1021 cctgaaaagt ggtcatatgc ccaagcttgt gcatccctcg acaagacaac ctccagtgga
1081 tacccgcatc acgtccggaa gaatgattac tggagtggtg aatccttcac ggggaaactt
1141 gcagaccagg cctcaaaagc aaatctcatg tatgaggaag gtaagcacat gcaaccagtt
1201 tacaccgcag cactcaaaga cgagctcgtg aaaactgaca aaatttatgg caagatcaag
1261 aaaagactcc tgtggggctc tgacctatcc accatgattc gatgcgccag ggcatttggt
1321 ggcctcatgg atgagctcaa agcaaattgt atcacactcc ctatcagagt tggtatgaac
1381 atgaatgaag atggtcccat aatatttgaa aagcactcca ggtacaggta ccactatgat
1441 gctgattatt cccgctggga ttccacacaa cagcgggcag tgctggaagc ggcacttgaa
1501 atcatggtga gattttctgc tgagccacag ttggcacaaa tagtggcaga ggacctgcta
1561 tcaccaagtg tggttgatgt gggcgatttc aaaattgcta ttaatgaagg cctaccatct
1621 ggcgtgcctt gcacttcaca atggaattct attgcccact ggttactcac cctatgtgcc
1681 ctgtctgaag tgacaggact aggccctgac atcatacaag ccaactccat gtactctttc
1741 tatggtgatg atgagattgt gagcacagac ataaaattag acccagagaa attgactgca
1801 aaactcaaag aatatggtct taaacccacc cggcctgaca agactgaggg gccactggtg
1861 attagtgagg acctgaatgg gttgactttc ctccgccgaa cagtcacccg cgacccagcg
1921 ggttggtttg gaaagttgga tcaaaactcc atcctcagac agctgtactg gacaagggga
1981 cccaaccatg aagaccccag tgagactatg ataccacacg cacagagacc tgtgcagctc
2041 atggcattgc taggagaatc ctccctacat ggaccctcat tttacagcaa ggttagcaag
2101 ctggttatat ctgaacttaa agagggagga atggattttt atgtgcccag acaagagtca
2161 atgttcaggt ggatgaggtt ctcagatcta agcacatggg agggcgatcg caatctggct
2221 cccagttttg tgaatgaaga tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc
2281 tggtctcgta ccagagggca ataacgagac ccttccccta gaaccagttg cgggcgcagc
2341 catagccgca cccgtcactg gccaaaataa tataattgac ccctggatta gaacaaattt
2401 tgtgcaagca ccaaatggag agttcacagt gtcacccaga aactctcctg gagaaatttt
2461 actaaaccta gaattgggcc ctgatctgaa cccttatttg gctcatttgt caaggatgta
2521 taatggatgt gctggtggag ttgaagtcca ggttctcctg gcagggaacg cgttcactgc
2581 cgggaagatc ctcttcgccg ctgtcccgcc aaattttcca gtggaattct taagcccagc
2641 ccagattaca atgctcccac atataatagt agatgttagg actcttgaac caattatgat
2701 cccgttacct gatgttagga atacattctt ccactataat aatcagccca acagccgcat
2761 gagattagtg gctatgctct acacccccct tagatctaat ggctcaggtg atgatgtttt
2821 cactgtttct tgcagggttt tgactaggcc tactcctgat tttgagttca cttatctagt
2881 gccaccctct gttgaatcta agactaaacc cttttcttta cccattctaa ccctttctga
2941 gctcacaaat tcgaggttcc cggtccccat cgattcgctt ttcaccgccc aaaataatgt
3001 gttgcaggtg caatgtcaaa atggcaggtg cacacttgac ggtgagctac aaggcacaac
3061 ccagttgctc ccatctggca tctgtgcgtt caggggacgg gtgacagcag aaactgacaa
3121 tcctgacaag tggcacatgc aactgcaaaa ccttaatggc acaacatatg acccgactga
3181 tgatgtgcca gccccattgg gtacacctga cttcaagggc gtcgtgtttg ggatggcaag
3241 ccaaagaaat gtgggtaacg acgcgcccgg ttcaaccagg tcccatgagg cggtgatttc
3301 aacctacagc cccagatttg ttcctaaatt aggctctgtc aatttcaaaa gcaatgacga
3361 tgatttccaa ttgcagccaa caagattcac accagtgggc attaatgatg atggcaacca
3421 accattcaga caatgggaat taccagatta ttcaggggtg cttactttga atatgaacct
3481 tgcccccccg gttgctccaa atttccctgg cgaacaatta ctattcttca gatcttctgt
3541 gccatgttca ggaggttaca accaaggtat tatagattgc cttatccccc aagaatggat
3601 ccaacacttc taccaggaat cagcaccttc tcagtcagaa gtggccctaa tcaggtacgt
3661 caaccccgac acgggtcgca cactgtttga ggcaaaattg cataggtcag gctatatcac
3721 tgtggctcac tctggagact atcctcttgt tgttccggct aatggatact ttagatttga
3781 ctcttgggta aatcagtttt actcactcgc cccaatggga actgggaatg ggcgaaggag
3841 ggctcagtaa tggctggagc tttcattgca ggattggcgg gtgacatgct cacgtcatcc
3901 gtgggctccc tggtgaacgc aggggcaaac gccatcaacc aaaagataga ctttgaaaac
3961 aacaaacaac tccagtctgc ttcctttcaa catgataaag agatgctcca agcgcaggtg
4021 aacgcaacca agcagctgca atctgagatg atagccctaa aacagggggt tttggccgca
4081 ggcggctttt cccccactga tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg
4141 cttgactggt ctggcactcg atactgggct cccaattcca caaagacaac tggttattcg
4201 gggcaattca cctcctcacc tgtgcacatg cccagcccga gtgccccaca atcaaaaccc
4261 gcaaagccca agtctctagg ttcttcttct tcttctagta gtgtttacag tatgtctacc
4321 caattaactt ctctaacatc tggctcttct agtaatgctt cttctgcttc tacaaaattg
4381 acaaatttaa gctccggctc ttctcaaaac agaacagcag agtgggtgaa ccaacagaga
4441 agtctcagcc ctttcatgag tggcgcactc aatatctcgc acgtcacgcc accttcgagt
4501 agggcctcca gttctgggac ggtctcaacc gtgcccaagg aagttttgga ctcctggaca
4561 tctgcattca acacacgcag acagccgctc ttcgcacacc tcagagtgag gggggagtca
4621 cgtgtttagt gaaaagaaat aattggctat aat
//