Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038585 | GII.17 | |
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| GII.P17 |
ORF1: 1..4302
ORF2: 4283..5899
ORF3: 5899..6678
LOCUS PZ038585 6702 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Kent0097 nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PZ038585
VERSION PZ038585.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 6702)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 6702)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6702
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Kent0097"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="04-Apr-2024"
/note="genotype: GII.17[P17]"
gene <1..4302
/gene="ORF1"
CDS <1..4302
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39360.1"
/translation="TRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVL
WTPPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATT
LRACKDLGSYGLEILKLVMKWFFPKKEEANELALVRAIEDAVLDLEAIENNHMTTLLK
DKDALATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSS
RQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVV
LWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLD
YVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFD
KSGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQL
AAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKV
VVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRR
MNISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHT
AFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEI
KIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERID
FEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFC
RLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTV
GGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQ
GSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGK
DPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYA
QACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAAL
KDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNE
DGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLS
PSVVDVGDFKIAINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYS
FYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTR
DPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFY
SKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..192
/gene="ORF1"
/product="p48"
mat_peptide 193..1290
/gene="ORF1"
/product="NTPase"
mat_peptide 1291..1827
/gene="ORF1"
/product="p22"
mat_peptide 1828..2226
/gene="ORF1"
/product="VPg"
mat_peptide 2227..2769
/gene="ORF1"
/product="Pro"
mat_peptide 2770..4299
/gene="ORF1"
/product="RdRp"
gene 4283..5899
/gene="ORF2"
CDS 4283..5899
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39361.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNSDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 5899..6678
/gene="ORF3"
CDS 5899..6678
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39362.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQEVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 actaggccca tcaaagatgt cattggaaag cttaaaccac taaacattat gaacatactg
61 gcaacttgtg attggacttt tgcgggcata gtggaatcca tgatccttct tgctgaactc
121 tttggggtgc tctggacgcc cccagatgtg tctgcaataa ttgctccctt actcggtgac
181 tacgagatgc aaggccccga agatctggcc gtggaacttg tgcccgtggt aatgggagga
241 ataggtttgg tgttaggatt caccaaggaa aagatcggca agatgctttc atcagctgca
301 accacactca gggcctgtaa ggatctagga tcttatgggt tggagatact caaactggtc
361 atgaagtggt tcttccccaa gaaggaggag gccaacgagt tagccttggt aagggccatt
421 gaggatgcag ttctggattt ggaggcaata gaaaacaacc acatgaccac tctccttaag
481 gacaaagacg ccctggccac atacatgagg actcttgact tggaagaaga aaaagcaagg
541 aaactgtctt ccaaatcggc gtcacctgac atcgtgggca cagtaaacgc attattggca
601 agaatagcag ccgccaggtc actggtccac aaggctaagg aggagctctc gagcagacag
661 agacctgttg ttgtaatgat atcaggtagg ccaggtatag gaaagaccca tctggccaga
721 gagctagcca agaaggttgc gtcaacactg tcaggcgacc aaaggattgg actgataccc
781 agaaatggcg tcgaccattg ggacgcctac aaaggagagc gggtggttct gtgggatgac
841 tatggcatga gcaaccctat acaggacgca ctgaggctcc aagaattggc tgacacctgt
901 cctctgaccc taaattgtga cagaattgaa aacaaaggaa aagtgttcga cagtgacgcc
961 ataatcataa caaccaacct tgcaaaccca gcaccattgg attatgtcaa ctttgaggct
1021 tgttccagac gcatagactt cttggtgtat gcagacgcac ctgacatcga gaaggccaag
1081 cgtgacttcc ctggccaacc agatatgtgg aaagaccatt acagaccaga cttctcacac
1141 attaaacttc agctcgcacc acaaggaggc tttgataaga gtggcaacac cccacatggc
1201 aaaggtgtgg ttaagtctct gacgattggt tctctgatcg ccagggcttc tggcttgctc
1261 catgagagaa tggatgaatt cgagctccaa ggccccaact taccaacctt caatttcgac
1321 cgtaacaaag tcgccgcctt cagacaattg gcagctgaaa acaaatacgg tcttatggac
1381 acactgaggg tcggcaacca actgaaaagt gtcaaaaccc tggatgagct gaagcaggct
1441 ataaagaaca tcaccatcaa gaagtgccag atagtgtaca atggatgcac ctacaccatg
1501 gaatctgacg ggaggaacaa ggttgtggtt gaaaaggttc aaaatgcaac agtccaaacc
1561 aacaatgaac ttgcaggagc actccaccac ctgagatctg caagaataag gtattatgtc
1621 aaatgcttcc aagaagctat ttactctata ctccaaattg ctggtgcagc cttcgtcacc
1681 acacgcatcg tgaggcgcat gaacatctca aacctctggt cgaagccacc cgtcgaagag
1741 ggtgacgagc ctgaagacaa aggggggtgt cccaagccca gggatgaaga tgacctcact
1801 attgactcca aagacattaa agcagaaggt aagaagggca agaacaaatc tggccggggc
1861 aagaaacaca cagctttctc atccaagggc ctcagtgatg aagagtacga tgagtacaag
1921 agaatcaggg aggagagaaa tggcaagtac tcaatagaag aatacctcca ggatagggat
1981 agatactatg aagagcttgc cattgctaag gccactgagg aagacttctg tgaagaggag
2041 gaaatcaaaa ttcgccagag aatcttccgg cccaccagga agcagcggaa agaggaaaga
2101 gccacgcttg ggctcgtcac aggatcggaa attagaaaga ggaacccaga tgattttaag
2161 ccaaaaggaa aattgtgggc tgatgacaac aggagtgtgg actacaatga gaggatagat
2221 tttgaggctc ccccaagtgt ttggtctagg atagtcaact ttggtacagg atggggattc
2281 tgggtctccc caagtctctt tataacttca acacatgtca taccaaaagg aatcactgag
2341 gcttttggag ttcccattaa ccaaattcaa attcacaaat ctggagagtt ttgccgtttg
2401 cggtttccaa aaccaatcag gccagacgtg agtggaatga tcttggaaga gggtgcccct
2461 gaaggcactg ttgtttccat tctcatcaag aggacgacag gggaactgat gcctctcgca
2521 gttagaatgg gaactcatgc cacaatgaaa atccaaggta gaacggtggg cggtcaaatg
2581 ggcatgcttc tcactggctc aaacgccaaa agcatggacc taggcacaac accaggtgac
2641 tgtgggtgcc catacatata caaaaggggc aatgacttcg tggtcattgg ggtacacact
2701 gcggcagccc gtggaggtaa cacggtcata tgtgccacac aggggagtga aggcgaagcc
2761 accctcgaag gaggtgacaa caagggcacc tattgtggag cccccatctt gggacctggc
2821 aacgcaccaa aactgagcac aaaaacaaaa ttctggagat cttctaacgc gccgctcccg
2881 ccaggcacct atgaaccagc ataccttggt ggaaaagacc cgcgtgtgaa gggaggccca
2941 tctctacaac aggttatgag agaccaactc aaacctttta cagagcccag agggaagcca
3001 ccaaagccaa gtgtcctaga atcagcaaag aagaccatca ttaatgttct ggaacaaacc
3061 attgaccccc ctgaaaagtg gtcatatgcc caagcttgtg catccctcga caagacaacc
3121 tccagtggat acccgcatca cgtccggaag aatgattact ggagtggtga atccttcacg
3181 gggaaacttg cagaccaggc ctcaaaagca aatctcatgt atgaggaagg taagcacatg
3241 caaccagttt acaccgcagc actcaaagac gagctcgtga aaactgacaa aatttatggc
3301 aagatcaaga aaagactcct gtggggctct gacctatcca ccatgattcg atgcgccagg
3361 gcatttggtg gcctcatgga tgagctcaaa gcaaattgta tcacactccc tatcagagtt
3421 ggtatgaaca tgaatgaaga tggtcccata atatttgaaa agcactccag gtacaggtac
3481 cactatgatg ctgattattc ccgctgggat tccacacaac agcgggcagt gctggaagcg
3541 gcacttgaaa tcatggtgag attttctgct gagccacagt tggcacaaat agtggcagag
3601 gacctgctat caccaagtgt ggttgatgtg ggcgatttca aaattgctat caatgaaggc
3661 ctaccatctg gcgtgccttg cacttcacaa tggaattcta ttgcccactg gttactcacc
3721 ctatgtgccc tgtctgaagt gacaggacta ggccctgaca tcatacaagc caactccatg
3781 tactctttct atggtgatga tgagattgtg agcacagaca taaaattaga cccagagaaa
3841 ttgactgcaa aactcaaaga atatggtctt aaacccaccc ggcctgacaa gactgagggg
3901 ccactggtga ttagtgagga cctgaatggg ttgactttcc tccgccgaac agtcacccgc
3961 gatccagcgg gttggtttgg aaagttggat caaaactcca tcctcagaca gctgtactgg
4021 acaaggggac ccaaccatga agaccccagt gagactatga taccacacgc acagagacct
4081 gtgcagctca tggcattgct aggagaatcc tccctacatg gaccctcatt ttacagcaaa
4141 gttagcaagc tggttatatc tgaacttaaa gagggaggaa tggattttta tgtgcccaga
4201 caagagtcaa tgttcaggtg gatgaggttc tcagatctaa gcacatggga gggcgatcgc
4261 aatctggctc ccagttttgt gaatgaagat ggcgtcgaat gacgccgctc catctaatga
4321 tggtgctgct ggtctcgtac cagagggcaa taacgagacc cttcccctag aaccagttgc
4381 gggcgcagcc atagccgcac ccgtcactgg ccaaaataat ataattgacc cctggattag
4441 aacaaatttt gtgcaagcac caaatggaga gttcacagtg tcacccagaa actctcctgg
4501 agaaatttta ctaaacctag aattgggccc tgatctgaac ccttatttgg ctcatttgtc
4561 aaggatgtat aatggatatg ctggtggagt tgaagtccag gttctcctgg cagggaacgc
4621 gttcactgcc gggaagatcc tcttcgccgc tgtcccgcca aattttccag tggaattctt
4681 aagcccagcc cagattacaa tgctcccaca tataatagta gatgttagga ctcttgaacc
4741 aattatgatc ccgttacctg atgttaggaa tacattcttc cactataata atcagcccaa
4801 cagccgcatg agattagtgg ctatgctcta cacccccctt agatctaatg gctcaggtga
4861 tgatgttttc actgtttctt gcagggtttt gactaggcct actcctgatt ttgagttcac
4921 ttatctagtg ccaccctctg ttgaatctaa gactaaaccc ttttctttac ccattctaac
4981 cctctctgag ctcacaaatt cgaggttccc ggtccccatc gattcgcttt tcaccgccca
5041 aaataatgtg ttgcaggtgc aatgtcaaaa tggcaggtgc acacttgacg gtgagctaca
5101 aggcacaacc cagttgctcc catctggcat ctgtgcgttc aggggacggg taacagcaga
5161 aactgacaat tctgacaagt ggcacatgca actgcaaaac cttaatggca caacatatga
5221 cccgactgat gatgtgccag ccccattggg tacacctgac ttcaagggcg tcgtgtttgg
5281 gatggcaagc caaagaaatg tgggtaacga cgcgcccggt tcaaccaggt cccatgaggc
5341 ggtgatttca acctacagcc ccagatttgt tcctaaatta ggctctgtca atttcaaaag
5401 caatgacgat gatttccaat tgcagccaac aagattcaca ccagtgggca ttaatgatga
5461 tggcaaccaa ccattcagac aatgggaatt accagattat tcaggggtgc ttaccttgaa
5521 tatgaacctt gcccccccgg ttgctccaaa tttccctggc gaacaattac tattcttcag
5581 atcttctgtg ccatgttcag gaggttacaa ccaaggtatt atagattgcc ttatccccca
5641 ggaatggatc caacacttct accaggaatc agcaccttct cagtcagaag tggccctaat
5701 caggtacgtc aaccccgaca cgggtcgcac actgtttgag gcaaaattgc ataggtcagg
5761 ctatatcact gtggctcact ctggagacta tcctcttgtt gttccggcta atggatactt
5821 tagatttgac tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa ctgggaatgg
5881 gcgaaggagg gctcagtaat ggctggagct ttcattgcag gattggcggg tgacatgctc
5941 acgtcatccg tgggctccct ggtgaacgca ggggcaaacg ccatcaacca aaagatagac
6001 tttgaaaaca acaaacaact ccagtctgct tcctttcaac atgataaaga gatgctccaa
6061 gcgcaggtga acgcaaccaa gcagctgcaa tctgagatga tagccctaaa gcaggaggtt
6121 ttggccgcag gcggcttttc ccccactgat gcagcgaggg gggccatcgg tgcacccatg
6181 acaaaggtgc ttgactggtc tggcactcga tactgggctc ccaattccac aaagacaact
6241 ggttattcgg ggcaattcac ctcctcacct gtgcacatgc ccagcccgag tgtcccacaa
6301 tcaaaacccg caaagcccaa gtctctaggt tcttcttctt cttctagtag tgtttacagt
6361 atgtctaccc aattaacttc tctaacatct ggctcttcta gtaatgcttc ttctgcttct
6421 acaaaattga caaatttaag ctccggctct tctcaaaaca gaacagcaga gtgggtgaac
6481 caacagagaa gtctcagccc tttcatgagt ggcgcactca atatctcgca cgtcacgcca
6541 ccttcgagta gggcctccag ttctgggacg gtctcaaccg tgcccaagga agttttggac
6601 tcctggacat ctgcattcaa cacacgcaga cagccgctct tcgcacacct cagagtgagg
6661 ggggagtcac gtgtttagtg aaaagaaata attggctata at
//