Typing tool
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Typing tool
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Complete norovirus genomes
| PZ038580 | GII.17 | |
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| GII.P17 |
ORF1: 1..3282
ORF2: 3263..4885
ORF3: 4885..5633
LOCUS PZ038580 5633 bp RNA linear VRL 14-JUL-2026
DEFINITION Norovirus GII isolate Hu/US/2022/GII.17[P17]/Kent0063 nonstructural
polyprotein (ORF1) gene, partial cds; VP1 (ORF2) gene, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION PZ038580
VERSION PZ038580.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 5633)
AUTHORS Barclay,L., Wikswo,M.E., Wall,H., Kambhampati,A.K.,
Montmayeur,A.M., Mallory,M.L., Lindesmith,L.C., Mirza,S.A.,
Baric,R.S., Vinje,J. and Chhabra,P.
TITLE Epidemiology and molecular evolution of norovirus GII.17 in the
United States, 2021-2025
JOURNAL J Infect Dis (2026) In press
PUBMED 42418796
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 5633)
AUTHORS Popowich,M., Barclay,L., Montmayeur,A.M., Vinje,J. and Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2026) Viral Gastroenteritis Branch, Division of
Viral Diseases, Centers for Disease Control and Prevention, 1600
Clifton Road NE, Atlanta/GA, GA 30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: CN 2.0 Pipeline v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..5633
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/US/2022/GII.17[P17]/Kent0063"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="11-May-2022"
/note="genotype: GII.17[P17]"
gene <1..3282
/gene="ORF1"
CDS <1..3282
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YDD39345.1"
/translation="CSRRIDFLVFADAPDIEKAKRDFPGQPDMWKDHFKPDFSHIKLQ
LAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGSDLPTFNFDRN
KIAAFRQLAAENKYGLMDTMRVGNQLKSVKTMDELKQAIKNISIKRCQIVYNGCTYTM
ESDGRGKVVVEKVQNATVQTNNELVGALHHLRSARIRYYVKCFQEAIYSLLQIAGAAF
VTSRIVRRMNISSLWSKPPIEEGDEPEDKEGCPKPRDGDDLTVDSKDIKVEGKKGKNK
SGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEE
DFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRS
VDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQ
IHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHAT
MKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGG
NTVICATQGNEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTY
EPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPNPNVLESAKKTIINVLEQTID
PPERWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHM
QPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPI
RVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQ
IVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDI
IQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLT
FLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGES
SLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVN
EDGVE"
mat_peptide <1..270
/gene="ORF1"
/product="NTPase"
mat_peptide 271..807
/gene="ORF1"
/product="p22"
mat_peptide 808..1206
/gene="ORF1"
/product="VPg"
mat_peptide 1207..1749
/gene="ORF1"
/product="Pro"
mat_peptide 1750..3279
/gene="ORF1"
/product="RdRp"
gene 3263..4885
/gene="ORF2"
CDS 3263..4885
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YDD39346.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPVLTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPAGICAFRGRVTAQINQDDRWHMQLQNFNGTTYDPTDDVPAPLGTPDFRGVVFGM
VSQRNVGNDAPGSTRAQQAMVSTYSPQFVPKLGSINLRISNNDDFQFQPTKFTPVGVN
DDGDDHPFRQWELPDYSGALTLNMNLAPPVAPNFPGEQLLFFRSAVPCSGGYNQGIID
CLLPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 4885..>5633
/gene="ORF3"
CDS 4885..>5633
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YDD39347.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQEQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTRVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPNVPQSKSAKPRSLASSSSSSSVYSMYTQST
QLTPGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMRGALNISHVTPPSSS
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFA"
ORIGIN
1 tgctctagac gcatagactt cttggtgttt gcagacgcac ctgacattga gaaagctaag
61 cgtgacttcc ctggccaacc agacatgtgg aaagaccatt tcaaaccaga cttctcacac
121 attaaactcc agctggcacc acaggggggt tttgataaaa atggcaacac cccacacggc
181 aagggtgtgg tgaagtccct gacgattggc tcgctgatcg ccagggcctc tggcttgctc
241 cacgagagaa tggatgaatt cgagctccaa ggctctgacc tgccaacctt caattttgac
301 cgcaataaaa tcgccgcctt cagacaatta gcagctgaaa acaaatatgg ccttatggac
361 acaatgaggg tcggcaacca gctgaaaagt gttaagacca tggatgagct gaaacaagcc
421 ataaagaaca tcagtattaa gagatgtcag atagtgtaca atggatgcac ctataccatg
481 gagtctgatg ggaggggcaa ggttgtggtt gaaaaggtac aaaacgcaac agttcaaacc
541 aacaatgaac ttgtaggggc actccaccac ctgagatctg caaggataag atactatgtc
601 aagtgtttcc aagaagccat ttactctcta ctccaaattg ctggtgcagc cttcgtcact
661 tcacgcatcg tgaggcgcat gaacatatca agcctctggt cgaagccacc catcgaggaa
721 ggtgatgaac ctgaagacaa agaaggatgc cccaagccca gggatggaga tgacctcact
781 gttgactcca aagacatcaa agtggaaggg aagaaaggca agaacaagtc tggccggggc
841 aagaaacaca cagccttctc ttccaagggc ctcagtgatg aagagtacga tgagtacaag
901 agaatcagag aggagaggaa tggaaagtac tcaatagagg aatacctcca agatagggac
961 agatactatg aagagcttgc cattgctaag gccactgagg aggacttttg tgaggaggag
1021 gagatcaaaa tccgccaaag aatcttccga cccaccagga agcagcggaa agaggaaagg
1081 gccacactcg ggcttgtcac aggatcggaa attagaaaga ggaatccaga tgactttaaa
1141 ccaaaaggaa aattgtgggc tgatgacgac aggagcgtgg attacaatga gaggatagat
1201 tttgaggctc ccccgagtgt ttggtctaga atagtcaact ttggcacagg ctggggattc
1261 tgggtttctc caagtctctt tataacttca acacatgtca taccaaaagg aatcactgag
1321 gcctttggag tgcccataaa ccaaatccaa attcacaaat ctggagaatt ttgccgcttg
1381 cggtttccaa agccaattag accagacgtg agtgggatga tcttggaaga aggcgcccct
1441 gaaggcactg ttgtgtctat tctcatcaaa agaacaacag gggagctgat gcctcttgca
1501 gtcagaatgg ggacccatgc cacaatgaaa atccaaggta gaacggtggg tggtcagatg
1561 ggcatgcttc tcactggctc aaatgctaaa agcatggatc tgggcacaac gccaggtgac
1621 tgcggatgtc catacatata caaaaggggc aatgactttg tggtcattgg ggtgcacact
1681 gcagcggccc gtggaggcaa cacggtcata tgtgccacac agggaaatga aggtgaagcc
1741 actcttgaag gaggtgacaa caagggtacc tattgtggag cccccatttt gggacctggc
1801 aatgcaccaa aattgagcac aaaaaccaaa ttctggaggt cctctaacgc accgcttccc
1861 ccaggtactt atgaaccagc ataccttggt gggaaagacc cgcgcgtgaa gggaggccca
1921 tctctgcaac aagttatgag agaccaactt aaacctttta cagagcccag agggaaacca
1981 ccaaacccaa atgtcttaga gtcagcaaag aaaactatca tcaatgttct ggaacaaacc
2041 attgaccccc cagagaggtg gtcatatgcc caagcttgtg catccctcga caagacaacc
2101 tccagcggat acccgcacca cgtccggaag aatgactatt ggagtggtga atccttcaca
2161 ggaaaacttg cagatcaggc ttcaaaagca aatctcatgt atgaggaggg caagcacatg
2221 caaccagttt acaccgcagc actcaaagac gagctcgtga aaactgacaa aatttatgga
2281 aaaatcaaga aaagactcct gtggggttct gacctttcca caatgattcg atgcgccaga
2341 gcatttggtg gtctcatgga tgaattaaaa gcaaattgta tcacactccc tatcagagtt
2401 ggtatgaata tgaatgagga tggtcccata atatttgaga aacactccag gtacaggtac
2461 cactatgatg ctgattactc ccgctgggat tcaacacaac agcgggcagt gctggaagcg
2521 gcacttgaaa tcatggtgag gttttctgct gagccacagc tggcacaaat agtggcagag
2581 gacctgctgt caccaagtgt ggttgatgtg ggagatttca aaatcaccat caatgaaggc
2641 ctaccgtctg gtgtgccttg cacctcacaa tggaattcta ttgcccactg gttactcacc
2701 ttgtgtgccc tttctgaagt gacgggatta ggtcctgaca tcatacaagc caactcaatg
2761 tactctttct atggtgatga tgaaattgtg agtacagaca taaaattgga cccagaaaaa
2821 ttgaccgcaa agctcaaaga atatggcctt aaacccactc ggcccgacaa aactgagggg
2881 ccgttggtga tcagtgagga cctgaatggg ttgactttcc tccgccgaac agtcacccgt
2941 gatccagcag gttggtttgg gaagttggac caaaattcca tcctcaggca gctgtactgg
3001 acgagaggac ccaaccatga agaccccagt gagaccatga taccacacgc acaaagacct
3061 gtgcagctca tggcactact aggtgaatcc tccctgcatg gaccctcatt ttacagtaag
3121 gttagcaaat tagttatatc tgaacttaaa gagggaggaa tggattttta tgtgcccaga
3181 caagagtcaa tgttcagatg gatgaggttc tcagatctaa gcacatggga gggcgatcgc
3241 aatctggctc ccagttttgt gaatgaagat ggcgtcgaat gacgccgctc catctaatga
3301 tggtgctgct ggtctcgtac cagagggcaa caacgagacc cttcccctag aaccagttgc
3361 aggcgcagct atagccgcac ccgtcactgg ccaaaacaat ataattgacc cctggattag
3421 aacaaatttt gtgcaagcac caaatggaga gttcacagtg tcacccagaa actctcctgg
3481 agaaatttta ttaaatttag agttgggccc tgatttgaac ccctatttgg cccatttgtc
3541 aaggatgtac aatgggtatg ctggtggagt ggaagtccag gttctcctgg cagggaacgc
3601 gttcactgcc ggaaagatcc tcttcgccgc cgtcccgcca aatttcccag tggaattctt
3661 aagcccagcc cagatcacaa tgctcccaca tttaatagta gatgttagaa cccttgaacc
3721 aattatgatc ccactccctg atgttaggaa cacattcttc cattataata atcagcctaa
3781 tagccgcatg agactagtgg ctatgctcta taccccactc agatctaatg gctcaggtga
3841 tgatgtcttt actgtctcct gcagggtttt gactaggcct actcctgact ttgagttcac
3901 ttatttagtg ccaccttctg ttgaatccaa aactaagcct ttttccttac ctgttttaac
3961 cctttctgag cttacaaatt cgaggtttcc agtccccatc gattcgcttt tcaccgccca
4021 gaataatgtg ttgcaggtgc agtgtcaaaa tggcaggtgt acacttgatg gtgagttgca
4081 aggcacaacc caattgctcc cagctggcat ctgtgcattc agaggacggg tgacagcaca
4141 aattaaccaa gatgacaggt ggcacatgca actgcaaaac ttcaatggta caacatatga
4201 cccaactgat gatgtgccag ccccgctggg tacacctgac ttcaggggcg tcgtgtttgg
4261 gatggtgagc caaagaaatg taggtaatga tgcgcctggc tcaaccagag cccaacaggc
4321 gatggtttca acctatagcc cccaatttgt ccccaaatta ggttctatca atcttagaat
4381 tagtaataat gatgatttcc agttccagcc gacaaaattc acaccagtgg gcgtcaatga
4441 tgacggtgat gaccacccgt tcagacaatg ggaattacca gactattcag gggcgcttac
4501 cttgaatatg aatcttgccc ccccagttgc tccaaatttt cctggtgaac aattgttgtt
4561 cttcagatcc gccgtgccat gctcaggagg ctacaaccaa ggtattatag attgtcttct
4621 tccccaagaa tggatccaac acttctatca ggaatcagca ccctcccaat cagatgtggc
4681 cctaatcagg tatgtcaatc ccgatacggg gcgtacactg tttgaagcaa aattgcacag
4741 atctggttac attactgtgg ctcattctgg agactatcct cttgttgttc cggctaatgg
4801 atactttagg tttgattctt gggtaaatca gttttactca ctcgccccaa tgggaactgg
4861 gaatgggcga aggagggctc agtaatggct ggagctttca ttgcaggatt ggcaggcgac
4921 atgctcacgt catctgtggg ctcccttgtg aacgcagggg caaacgccat caaccaaaag
4981 atagactttg aaaataacaa acaactccag tctgcttcct tccagcatga taaagaaatg
5041 ctccaagagc aggtgagggc gaccaagcaa ctgcaatctg aaatgatagc cctaaagcag
5101 ggggttttgg ccgcaggcgg cttttccccc actgatgcag caaggggatc cattggtgct
5161 cccatgacaa gggtgcttga ctggtctggc acccggtact gggcgcccaa ctccacaaag
5221 acaactggct attcggggca attcacctct tcacctgtgc atatgcctag cccaaatgtc
5281 ccacaatcaa aatctgcaaa acctaggtct ctagcttctt cttcttcctc tagtagtgtc
5341 tatagtatgt atacccaatc tactcaacta acacctggct cttctagtaa tgcttcttct
5401 gcctctacaa aattgacaaa tttaagctct ggctcctctc aaaatagaac agcagaatgg
5461 gtaaatcaac aaagaagtct tagccctttc atgcgtggcg cactcaacat ctcacatgtc
5521 acgccaccct cgagtagtgc ttctagttct gggacggtct cgaccgtgcc caaggaagtt
5581 ttggactcct ggacatctgc atttaacaca cacagacagc cgctcttcgc aca
//