Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038582 | GII.17 | |
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| GII.P17 |
ORF1: 1..4263
ORF2: 4244..5860
ORF3: 5860..6639
LOCUS PZ038582 6663 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2024/GII.17[P17]/Bristol0089
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PZ038582
VERSION PZ038582.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 6663)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 6663)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6663
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2024/GII.17[P17]/Bristol0089"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="12-Mar-2024"
/note="genotype: GII.17[P17]"
gene <1..4263
/gene="ORF1"
CDS <1..4263
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39351.1"
/translation="TNIMNILATCDWTFAGIVESMILLAELFGVLWTPPDVSAIIAPL
LGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLE
ILKLVMKWFFPKKEEANELALVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLD
LEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRP
GIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQD
ALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDF
LVYADAPDIEKAKRDFPGQPDMWKDHYRTDFSHIKLQLAPQGGFDKSGNTPHGKGVVK
SLTIGSLIARASGLLHERMDEFELQGSNLPTFNFDRNKVAAFRQLAAENKYGLMDTLR
VGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTN
NELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVE
EGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYD
EYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQ
RKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVN
FGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVS
GMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNA
KSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDN
KGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQV
MRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSG
YPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGK
IKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYR
YHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAI
NEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIK
LDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNS
ILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKE
GGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..153
/gene="ORF1"
/product="p48"
mat_peptide 154..1251
/gene="ORF1"
/product="NTPase"
mat_peptide 1252..1788
/gene="ORF1"
/product="p22"
mat_peptide 1789..2187
/gene="ORF1"
/product="VPg"
mat_peptide 2188..2730
/gene="ORF1"
/product="Pro"
mat_peptide 2731..4260
/gene="ORF1"
/product="RdRp"
gene 4244..5860
/gene="ORF2"
CDS 4244..5860
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39352.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 5860..6639
/gene="ORF3"
CDS 5860..6639
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39353.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 acaaacatta tgaacatact ggcaacttgt gattggactt ttgcgggcat agtggaatcc
61 atgatccttc ttgctgaact ctttggggtg ctctggacgc ccccagatgt gtctgcaata
121 attgctccct tactcggtga ctacgagatg caaggccccg aagatctggc cgtggaactt
181 gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga aaagatcggc
241 aagatgcttt catcagctgc aaccacactc agggcctgta aggatctagg atcttatggg
301 ttggagatac tcaaactggt catgaagtgg ttcttcccca agaaggagga ggccaacgag
361 ttagccttgg taagggccat tgaggatgca gttctggatt tggaggcaat agaaaacaac
421 cacatgacca ctctccttaa ggacaaagac gccctggcca catacatgag gactcttgac
481 ttggaagaag aaaaagcaag gaaactgtct tccaaatcgg cgtcacctga catcgtgggc
541 acagtaaacg cattattggc aagaatagca gccgccaggt cactggtcca caaggctaag
601 gaggagctct cgagcagaca gagacctgtt gttgtaatga tatcaggtag gccaggtata
661 ggaaagaccc atctggccag agagctagcc aagaaggttg cgtcaacact gtcaggcgac
721 caaaggattg gactgatacc cagaaatggc gtcgaccatt gggacgccta caaaggagag
781 cgggtggttc tgtgggatga ctatggcatg agcaacccta tacaggacgc actgaggctc
841 caagaattgg ctgacacctg tcctctgacc ctaaattgtg acagaattga aaacaaagga
901 aaagtgttcg acagtgacgc cataatcata acaaccaacc ttgcaaaccc agcaccattg
961 gattatgtca actttgaggc ttgttccaga cgcatagact tcttggtgta tgcagacgca
1021 cctgacatcg agaaggccaa gcgtgacttc cctggccaac cagatatgtg gaaagaccat
1081 tacagaacag acttctcaca cattaaactt cagctcgcac cacagggagg ctttgataag
1141 agtggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg ttctctgatc
1201 gccagggctt ctggcttgct ccatgagaga atggatgaat tcgagctcca aggctccaac
1261 ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt ggcagctgaa
1321 aacaaatacg gtcttatgga cacactgagg gtcggcaacc aactgaaaag tgtcaaaacc
1381 ctggatgagc tgaagcaggc tataaagaac atcaccatca agaagtgcca gatagtgtac
1441 aatggatgca cctacaccat ggaatctgac gggaggaaca aggttgtggt tgaaaaggtt
1501 caaaatgcaa cagtccaaac caacaatgaa cttgcaggag cactccacca cctgagatct
1561 gcaagaataa ggtattatgt caaatgcttc caagaagcta tttactctat actccaaatt
1621 gctggtgcgg ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc aaacctctgg
1681 tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg tcccaagccc
1741 agggatgagg atgacctcac tattgactcc aaagacatta aagcagaagg taagaagggc
1801 aagaacaaat ctggccgggg caagaaacac acagctttct catccaaggg cctcagtgat
1861 gaagagtacg atgagtacaa gagaatcagg gaggagagaa atggcaagta ctcaatagaa
1921 gaatacctcc aggataggga tagatactat gaagagcttg ccattgctaa ggccactgag
1981 gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg gcccaccagg
2041 aagcagcgga aagaggaaag agccacgctt gggctcgtca caggatcgga aattagaaag
2101 aggaacccag atgattttaa gccaaaagga aaattgtggg ctgatgacaa caggagtgtg
2161 gactacaatg agaggataga ttttgaggct cccccaagtg tttggtctag gatagtcaac
2221 tttggtacag gatggggatt ctgggtctcc ccaagtctct ttataacttc aacacatgtc
2281 ataccaaaag gaatcactga ggcttttgga gttcccatta accaaattca aattcacaaa
2341 tctggagagt tttgccgttt gcggtttcca aaaccaatca ggccagacgt gagtggaatg
2401 atattggaag agggtgcccc tgaaggcact gttgtttcca ttctcatcaa gaggacgaca
2461 ggggaactga tgcctctcgc agttagaatg ggaactcatg ccacaatgaa aatccaaggt
2521 agaacggtgg gcggtcaaat gggcatgctt ctcactggct caaacgccaa aagcatggac
2581 ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg caatgacttc
2641 gtggtcattg gggtgcacac tgcggcagcc cgtggaggta acacggtcat atgtgccaca
2701 caggggagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac ctattgtgga
2761 gcccccatct tgggacctgg caacgcacca aaattgagca caaaaacaaa attctggaga
2821 tcttctaacg cgccgctccc gccaggcacc tatgaaccag catatcttgg tggaaaagac
2881 ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact caaacctttt
2941 acagagccca gagggaagcc accaaagcca agtgtcctag aatcagcaaa gaagaccatc
3001 attaatgttc tggaacaaac cattgacccc cctgaaaagt ggtcatatgc ccaagcttgt
3061 gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa gaatgattac
3121 tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc aaatctcatg
3181 tatgaggaag gtaagcacat gcaaccagtt tacaccgcag cactcaaaga cgagctcgtg
3241 aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc tgacctatcc
3301 accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa agcaaattgt
3361 atcacactcc ctatcagagt tggtatgaac atgaatgaag atggtcccat aatatttgaa
3421 aagcactcca ggtacaggta ccactatgat gctgattatt cccgctggga ttccacacaa
3481 cagcgggcag tgctggaagc ggcacttgaa atcatggtga gattttctgc tgagccacag
3541 ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt gggcgatttc
3601 aaaattgcta ttaatgaagg cctaccatct ggcgtgcctt gcacttcaca atggaattct
3661 attgcccact ggttactcac cctatgtgcc ctgtctgaag tgacaggact aggccctgac
3721 atcatacaag ccaactccat gtactctttc tatggtgatg atgagattgt gagcacagac
3781 ataaaattag acccagagaa attgactgca aaactcaaag aatatggtct taaacccacc
3841 cggcctgaca agactgaggg gccactggtg attagtgagg acctgaatgg gttgactttc
3901 ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga tcaaaactcc
3961 atcctcagac agctgtactg gacaagggga cccaaccatg aagaccccag tgagactatg
4021 ataccacacg cacagagacc tgtgcagctc atggcattgc taggagaatc ctccctacat
4081 ggaccctcat tttacagcaa ggttagcaag ctggttatat ctgaacttaa agagggagga
4141 atggattttt atgtgcccag acaagagtca atgttcaggt ggatgaggtt ctcagatcta
4201 agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgaa
4261 tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca ataacgagac
4321 ccttccccta gaaccagttg cgggcgcagc catagccgca cccgtcactg gccaaaataa
4381 tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag agttcacagt
4441 gtcacccaga aactctcctg gagaaatttt actaaaccta gaattgggcc ctgatctgaa
4501 cccttatttg gctcatttgt caaggatgta taatggatat gctggtggag ttgaagtcca
4561 ggttctcctg gcagggaacg cgttcactgc cgggaagatc ctcttcgccg ctgtcccgcc
4621 aaattttcca gtggaattct taagcccagc ccagattaca atgctcccac atataatagt
4681 agatgttagg actcttgaac caattatgat cccgttacct gatgttagga atacattctt
4741 ccactataat aatcagccca acagccgcat gagattagtg gctatgctct acacccccct
4801 tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt tgactaggcc
4861 tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta agactaaacc
4921 cttttcttta cccattctaa ccctttctga gctcacaaat tcgaggttcc cggtccccat
4981 cgattcgctt ttcaccgccc aaaataatgt gttgcaggtg caatgtcaaa atggcaggtg
5041 cacacttgac ggtgaactac aaggcacaac ccagttgctc ccatctggca tctgtgcgtt
5101 caggggacgg gtgacagcag aaactgacaa tcctgacaag tggcacatgc aactgcaaaa
5161 ccttaatggc acaacatatg acccgactga tgatgtgcca gccccattgg gtacacctga
5221 cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg acgcgcccgg
5281 ttcaaccagg tcccatgagg cggtgatttc aacctacagc cccagatttg ttcctaaatt
5341 aggctctgtc aatttcaaaa gcaatgacga tgatttccaa ttgcagccaa caagattcac
5401 accagtgggc attaatgatg atggcaacca accattcaga caatgggaat taccagatta
5461 ttcaggggtg cttaccttga atatgaacct tgcccccccg gttgctccaa atttccctgg
5521 cgaacaatta ctattcttca gatcttctgt gccatgttca ggaggttaca accaaggtat
5581 tatagattgc cttatccccc aagaatggat ccaacacttc taccaggaat cagcaccttc
5641 tcagtcagaa gtggccctaa tcaggtacgt caaccccgac acgggtcgca cactgtttga
5701 ggcaaaattg cataggtcag gctatatcac tgtggctcac tctggagact atcctcttgt
5761 tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt actcactcgc
5821 cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc tttcattgca
5881 ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc aggggcaaac
5941 gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc ttcctttcaa
6001 catgataaag agatgctcca agcgcaggtg aacgcaacca agcagctgca atctgagatg
6061 atagccctaa aacagggggt tttggccgca ggcggctttt cccccactga tgcagcgagg
6121 ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg atactgggct
6181 cccaattcca caaagacaac tggttattcg gggcaattca cctcctcacc tgtgcacatg
6241 cccagcccga gtgtcccaca atcaaaaccc gcaaagccca agtctctagg ttcttcttct
6301 tcttctagta gtgtttacag tatgtctacc caattaactt ctctaacatc tggctcttct
6361 agtaatgctt cttctgcttc tacaaaattg acaaatttaa gctccggctc ttctcaaaac
6421 agaacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag tggcgcactc
6481 aatatctcgc acgtcacgcc accttcgagt agggcctcca gttctgggac ggtctcaacc
6541 gtgcccaagg aagttttgga ctcctggaca tctgcattca acacacgcag acagccgctc
6601 ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat aattggctat
6661 aat
//