Typing tool
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Typing tool
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Complete norovirus genomes
| PV920383 | GII.17 | |
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| GII.P25 |
ORF1: 1..5124
ORF2: 5105..6727
ORF3: 6727..7506
LOCUS PV920383 7574 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-1597-RT-2/2020/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PV920383
VERSION PV920383.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7574)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7574)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7574
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-1597-RT-2/2020/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jan-2020"
/note="genotype: GII.17[P25]"
gene <1..5124
/gene="ORF1"
CDS <1..5124
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27348.1"
/translation="SNDAATATAGKTSTNSEIHNKDVNTTSSLFANMTVGLKRALGAR
PKQPASRVSSPSREGKSETTTRTPPLNKGGRDNTPQIPPPPPNGEDIIIKYTKQDDVI
AGVPTVATVDVPPTHNTAYSVPPLDQREKVEAKEPLTGSIIEMWDGEIYHYGLYVEKG
LVLGVHKPPAAISFARIELTPLSLYWRTVYTPPYLVAPETLRRLHGESFPYNAFDNNC
YSFCCWVLDLNDSWLNRKFVSRTTGFYRPYQEWNRKPLPTMDEGKLKKVANVLLCGLS
GLFTRPIKDLIGKLRPLNILNIITNCDWTFPGVVEALILLAELFGVFWTPPDISTFIA
SLLGDYEMQGPEDIAVEVVPVILGGIGMVLGFTKERIGRLLSSAASSLRACREIGNYG
IEVVKLVMKWFFPTKDETNEMDMVRAIEDAVLDFEAIQNNHMTSLLKDKNSLATFLRE
LDMEEEKARKLSTKSASPDIIGTINALLARIAAARSLVHKAKEEMSSRMRPVVIMISG
RPGIGKTHLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGMSNPV
TDALRLQELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEACSRRI
DFLVYADSPSVDKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGV
MKSLTTHSLIARATGLLHERLDEFDLQGPELPVYNFDQNRVAAFRKLAADNKYGLVET
IKVGNKLKSVRTLEQLKDALKDISIKPCRIIYNSMAYDLDSNGSGRVNVKKVVDHKVQ
TNNELNSALNNLRGARVRYYVKCVQEMVYSLLQIAGAAFVTSRMTRRLNVSGIWARPE
KQVEAVEEPPAPPSEDWTITPSDAIQEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEFK
RIREERQGKYSIEEYLQDRDRYYEELAIAKATEENFCEEEEIKIRQRVFRPTRKQRRE
ERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNEKIDFEAPPSLWSRIVNFGS
GWGFWVSSNLLITSTHVIPPNMTEAFGVPISQIQIHRSGEFCKMRFPKAIRPDVSGMI
LEEGAPEGTVVTILIKRTTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSNAKNM
DLGTIPGDCGCPYVYKRGNDWVVIGVHTAAARGGNTVICATQGPDGEATLEGGDNHGT
YCGAPILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRD
QLKPFTAPRGKPPRPATLEAAKETICNVLEQVIEPPQKWSYAQACASLDKTTSSGHPH
HMKKNDNWNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYENIKK
RLLWGSDLGTMIRCARAFGGLMDEMKANCVNLPIRVGMNMNEDGPIIFEKHSKYKYHY
DADYSRWDSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKITINEG
LPSGVPCTSQWNSISHWLITLCAISEVSGLSPDVVQTNSCFSFYGDDEIVSTDIKLDP
MKLTNKLKEYGLIPTRPDKTEGPLIIKESLEGLTFLRRDVCRDPAGWYGKLDQSSIMR
QLYWTKGTNHDDPNETMIPHSQRPIQLMSLLGEAALHGPTFYKKVSKLVITELKEGGM
DFYVPRQEPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide <1..1029
/gene="ORF1"
/product="p48"
mat_peptide 1030..2127
/gene="ORF1"
/product="NTPase"
mat_peptide 2128..2649
/gene="ORF1"
/product="p22"
mat_peptide 2650..3048
/gene="ORF1"
/product="VPg"
mat_peptide 3049..3591
/gene="ORF1"
/product="Pro"
mat_peptide 3592..5121
/gene="ORF1"
/product="RdRp"
gene 5105..6727
/gene="ORF2"
CDS 5105..6727
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27349.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNSETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGSDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6727..7506
/gene="ORF3"
CDS 6727..7506
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27350.1"
/translation="MAGAFIAGLAGDLLTSSVGSLVNAGANAINQKVDFENNKQLQSA
SFQHDKEMLQAQVKATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNVPQSKSAKPRSLAPSSSSSSVYSTYTQST
HLTSGSSSNASSASTRLTNLSSGSSQNRTAEWVNQQRSLSPYMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 tctaacgacg ctgccactgc gaccgctggc aaaaccagca caaacagtga aattcacaac
61 aaagatgtaa acactacatc aagcctcttc gccaacatga ccgttggctt gaagagggcc
121 ctgggggcga ggccaaaaca gcctgcctcc agggtctcct cccccagtag ggaggggaag
181 tctgaaacca ccactaggac tcccccccta aacaagggag gaagggacaa caccccccaa
241 atacctcccc cgccacccaa tggtgaggac ataatcatca aatacaccaa acaagatgat
301 gtgattgcag gggtgcccac tgtcgctacg gtggacgtcc ccccaacaca caataccgcc
361 tacagtgtcc cccccttgga tcagagggag aaggttgagg caaaggaacc tctgacaggc
421 tcaataattg agatgtggga tggtgaaatt tatcactatg ggctctatgt tgagaagggc
481 ttggttcttg gagtgcacaa acccccggct gccataagct tcgcgcgcat agagctcacc
541 cccctatcct tatactggag aacagtctac acaccacctt acctggtagc cccagaaaca
601 cttagaagac tccacggaga gtcgttccca tacaatgcat ttgacaacaa ttgctactcc
661 ttctgctgct gggtcttgga cctgaatgat tcctggctta acagaaagtt tgtttcgagg
721 accacaggtt tctacagacc ctaccaagag tggaacagaa agcccctacc aaccatggat
781 gagggaaaac tcaagaaagt ggccaatgtg ctactgtgcg gcctctccgg tcttttcact
841 agaccaatca aggacctcat agggaaacta agaccattga acattctcaa catcatcacc
901 aattgtgatt ggactttccc cggagttgtg gaagctctca tattacttgc agaactcttc
961 ggagtcttct ggacaccacc agacatttcc acttttatag cgtcacttct gggtgattat
1021 gaaatgcagg gccccgagga cattgcagtt gaagttgtgc cagtaattct cggtggcata
1081 ggcatggtac tcgggttcac caaagagaga atcggccggt tgctgagctc tgccgcttct
1141 tcgcttaggg cgtgcagaga gatcggtaat tacggaatag aggtggtgaa gttggtgatg
1201 aaatggtttt tccccaccaa agatgagaca aatgagatgg acatggtgag ggcaatagag
1261 gatgccgtgc tcgactttga ggccatacaa aacaaccaca tgacatcact actcaaagac
1321 aaaaacagcc tggcaacctt cctcagggag ttagacatgg aagaggagaa agcgcggaag
1381 ttatcaacaa agtccgcgtc cccagatatc attggaacca taaacgccct tctagccagg
1441 attgccgccg ctaggtccct agtccacaag gccaaagaag aaatgtcatc taggatgcgt
1501 cccgttgtca ttatgatctc tggccgaccc gggataggaa agacacatct agcccgcgac
1561 ctggccaaga agatggcggc gaccctctca ggtgaccaga gggtagggct cgtgccaagg
1621 aacggtgtcg atcactggga tgcatacaaa ggggagagaa ttgtgctctg ggatgactat
1681 ggaatgagca atcctgtgac cgacgcgctg cggctccaag agcttgccga cacatgcccc
1741 ctgacactca actgtgatag gatagagaat aagggaaaag tctttgacag tgacactata
1801 attatcacca ctaatttggc taatcctgcc cctttagatt atgtcaattt tgaagcttgc
1861 tctcgccgaa ttgatttcct tgtctatgcg gactccccct cggttgacaa ggcgaagaga
1921 gacttccccg gccaaccaga catgtggaaa gacgcattca aatcagactt ttcacacata
1981 aaactccaac tggcaccaca agggggcttt gataagaacg gaaacacccc ccatgggaag
2041 ggtgtcatga aatcactgac cacacactcc cttattgccc gtgccacggg tctgttgcat
2101 gagaggttag atgagttcga cctacagggg cctgaactac ctgtatacaa tttcgaccaa
2161 aatagggtgg ccgcttttag gaaacttgca gctgacaaca agtacggact cgtggaaacc
2221 ataaaagtgg gcaacaaact gaaaagtgtc agaactctag aacaactcaa ggatgcccta
2281 aaagacataa gtatcaagcc ttgcagaata atctacaatt ccatggctta tgatctcgac
2341 tcgaatgggt caggaagggt gaacgtcaaa aaggttgtgg atcataaggt ccaaactaac
2401 aatgaactca actccgcgct taacaacctg cgtggcgcta gggtaagata ctatgtcaag
2461 tgtgttcaag agatggtgta ctctctcctc cagatcgctg gcgcggcctt cgtcacttca
2521 agaatgacgc gaagattaaa cgtcagtggt atctgggcca ggccagaaaa acaggtggag
2581 gcagttgaag aacccccagc ccccccatct gaagattgga ccataacccc atcagatgca
2641 atccaagagg gtaaaaaggg caagaacaaa agtggcagag gtaagaaaca cactgccttc
2701 tccagcaaag gcctgagtga tgaggagtat gatgaattca aaagaatcag ggaagagagg
2761 cagggaaaat attccataga agaatacctc caggacagag accggtacta tgaggaattg
2821 gccatagcca aagcaacaga agaaaatttc tgtgaggagg aagaaatcaa aattagacag
2881 agggtcttcc gcccaaccag aaaacaacgc agggaggaaa gagcgaccct aggactggtc
2941 acgggtagtg aaatcaggaa aaggaacccc gatgacttca aaccaaaagg aaaattgtgg
3001 gctgatgatg accgcagtgt gaattacaat gagaaaatag attttgaggc ccctcctagc
3061 ctttggtccc gaatagtgaa ttttgggtca ggctggggtt tctgggtgtc ttctaacctg
3121 ttgatcacat caacacatgt catccccccg aacatgactg aggcttttgg tgtaccaata
3181 agccagatac aaatacacag aagtggagag ttctgcaaaa tgaggttccc caaggctata
3241 agacctgatg tctcgggcat gatcctggag gaaggagcac ctgaaggaac ggtggtgacc
3301 atactgatta agagaaccac cggtgagctc atgccattgg ctgcccgaat gggcacccac
3361 gccaccatga agatacaagg gaaaatgctt ggaggtcaaa tgggaatgct cctcacgggg
3421 tccaacgcca agaacatgga cctcggcacc attcctggag actgtggttg cccctatgtg
3481 tacaagaggg gtaatgattg ggtggtcata ggagtgcaca ccgcagctgc cagaggtggc
3541 aacaccgtga tctgcgccac ccaggggcca gatggtgagg ccacacttga gggaggagac
3601 aaccacggga cctactgtgg tgcaccaata cttggaccgg gaaatgcacc aaagctcagc
3661 accaaaacca agttctggag gtcatccaac gccccactcc cacctggcac ttatgagcct
3721 gcttacctag gaggaaagga cccaagggtc aaagggggtc cgtcattaca acaggttatg
3781 agggatcagc tcaaaccttt cactgccccc cgagggaaac caccgcggcc agcgacctta
3841 gaggctgcca aagagaccat ctgcaatgtg cttgagcaag tcattgaacc gccccaaaaa
3901 tggtcttacg ctcaggcctg tgcctcattg gataagacaa catctagtgg ccaccctcac
3961 cacatgaaaa agaatgacaa ttggaacgga gagtctttca ctggtgtatt ggctgatcag
4021 gcctctaagg ccaatcttat gtttgaacag ggaaaacaca tgcaacccgt gtacactgct
4081 gccctcaaag acgagctcgt caagactagt aagatctatg aaaacattaa gaaaagactt
4141 ctatggggct cagatctggg cacaatgatc cgttgtgcta gggcattcgg tggcctcatg
4201 gatgagatga aggcaaattg tgttaattta ccaatcagag ttggcatgaa catgaatgaa
4261 gatggaccca tcatatttga gaagcattca aaatacaaat accactatga tgctgactat
4321 tccaggtggg actcaaccca acagaggcac attcttggag ctgcccttga aataatggtt
4381 agattttcag ctgaacctga attggcacaa atagtgtctg aagacctcct agcccccagt
4441 gtggtggacg ttggcgactt caaaatcacc ataaatgaag gattgccctc tggagtgcca
4501 tgtacatcac agtggaactc aatttcccac tggctcataa cactgtgtgc catatcagaa
4561 gtttcagggc tgtcgccaga cgtagtgcaa acaaactcct gcttctcctt ctacggggat
4621 gatgagatag tcagcaccga catcaagtta gatcccatga agctgaccaa caagttgaaa
4681 gaatatgggt tgattccaac aaggccagac aagacagagg ggccgctcat aattaaagag
4741 agtcttgagg gcctaacttt cctaaggagg gacgtgtgtc gagacccagc tggttggtat
4801 ggaaaacttg accaatcttc aatcatgaga caactgtact ggactaaggg aaccaaccat
4861 gatgatccca atgagacaat gattccacac tctcagagac ccatacaatt aatgtcactg
4921 ctaggggagg cagcactgca tggtccaact ttttacaaga aagtcagcaa attggtcatc
4981 actgagctca aagagggtgg gatggatttc tatgtaccaa gacaagaacc tatgttcaga
5041 tggatgagat tctcagacct cagtacttgg gagggcgatc gcaatcttgc tcccgaaggt
5101 gtgaatgaag atggcgtcga atgacgccgc tccatctaat gatggtgctg ctggtctcgt
5161 accagagggc aacagcgaga ccctccccct agaaccagtt gcgggcgcag ctatagccgc
5221 acccgtcact ggtcaaaaca acataattga cccctggatt agaacaaatt ttgtgcaagc
5281 accaaatgga gagttcacag tgtcacccag aaactctcct ggagaaattt tattaaactt
5341 agagttgggc cctgatttga acccttattt ggctcatttg tcaaggatgt acaatgggta
5401 cgctggtgga gtggaagttc aggttctcct ggcagggaac gcgttcactg ccggaaagat
5461 cctcttcgcc gccgtcccgc caaattttcc agtagaattt ttaagcccag cccagatcac
5521 aatgctccct catttaatag tagatgttag gactcttgaa ccaattatga tcccacttcc
5581 tgatgttagg aatacattct tccattataa taaccagcct aacagccgca tgagattagt
5641 ggctatgctc tataccccac tcagatctaa tggctcaggt gatgacgtct ttactgtctc
5701 ttgcagggtt ttgactaggc ccactcctga ttttgagttc acttatttag tgccaccttc
5761 tgttgaatct aaaaccaagc ctttttcttt gcctatttta accctttctg agctcacaaa
5821 ttcgaggttc ccagtcccca tcgattcgct tttcaccgcc cagaataatg tattgcaggt
5881 acaatgtcaa aatggcaggt gtacacttga tggtgagcta caaggcacaa cccagttgct
5941 cccatctggc atctgtgcat tcagaggacg ggtgacagca caaattaacc aacgtgacag
6001 gtggcacatg caactgcaaa acctcaatgg cacaacatat gacccaactg atgatgtgcc
6061 agccccgctg ggtacacctg acttcaaggg cgtcgtgttt gggatggtaa gccaaagaaa
6121 tgtgggtagt gatgcgcctg gctcaaccag agcccagcag gcgtgggttt caacctatag
6181 cccccaattt gtccccaaat taggttctgt caatcttaga attagtgata atgatgactt
6241 ccaattccag ccgacaaaat tcacaccagt gggcgtcaat gatgacgatg atggccaccc
6301 gttcagacaa tgggaattac caaactattc aggggagctt accttgaata tgaatcttgc
6361 ccccccagtt gctccaaatt ttcctggtga acaattgtta ttcttcagat cttttgtgcc
6421 atgctcagga ggctacaacc aaggtatcat agattgtctt attccccaag aatggatcca
6481 acacttctat caggaatcag caccctccca gtcagatgtg gccctaatca ggtatgtcaa
6541 ccctgatacg ggacgtacac tgtttgaagc aaaattgcac agatctggtt acattactgt
6601 ggctcactct ggagactatc ctcttgttgt accggctaat ggacatttta gatttgattc
6661 ttgggtaaat cagttttact cactcgcccc aatgggaact gggaatgggc gaaggagggc
6721 tcagtaatgg ctggggcttt cattgcagga ttggcaggcg acttgctcac gtcatctgtg
6781 ggctcccttg tgaacgcagg ggcaaacgcc atcaaccaga aggtagactt tgaaaacaac
6841 aaacaactcc agtctgcttc cttccagcat gacaaagaga tgctccaagc gcaggtgaag
6901 gcaaccaaac agctgcaatc tgaaatgata gccttaaaac agggggtttt ggccgcaggc
6961 ggcttttccc ccactgatgc agcaagggga gccattggtg cacccatgac aaaggtgctt
7021 gactggtctg gcactcgata ctgggcgccc aactccacaa agacaactgg ttattcggga
7081 caattcacct cttcacctgt gcacatgtct agcccaaatg ttccacaatc aaaatctgca
7141 aagcctagat ctctagctcc ttcctcttct tctagcagtg tctatagcac gtatactcaa
7201 tctacacatt taacatctgg ctcttctagt aatgcttctt ctgcctccac aagattgaca
7261 aatttaagct ctggctcctc tcaaaataga acagcagagt gggtaaatca acagagaagt
7321 ctcagcccct acatgagtgg cgcacttaac atttcacatg tcacgccacc ctcaagtagg
7381 gcttccagtt ctgggacggt ctcgaccgtg cccaaggaag ttttggactc ctggacgtct
7441 gcgtttaaca cacacagaca gccgctcttc gcacacctca gagtgagggg ggagtcacgt
7501 gtttagtgaa aagaaataat tggccataat gtgatttctt tctgaatttg gctaatttgt
7561 gtcttttaaa aaaa
//