Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038588 | GII.17 | |
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| GII.P17 |
ORF1: 1..2142
ORF2: 2123..3739
ORF3: 3739..4518
LOCUS PZ038588 4542 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Providence0101
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PZ038588
VERSION PZ038588.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 4542)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 4542)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..4542
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Providence0101"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="26-Apr-2024"
/note="genotype: GII.17[P17]"
gene <1..2142
/gene="ORF1"
CDS <1..2142
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39369.1"
/translation="PKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSP
SLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEG
TVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGP
NHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQE
SMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..66
/gene="ORF1"
/product="VPg"
mat_peptide 67..609
/gene="ORF1"
/product="Pro"
mat_peptide 610..2139
/gene="ORF1"
/product="RdRp"
gene 2123..3739
/gene="ORF2"
CDS 2123..3739
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39370.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 3739..4518
/gene="ORF3"
CDS 3739..4518
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39371.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ccaaaaggaa aattgtgggc tgatgacaac aggagtgtgg actacaatga gaggatagat
61 tttgaggctc ccccaagtgt ttggtctagg atagtcaact ttggtacagg atggggattc
121 tgggtctccc caagtctctt tataacttca acacatgtca taccaaaagg aatcactgag
181 gcttttggag ttcccattaa ccagattcaa attcacaaat ctggagagtt ttgccgtttg
241 cggtttccaa aaccaatcag gccagacgtg agtggaatga tcttggaaga gggtgcccct
301 gaaggcactg ttgtttccat tctcatcaag aggacgacag gggaactgat gcctctcgca
361 gttagaatgg gaactcatgc cacaatgaaa atccaaggta gaacggtggg cggtcaaatg
421 ggcatgcttc tcactggctc aaacgccaaa agcatggacc taggcacaac accaggtgac
481 tgtgggtgcc catacatata caaaaggggc aatgacttcg tggtcattgg ggtgcacact
541 gcggcagccc gtggaggtaa cacggtcata tgtgccacac aggggagtga aggcgaagcc
601 accctcgaag gaggtgacaa caagggcacc tattgtggag cccccatctt gggacctggc
661 aacgcaccaa aattgagcac aaaaacaaaa ttctggagat cttctaacgc gccgctcccg
721 ccaggcacct atgaaccagc ataccttggt ggaaaagacc cgcgtgtgaa gggaggccca
781 tctctacaac aggttatgag agaccaactc aaacctttta cagagcccag agggaagcca
841 ccaaagccaa gtgtcctaga atcagcaaag aagaccatca ttaatgttct ggaacaaacc
901 attgaccccc ctgaaaagtg gtcatatgcc caagcttgtg catccctcga caagacaacc
961 tccagtggat acccgcatca cgtccggaag aatgattact ggagtggtga atccttcacg
1021 gggaaacttg cagaccaggc ctcaaaagca aatctcatgt atgaggaagg taagcacatg
1081 caaccagttt acaccgcagc actcaaagac gagctcgtga aaactgacaa aatttatggc
1141 aagatcaaga aaagactcct gtggggctct gacctatcca ccatgattcg atgcgccagg
1201 gcatttggtg gcctcatgga tgagctcaaa gcaaattgta tcacactccc tatcagagtt
1261 ggtatgaaca tgaatgaaga tggtcccata atatttgaaa agcactccag gtacaggtac
1321 cactatgatg ctgattattc ccgctgggat tccacacaac agcgggcagt gctggaagcg
1381 gcacttgaaa tcatggtgag attttctgct gagccacagt tggcacaaat agtggcagag
1441 gacctgctat caccaagtgt ggttgatgtg ggcgatttca aaattgctat taatgaaggc
1501 ctaccatctg gcgtgccttg cacttcacaa tggaattcta ttgcccactg gttactcacc
1561 ctatgtgccc tgtctgaagt gacaggacta ggccctgaca tcatacaagc caactccatg
1621 tactctttct atggtgatga tgagattgtg agcacagaca taaaattaga cccagagaaa
1681 ttgactgcaa aactcaaaga atatggtctt aaacccaccc ggcctgacaa gactgagggg
1741 ccactggtga ttagtgagga cctgaatggg ttgactttcc tccgccgaac agtcacccgc
1801 gacccagcgg gttggtttgg aaagttggat caaaactcca tcctcagaca gctgtactgg
1861 acaaggggac ccaaccatga agaccccagt gagactatga taccacacgc acagagacct
1921 gtgcagctca tggcattgct aggagaatcc tccctacatg gaccctcatt ttacagcaag
1981 gttagcaagc tggttatatc tgaacttaaa gagggaggaa tggattttta tgtgcccaga
2041 caagagtcaa tgttcaggtg gatgaggttc tcagatctaa gcacatggga gggcgatcgc
2101 aatctggctc ccagttttgt gaatgaagat ggcgtcgaat gacgccgctc catctaatga
2161 tggtgctgct ggtctcgtac cagagggcaa taacgagacc cttcccctag aaccagttgc
2221 gggcgcagcc atagccgcac ccgtcactgg ccaaaataat ataattgacc cctggattag
2281 aacaaatttt gtgcaagcac caaatggaga gttcacagtg tcacccagaa actctcctgg
2341 agaaatttta ctaaacctag aattgggccc tgatctgaac ccttatttgg ctcatttgtc
2401 aaggatgtat aatggatatg ctggtggagt tgaagtccag gttctcctgg cagggaacgc
2461 gttcactgcc gggaagatcc tcttcgccgc tgtcccgcca aattttccag tggaattctt
2521 aagcccagcc cagattacaa tgctcccaca tataatagta gatgttagga ctcttgaacc
2581 aattatgatc ccgttacctg atgttaggaa tacattcttc cactataata atcagcccaa
2641 cagccgcatg agattagtgg ctatgctcta cacccccctt agatctaatg gctcaggtga
2701 tgatgttttc actgtttctt gcagggtttt gactaggcct actcctgatt ttgagttcac
2761 ctatctagtg ccaccctctg ttgaatctaa gactaaaccc ttttctttac ccattctaac
2821 cctttctgag ctcacaaatt cgaggttccc ggtccccatc gattcgcttt tcaccgccca
2881 aaataatgtg ttgcaggtgc aatgtcaaaa tggcaggtgc acacttgacg gtgagctaca
2941 aggcacaacc cagttgctcc catctggcat ctgtgcgttc aggggacggg tgacagcaga
3001 aactgacaat cctgacaagt ggcacatgca actgcaaaac cttaatggca caacatatga
3061 cccgactgat gatgtgccag ccccattggg tacacctgac ttcaagggcg tcgtgtttgg
3121 gatggcaagc caaagaaatg tgggtaacga cgcgcccggt tcaaccaggt cccatgaggc
3181 ggtgatttca acctacagcc ccagatttgt tcctaaatta ggctctgtca atttcaaaag
3241 caatgacgat gatttccaat tgcagccaac aagattcaca ccagtgggca ttaatgatga
3301 tggcaaccaa ccattcagac aatgggaatt accagattat tcaggggtgc ttactttgaa
3361 tatgaacctt gcccccccgg ttgctccaaa tttccctggc gaacaattac tattattcag
3421 atcttctgtg ccatgttcag gaggttacaa ccaaggtatt atagattgcc ttatccccca
3481 agaatggatc caacacttct accaggaatc agcaccttct cagtcagaag tggccctaat
3541 caggtacgtc aaccccgaca cgggtcgcac actgtttgag gcaaaattgc ataggtcagg
3601 ctatatcact gtggctcact ctggagacta tcctcttgtt gttccggcta atggatactt
3661 tagatttgac tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa ctgggaatgg
3721 gcgaaggagg gctcagtaat ggctggagct ttcattgcag gattggcggg tgacatgctc
3781 acgtcatccg tgggctccct ggtgaacgca ggggcaaacg ccatcaacca aaagatagac
3841 tttgaaaaca acaaacaact ccagtctgct tcctttcaac atgataaaga gatgctccaa
3901 gcgcaggtga acgcaaccaa gcagctgcaa tctgagatga tagccctaaa acagggggtt
3961 ttggccgcag gcggcttttc ccccactgat gcagcgaggg gggccatcgg tgcacccatg
4021 acaaaggtgc ttgactggtc tggcactcga tactgggctc ccaattccac aaagacaact
4081 ggttattcgg ggcaattcac ctcctcacct gtgcacatgc ccagcccgag tgtcccacaa
4141 tcaaaacccg caaagcccaa gtctctaggt tcttcttctt cttctagtag tgtttacagt
4201 atgtctaccc aattaacttc tctaacatct ggctcttcta gtaatgcttc ttctgcttct
4261 acaaaattga caaatttaag ctccggctct tctcaaaaca gaacagcaga gtgggtgaac
4321 caacagagaa gtctcagccc tttcatgagt ggcgcactca atatctcgca cgtcacgcca
4381 ccttcgagta gggcctccag ttctgggacg gtctcaaccg tgcccaagga agttttggac
4441 tcctggacat ctgcattcaa cacacgcaga cagccgctct tcgcacacct cagagtgagg
4501 ggggagtcac gtgtttagtg aaaagaaata attggctata at
//