Typing tool
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Typing tool
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Complete norovirus genomes
| PX700453 | GII.17 | |
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| GII.P17 |
ORF1: 1..4969
ORF2: 4950..6566
ORF3: 6566..7276
LOCUS PX700453 7276 bp RNA linear VRL 04-MAR-2026
DEFINITION Norovirus GII isolate 2414YC07 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION PX700453
VERSION PX700453.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7276)
AUTHORS Jin,m., yin,a. and yang,s.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2025) National Key Laboratory of Infectious
Disease Source Tracing, Early Warning and Intelligent
Decision-making, Institute of Viral Disease Control and Prevention,
China CDC, No. 155, Changbai Road, Changping District, Beijing
102206, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7276
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="2414YC07"
/isolation_source="anal swab"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Beijing,Changping"
/collection_date="Dec-2024"
/note="genotype: GII.17[P17]"
gene <1..4969
/gene="ORF1"
CDS <1..4969
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="YCB08078.1"
/translation="PPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEG
VSGLPDLTTVAQPDAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVER
GHVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNN
CYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCAL
SSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAII
APLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSY
GLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMR
TLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMIS
GRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNP
IQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRR
IDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKG
VVKSLTIGSLIARASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMD
TLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATV
QTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKP
PVEEDDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDE
EYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPT
RKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSR
IVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRP
DVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTG
SNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEG
GDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSL
QQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTT
SSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKI
YGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHS
RYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAGDLLSPSVVDVGDFK
ITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVST
DIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLD
QNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISE
LKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..859
/gene="ORF1"
/product="p48"
mat_peptide 860..1957
/gene="ORF1"
/product="NTPase"
mat_peptide 1958..2494
/gene="ORF1"
/product="p22"
mat_peptide 2495..2893
/gene="ORF1"
/product="VPg"
mat_peptide 2894..3436
/gene="ORF1"
/product="Pro"
mat_peptide 3437..4966
/gene="ORF1"
/product="RdRp"
gene 4950..6566
/gene="ORF2"
CDS 4950..6566
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YCB08079.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAEADNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6566..>7276
/gene="ORF3"
CDS 6566..>7276
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YCB08080.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLISGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWT"
ORIGIN
1 gccgcccccg ggagaaacaa aacaaacact aagaccacca aggccgccga caccggaatt
61 ggtgaagaag atacccccac ccccccccaa tggcgaggat gaaccaaagg taacgtataa
121 ggtgggagaa ggtgtgtctg ggctgcccga cttaacaacc gtggcacaac ctgacgcaca
181 gaacacagcc tatagtgtcc ccccacttag ccagagagag gtcggcgaag ctagagaacc
241 gttgcctggc tccattctgg aaatgtggga tggtgagatc taccactatg ggctgtatgt
301 tgagcggggg catgtgctgg gagtgcacaa accacctgct gcaataagcc ttgccaaaat
361 tgagttaaca ccgctgtctc tctactggag agtggtctac actccccagt acttgatagc
421 tccagagacc ctcaagaatt taaatggaga gactttccca tacacggcct ttgacaacaa
481 ctgttatgcc ttctgttgtt gggttctaga cctcaacgac tcctggctta gcagaagaat
541 ggtccaaaga acaaccggat tcttcagacc gtatcaggac tggaacagaa aacccttacc
601 aaccatggat gaaccaaaaa tcaagaaggc cgcgaatgct gttctgtgtg ctctctcctc
661 actcttcact aggcccatca aagatgtcat tggaaagctt aaaccactaa acattatgaa
721 catactggca acttgtgatt ggacttttgc gggcatagtg gaatccatga tccttcttgc
781 tgaactcttt ggggtgttct ggacgccccc agatgtgtct gcaataattg ctcccttact
841 cggtgactac gagatgcaag gccccgaaga cctggccgtg gaacttgtgc ccgtggtaat
901 gggaggaata ggtttggtgt taggattcac caaggaaaag atcggcaaga tgctttcatc
961 agctgcaacc accctcaggg cctgtaagga tctaggatct tatgggttgg agatactcaa
1021 actggtcatg aagtggttct tccccaagaa ggaggaggcc aacgagttag ccatggtgag
1081 ggccattgag gatgcagttc tggatttgga ggcaatagaa aacaaccaca tgaccactct
1141 ccttaaggac aaagacgccc tggccacata catgaggact cttgacttgg aagaagaaaa
1201 agcaaggaaa ctatcttcca aatcggcgtc acctgacatc gtgggcacag taaacgcatt
1261 attggcaaga atagcagccg ccaggtcact ggtccacaag gctaaggagg agctctcgag
1321 cagacagaga cctgttgttg ttatgatatc aggtaggcca ggtataggaa agacccatct
1381 ggccagagag ctagccaaga aggttgcgtc aacactgtca ggcgaccaaa ggattggact
1441 gatacccaga aatggcgtcg accattggga cgcctacaaa ggagagcggg tggttctgtg
1501 ggatgactat ggcatgagca accctataca ggacgcactg aggctccaag aattggctga
1561 cacctgtcct ctgaccctaa attgtgacag aattgaaaac aaaggaaaag tgttcgacag
1621 tgacgccata atcataacga ccaaccttgc aaacccagca ccattggatt atgtcaactt
1681 tgaggcttgt tccagacgca tagacttctt ggtgtatgca gacgcacctg acatcgagaa
1741 ggctaagcgt gactttcctg gccaaccaga tatgtggaaa gaccattaca gaccagactt
1801 ttcacacatt aaacttcagc tcgcaccaca gggaggcttt gataagagtg gcaacacccc
1861 acatggcaaa ggcgtggtta agtctctgac gattggctct ctgatcgcca gggcttctgg
1921 cttgctccat gagagaatgg atgaattcga gctccaaggc cccaacttac caaccttcaa
1981 tttcgaccgt aacaaagtcg ccgccttcag acaattggca gctgaaaaca aatacggtct
2041 tatggacaca ctgagagtcg gcaaccaact gaaaagtgtc aaaaccctgg atgagctgaa
2101 gcaggccata aagaacatca ccatcaagaa gtgccagata gtgtacaatg gatgcaccta
2161 caccatggaa tctgatggga ggaacaaggt tgtggttgaa aaggttcaaa atgcaacagt
2221 ccaaaccaac aatgaacttg caggagcact ccaccacctg agatctgcaa gaataaggta
2281 ttatgtcaaa tgtttccaag aagctattta ctctatactc caaattgctg gtgcagcctt
2341 cgtcaccaca cgcatcgtga ggcgcatgaa catctcaaac ctctggtcga agccacccgt
2401 cgaagaggat gatgagcctg aagacaaagg ggggtgcccc aagcccaggg atgaagatga
2461 cctcactatt gactccaaag acattaaagc agaaggtaag aagggcaaga acaaatctgg
2521 ccggggcaag aaacacacag ctttctcatc caagggcctc agtgatgaag agtacgatga
2581 gtacaagaga atcagggagg agagaaatgg caagtactca atagaagaat acctccagga
2641 tagggataga tactatgaag agcttgccat tgctaaggcc actgaggaag acttctgtga
2701 agaggaggaa atcaaaattc gccagagaat cttccggccc actaggaagc agcggaaaga
2761 ggaaagagcc acgcttgggc tcgtcacagg atcggaaatc agaaagagga acccagatga
2821 ttttaagcca aaaggaaaat tgtgggctga tgacaacagg agtgtggact acaatgagag
2881 gatagatttt gaggctcccc caagtgtttg gtctaggata gtcaactttg gtacaggatg
2941 gggattctgg gtctccccaa gtctctttat aacttcaaca catgtcatac caaaaggaat
3001 tactgaggcc tttggagttc ccattaacca aattcaaatt cacaaatctg gagagttttg
3061 ccgcttgcgg tttccaaaac caatcaggcc agacgtgagt ggaatgatct tggaagaggg
3121 tgcccctgaa ggcactgttg tttccattct catcaagagg acgacagggg aactgatgcc
3181 tctcgcagtc agaatgggaa ctcatgccac aatgaaaatc caaggtagaa cggtgggcgg
3241 tcaaatgggc atgcttctca ctggctcaaa cgccaaaagc atggacctag gcacaacacc
3301 aggtgactgt gggtgcccat acatatacaa aaggggcaat gacttcgtgg tcattggggt
3361 gcacactgca gcagcccgtg gaggtaacac ggtcatatgt gccacacagg ggagtgaagg
3421 cgaagccacc ctcgaaggag gtgacaacaa gggcacctat tgtggagccc ccatcttggg
3481 tcctggcaat gcaccaaaat tgagcacaaa aacaaaattc tggagatctt ctaacgcgcc
3541 gctcccgcca ggcacctacg aaccagcata ccttggtgga aaagacccgc gtgtgaaggg
3601 aggcccatct ctacaacagg ttatgagaga ccaactcaaa ccttttacag agcccagagg
3661 gaagccacca aaaccaagtg tcctagaatc agcaaagaag accatcatta atgttctgga
3721 acaaaccatt gacccccctg aaaagtggtc atatgcccaa gcttgtgcat ccctcgacaa
3781 gacaacctcc agtggatacc cgcatcacgt ccggaagaat gactactgga gtggtgaatc
3841 cttcacgggg aaacttgcag accaggcctc aaaagcaaat ctcatgtatg aggaaggtaa
3901 gcacatgcaa ccagtttaca ccgcagcact caaagacgag ctcgtgaaaa ctgacaaaat
3961 ttatggcaag atcaagaaaa gactcctgtg gggctctgac ctatccacca tgattcgatg
4021 cgccagggca tttggtggcc tcatggacga gctcaaagca aattgtatca cactccctat
4081 cagagttggt atgaacatga atgaagatgg tcccataata tttgaaaagc actccaggta
4141 caggtaccac tatgatgctg attattcccg ctgggattcc acacaacagc gggcagtgct
4201 ggaagcggca cttgaaatca tggtgagatt ttctgctgag ccacagttgg cacaaatagt
4261 ggcaggggac ctgctatcac caagtgtggt tgatgtgggc gatttcaaaa ttactattaa
4321 tgaaggccta ccatctggcg tgccttgcac ttcacaatgg aattctattg cccactggtt
4381 actcacccta tgtgccctgt ctgaagtgac aggactaggc cctgacatca tacaagccaa
4441 ctccatgtac tctttctatg gtgatgatga gattgtgagc acagacataa aattagaccc
4501 agagaaattg actgcaaaac tcaaagaata tggtcttaaa cccacccggc ctgacaagac
4561 tgaggggcca ctggtaatta gtgaggacct gaatgggttg actttcctcc gccgaacagt
4621 cacccgcgat ccagcgggtt ggtttggaaa gttggaccaa aactccatcc tcagacagct
4681 gtactggaca aggggaccca accatgaaga ccccagtgag actatgatac cacacgcaca
4741 gagacctgtg cagctcatgg cattgctagg agaatcctcc ctacatggac cctcatttta
4801 cagcaaggtt agcaaactgg ttatatctga acttaaagag ggaggaatgg atttttatgt
4861 gcccagacaa gagtcaatgt tcaggtggat gaggttctca gatctaagca catgggaggg
4921 cgatcgcaat ctggctccca gttttgtgaa tgaagatggc gtcgaatgac gccgctccat
4981 ctaatgatgg tgctgctggt ctcgtaccag agggcaataa cgagaccctt cccctagaac
5041 cagttgcggg cgcagccata gccgcacccg tcactggcca aaataatata attgacccct
5101 ggattagaac aaattttgtg caagcaccaa atggagagtt cacagtgtca cccagaaact
5161 ctcctggaga aattttacta aacctagagt tgggccctga tctgaaccct tatttggctc
5221 atttgtcaag gatgtataat ggatatgctg gtggagttga agtccaggtt ctcctggcag
5281 ggaacgcgtt cactgccggg aagatcctct tcgccgctgt cccgccaaat tttccggtgg
5341 aattcttaag cccagcccag attacaatgc tcccacatat aatagtagat gttaggactc
5401 ttgaaccaat tatgatccca ttacctgatg ttaggaatac attcttccac tataataatc
5461 agcccaacag ccgcatgaga ttagtggcta tgctctacac cccccttaga tctaatggct
5521 caggtgatga tgttttcact gtttcttgca gggttttgac taggcctacc cctgattttg
5581 agttcactta tctagtgcca ccctctgtcg aatctaagac taaacccttt tctttaccca
5641 ttctaaccct ttctgagctc acaaattcga ggttcccggt ccccatcgat tcgcttttca
5701 ccgcccaaaa taatgttttg caggtgcagt gtcaaaatgg caggtgcaca cttgacggtg
5761 agctacaagg cacaacccag ttgctcccat ctggcatctg tgcgttcagg gggcgggtga
5821 cagcagaagc tgacaatcct gacaagtggc acatgcaact gcaaaacctt aatggcacaa
5881 catatgaccc aactgatgat gtgccagccc cactgggtac acctgacttc aagggcgtcg
5941 tgtttgggat ggcaagccaa agaaatgtgg gtaacgacgc gcccggctca accaggtccc
6001 atgaggcggt gatttcaacc tacagcccca gatttgttcc taaattaggc tctgtcaatt
6061 tcaaaagcaa tgatgatgat ttccaattgc agccaacaag attcacacca gtgggcatta
6121 atgatgatgg caaccaacca ttcagacaat gggaattacc agattattca ggagtgctta
6181 ccttgaatat gaaccttgcc ccccctgttg ctccaaattt ccctggcgaa caattactat
6241 tcttcagatc ttctgtgcca tgttcaggag gttacaacca aggtattata gattgcctta
6301 tcccccaaga atggatccaa cacttctacc aggaatcagc accttctcag tcagaagtgg
6361 ccctaatcag gtacgtcaac cccgacacgg gtcgtacact gtttgaggca aaattgcata
6421 ggtcaggcta tatcactgtg gctcattctg gagactatcc tcttgttgtt ccggctaatg
6481 gatactttag atttgactct tgggtaaatc agttttactc actcgcccca atgggaactg
6541 ggaatgggcg aaggagggct cagtaatggc tggagctttc attgcaggat tggcgggtga
6601 catgctcacg tcatccgtgg gctccctggt gaacgcaggg gcaaacgcca tcaaccaaaa
6661 gatagacttt gaaaacaaca aacaactcca gtctgcttcc tttcaacatg ataaagagat
6721 gctccaagcg caggtgaacg caaccaagca gctgcaatct gagatgatag ccctaaaaca
6781 gggggttttg gccgcaggcg gcttttcccc cactgatgca gcgagggggg ccatcggtgc
6841 acccatgaca aaggtgcttg actggtctgg cactcgatac tgggctccca attccacaaa
6901 gacaactggt tattcggggc aattcacctc ttcacctgtg cacatgccca gcccgagtgt
6961 cccacaatca aaacccgcaa agcccaagtc tctaggttct tcttcttctt ctagtagtgt
7021 ttacagtatg tctacccaat taacttctct aatatctggc tcttctagta atgcttcttc
7081 tgcttctaca aaattgacaa atttgagctc cggctcttct caaaacagaa cagcagagtg
7141 ggtgaaccaa cagagaagtc tcagcccttt catgagtggc gcactcaata tctcgcatgt
7201 cacgccacct tcaagcaggg cctccagttc tgggacggtc tcaaccgtgc ccaaggaagt
7261 tttggactcc tggaca
//