Typing tool
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Typing tool
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Complete norovirus genomes
| PX700456 | GII.17 | |
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| GII.P17 |
ORF1: 1..5012
ORF2: 4993..6609
ORF3: 6609..7349
LOCUS PX700456 7349 bp RNA linear VRL 04-MAR-2026
DEFINITION Norovirus GII isolate 2414YC12 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION PX700456
VERSION PX700456.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7349)
AUTHORS Jin,m., yin,a. and yang,s.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2025) National Key Laboratory of Infectious
Disease Source Tracing, Early Warning and Intelligent
Decision-making, Institute of Viral Disease Control and Prevention,
China CDC, No. 155, Changbai Road, Changping District, Beijing
102206, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7349
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="2414YC12"
/isolation_source="anal swab"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Beijing,Changping"
/collection_date="Dec-2024"
/note="genotype: GII.17[P17]"
gene <1..5012
/gene="ORF1"
CDS <1..5012
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="YCB08087.1"
/translation="TVTFKKALGARSKQPPPGETKQTLRPPRPPTPELVKKIPPPPPN
GEDEPKVTYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLSQREVGEAREPLPGSILEM
WDGEIYHYGLYVERGHVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQYLIAPETLKN
LNGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDE
PKIKKAANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAEL
FGVFWTPPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSS
AATTLRACKDLGSYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMT
TLLKDKDALATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKE
ELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKG
ERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANP
APLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQ
GGFDKSGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGPDLPTFNFDRNKVAA
FRQLAAENKYGLMDTLRVGNQLKSVKTLDELNQAIKNITIKKCQIVYNGCTYTMESDG
RNKVVVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTR
IVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRG
KKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEEFCE
EEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYN
ERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKS
GEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQ
GRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVI
CATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAY
LGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEK
WSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVY
TAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGM
NMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAE
DLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQAN
SMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRR
TVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHG
PSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGV
E"
mat_peptide <1..902
/gene="ORF1"
/product="p48"
mat_peptide 903..2000
/gene="ORF1"
/product="NTPase"
mat_peptide 2001..2537
/gene="ORF1"
/product="p22"
mat_peptide 2538..2936
/gene="ORF1"
/product="VPg"
mat_peptide 2937..3479
/gene="ORF1"
/product="Pro"
mat_peptide 3480..5009
/gene="ORF1"
/product="RdRp"
gene 4993..6609
/gene="ORF2"
CDS 4993..6609
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YCB08088.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6609..>7349
/gene="ORF3"
CDS 6609..>7349
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YCB08089.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSPSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPL"
ORIGIN
1 tgactgttac ttttaagaaa gccctcgggg cgcggtctaa gcagccgccc ccgggagaaa
61 caaaacaaac actaagacca ccaaggccgc cgacaccgga attggtgaag aagatacccc
121 cacccccccc caatggcgag gatgaaccaa aggtaacgta taaggtggga gaaggtgtgt
181 ctgggctgcc cgacttaaca accgtggcac aacctgacgc acagaacaca gcctatagtg
241 tccccccact tagccagaga gaggtcggcg aagctagaga accgttgcct ggctccattc
301 tggaaatgtg ggatggtgag atctaccact atgggctgta tgttgagcgg gggcatgtgc
361 tgggagtgca caaaccacct gctgcaataa gccttgccaa aattgagtta acaccgctgt
421 ctctctactg gagagtggtc tacactcccc agtacttgat agctccagag accctcaaga
481 atttaaatgg agagactttc ccatacacgg cctttgacaa caactgttat gccttctgtt
541 gttgggttct agacctcaac gactcctggc ttagcagaag aatggtccaa agaacaaccg
601 gattcttcag accgtatcag gactggaaca gaaaaccctt accaaccatg gatgaaccaa
661 aaatcaagaa ggccgcgaat gctgttctgt gtgctctctc ctcactcttc actaggccca
721 tcaaagatgt cattggaaag cttaaaccac taaacattat gaacatactg gcaacttgtg
781 attggacttt tgcgggcata gtggaatcca tgatccttct tgctgaactc tttggggtgt
841 tctggacgcc cccagatgtg tctgcaataa ttgctccctt actcggtgac tacgagatgc
901 aaggccccga agacctggcc gtggaacttg tgcccgtggt aatgggagga ataggtttgg
961 tgttaggatt caccaaggaa aagatcggca agatgctttc atcagctgca accacactca
1021 gggcctgtaa ggatctagga tcttatgggt tggagatact caaactggtc atgaagtggt
1081 tcttccccaa gaaggaggag gccaacgagt tagccatggt gagggccatt gaggatgcag
1141 ttctggattt ggaggcaata gaaaacaacc acatgaccac tctccttaag gacaaagacg
1201 ccctggccac atacatgagg actcttgact tggaagaaga aaaagcaagg aaactatctt
1261 ccaaatcggc gtcacctgac atcgtgggca cagtaaacgc attattggca agaatagcag
1321 ccgccaggtc actggtccac aaggctaagg aggagctctc gagcagacag agacctgttg
1381 ttgtaatgat atcaggtagg ccaggtatag gaaagaccca tctggccaga gagctagcca
1441 agaaggttgc gtcaacactg tcaggcgacc aaaggattgg actgataccc agaaatggcg
1501 tcgaccattg ggacgcctac aaaggagagc gggtggttct gtgggatgac tatggcatga
1561 gcaaccctat acaggacgca ctgaggctcc aagaattggc tgacacctgt cctctgaccc
1621 taaattgtga cagaattgaa aacaaaggaa aagtgttcga cagcgacgcc ataatcataa
1681 cgaccaacct tgcaaaccca gcaccattgg attatgtcaa ctttgaggct tgttccagac
1741 gcatagactt cttggtgtat gcagacgcac ctgacatcga gaaggctaag cgtgactttc
1801 ctggccaacc agatatgtgg aaagaccatt acagaccaga cttctcacac attaaacttc
1861 agctcgcacc acagggaggc tttgataaga gtggcaacac cccacatggc aaaggcgtgg
1921 ttaagtctct gacgattggc tctctgatcg ccagggcttc tggcttgctc catgagagaa
1981 tggatgaatt cgagctccaa ggccccgact taccaacctt caatttcgac cgtaacaaag
2041 tcgccgcctt cagacaattg gcagctgaaa acaaatacgg tcttatggac acactgaggg
2101 tcggcaacca actgaaaagt gtcaaaaccc tggatgagct gaatcaggcc ataaagaaca
2161 tcactatcaa gaagtgccag atagtgtaca atggatgcac ctacaccatg gaatctgatg
2221 ggaggaacaa ggttgtggtt gaaaaggttc aaaatgcaac agtccaaacc aacaatgaac
2281 ttgcaggagc actccaccac ctgagatctg caagaataag gtattatgtc aaatgtttcc
2341 aagaagctat ttactctata ctccaaattg ctggtgcagc cttcgtcacc acacgcatcg
2401 tgaggcgcat gaacatctca aacctctggt cgaagccacc cgtcgaagag ggtgatgagc
2461 ctgaagacaa aggggggtgc cccaagccca gggatgaaga tgacctcact attgactcca
2521 aagacattaa agcagaaggt aagaagggca agaacaaatc tggccggggc aagaaacaca
2581 cagctttctc atccaagggc ctcagtgatg aagagtacga tgagtacaag agaatcaggg
2641 aggagagaaa tggcaagtac tcaatagaag aataccttca ggatagggat agatactatg
2701 aagagcttgc cattgctaag gccactgagg aagagttttg tgaagaggag gaaatcaaaa
2761 ttcgccagag aatcttccgg cccaccagga agcagcggaa agaggaaaga gccacgcttg
2821 ggctcgtcac aggatcggaa atcagaaaga ggaacccaga tgattttaag ccaaaaggaa
2881 aattgtgggc tgatgacaac aggagtgtgg actacaatga gaggatagat tttgaggctc
2941 ccccaagtgt ttggtctagg atagtcaact ttggtacagg atggggattc tgggtctccc
3001 caagtctctt tataacttca acacatgtca taccaaaagg aattactgag gcctttggag
3061 ttcccattaa ccaaattcaa attcacaaat ctggagagtt ttgccgcttg cggtttccaa
3121 aaccaatcag gccagacgtg agtggaatga tcttggaaga gggtgcccct gaaggcactg
3181 ttgtttccat tctcatcaag aggacgacag gggaactgat gcctctcgca gtcagaatgg
3241 gaactcatgc cacaatgaaa atccaaggta gaacggtggg cggtcaaatg ggcatgcttc
3301 tcactggctc aaacgccaaa agcatggacc taggcacaac accaggtgac tgtgggtgcc
3361 catacatata caaaaggggc aatgacttcg tggtcattgg ggtgcacact gcagcagccc
3421 gtggaggtaa cacggtcata tgtgccacac aggggagtga aggcgaagcc accctcgaag
3481 gaggtgacaa caagggcacc tattgtggag cccccatctt gggtcctggc aacgcaccaa
3541 aattgagcac aaaaacaaaa ttctggagat cttctaacgc gccgctcccg ccaggcacct
3601 acgaaccagc ataccttggt ggaaaagacc cgcgtgtgaa gggaggccca tctctacaac
3661 aggttatgag agaccaactc aaacctttta cagagcccag agggaagcca ccaaaaccaa
3721 gtgtcctaga atcagcaaag aagaccatca ttaatgttct ggaacaaacc attgaccccc
3781 ctgaaaagtg gtcatatgcc caagcttgtg catccctcga caagacaacc tccagtggat
3841 acccgcatca cgtccggaag aatgactact ggagtggtga atccttcacg gggaaacttg
3901 cagaccaggc ctcaaaagca aatctcatgt atgaggaagg taagcacatg caaccagttt
3961 acaccgcagc actcaaagac gagctcgtga aaactgacaa aatttatggc aagatcaaga
4021 aaagactcct gtggggctct gacctatcca ccatgattcg atgcgccagg gcatttggtg
4081 gcctcatgga cgagctcaaa gcaaattgta tcacactccc tatcagagtt ggtatgaaca
4141 tgaatgaaga tggtcccata atatttgaaa agcactccag gtacaggtac cactatgatg
4201 ctgattattc ccgctgggat tccacacaac agcgggcagt gctggaagcg gcacttgaaa
4261 tcatggtgag attttctgct gagccacagt tggcacaaat agtggcagag gacctgctat
4321 caccaagtgt ggttgatgtg ggcgatttca aaattactat taatgaaggc ctaccatctg
4381 gcgtgccttg cacttcacaa tggaattcta ttgcccactg gttactcacc ctatgtgccc
4441 tgtctgaagt gacaggacta ggccctgaca tcatacaagc caactccatg tactctttct
4501 atggtgatga tgagattgtg agcacagaca taaaattaga cccagagaaa ttgactgcaa
4561 aactcaaaga atatggtctt aaacccaccc ggcctgacaa gactgagggg ccactggtaa
4621 ttagtgagga cctgaatggg ttgactttcc tccgccgaac agtcacccgc gatccagcgg
4681 gttggtttgg aaagttggac caaaactcca tcctcagaca gctgtactgg acaaggggac
4741 ccaaccatga agaccccagt gagactatga taccacacgc acagagacct gtgcagctca
4801 tggcattgct aggagaatcc tccctacatg gaccctcatt ttacagcaag gttagcaaac
4861 tggttatatc tgaacttaaa gagggaggaa tggattttta tgtgcccagg caagagtcaa
4921 tgttcaggtg gatgaggttc tcagatctaa gcacatggga gggcgatcgc aatctggctc
4981 ccagttttgt gaatgaagat ggcgtcgaat gacgccgctc catctaatga tggtgctgct
5041 ggtctcgtac cagagggcaa taacgagacc cttcccctag aaccagttgc gggcgcagcc
5101 atagccgcac ccgtcactgg ccaaaataat ataattgacc cctggattag aacaaatttt
5161 gtgcaagcac caaatggaga gttcacagtg tcacccagaa actctcctgg agaaatttta
5221 ctaaacctag agttgggccc tgatctgaac ccttatttgg ctcatttgtc aaggatgtat
5281 aatggatatg ctggtggagt tgaagtccag gttctcctgg cagggaacgc gttcactgcc
5341 gggaagatcc tcttcgccgc tgtcccgcca aattttccgg tggaattctt aagcccagcc
5401 cagattacaa tgctcccaca tataatagta gatgttagga ctcttgaacc aattatgatc
5461 ccattacctg atgttaggaa tacattcttc cactataata atcagcccaa cagccgcatg
5521 agattagtgg ctatgctcta cacccctctt agatctaatg gctcaggtga tgatgttttc
5581 actgtttctt gcagggtttt gactaggcct actcctgatt ttgagttcac ttatctagtg
5641 ccaccctctg ttgaatctaa gactaaaccc ttttctttac ccattctaac cctttctgag
5701 ctcacaaatt cgaggttccc ggtccccatc gattcgcttt tcaccgccca aaataatgtt
5761 ttgcaggtgc agtgtcaaaa tggcaggtgc acacttgacg gtgagctaca aggcacaacc
5821 cagttgctcc catctggcat ctgtgcgttc agggggcggg tgacagcaga aactgacaat
5881 cctgacaagt ggcacatgca actgcaaaac cttaatggca caacatatga cccaactgat
5941 gatgtgccag ccccactggg tacacctgac ttcaagggcg tcgtgtttgg gatggcaagc
6001 caaagaaatg tgggtaacga cgcgcccggc tcaaccaggt cccatgaggc ggtgatttca
6061 acctacagcc ccagatttgt tcctaaatta ggctctgtca atttcaaaag caatgatgat
6121 gatttccaat tgcagccaac aagattcaca ccagtgggca ttaatgatga tggcaaccaa
6181 ccatttagac aatgggaact accagattat tcaggagtgc ttaccttgaa tatgaacctt
6241 gccccccctg ttgctccaaa tttccctggc gaacaattac tattcttcag atcttctgtg
6301 ccatgttcag gaggttacaa ccaaggtatt atagattgcc ttatccccca agaatggatc
6361 caacacttct accaggaatc agcaccttct cagtcagaag tggccctaat caggtacgtc
6421 aaccccgaca cgggtcgtac actgtttgag gcaaaattgc ataggtcagg ctatatcact
6481 gtggctcatt ctggagatta tcctcttgtt gttccggcta atggatactt tagatttgac
6541 tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa ctgggaatgg gcgaaggagg
6601 gctcagtaat ggctggagct ttcattgcag gattggcggg tgacatgctc acgtcatccg
6661 tgggctccct ggtgaacgca ggggcaaacg ccatcaacca aaagatagac tttgaaaaca
6721 acaaacaact ccagtctgct tcctttcaac atgataaaga gatgctccaa gcgcaggtga
6781 acgcaaccaa gcagctgcaa tctgagatga tagccctaaa acagggggtt ttggccgcag
6841 gcggcttttc ccccactgat gcagcgaggg gggccatcgg tgcacccatg acaaaggtgc
6901 ttgactggtc tggcactcga tactgggctc ccaattccac aaagacaact ggttattcgg
6961 ggcaattcac ctcttcacct gtgcacatgc ccagcccgag tgtcccacaa tcaaaacccg
7021 caaagcccaa gtctctaggt tctccttctt cttctagtag tgtttacagt atgtctaccc
7081 aattaacttc tctaacatct ggctcttcta gtaatgcttc ttctgcttct acaaaattga
7141 caaatttgag ctccggctct tctcaaaaca gaacagcaga gtgggtgaac caacagagaa
7201 gtctcagccc tttcatgagt ggcgcactca atatctcgca tgtcacgcca ccttcaagta
7261 gggcctccag ttctgggacg gtctcaaccg tgcccaagga agttttggac tcctggacat
7321 ctgcattcaa cacacacaga cagccgctc
//