Typing tool
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Typing tool
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Complete norovirus genomes
| PX285875 | GII.17 | |
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| GII.P17 |
ORF1: 1..5095
ORF2: 5076..6692
ORF3: 6692..7471
LOCUS PX285875 7539 bp RNA linear VRL 12-SEP-2025
DEFINITION Norovirus GII isolate 20241224/1A nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION PX285875
VERSION PX285875.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7539)
AUTHORS Ma,J., Li,C. and Huo,Y.
TITLE Direct Submission
JOURNAL Submitted (07-SEP-2025) Translational medicine center, The sixth
people hospital of Zhengzhou, Jingguang south road, Zhengzhou,
Henan 45000, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7539
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="20241224/1A"
/isolation_source="anal swab"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China: Henan, Zhengzhou"
/collection_date="2024-12-24"
/note="genotype: GII.P17-GII.17"
gene <1..5095
/gene="ORF1"
CDS <1..5095
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="YAB12380.1"
/translation="NDASVAVAGKNNNNDNVKSSSDSLFSNMTVTLKKALGARSKQPP
PGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVAQPDAQ
NTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLA
KIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLNDSWL
SRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLK
PLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPEDLA
VELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKK
EEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLSSKS
ASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMLSGRPGIGKTHLARELAK
KVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPL
TLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAK
RDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIARASG
LLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDE
LKQAIKNIAIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSA
RIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPAEEGDEPEDKGGCPK
PRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKY
SIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTG
SEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSL
FITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTV
VSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCG
CPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPG
NAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRG
KPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSG
ESFTGKLADQASKANLMYEEGKHIQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLST
MIRCARAFGGLMDELKANCVTLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDST
QQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQ
WNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEY
GLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNH
EDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESM
FRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..985
/gene="ORF1"
/product="p48"
mat_peptide 986..2083
/gene="ORF1"
/product="NTPase"
mat_peptide 2084..2620
/gene="ORF1"
/product="p22"
mat_peptide 2621..3019
/gene="ORF1"
/product="VPg"
mat_peptide 3020..3562
/gene="ORF1"
/product="Pro"
mat_peptide 3563..5092
/gene="ORF1"
/product="RdRp"
gene 5076..6692
/gene="ORF2"
CDS 5076..6692
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="YAB12381.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6692..7471
/gene="ORF3"
CDS 6692..7471
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="YAB12382.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSPSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLSNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHITPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 taacgacgct tccgttgccg ttgctggcaa aaacaacaac aacgacaatg taaaatcttc
61 aagtgacagc ttgttttcta acatgactgt tactcttaag aaagccctcg gggcgcggtc
121 taagcagccg cccccgggag aaacaaaaca aacactaaga ccaccaaggc cgccgacacc
181 ggaattggtg aagaagatac ccccaccccc ccccaatggc gaagatgaac caaaggtaac
241 gtataaggtg ggagaaggtg tgtctgggtt gcccgactta acaaccgtgg cacaacctga
301 cgcacagaac acagcctata gtgtcccccc acttagccag agagaggtcg gcgaagctag
361 agaaccgttg cctggctcca ttctggaaat gtgggatggt gagatctacc actatgggct
421 gtatgttgag cgggggcatg tgctgggagt gcacaaacca cctgctgcaa taagccttgc
481 caaaattgag ttaacaccgc tgtctctcta ctggagagtg gtctacactc cccagtactt
541 gatagctcca gagaccctca agaatttaaa tggagagact ttcccataca cggcctttga
601 caacaactgt tatgccttct gttgttgggt tctggacctc aacgactcct ggcttagcag
661 aagaatggtc caaagaacaa ccggattctt cagaccgtat caggactgga acagaaaacc
721 cttaccaacc atggatgaac caaaaatcaa gaaggccgcg aatgctgttc tgtgtgctct
781 ctcctcactc ttcaccaggc ccatcaaaga tgtcattggg aagcttaaac cactaaacat
841 tatgaacata ctggcaactt gtgattggac ttttgcgggc atagtggaat ccatgatcct
901 tcttgctgaa ctctttgggg tgttctggac gcccccagat gtgtctgcaa taattgctcc
961 cttactcggt gactacgaga tgcaaggccc cgaagacctg gccgtggaac ttgtgcccgt
1021 ggtaatggga ggaataggtt tggtgttagg attcaccaag gaaaagatcg gcaagatgct
1081 ttcatcagct gcaaccacac tcagggcctg taaggatcta ggatcttatg ggttggagat
1141 actcaaactg gtcatgaagt ggttcttccc caagaaggag gaggccaacg agttagccat
1201 ggtgagggcc attgaggatg cagttctgga tttggaggca atagaaaaca accacatgac
1261 cactctcctt aaggacaaag acgccctggc cacatacatg aggactcttg acttggaaga
1321 agaaaaagca aggaaactat cttccaaatc ggcgtcacct gacatcgtgg gcacagtaaa
1381 cgcattattg gcaagaatag cagccgccag gtcactggtc cacaaggcta aggaggagct
1441 ctcgagcaga cagagacctg ttgttgtaat gctatcaggt aggccaggta taggaaagac
1501 ccatctggcc agagagctag ccaagaaggt tgcgtcaaca ctgtcaggag accaaaggat
1561 tggactgata cccagaaatg gcgtcgacca ttgggacgcc tacaaaggag agcgggtggt
1621 tctgtgggat gactatggca tgagcaaccc tatacaggac gcactgaggc tccaagaatt
1681 ggctgacacc tgtcctctga ccctaaattg tgacagaatt gaaaacaaag ggaaagtgtt
1741 cgacagtgac gccataatca taacgaccaa ccttgcaaac ccagcaccat tggattatgt
1801 caactttgag gcttgttcca gacgcataga cttcttggtg tatgcagacg cacctgacat
1861 cgagaaggct aagcgtgact tccctggcca accagatatg tggaaagacc attacagacc
1921 agacttctca cacattaaac ttcagctcgc accacaggga ggctttgata agagtggcaa
1981 caccccacat ggcaaaggtg tggttaagtc tctgacgatt ggttctctga tcgccagggc
2041 ttctggcttg ctccatgaga gaatggatga attcgagctc caaggcccca acttgccaac
2101 cttcaatttc gaccgtaaca aagtcgccgc cttcagacaa ttggcagctg aaaacaaata
2161 cggtcttatg gacacactga gggtcggcaa ccaactgaaa agtgtcaaaa ccctggatga
2221 gctgaagcag gctataaaga acatcgccat caagaagtgc cagatagtgt acaatggatg
2281 cacctacacc atggaatctg atgggaggaa caaggttgtg gttgaaaagg ttcaaaatgc
2341 aacagtccaa accaacaatg aacttgcagg agcactccac cacctgagat ctgcaagaat
2401 aaggtattat gtcaaatgtt tccaagaagc tatttactct atactccaaa ttgctggtgc
2461 agccttcgtc accacacgca tcgtgaggcg catgaacatc tcaaacctct ggtcgaagcc
2521 acccgccgaa gagggtgatg aacctgaaga caaagggggg tgccccaagc ccagggatga
2581 agatgacctc actattgact ccaaagacat taaagcagaa ggtaagaagg gcaagaacaa
2641 atctggccgg ggcaagaaac acacagcttt ctcatccaag ggcctcagtg atgaagagta
2701 cgatgagtac aagagaatca gggaggagag aaatggcaag tactcaatag aagaatacct
2761 ccaggatagg gatagatact atgaagagct tgccattgct aaggccactg aggaagactt
2821 ctgtgaagag gaggaaatca aaattcgcca gagaatcttc cggcccacca ggaagcagcg
2881 gaaagaggaa agagccacgc ttgggctcgt cacaggatcg gaaatcagaa agaggaaccc
2941 agatgatttt aagccaaaag gaaaattgtg ggctgatgac aacaggagtg tggactacaa
3001 tgagaggata gattttgagg ctcccccaag tgtttggtct aggatagtca actttggtac
3061 agggtgggga ttctgggttt ccccaagtct ctttataact tcaacacatg tcataccaaa
3121 aggaatcact gaggcctttg gagttcccat taaccaaatt caaattcaca aatctggaga
3181 gttttgccgc ttgcggtttc caaaaccaat caggccagac gtgagtggaa tgatcttgga
3241 agagggtgcc cctgaaggca ctgttgtttc cattctcatc aagaggacga caggggaact
3301 gatgcctctc gcagtcagaa tgggaactca tgccacaatg aaaatccaag gtagaacggt
3361 gggcggtcaa atgggcatgc ttctcactgg ctcaaacgcc aaaagcatgg acctaggcac
3421 aacaccaggt gactgtgggt gcccatacat atacaaaagg ggcaatgact tcgtggtcat
3481 tggggtgcac actgcagcag cccgtggagg taacacggtc atatgcgcca cacaggggag
3541 tgaaggcgaa gccaccctcg aaggaggtga caacaagggt acctattgtg gagcccccat
3601 cttgggtcct ggcaacgcac caaaattgag cacaaaaaca aaattctgga gatcttctaa
3661 cgcgccgctc ccgccaggca cctatgaacc agcatacctt ggtggaaaag acccgcgtgt
3721 gaagggaggc ccatctctac aacaggttat gagagaccaa ctcaaacctt ttacagagcc
3781 cagagggaag ccaccaaaac caagtgtcct agaatcagca aagaagacca tcattaatgt
3841 tctggaacaa accattgacc cccctgaaaa gtggtcatat gcccaagctt gtgcatccct
3901 cgacaagaca acctccagtg gatacccgca tcacgtccgg aagaatgact actggagtgg
3961 tgaatctttc acggggaaac ttgcagacca ggcctcaaaa gcaaatctca tgtatgagga
4021 aggtaagcac atacaaccag tttacaccgc agcactcaaa gacgagctcg tgaaaactga
4081 caaaatttat ggcaagatca agaaaagact cctgtggggc tctgacctat ccaccatgat
4141 tcgatgcgcc agggcatttg gtggcctcat ggacgagctc aaagcaaatt gtgtcacact
4201 ccctatcaga gttggtatga acatgaatga agatggcccc ataatatttg aaaagcactc
4261 caggtacagg taccactatg atgctgatta ttcccgctgg gattccacac aacagcgggc
4321 agtgctggaa gcggcacttg aaatcatggt gagattttct gctgagccac aattggcaca
4381 aatagtggca gaggacctgc tatcaccaag tgtggttgat gtgggcgatt tcaaaattac
4441 tattaatgaa ggcctaccat ctggcgtgcc ttgcacttca caatggaatt ctattgccca
4501 ctggttactc accctatgtg ccctgtctga agtgacagga ctaggccctg acatcataca
4561 agccaactcc atgtactctt tctatggtga tgatgagata gtgagcacag acataaaatt
4621 agacccagag aaattgactg caaaactcaa agaatatggt cttaaaccca cccggcctga
4681 caagactgag gggccactgg taattagtga ggacctgaat gggttgactt tcctccgccg
4741 aacagtcacc cgcgatccag cgggttggtt tgggaagttg gaccaaaact ccatcctcag
4801 acagctgtac tggacaaggg gacccaacca tgaagacccc agtgagacta tgataccaca
4861 cgcacagaga cctgtgcagc tcatggcatt gctaggagaa tcctccctac atggaccctc
4921 attttacagc aaggttagca agctggttat atctgaactt aaagagggag gaatggattt
4981 ttatgtgccc agacaagagt caatgttcag gtggatgagg ttctcagatc taagcacatg
5041 ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg aatgacgccg
5101 ctccatctaa tgatggtgct gctggtctcg taccagaggg caataacgag acccttcccc
5161 tagaaccagt tgcgggcgca gccatagccg cacccgtcac tggccaaaat aatataattg
5221 acccctggat tagaacaaat tttgtgcaag caccaaatgg agagttcaca gtgtcaccca
5281 gaaactctcc tggagaaatt ttactaaacc tagagttggg ccctgatctg aacccttatt
5341 tggctcattt gtcaaggatg tataatggat atgctggtgg ggttgaagtc caggttctcc
5401 tggcagggaa cgcgttcact gccgggaaga tcctcttcgc cgctgtcccg ccaaattttc
5461 cggtggaatt cttaagccca gcccagatca caatgctccc acatataata gtagatgtta
5521 ggactcttga accaattatg atcccattac ctgatgttag gaatacattc ttccactata
5581 ataatcagcc caacagccgc atgagattag tggctatgct ctacaccccc cttagatcta
5641 atggctcagg tgatgatgtt ttcactgttt cttgcagggt tttgactagg cctactcctg
5701 attttgagtt cacttaccta gtgccaccct ctgttgaatc taagactaaa cccttttctt
5761 tacccattct aaccctttct gagctcacaa attcgaggtt cccggtcccc atcgattcgc
5821 ttttcaccgc ccaaaataat gtgttgcagg tgcagtgtca aaatggcagg tgcacacttg
5881 acggtgagct acaaggcaca acccagttgc tcccatctgg catctgtgcg ttcaggggac
5941 gggtgacagc agaaactgac aaccctgaca agtggcacat gcaactgcaa aaccttaatg
6001 gcacaacata tgacccaact gatgatgtgc cagccccact gggtacacct gacttcaagg
6061 gcgtcgtgtt tgggatggca agccaaagaa atgtgggtaa cgacgcgccc ggctcaacca
6121 ggtctcatga ggcggtgatt tcaacctaca gccccagatt tgttcctaaa ttaggctctg
6181 tcaatttcaa aagcaatgac gatgatttcc aattgcagcc aacaagattc acaccagtgg
6241 gtattaatga tgatggcaac caaccattca gacaatggga actaccagat tattcagggg
6301 tgcttacctt gaatatgaac cttgcccccc ctgttgctcc aaatttcccc ggtgaacaat
6361 tactattctt cagatcttct gtgccatgtt caggaggtta caaccaaggt attatagatt
6421 gccttatccc ccaagaatgg atccaacatt tctaccagga atcagcacct tctcagtcag
6481 aagtggccct aatcaggtac gtcaaccccg acacgggtcg tacactgttt gaggcaaaat
6541 tgcataggtc aggctatatc actgtggctc attctggaga ctatcctctt gttgttccgg
6601 ctaatggata ttttagattt gactcttggg taaatcagtt ttactcactc gccccaatgg
6661 gaactgggaa tgggcgaagg agggctcagt aatggctgga gctttcattg cagggttggc
6721 gggtgacatg ctcacgtcat ccgtgggctc cctggtgaac gcaggggcaa acgccatcaa
6781 ccaaaagata gactttgaaa acaacaaaca actccagtct gcttcctttc aacatgataa
6841 agagatgctc caagcgcagg tgaacgcaac caagcagctg caatctgaga tgatagccct
6901 aaaacagggg gttttggccg caggcggctt ttcccccact gatgcagcga ggggggccat
6961 cggtgcaccc atgacaaagg tgcttgactg gtctggcact cgatattggg ctcccaattc
7021 cacaaagaca actggttatt cggggcaatt cacctcttca cctgtgcaca tgcccagccc
7081 gagtgtccca caatcaaaac ccgcaaagcc caagtctcta ggttctcctt cttcttctag
7141 tagtgtttac agtatgtcta cccaattaac ttctctaaca tctggctctt ctagtaatgc
7201 ttcttctgct tctacaaaat tgtcaaattt gagctccggc tcttctcaaa acagaacagc
7261 agagtgggtg aaccaacaga gaagtctcag ccctttcatg agtggcgcac tcaatatctc
7321 gcatatcacg ccaccttcaa gtagggcctc cagttctggg acggtctcaa ccgtgcccaa
7381 ggaagttttg gactcctgga catctgcatt caacacacgc agacagccgc tcttcgcaca
7441 cctcagagtg aggggggagt cacgtgttta gtgaaaagaa ataattggct ataatatgat
7501 ttctttaaaa ttcaagtttg gctaatttgt atcttttaa
//