Typing tool
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Typing tool
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Complete norovirus genomes
| PV920384 | GII.17 | |
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| GII.P25 |
ORF1: 1..5126
ORF2: 5107..6729
ORF3: 6729..7508
LOCUS PV920384 7576 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-1486-RT-1/2020/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PV920384
VERSION PV920384.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7576)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7576)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7576
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-1486-RT-1/2020/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jan-2020"
/note="genotype: GII.17[P25]"
gene <1..5126
/gene="ORF1"
CDS <1..5126
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XXN27351.1"
/translation="SNDAATATAGKTSTNSEIHNKDVNTTSSLFANMTVGLKRALGAR
PKQPASRVSSPSREGKSETTTRTPPLNKGGRDNTPQIPPPPPNGEDIIIKYTKQDDVI
AGVPTVATVDVPPTHNTAYSVPPLDQREKVEAKEPLTGSIIEMWDGEIYHYGLYVEKG
LVLGVHKPPAAISFARIELTPLSLYWRTVYTPPYLVAPETLRRLHGESFPYNAFDNNC
YSFCCWVLDLNDSWLNRKFVSRTTGFYRPYQEWNRKPLPTMDEGKLKKVANVLLCGLS
GLFTRPIKDLIGKLRPLNILNIITNCDWTFPGVVEALILLAELFGVFWTPPDISTFIA
SLLGDYEMQGPEDIAVEVVPVILGGIGMVLGFTKERIGRLLSSAASSLRACREIGNYG
IEVVKLVMKWFFPTKDETNEMDMVRAIEDAVLDFEAIQNNHMTSLLKDKNSLATFLRE
LDMEEEKARKLSTKSASPDIIGTINALLARIAAARSLVHKAKEEMSSRMRPVVIMISG
RPGIGKTHLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGMSNPV
TDALRLQELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEACSRRI
DFLVYADSPSVDKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGV
MKSLTTHSLIARATGLLHERLDEFDLQGPELPVYNFDQNRVAAFRKLAADNKYGLVET
IKVGNKLKSVRTLEQLKDALKDISIKPCRIIYNSMAYDLDSNGSGRVNVKKVVDHKVQ
TNNELNSALNNLRGARVRYYVKCVQEMVYSLLQIAGAAFVTSRMTRRLNVSGIWARPE
KQVEAVEEPPAPPSEDWTITPSDAIQEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEFK
RIREERQGKYSIEEYLQDRDRYYEELAIAKATEENFCEEEEIKIRQRVFRPTRKQRRE
ERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNEKIDFEAPPSLWSRIVNFGS
GWGFWVSSNLLITSTHVIPPNMTEAFGVPISQIQIHRSGEFCKMRFPKAIRPDVSGMI
LEEGAPEGTVVTILIKRTTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSNAKNM
DLGTIPGDCGCPYVYKRGNDWVVIGVHTAAARGGNTVICATQGPDGEATLEGGDNHGT
YCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRD
QLKPFTAPRGKPPRPATLEAAKETICNVLEQVIEPPQKWSYAQACASLDKTTSSGHPH
HMKKNDNWNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYENIKK
RLLWGSDLGTMIRCARAFGGLMDEMKANCVNLPIRVGMNMNEDGPIIFEKHSKYKYHY
DADYSRWDSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKITINEG
LPSGVPCTSQWNSISHWLITLCAISEVSGLSPDVVQTNSCFSFYGDDEIVSTDIKLDP
MKLTNKLKEYGLIPTRPDKTEGPLIIKESLEGLTFLRRDVCRDPAGWYGKLDQSSIMR
QLYWTKGTNHDDPNETMIPHSQRPIQLMSLLGEAALHGPTFYKKVSKLVITELKEGGM
DFYVPRQEPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide <1..1031
/gene="ORF1"
/product="p48"
mat_peptide 1032..2129
/gene="ORF1"
/product="NTPase"
mat_peptide 2130..2651
/gene="ORF1"
/product="p22"
mat_peptide 2652..3050
/gene="ORF1"
/product="VPg"
mat_peptide 3051..3593
/gene="ORF1"
/product="Pro"
mat_peptide 3594..5123
/gene="ORF1"
/product="RdRp"
gene 5107..6729
/gene="ORF2"
CDS 5107..6729
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27352.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNSETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGSDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6729..7508
/gene="ORF3"
CDS 6729..7508
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27353.1"
/translation="MAGAFIAGLAGDLLTSSVGSLVNAGANAINQKVDFENNKQLQSA
SFQHDKEMLQAQVKATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNVPQSKSAKPRSLAPSSSSSSVYSTYTQST
HLTSGSSSNASSASTRLTNLSSGSSQNRTAEWVNQQRSLSPYMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 cgtctaacga cgctgccact gcgaccgctg gcaaaaccag cacaaacagt gaaattcaca
61 acaaagatgt aaacactaca tcaagcctct tcgccaacat gaccgttggc ttgaagaggg
121 ccctgggggc gaggccaaaa cagcctgcct ccagggtctc ctcccccagt agggagggga
181 agtctgaaac caccactagg actccccccc taaacaaggg aggaagggac aacacccccc
241 aaatacctcc cccgccaccc aatggtgagg acataatcat caaatacacc aaacaagatg
301 atgtgattgc aggggtgccc actgtcgcta cggtggacgt ccccccaaca cacaataccg
361 cctacagtgt cccccccttg gatcagaggg agaaggttga ggcaaaggaa cctctgacag
421 gctcaataat tgagatgtgg gatggtgaaa tttatcacta tgggctctat gttgagaagg
481 gcttggttct tggagtgcac aaacccccgg ctgccataag cttcgcgcgc atagagctca
541 cccccctatc cttatactgg agaacagtct acacaccacc ttacctggta gccccagaaa
601 cacttagaag actccacgga gagtcgttcc catacaatgc atttgacaac aattgctact
661 ccttctgctg ctgggtcttg gacctgaatg attcctggct taacagaaag tttgtttcga
721 ggaccacagg tttctacaga ccctaccaag agtggaacag aaagccccta ccaaccatgg
781 atgagggaaa actcaagaaa gtggccaatg tgctactgtg cggcctctcc ggtcttttca
841 ctagaccaat caaggacctc atagggaaac taagaccatt gaacattctc aacatcatca
901 ccaattgtga ttggactttc cccggagttg tggaagctct catattactt gcagaactct
961 tcggagtctt ctggacacca ccagacattt ccacttttat agcgtcactt ctgggtgatt
1021 atgaaatgca gggccccgag gacattgcag ttgaagttgt gccagtaatt ctcggtggca
1081 taggcatggt actcgggttc accaaagaga gaatcggccg gttgctgagc tctgccgctt
1141 cttcgcttag ggcgtgcaga gagatcggta attacggaat agaggtggtg aagttggtga
1201 tgaaatggtt tttccccacc aaagatgaga caaatgagat ggacatggtg agggcaatag
1261 aggatgccgt gctcgacttt gaggccatac aaaacaacca catgacatca ctactcaaag
1321 acaaaaacag cctggcaacc ttcctcaggg agttagacat ggaagaggag aaagcgcgga
1381 agttatcaac aaagtccgcg tccccagata tcattggaac cataaacgcc cttctagcca
1441 ggattgccgc cgctaggtcc ctagtccaca aggccaaaga agaaatgtca tctaggatgc
1501 gtcccgttgt cattatgatc tctggccgac ccgggatagg aaagacacat ctagcccgcg
1561 acctggccaa gaagatggcg gcgaccctct caggtgacca gagggtaggg ctcgtgccaa
1621 ggaacggtgt cgatcactgg gatgcataca aaggggagag aattgtgctc tgggatgact
1681 atggaatgag caatcctgtg accgacgcgc tgcggctcca agagcttgcc gacacatgcc
1741 ccctgacact caactgtgat aggatagaga ataagggaaa agtctttgac agtgacacta
1801 taattatcac cactaatttg gctaatcctg cccctttaga ttatgtcaat tttgaagctt
1861 gctctcgccg aattgatttc cttgtctatg cggactcccc ctcggttgac aaggcgaaga
1921 gagacttccc cggccaacca gacatgtgga aagacgcatt caaatcagac ttttcacaca
1981 taaaactcca actggcacca caagggggct ttgataagaa cggaaacacc ccccatggga
2041 agggtgtcat gaaatcactg accacacact cccttattgc ccgtgccacg ggtctgttgc
2101 atgagaggtt agatgagttc gacctacagg ggcctgaact acctgtatac aatttcgacc
2161 aaaatagggt ggccgctttt aggaaacttg cagctgacaa caagtacgga ctcgtggaaa
2221 ccataaaagt gggcaacaaa ctgaaaagtg tcagaactct agaacaactc aaggatgccc
2281 taaaagacat aagtatcaag ccttgcagaa taatctacaa ttccatggct tatgatctcg
2341 actcgaatgg gtcaggaagg gtgaacgtca aaaaggttgt ggatcataag gtccaaacta
2401 acaatgaact caactccgcg cttaacaacc tgcgtggcgc tagggtaaga tactatgtca
2461 agtgtgttca agagatggtg tactctctcc tccagatcgc tggcgcggcc ttcgtcactt
2521 caagaatgac gcgaagatta aacgtcagtg gtatctgggc caggccagaa aaacaggtgg
2581 aggcagttga agaaccccca gcccccccat ctgaagattg gaccataacc ccatcagatg
2641 caatccaaga gggtaaaaag ggcaagaaca aaagtggcag aggtaagaaa cacactgcct
2701 tctccagcaa aggcctgagt gatgaggagt atgatgaatt caaaagaatc agggaagaga
2761 ggcagggaaa atattccata gaagaatacc tccaggacag agaccggtac tatgaggaat
2821 tggccatagc caaagcaaca gaagaaaatt tctgtgagga ggaagaaatc aaaattagac
2881 agagggtctt ccgcccaacc agaaaacaac gcagggagga aagagcgacc ctaggactgg
2941 tcacgggtag tgaaatcagg aaaaggaacc ccgatgactt caaaccaaaa ggaaaattgt
3001 gggctgatga tgaccgcagt gtgaattaca atgagaaaat agattttgag gcccctccta
3061 gcctttggtc ccgaatagtg aattttgggt caggctgggg tttctgggtg tcttctaacc
3121 tgttgatcac atcaacacat gtcatccccc cgaacatgac tgaggctttt ggtgtaccaa
3181 taagccagat acaaatacac agaagtggag agttctgcaa aatgaggttc cccaaggcta
3241 taagacctga tgtctcgggc atgatcctgg aggaaggagc acctgaagga acggtggtga
3301 ccatactgat taagagaacc accggtgagc tcatgccatt ggctgcccga atgggcaccc
3361 acgccaccat gaagatacaa gggaaaatgc ttggaggtca aatgggaatg ctcctcacgg
3421 ggtccaacgc caagaacatg gacctcggca ccattcctgg agactgtggt tgcccctatg
3481 tgtacaagag gggtaatgat tgggtggtca taggagtgca caccgcagct gccagaggtg
3541 gcaacaccgt gatctgcgcc acccaggggc cagatggtga ggccacactt gagggaggag
3601 acaaccacgg gacctactgt ggtgcaccaa tacttggacc gggaaatgca ccaaagctca
3661 gcaccaaaac caagttctgg aggtcatcca acgccccact cccacctggc acttatgagc
3721 ctgcttacct aggaggaaag gacccaaggg tcaaaggggg tccgtcatta caacaggtta
3781 tgagggatca gctcaaacct ttcactgccc cccgagggaa accaccgcgg ccagcgacct
3841 tagaggctgc caaagagacc atctgcaatg tgcttgagca agtcattgaa ccgccccaaa
3901 aatggtctta cgctcaggcc tgtgcctcat tggataagac aacatctagt ggccaccctc
3961 accacatgaa aaagaatgac aattggaacg gagagtcttt cactggtgta ttggctgatc
4021 aggcctctaa ggccaatctt atgtttgaac agggaaaaca catgcaaccc gtgtacactg
4081 ctgccctcaa agacgagctc gtcaagacta gtaagatcta tgaaaacatt aagaaaagac
4141 ttctatgggg ctcagatctg ggcacaatga tccgttgtgc tagggcattc ggtggcctca
4201 tggatgagat gaaggcaaat tgtgttaatt taccaatcag agttggcatg aacatgaatg
4261 aagatggacc catcatattt gagaagcatt caaaatacaa ataccactat gatgctgact
4321 attccaggtg ggactcaacc caacagaggc acattcttgg agctgccctt gaaataatgg
4381 ttagattttc agctgaacct gaattggcac aaatagtgtc tgaagacctc ctagccccca
4441 gtgtggtgga cgttggcgac ttcaaaatca ccataaatga aggattgccc tctggagtgc
4501 catgtacatc acagtggaac tcaatttccc actggctcat aacactgtgt gccatatcag
4561 aagtttcagg gctgtcgcca gacgtagtgc aaacaaactc ctgcttctcc ttctacgggg
4621 atgatgagat agtcagcacc gacatcaagt tagatcccat gaagctgacc aacaagttga
4681 aagaatatgg gttgattcca acaaggccag acaagacaga ggggccgctc ataattaaag
4741 agagtcttga gggcctaact ttcctaagga gggacgtgtg tcgagaccca gctggttggt
4801 atggaaaact tgaccaatct tcaatcatga gacaactgta ctggactaag ggaaccaacc
4861 atgatgatcc caatgagaca atgattccac actctcagag acccatacaa ttaatgtcac
4921 tgctagggga ggcagcactg catggtccaa ctttttacaa gaaagtcagc aaattggtca
4981 tcactgagct caaagagggt gggatggatt tctatgtacc aagacaagaa cctatgttca
5041 gatggatgag attctcagac ctcagtactt gggagggcga tcgcaatctt gctcccgaag
5101 gtgtgaatga agatggcgtc gaatgacgcc gctccatcta atgatggtgc tgctggtctc
5161 gtaccagagg gcaacagcga gaccctcccc ctagaaccag ttgcgggcgc agctatagcc
5221 gcacccgtca ctggtcaaaa caacataatt gacccctgga ttagaacaaa ttttgtgcaa
5281 gcaccaaatg gagagttcac agtgtcaccc agaaactctc ctggagaaat tttattaaac
5341 ttagagttgg gccctgattt gaacccttat ttggctcatt tgtcaaggat gtacaatggg
5401 tacgctggtg gagtggaagt tcaggttctc ctggcaggga acgcgttcac tgccggaaag
5461 atcctcttcg ccgccgtccc gccaaatttt ccagtagaat ttttaagccc agcccagatc
5521 acaatgctcc ctcatttaat agtagatgtt aggactcttg aaccaattat gatcccactt
5581 cctgatgtta ggaatacatt cttccattat aataaccagc ctaacagccg catgagatta
5641 gtggctatgc tctatacccc actcagatct aatggctcag gtgatgacgt ctttactgtc
5701 tcttgcaggg ttttgactag gcccactcct gattttgagt tcacttattt agtgccacct
5761 tctgttgaat ctaaaaccaa gcctttttct ttgcctattt taaccctttc tgagctcaca
5821 aattcgaggt tcccagtccc catcgattcg cttttcaccg cccagaataa tgtattgcag
5881 gtacaatgtc aaaatggcag gtgtacactt gatggtgagc tacaaggcac aacccagttg
5941 ctcccatctg gcatctgtgc attcagagga cgggtgacag cacaaattaa ccaacgtgac
6001 aggtggcaca tgcaactgca aaacctcaat ggcacaacat atgacccaac tgatgatgtg
6061 ccagccccgc tgggtacacc tgacttcaag ggcgtcgtgt ttgggatggt aagccaaaga
6121 aatgtgggta gtgatgcgcc tggctcaacc agagcccagc aggcgtgggt ttcaacctat
6181 agcccccaat ttgtccccaa attaggttct gtcaatctta gaattagtga taatgatgac
6241 ttccaattcc agccgacaaa attcacacca gtgggcgtca atgatgacga tgatggccac
6301 ccgttcagac aatgggaatt accaaactat tcaggggagc ttaccttgaa tatgaatctt
6361 gcccccccag ttgctccaaa ttttcctggt gaacaattgt tattcttcag atcttttgtg
6421 ccatgctcag gaggctacaa ccaaggtatc atagattgtc ttattcccca agaatggatc
6481 caacacttct atcaggaatc agcaccctcc cagtcagatg tggccctaat caggtatgtc
6541 aaccctgata cgggacgtac actgtttgaa gcaaaattgc acagatctgg ttacattact
6601 gtggctcact ctggagacta tcctcttgtt gtaccggcta atggacattt tagatttgat
6661 tcttgggtaa atcagtttta ctcactcgcc ccaatgggaa ctgggaatgg gcgaaggagg
6721 gctcagtaat ggctggggct ttcattgcag gattggcagg cgacttgctc acgtcatctg
6781 tgggctccct tgtgaacgca ggggcaaacg ccatcaacca gaaggtagac tttgaaaaca
6841 acaaacaact ccagtctgct tccttccagc atgacaaaga gatgctccaa gcgcaggtga
6901 aggcaaccaa acagctgcaa tctgaaatga tagccttaaa acagggggtt ttggccgcag
6961 gcggcttttc ccccactgat gcagcaaggg gagccattgg tgcacccatg acaaaggtgc
7021 ttgactggtc tggcactcga tactgggcgc ccaactccac aaagacaact ggttattcgg
7081 gacaattcac ctcttcacct gtgcacatgt ctagcccaaa tgttccacaa tcaaaatctg
7141 caaagcctag atctctagct ccttcctctt cttctagcag tgtctatagc acgtatactc
7201 aatctacaca tttaacatct ggctcttcta gtaatgcttc ttctgcctcc acaagattga
7261 caaatttaag ctctggctcc tctcaaaata gaacagcaga gtgggtaaat caacagagaa
7321 gtctcagccc ctacatgagt ggcgcactta acatttcaca tgtcacgcca ccctcaagta
7381 gggcttccag ttctgggacg gtctcgaccg tgcccaagga agttttggac tcctggacgt
7441 ctgcgtttaa cacacacaga cagccgctct tcgcacacct cagagtgagg ggggagtcac
7501 gtgtttagtg aaaagaaata attggccata atgtgatttc tttctgaatt tggctaattt
7561 gtgtctttta aaaaaa
//