Typing tool
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Typing tool
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Complete norovirus genomes
| PX700450 | GII.17 | |
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| GII.P17 |
ORF1: 1..4992
ORF2: 4973..6589
ORF3: 6589..7326
LOCUS PX700450 7326 bp RNA linear VRL 04-MAR-2026
DEFINITION Norovirus GII isolate 2414YC04 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION PX700450
VERSION PX700450.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7326)
AUTHORS Jin,m., yin,a. and yang,s.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2025) National Key Laboratory of Infectious
Disease Source Tracing, Early Warning and Intelligent
Decision-making, Institute of Viral Disease Control and Prevention,
China CDC, No. 155, Changbai Road, Changping District, Beijing
102206, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7326
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="2414YC04"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Beijing,Changping"
/collection_date="Dec-2024"
/note="genotype: GII.17[P17]"
gene <1..4992
/gene="ORF1"
CDS <1..4992
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="YCB08069.1"
/translation="ALGARSKLPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPK
VTYKVGEGVSGLPDLTTVAQPDAQSTAYSVPPLSQREVGEAREPLPGSILEMWDGEIY
HYGLYVERGHVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETF
PYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKA
ANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWT
PPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLR
ACKDLGSYGLEILKLVIKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDK
DALATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQ
RPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLW
DDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYV
NFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKS
GNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAA
ENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVV
EKVQNAAVQTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMN
ISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAF
SSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKI
RQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFE
APPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRL
RFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGG
QMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGS
EGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDP
RVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQA
CASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKD
ELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCVTLPIRVGMNMNEDG
PIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQKVAEDLLSPS
VVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFY
GDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDP
AGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSK
VSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..882
/gene="ORF1"
/product="p48"
mat_peptide 883..1980
/gene="ORF1"
/product="NTPase"
mat_peptide 1981..2517
/gene="ORF1"
/product="p22"
mat_peptide 2518..2916
/gene="ORF1"
/product="VPg"
mat_peptide 2917..3459
/gene="ORF1"
/product="Pro"
mat_peptide 3460..4989
/gene="ORF1"
/product="RdRp"
gene 4973..6589
/gene="ORF2"
CDS 4973..6589
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YCB08070.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6589..>7326
/gene="ORF3"
CDS 6589..>7326
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YCB08071.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSPSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQP"
ORIGIN
1 gccctcgggg cgcggtctaa gctgccgccc ccgggagaaa caaaacaaac actaagacca
61 ccaaggccgc cgaccccgga attggtgaag aagatacccc cacccccccc caatggcgag
121 gatgaaccaa aggtaacgta taaggtggga gaaggtgtgt ctgggctgcc cgacttaaca
181 accgtggcac aacctgacgc acagagcaca gcctatagtg tccccccact tagccagaga
241 gaggtcggcg aagctagaga accgttgcct ggctccattc tggaaatgtg ggatggtgag
301 atctaccact atgggctgta tgttgagcgg gggcatgtgc tgggagtgca caaaccacct
361 gctgcaataa gccttgccaa aattgagtta acaccgctgt ctctctactg gagagtggtc
421 tacactcccc agtacttgat agctccagag accctcaaga atttaaatgg agagactttc
481 ccatacacgg cctttgacaa caactgttat gccttctgtt gttgggttct ggacctcaac
541 gactcctggc ttagcagaag aatggtccaa agaacaaccg gattcttcag accgtatcag
601 gactggaaca gaaaaccctt accaaccatg gatgaaccaa aaatcaagaa ggccgcgaat
661 gctgttctgt gtgctctctc ctcactcttc actaggccca tcaaagatgt cattggaaag
721 cttaaaccac taaacattat gaacatactg gcaacttgtg attggacttt tgcgggcata
781 gtggaatcca tgatccttct tgctgaactc tttggggtgt tctggacgcc cccagatgtg
841 tctgcaataa ttgctccctt actcggtgac tacgagatgc aaggccccga agacctggcc
901 gtggaacttg tgcccgtggt aatgggagga ataggtttgg tgttaggatt caccaaggaa
961 aagatcggca agatgctttc atcagctgca accacactca gggcctgtaa ggatctagga
1021 tcttatgggt tggagatact caaactggtc ataaagtggt tcttccccaa gaaggaggag
1081 gccaacgagt tagccatggt gagggccatt gaggatgcag ttctggattt ggaggcaata
1141 gaaaacaacc acatgaccac tctccttaag gacaaagacg ccctggccac atacatgagg
1201 actcttgact tggaagaaga aaaagcaagg aaactgtctt ccaaatcggc gtcacctgac
1261 atcgtgggca cagtaaacgc attattggca agaatagcag ccgccaggtc actggtccac
1321 aaggctaagg aggagctctc gagcagacag agacctgttg ttgttatgat atcaggtagg
1381 ccaggtatag gaaagaccca tctggccaga gagctagcca agaaggttgc gtcaacactg
1441 tcaggcgacc aaaggattgg actgataccc agaaatggcg tcgaccattg ggacgcctac
1501 aaaggagagc gggtggttct gtgggatgac tatggcatga gcaaccctat acaggacgca
1561 ctgaggctcc aagaattggc tgacacctgt cctctgaccc taaattgtga cagaattgaa
1621 aacaaaggaa aagtgttcga cagtgacgcc ataatcataa cgaccaacct tgcaaaccca
1681 gcaccattgg attacgtcaa ctttgaggct tgttccagac gcatagactt cttggtgtat
1741 gcagacgcac ctgacatcga gaaggctaag cgtgacttcc ctggccaacc agatatgtgg
1801 aaagaccatt acagaccaga cttctcacac attaaacttc agctcgcacc acagggaggc
1861 tttgataaaa gtggcaacac cccacatggc aaaggtgtgg ttaagtctct gacgattggt
1921 tctctgatcg ccagggcttc tggcttgctc catgagagaa tggatgaatt cgagctccaa
1981 ggccccaact tgccaacctt caatttcgac cgtaacaaag tcgccgcctt cagacaattg
2041 gcagctgaaa acaaatacgg tcttatggac acactgaggg tcggcaacca actgaaaagc
2101 gtcaaaaccc tggatgagct gaagcaggct ataaagaaca tcaccatcaa gaagtgccag
2161 atagtgtaca atggatgcac ctacaccatg gaatctgatg ggaggaacaa ggttgtggtt
2221 gaaaaggttc aaaatgcagc agtccaaacc aacaatgaac ttgcaggagc actccaccac
2281 ctgagatctg caagaataag gtattatgtc aaatgtttcc aagaagctat ttactctata
2341 ctccaaattg ctggtgcagc cttcgtcacc acacgcatcg tgaggcgcat gaacatctca
2401 aacctctggt cgaagccacc cgtcgaagag ggtgatgaac ctgaagacaa aggggggtgc
2461 cccaagccca gggatgaaga tgacctcact attgactcca aagacattaa agcagaaggt
2521 aagaagggca agaacaaatc tggccggggc aagaaacaca cagctttctc atccaagggc
2581 ctcagtgatg aagagtacga tgagtacaag agaatcaggg aggagagaaa tggcaagtat
2641 tcaatagaag aatacctcca ggatagggat agatactatg aagagcttgc cattgctaag
2701 gccactgagg aagacttctg tgaagaggag gaaatcaaga ttcgccagag aatcttccgg
2761 cccaccagga agcagcggaa agaggaaaga gccacgcttg ggctcgtcac aggatcggaa
2821 atcagaaaga ggaacccaga tgattttaag ccaaaaggaa aattgtgggc tgatgacaac
2881 aggagtgtgg actacaatga gaggatagat tttgaggctc ccccaagtgt ttggtctagg
2941 atagtcaact ttggtacagg gtggggattc tgggtctccc caagtctctt tataacttca
3001 acacatgtca taccaaaagg aatcactgag gcctttggag ttcccattaa ccaaattcaa
3061 attcacaaat ctggagagtt ttgccgcttg cggtttccaa aaccaatcag gccagacgtg
3121 agtggaatga tcttggaaga gggtgcccct gaaggcactg ttgtttccat tctcatcaag
3181 aggacgacag gggaactgat gcctctcgca gtcagaatgg gaactcatgc cacaatgaaa
3241 atccaaggta gaacggtggg cggtcaaatg ggcatgcttc tcactggctc aaacgccaaa
3301 agcatggacc taggcacaac accaggtgac tgtgggtgtc catacatata caaaaggggc
3361 aatgacttcg tggtcattgg ggtgcacact gcagcagccc gtggaggtaa cacggtcata
3421 tgtgccacac aggggagtga aggcgaagcc accctcgaag gaggtgacaa caagggcacc
3481 tattgtggag cccccatctt gggtcctggc aacgcaccaa aattgagcac aaaaacaaaa
3541 ttctggagat cttctaacgc gccgctcccg ccaggcacct atgaaccagc ataccttggt
3601 ggaaaagacc cgcgtgtgaa gggaggccca tctctacaac aggttatgag agaccaactc
3661 aaacctttta cagagcccag agggaaacca ccaaaaccaa gtgtcctaga atcagcaaag
3721 aagaccatca ttaatgttct ggaacaaacc attgaccccc ctgaaaagtg gtcatatgcc
3781 caagcttgtg catcccttga caagacaacc tccagtggat acccgcatca cgtccggaag
3841 aatgactact ggagtggtga atctttcacg gggaaacttg cagaccaggc ctcaaaagca
3901 aatctcatgt atgaggaagg taagcacatg caaccagttt acaccgcagc actcaaagac
3961 gagctcgtga aaactgacaa aatttatggc aagatcaaga aaagactcct gtggggctct
4021 gacctatcca ccatgattcg atgcgccagg gcatttggtg gcctcatgga cgagctcaaa
4081 gcaaattgtg tcacactccc tatcagagtt ggtatgaaca tgaatgaaga tggtcccata
4141 atatttgaaa agcactccag gtacaggtac cactatgatg ctgattactc ccgctgggat
4201 tccacacaac agcgggcagt gctggaagcg gcacttgaaa tcatggtgag attttctgct
4261 gagccacaat tggcacaaaa agtggcagag gacctgctat caccaagtgt ggttgatgtg
4321 ggcgatttca aaattactat taatgaaggc ctaccatctg gcgtgccttg cacttcacaa
4381 tggaattcta ttgcccactg gttactcacc ctatgtgccc tgtctgaagt gacaggacta
4441 ggccctgaca tcatacaagc caactccatg tactctttct atggtgatga tgagatagtg
4501 agcacagaca taaaattaga cccagagaaa ttgactgcaa aactcaaaga atatggtctt
4561 aaacccaccc ggcctgacaa gactgagggg ccactggtaa ttagtgagga cctgaatggg
4621 ttgactttcc tccgccgaac agtcacccgc gatccagcgg gttggtttgg aaagttggac
4681 caaaactcca tcctcagaca gctgtactgg acaaggggac ccaaccatga agaccccagt
4741 gagactatga taccacacgc acagagacct gtgcagctca tggcattgct aggagaatcc
4801 tccctacatg gaccctcatt ctacagcaaa gttagcaagc tggttatatc tgaacttaaa
4861 gagggaggaa tggattttta tgtgcccaga caagagtcaa tgttcaggtg gatgaggttc
4921 tcagatctaa gcacatggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat
4981 ggcgtcgaat gacgccgctc catctaatga tggtgctgct ggtctcgtac cagagggcaa
5041 taacgagacc cttcccctag aaccagttgc gggcgcagcc atagccgcac ccgtcactgg
5101 ccaaaataat ataattgacc cctggattag aacaaatttt gtgcaagcac caaatggaga
5161 gttcacagtg tcacccagaa actctcctgg agaaatttta ctaaacctag agttgggccc
5221 tgatctgaac ccttatttgg ctcatttgtc aaggatgtat aatggatatg ctggtggggt
5281 tgaagtccag gttctcctgg cagggaacgc gttcactgcc gggaagatcc tcttcgccgc
5341 tgtcccgcca aattttccgg tggaattctt aagcccagcc cagattacaa tgctcccaca
5401 tataatagta gatgttagga ctcttgaacc aattatgatc ccattacctg atgttaggaa
5461 tacattcttc cattataata accagcccaa cagccgcatg agattagtgg ctatgctcta
5521 cacccccctt agatctaatg gctcaggtga tgatgttttc actgtttctt gtagggtttt
5581 gactaggcct actcctgatt ttgagtttac ttatctagtg ccaccctctg ttgaatctaa
5641 gactaaaccc ttttctttac ccattctgac cctttctgag ctcacaaatt cgaggttccc
5701 ggtccccatc gattcgcttt tcaccgccca aaataatgtg ttgcaggtgc agtgtcaaaa
5761 tggcaggtgc acacttgacg gtgagctaca aggcacaacc cagttgctcc catctggcat
5821 ctgtgcgttc aggggacggg tgacagcaga aactgacaac cctgacaagt ggcacatgca
5881 actgcaaaac cttaatggca caacatatga cccaactgat gatgtgccag ctccactggg
5941 tacacctgac ttcaagggcg tcgtgtttgg gatggcaagc caaagaaatg tgggtaacga
6001 cgcgcccggc tcaaccaggt cccatgaggc ggtgatttca acctacagcc ccagatttgt
6061 tcctaaatta ggctctgtca atttcaaaag caatgacgat gatttccaat tgcagccaac
6121 aagattcaca ccagtgggca ttaatgatga tggcaaccaa ccattcagac aatgggaact
6181 accagattat tcaggggtgc ttaccttgaa tatgaacctt gccccccctg ttgctccaaa
6241 tttccccggc gaacaattac tattcttcag atcttctgtg ccatgttcag gaggttacaa
6301 ccaaggcatt atagattgcc ttatccccca agaatggatc caacatttct accaggaatc
6361 agcaccttct cagtcagaag tggccctaat caggtacgtc aaccccgaca cgggtcgtac
6421 actgtttgag gcaaaattgc ataggtcagg ctatatcact gtggctcatt ctggagacta
6481 tcctcttgtt gttccggcta atggatactt tagatttgac tcttgggtaa atcagtttta
6541 ctcactcgcc ccaatgggaa ctgggaatgg gcgaaggagg gctcagtaat ggctggagct
6601 ttcattgcag gattggcggg tgacatgctc acgtcatccg tgggctccct ggtgaacgca
6661 ggggcaaacg ccatcaacca aaagatagac tttgaaaaca acaaacaact ccagtctgct
6721 tcctttcaac atgataaaga gatgctccaa gcgcaggtga acgcaaccaa gcagctgcaa
6781 tctgagatga tagccctaaa acagggggtt ttggccgcag gcggcttttc ccccactgat
6841 gcagcgaggg gggccatcgg tgcacccatg acaaaggtgc ttgactggtc tggcactcga
6901 tactgggctc ccaattccac aaagacaact ggttattcgg ggcaattcac ctcttcacct
6961 gtgcatatgc ccagcccgag tgtcccacaa tcaaaacccg caaagcccaa gtctctaggt
7021 tctccttctt cttctagtag tgtttacagt atgtctaccc aattaacttc tctaacatct
7081 ggctcttcta gtaatgcttc ttctgcttct acaaaattga caaatttgag ctccggctct
7141 tctcaaaaca gaacagcaga gtgggtgaac caacagagaa gtctcagccc tttcatgagt
7201 ggcgcactca atatctcgca tgtcacgcca ccttcaagta gggcctccag ttctgggacg
7261 gtctcaaccg tgcccaagga agttttggac tcctggacat ctgcattcaa cacacgcaga
7321 cagccg
//