Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038584 | GII.17 | |
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| GII.P17 |
ORF1: 1..2865
ORF2: 2846..4462
ORF3: 4462..4989
LOCUS PZ038584 4989 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Kent0096 nonstructural
polyprotein (ORF1) gene, partial cds; VP1 (ORF2) gene, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION PZ038584
VERSION PZ038584.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 4989)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 4989)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..4989
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Kent0096"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="04-Apr-2024"
/note="genotype: GII.17[P17]"
gene <1..2865
/gene="ORF1"
CDS <1..2865
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39357.1"
/translation="AIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNE
LAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEG
DEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEY
KRIREERNGKYSIEEYLQDRDRYYEKLAIAKATEEDFCEEEEIKIRQRIFRPTRKQRK
EERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFG
TGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGM
ILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKS
MDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKG
TYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMR
DQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYP
HHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIK
KRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYH
YDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINE
GLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLD
PEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSIL
RQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGG
MDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..390
/gene="ORF1"
/product="p22"
mat_peptide 391..789
/gene="ORF1"
/product="VPg"
mat_peptide 790..1332
/gene="ORF1"
/product="Pro"
mat_peptide 1333..2862
/gene="ORF1"
/product="RdRp"
gene 2846..4462
/gene="ORF2"
CDS 2846..4462
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39358.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNSDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 4462..>4989
/gene="ORF3"
CDS 4462..>4989
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39359.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQEVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTK"
ORIGIN
1 gctataaaga acatcaccat caagaagtgc cagatagtgt acaatggatg cacctacacc
61 atggaatctg acgggaggaa caaggttgtg gttgaaaagg ttcaaaatgc aacagtccaa
121 accaacaatg aacttgcagg agcactccac cacctgagat ctgcaagaat aaggtattat
181 gtcaaatgct tccaagaagc tatttactct atactccaaa ttgctggtgc agccttcgtc
241 accacacgca tcgtgaggcg catgaacatc tcaaacctct ggtcgaagcc acccgtcgaa
301 gagggtgacg agcctgaaga caaagggggg tgtcccaagc ccagggatga agatgacctc
361 actattgact ccaaagacat taaagcagaa ggtaagaagg gcaagaacaa atctggccgg
421 ggcaagaaac acacagcttt ctcatccaag ggcctcagtg atgaagagta cgatgagtac
481 aagagaatca gggaggagag aaatggcaag tactcaatag aagaatacct ccaggatagg
541 gatagatact atgaaaagct tgccattgct aaggccactg aggaagactt ctgtgaagag
601 gaggaaatca aaattcgcca gagaatcttc cggcccacca ggaagcagcg gaaagaggaa
661 agagccacgc ttgggctcgt cacaggatcg gaaattagaa agaggaaccc agatgatttt
721 aagccaaaag gaaaattgtg ggctgatgac aacaggagtg tggactacaa tgagaggata
781 gattttgagg ctcccccaag tgtttggtct aggatagtca actttggtac aggatgggga
841 ttctgggtct ccccaagtct ctttataact tcaacacatg tcataccaaa aggaatcact
901 gaggcttttg gagttcccat taaccaaatt caaattcaca aatctggaga gttttgccgt
961 ttgcggtttc caaaaccaat caggccagac gtgagtggaa tgatcttgga agagggtgcc
1021 cctgaaggca ctgttgtttc cattctcatc aagaggacga caggggaact gatgcctctc
1081 gcagttagaa tgggaactca tgccacaatg aaaatccaag gtagaacggt gggcggtcaa
1141 atgggcatgc ttctcactgg ctcaaacgcc aaaagcatgg acctaggcac aacaccaggt
1201 gactgtgggt gcccatacat atacaaaagg ggcaatgact tcgtggtcat tggggtacac
1261 actgcggcag cccgtggagg taacacggtc atatgtgcca cacaggggag tgaaggcgaa
1321 gccaccctcg aaggaggtga caacaagggc acctattgtg gagcccccat cttgggacct
1381 ggcaacgcac caaaactgag cacaaaaaca aaattctgga gatcttctaa cgcgccgctc
1441 ccgccaggca cctatgaacc agcatacctt ggtggaaaag acccgcgtgt gaagggaggc
1501 ccatctctac aacaggttat gagagaccaa ctcaaacctt ttacagagcc cagagggaag
1561 ccaccaaagc caagtgtcct agaatcagca aagaagacca tcattaatgt tctggaacaa
1621 accattgacc cccctgaaaa gtggtcatat gcccaagctt gtgcatccct cgacaagaca
1681 acctccagtg gatacccgca tcacgtccgg aagaatgatt actggagtgg tgaatccttc
1741 acggggaaac ttgcagacca ggcctcaaaa gcaaatctca tgtatgagga aggtaagcac
1801 atgcaaccag tttacaccgc agcactcaaa gacgagctcg tgaaaactga caaaatttat
1861 ggcaagatca agaaaagact cctgtggggc tctgacctat ccaccatgat tcgatgcgcc
1921 agggcatttg gtggcctcat ggatgagctc aaagcaaatt gtatcacact ccctatcaga
1981 gttggtatga acatgaatga agatggtccc ataatatttg aaaagcactc caggtacagg
2041 taccactatg atgctgatta ttcccgctgg gattccacac aacagcgggc agtgctggaa
2101 gcggcacttg aaatcatggt gagattttct gctgagccac agttggcaca aatagtggca
2161 gaggacctgc tatcaccaag tgtggttgat gtgggcgatt tcaaaattgc tatcaatgaa
2221 ggcctaccat ctggcgtgcc ttgcacttca caatggaatt ctattgccca ctggttactc
2281 accctatgtg ccctgtctga agtgacagga ctaggccctg acatcataca agccaactcc
2341 atgtactctt tctatggtga tgatgagatt gtgagcacag acataaaatt agacccagag
2401 aaattgactg caaaactcaa agaatatggt cttaaaccca cccggcctga caagactgag
2461 gggccactgg tgattagtga ggacctgaat gggttgactt tcctccgccg aacagtcacc
2521 cgcgatccag cgggttggtt tggaaagttg gatcaaaact ccatcctcag acagctgtac
2581 tggacaaggg gacccaacca tgaagacccc agtgagacta tgataccaca cgcacagaga
2641 cctgtgcagc tcatggcatt gctaggagaa tcctccctac atggaccctc attttacagc
2701 aaagttagca agctggttat atctgaactt aaagagggag gaatggattt ttatgtgccc
2761 agacaagagt caatgttcag gtggatgagg ttctcagatc taagcacatg ggagggcgat
2821 cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg aatgacgccg ctccatctaa
2881 tgatggtgct gctggtctcg taccagaggg caataacgag acccttcccc tagaaccagt
2941 tgcgggcgca gccatagccg cacccgtcac tggccaaaat aatataattg acccctggat
3001 tagaacaaat tttgtgcaag caccaaatgg agagttcaca gtgtcaccca gaaactctcc
3061 tggagaaatt ttactaaacc tagaattggg ccctgatctg aacccttatt tggctcattt
3121 gtcaaggatg tataatggat atgctggtgg agttgaagtc caggttctcc tggcagggaa
3181 cgcgttcact gccgggaaga tcctcttcgc cgctgtcccg ccaaattttc cagtggaatt
3241 cttaagccca gcccagatta caatgctccc acatataata gtagatgtta ggactcttga
3301 accaattatg atcccgttac ctgatgttag gaatacattc ttccactata ataatcagcc
3361 caacagccgc atgagattag tggctatgct ctacaccccc cttagatcta atggctcagg
3421 tgatgatgtt ttcactgttt cttgcagggt tttgactagg cctactcctg attttgagtt
3481 cacttatcta gtgccaccct ctgttgaatc taagactaaa cccttttctt tacccattct
3541 aaccctctct gagctcacaa attcgaggtt cccggtcccc atcgattcgc ttttcaccgc
3601 ccaaaataat gtgttgcagg tgcaatgtca aaatggcagg tgcacacttg acggtgagct
3661 acaaggcaca acccagttgc tcccatctgg catctgtgcg ttcaggggac gggtaacagc
3721 agaaactgac aattctgaca agtggcacat gcaactgcaa aaccttaatg gcacaacata
3781 tgacccgact gatgatgtgc cagccccatt gggtacacct gacttcaagg gcgtcgtgtt
3841 tgggatggca agccaaagaa atgtgggtaa cgacgcgccc ggttcaacca ggtcccatga
3901 ggcggtgatt tcaacctaca gccccagatt tgttcctaaa ttaggctctg tcaatttcaa
3961 aagcaatgac gatgatttcc aattgcagcc aacaagattc acaccagtgg gcattaatga
4021 tgatggcaac caaccattca gacaatggga attaccagat tattcagggg tgcttacctt
4081 gaatatgaac cttgcccccc cggttgctcc aaatttccct ggcgaacaat tactattctt
4141 cagatcttct gtgccatgtt caggaggtta caaccaaggt attatagatt gccttatccc
4201 ccaggaatgg atccaacact tctaccagga atcagcacct tctcagtcag aagtggccct
4261 aatcaggtac gtcaaccccg acacgggtcg cacactgttt gaggcaaagt tgcataggtc
4321 aggctatatc actgtggctc actctggaga ctatcctctt gttgttccgg ctaatggata
4381 ctttagattt gactcttggg taaatcagtt ttactcactc gccccaatgg gaactgggaa
4441 tgggcgaagg agggctcagt aatggctgga gctttcattg caggattggc gggtgacatg
4501 ctcacgtcat ccgtgggctc cctggtgaac gcaggggcaa acgccatcaa ccaaaagata
4561 gactttgaaa acaacaaaca actccagtct gcttcctttc aacatgataa agagatgctc
4621 caagcgcagg tgaacgcaac caagcagctg caatctgaga tgatagccct aaagcaggag
4681 gttttggccg caggcggctt ttcccccact gatgcagcga ggggggccat cggtgcaccc
4741 atgacaaagg tgcttgactg gtctggcact cgatactggg ctcccaattc cacaaagaca
4801 actggttatt cggggcaatt cacctcctca cctgtgcaca tgcccagccc gagtgtccca
4861 caatcaaaac ccgcaaagcc caagtctcta ggttcttctt cttcttctag tagtgtttac
4921 agtatgtcta cccaattaac ttctctaaca tctggctctt ctagtaatgc ttcttctgct
4981 tctacaaaa
//