Typing tool
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Typing tool
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Complete norovirus genomes
| PX700449 | GII.17 | |
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| GII.P17 |
ORF1: 1..4993
ORF2: 4974..6590
ORF3: 6590..7330
LOCUS PX700449 7330 bp RNA linear VRL 04-MAR-2026
DEFINITION Norovirus GII isolate 2414YC03 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION PX700449
VERSION PX700449.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7330)
AUTHORS Jin,m., yin,a. and yang,s.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-2025) National Key Laboratory of Infectious
Disease Source Tracing, Early Warning and Intelligent
Decision-making, Institute of Viral Disease Control and Prevention,
China CDC, No. 155, Changbai Road, Changping District, Beijing
102206, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7330
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="2414YC03"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Beijing,Changping"
/collection_date="Dec-2024"
/note="genotype: GII.17[P17]"
gene <1..4993
/gene="ORF1"
CDS <1..4993
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="YCB08066.1"
/translation="ALGARSKQPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPK
VTYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIY
HYGLYVERGHVLGVHKPPAAISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETF
PYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKA
ANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWT
PPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLR
ACKDLGSYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDK
DALATYMRTLDLEEEKARKLSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQ
RPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLW
DDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYV
NFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKS
GNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAA
ENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVV
EKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMN
ISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAF
SSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKI
RQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFE
APPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRL
RFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGG
QMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGS
EGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDP
RVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQA
CASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKD
ELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDG
PIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPS
VVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFY
GDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDP
AGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSK
VSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..883
/gene="ORF1"
/product="p48"
mat_peptide 884..1981
/gene="ORF1"
/product="NTPase"
mat_peptide 1982..2518
/gene="ORF1"
/product="p22"
mat_peptide 2519..2917
/gene="ORF1"
/product="VPg"
mat_peptide 2918..3460
/gene="ORF1"
/product="Pro"
mat_peptide 3461..4990
/gene="ORF1"
/product="RdRp"
gene 4974..6590
/gene="ORF2"
CDS 4974..6590
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YCB08067.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6590..>7330
/gene="ORF3"
CDS 6590..>7330
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YCB08068.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSPSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPL"
ORIGIN
1 agccctcggg gcgcggtcta agcagccgcc cccgggagaa acaaaacaaa cactaagacc
61 accaaggccg ccgacaccgg aattggtgaa gaagataccc ccaccccccc ccaatggcga
121 ggatgaacca aaggtaacgt ataaggtggg agaaggtgtg tctgggctgc ccgacttaac
181 aaccgtggca caacctgacg cacagaacac agcctatagt gtccccccac ttagccagag
241 agaggtcggc gaagctagag aaccgttgcc tggctccatt ctggaaatgt gggatggtga
301 gatctaccac tatgggctgt atgttgagcg ggggcatgtg ctgggagtgc acaaaccacc
361 tgctgcaata agccttgcca aaattgagtt aacaccgctg tctctctact ggagagtggt
421 ctacactccc cagtacttga tagctccaga gaccctcaag aatttaaatg gagagacttt
481 cccatacacg gcctttgaca acaactgtta tgccttctgt tgttgggttc tagacctcaa
541 cgactcctgg cttagcagaa gaatggtcca aagaacaacc ggattcttca gaccgtatca
601 ggactggaac agaaaaccct taccaaccat ggatgaacca aaaatcaaga aggccgcgaa
661 tgctgttctg tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa
721 gcttaaacca ctaaacatta tgaacatact ggcaacttgt gattggactt ttgcgggcat
781 agtggaatcc atgatccttc ttgctgaact ctttggggtg ttctggacgc ccccagatgt
841 gtctgcaata attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
901 cgtggaactt gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga
961 aaagatcggc aagatgcttt catcagctgc aaccacactc agggcctgta aggatctagg
1021 atcttatggg ttggagatac tcaaactggt catgaagtgg ttcttcccca agaaggagga
1081 ggccaacgag ttagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat
1141 agaaaacaac cacatgacca ctctccttaa ggacaaagac gccctggcca catacatgag
1201 gactcttgac ttggaagaag aaaaagcaag gaaactatct tccaaatcgg cgtcacctga
1261 catcgtgggc acagtaaacg cattattggc aagaatagca gccgccaggt cactggtcca
1321 caaggctaag gaggagctct cgagcagaca gagacctgtt gttgtaatga tatcaggtag
1381 gccaggtata ggaaagaccc atctggccag agagctagcc aagaaggttg cgtcaacact
1441 gtcaggcgac caaaggattg gactgatacc cagaaatggc gtcgaccatt gggacgccta
1501 caaaggagag cgggtggttc tgtgggatga ctatggcatg agcaacccta tacaggacgc
1561 actgaggctc caagaattgg ctgacacctg tcctctgacc ctaaattgtg acagaattga
1621 aaacaaagga aaagtgttcg acagcgacgc cataatcata acgaccaacc ttgcaaaccc
1681 agcaccattg gattatgtca actttgaggc ttgttccaga cgcatagact tcttggtgta
1741 tgcagacgca cctgacatcg agaaggctaa gcgtgacttt cctggccaac cagatatgtg
1801 gaaagaccat tacagaccag acttctcaca cattaaactt cagctcgcac cacagggagg
1861 ctttgataag agtggcaaca ccccacatgg caaaggcgtg gttaagtctc tgacgattgg
1921 ctctctgatc gccagggctt ctggcttgct ccatgagaga atggatgaat tcgagctcca
1981 aggccccaac ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt
2041 ggcagctgaa aacaaatacg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2101 tgtcaaaacc ctggatgagc tgaagcaggc cataaagaac atcactatca agaagtgcca
2161 gatagtgtac aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt
2221 tgaaaaagtt caaaatgcaa cagtccaaac caacaatgaa cttgcaggag cactccacca
2281 cctgagatct gcaagaataa ggtattatgt caaatgtttc caagaagcta tttactctat
2341 actccaaatt gctggtgcag ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc
2401 aaacctctgg tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg
2461 ccccaagccc agggatgaag atgacctcac tattgactcc aaagacatta aagcagaagg
2521 taagaagggc aagaacaaat ctggccgggg caagaaacac acagctttct catccaaggg
2581 cctcagtgat gaagagtacg atgagtacaa gagaatcagg gaggagagaa atggcaagta
2641 ctcaatagaa gaatacctcc aggataggga tagatactat gaagagcttg ccattgctaa
2701 ggccactgag gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg
2761 gcccaccagg aagcagcgga aagaggaaag agccacgctt gggctcgtca caggatcgga
2821 aatcagaaag aggaacccag atgattttaa gccaaaagga aaattgtggg ctgatgacaa
2881 caggagtgtg gactacaatg agaggataga ttttgaggct cccccaagtg tttggtctag
2941 gatagtcaac tttggtacag gatggggatt ctgggtctcc ccaagtctct ttataacttc
3001 aacacatgtc ataccaaaag gaattactga ggcctttgga gttcccatta accaaattca
3061 aattcacaaa tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt
3121 gagtggaatg atcttggaag agggtgcccc tgaaggcact gttgtttcca ttctcatcaa
3181 gaggacgaca ggggaactga tgcctctcgc agtcagaatg ggaactcatg ccacaatgaa
3241 aatccaaggt agaacggtgg gcggtcaaat gggcatgctt ctcactggct caaacgccaa
3301 aagcatggac ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg
3361 caatgacttc gtggtcattg gggtgcacac tgcagcagcc cgtggaggta acacggtcat
3421 atgtgccaca caggggagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac
3481 ctattgtgga gcccccatct tgggtcctgg caacgcacca aaattgagca caaaaacaaa
3541 attctggaga tcttctaacg cgccgctccc gccaggcacc tacgaaccag cataccttgg
3601 tggaaaagac ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact
3661 caaacctttt acagagccca gagggaagcc accaaaacca agtgtcctag aatcagcaaa
3721 gaagaccatc attaatgttc tggaacaaac cattgacccc cctgaaaagt ggtcatatgc
3781 ccaagcttgt gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa
3841 gaatgactac tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc
3901 aaatctcatg tatgaggaag gtaagcacat gcaaccagtt tacaccgcag cactcaaaga
3961 cgagctcgtg aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc
4021 tgacctatcc accatgattc gatgcgccag ggcatttggt ggcctcatgg acgagctcaa
4081 agcaaattgt atcacactcc ctatcagagt tggtatgaac atgaatgaag atggtcccat
4141 aatatttgaa aagcactcca ggtacaggta ccactatgat gctgattatt cccgctggga
4201 ttccacacaa cagcgggcag tgctggaagc ggcacttgaa atcatggtga gattttctgc
4261 tgagccacag ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt
4321 gggcgatttc aaaattacta ttaatgaagg cctaccatct ggcgtgcctt gcacttcaca
4381 atggaattct attgcccact ggttactcac cctatgtgcc ctgtctgaag tgacaggact
4441 aggccctgac atcatacagg ccaactccat gtactctttc tatggtgatg atgagattgt
4501 gagcacagac ataaaattag acccagagaa attgactgca aaactcaaag aatatggtct
4561 taaacccacc cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg
4621 gttgactttc ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga
4681 ccaaaactcc atcctcagac agctgtactg gacaagggga cccaaccatg aagaccccag
4741 tgagactatg ataccacacg cacagagacc tgtgcagctc atggcattgc taggagaatc
4801 ctccctacat ggaccctcat tttacagcaa ggttagcaaa ctggttatat ctgaacttaa
4861 agagggagga atggattttt atgtgcccag gcaagagtca atgttcaggt ggatgaggtt
4921 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
4981 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5041 ataacgagac ccttccccta gaaccagttg cgggcgcagc catagccgca cccgtcactg
5101 gccaaaataa tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5161 agttcacagt gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc
5221 ctgatctgaa cccttatttg gctcatttgt caaggatgta taatggatat gctggtggag
5281 ttgaagtcca ggttctcctg gcagggaacg cgttcactgc cgggaagatc ctcttcgccg
5341 ctgtcccgcc aaattttccg gtggaattct taagcccagc ccagattaca atgctcccac
5401 atataatagt agatgttagg actcttgaac caattatgat cccattacct gatgttagga
5461 atacattctt ccactataat aatcagccca acagccgcat gagattagtg gctatgctct
5521 acacccctct tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt
5581 tgactaggcc tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta
5641 agactaaacc cttttcttta cccattctaa ccctttctga gctcacaaat tcgaggttcc
5701 cggtccccat cgattcgctt ttcaccgccc aaaataatgt tttgcaggtg cagtgtcaaa
5761 atggcaggtg cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca
5821 tctgtgcgtt cagggggcgg gtgacagcag aaactgacaa tcctgacaag tggcacatgc
5881 aactgcaaaa ccttaatggc acaacatatg acccaactga tgatgtgcca gccccactgg
5941 gtacacctga cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg
6001 acgcgcccgg ctcaaccagg tcccatgagg cggtgatttc aacctacagc cccagatttg
6061 ttcctaaatt aggctctgtc aatttcaaaa gcaatgatga tgatttccaa ttgcagccaa
6121 caagattcac accagtgggc attaatgatg atggcaacca accatttaga caatgggaac
6181 taccagatta ttcaggagtg cttaccttga atatgaacct tgccccccct gttgctccaa
6241 atttccctgg cgaacaatta ctattcttca gatcttctgt gccatgttca ggaggttaca
6301 accaaggtat tatagattgc cttatccccc aagaatggat ccaacacttc taccaggaat
6361 cagcaccttc tcagtcagaa gtggccctaa tcaggtacgt caaccccgac acgggtcgta
6421 cactgtttga ggcaaaattg cataggtcag gctatatcac tgtggctcat tctggagatt
6481 atcctcttgt tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt
6541 actcactcgc cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc
6601 tttcattgca ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc
6661 aggggcaaac gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc
6721 ttcctttcaa catgataaag agatgctcca agcgcaggtg aacgcaacca agcagctgca
6781 atctgagatg atagccctaa aacagggggt tttggccgca ggcggctttt cccccactga
6841 tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg
6901 atactgggct cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc
6961 tgtgcacatg cccagcccga gtgtcccaca atcaaaaccc gcaaagccca agtctctagg
7021 ttctccttct tcttctagta gtgtttacag tatgtctacc caattaactt ctctaacatc
7081 tggctcttct agtaatgctt cttctgcttc tacaaaattg acaaatttga gctccggctc
7141 ttctcaaaac agaacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag
7201 tggcgcactc aatatctcgc atgtcacgcc accttcaagt agggcctcca gttctgggac
7261 ggtctcaacc gtgcccaagg aagttttgga ctcctggaca tctgcattca acacacacag
7321 acagccgctc
//