Typing tool
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Typing tool
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Complete norovirus genomes
| PV920382 | GII.17 | |
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|---|---|---|---|
| GII.P17 |
ORF1: 1..5100
ORF2: 5081..6703
ORF3: 6703..7482
LOCUS PV920382 7539 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2055-1/2021/UK
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PV920382
VERSION PV920382.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7539)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7539)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7539
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2055-1/2021/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jul-2021"
/note="genotype: GII.17[P17]"
gene <1..5100
/gene="ORF1"
CDS <1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27345.1"
/translation="ASNDASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQ
PPPGETKQIQKPPRPPTPELVKRIPPPPPNDEDEPGIVYKVGEGVSGLPDLTTVVQPD
AQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAIS
FAKIEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGK
LRPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTALLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAREL
AKKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEK
AKRDFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARA
SGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTL
DELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELAGALHHLR
SARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGC
PKPRDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSP
SLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEG
TVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACVSLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDEFKVNCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGP
NHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQE
SMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6703
/gene="ORF2"
CDS 5081..6703
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27346.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISNNDDFQFQPTKFTPVGVN
DDDDDHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6703..7482
/gene="ORF3"
CDS 6703..7482
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27347.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSSPVHMSSPNAPQLKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 gcgtctaacg acgcttccgc tgccgttgct ggcaaaaaca acaacaacga caaggaaaaa
61 tcttcaagtg acagcttgtt tgctaacatg tctgtcactt ttaagaaagc cctcggggcg
121 cggtctaagc aaccgccccc gggagaaaca aaacaaatac aaaaaccacc aaggccaccg
181 acaccggaat tggttaagag aatacctcca cccccaccca atgacgagga tgaaccaggg
241 atagtgtaca aggtgggaga gggtgtgtct gggctgcccg acctaacaac tgtggtacaa
301 cctgacgcac aaaacacagc ttatagtgtt cccccactta gccagagaga agtcggcgaa
361 gctaaagaac cgctgcctgg ctccattctg gaaatgtggg atggtgagat ctaccactat
421 gggctgtatg ttgagcgggg gcatgtgctc ggagtacaca aaccacctgc tgcaataagc
481 tttgccaaaa ttgaaataac accgctgtct ctctactgga gagtggtcta cactccccag
541 tatttgatag atccaggaac tcttaagaac ttgagtggag agactttccc gtacacggcc
601 tttgacaaca actgttatgc cttctgttgt tgggtcctag acctcaacga ctcctggctt
661 agcaggagaa tgatccaaag aacaactgga ttcttcaaac cttatcagga ttggaacaga
721 aaacccttac caaccatgga tgaaccgaaa atcaagaagg ccgcgaatgc tgtcctatgc
781 gctctctcct cactcttcac tagacccatt aaagacatca ttggaaagct tagaccactg
841 aacattctta atatactggc aacctgcgat tggacttttg caggcatagt ggaatccttg
901 atccttcttg ctgaactctt tggggtgttc tggacacccc cagatgtgtc tgcgatgatt
961 gctcccttac tcggtgacta cgagatgcaa ggccccgaag acctggccgt ggaacttgtg
1021 cccgtggtga tgggaggaat aggtttggtg ttaggattca ccaaagaaaa gatcggcaag
1081 atgctttcat cagctgcgac cacacttagg gcctgcaagg atctaggatc ttatggattg
1141 gaaatactca aattggtcat gaagtggttc ttccccaaga aggaggaggc taacgaacta
1201 gccatggtga gggccattga ggatgcagtc ctggatttgg aggcaataga aaacaatcac
1261 atgaccgccc ttctcaagga taaagacagc ctggccacat acatgaggac tctggacttg
1321 gaagaagaga aagcaaggaa actgtcaacc aaatcggcgt cgcctgacat cgtgggtaca
1381 ataaacgcat tgttggctag gatagcagcc gccaggtcac tggtccacaa ggctaaggag
1441 gagctctcga gcaggcagag acctgttgtt gtaatgatat caggtagacc aggtatagga
1501 aagacccatc tggccagaga gctagccaag aaagttgcgt caacactgtc aggcgaccaa
1561 aggattggac tggtacctag gaatggcgtc gaccattggg acgcctacaa gggagaaagg
1621 gtggtcctgt gggatgatta tggtatgagc aaccccatac aggacgcact gaggctccaa
1681 gaattggctg acacctgtcc tctgacccta aattgtgata ggattgaaaa caaaggaaaa
1741 gtgttcgaca gtgatgccat aattataaca accaaccttg caaatccagc accactagac
1801 tatgtcaact ttgaggcctg ctctagacgc atagacttct tggtgtatgc agacgcacct
1861 gacattgaga aggctaagcg tgacttccct ggccaaccag atatgtggaa agaccatttc
1921 agaccagact tctcacacat taaacttcag ctggcaccac agggaggttt tgacaaaaat
1981 ggcaacaccc cacatggcaa aggtgtggta aagtccctga cgattggttc tctgatcgcc
2041 agggcctccg gcttgctcca cgagagaatg gatgaattcg agctccaagg ctctgacctg
2101 ccaaccttca attttgaccg caacaaagtc gccgccttca gacaattagc agctgaaaac
2161 aaatatggtc ttatggacac attgagggtc ggcaaccaac tgaaaagtgt taagaccctg
2221 gatgagctga agcaggccat aaagaacatc agtatcaaga agtgtcagat agtgtataat
2281 ggatgcacct ataccatgga atctgatggg aggggcaagg ttgtggttga aaaggtacaa
2341 aacgcaacag ttcaaaccaa caatgagctt gcaggggcgc tccaccacct gagatctgca
2401 aggataagat actatgttaa atgtttccaa gaggccattt actctctact ccaaattgct
2461 ggtgcagcct ttgtcacctc acgcatcgtg aggcgcatga acatatcaaa cctctggtcg
2521 aagccaccca tcgaggaggg tgatgaacct gaagacagag gaggatgccc caagcccagg
2581 gatgaagatg acctcactat tgactctaga gacattaaag tggaagggaa gaagggcaag
2641 aacaagtctg gccggggcaa gaaacacaca gccttttctt ccaagggcct cagtgatgaa
2701 gagtacgatg agtacaagag aatcagagag gagaggaatg gcaaatactc aatagaggaa
2761 tacctccaag atagggacag atactatgaa gagcttgcca ttgctaaggc cactgaggag
2821 gacttctgtg aggaggagga gatcaaaatc cgccagagaa tcttccgacc caccaggaag
2881 cagcggaaag aggaaagggc cacgcttggg cttgtcacag gatcggaaat cagaaagagg
2941 aatccagatg actttaaacc aaaaggaaaa ttgtgggctg atgacaacag gagcgtggat
3001 tacaatgaga ggatagattt tgaggctccc ccgagtgttt ggtctaggat agtcaacttt
3061 ggcacaggct ggggattctg ggtttctcca agtctcttta taacttcaac acacgtcata
3121 ccaaaaggaa tcactgaggc ctttggagtg cccataaacc aaatccaaat tcacaaatct
3181 ggagaatttt gccgcttgcg gtttccaaag ccaattagac cagacgtgag tgggatgatc
3241 ttggaagagg gcgcccctga aggcactgtt gtgtctattc tcatcaaaag gacaacaggg
3301 gagctgatgc ctcttgcagt cagaatgggg actcatgcca caatgaaaat ccaaggtaga
3361 acggtgggtg gtcagatggg tatgcttctc actggctcaa atgctaaagg catggatcta
3421 ggcacaacgc caggtgactg cggatgtcca tacatataca aaaggggcaa tgaccttgtg
3481 gtcattgggg tgcacactgc agcagctcgt ggaggcaaca cggtcatatg tgccacacag
3541 ggaagtgaag gtgaagccac tcttgaagga ggtgacaaca agggtaccta ttgtggagcc
3601 cccattttgg gacctggcaa tgcaccaaaa ttgagcacaa agacaaaatt ctggagatcc
3661 tctaacgcac cgcttccccc aggtacttat gaaccagcat accttggtgg gagagacccc
3721 cgcgtgaagg gaggcccatc tctgcaacaa gttatgaggg accaacttaa accttttaca
3781 gagcccagag ggaagccacc aaacccaaat gtcttagagt cagcaaagaa gactatcatc
3841 aatgttctgg aacaaaccat tgacccccct caaaagtggt catatgccca agcttgtgta
3901 tccctcgaca agacaacctc cagtggatac ccgcaccacg tccggaagaa tgactattgg
3961 agtggtgaat ccttcacagg aaaacttgca gatcaggctt caaaagcaaa tctcatgtat
4021 gaggaaggca agcacatgca accagtttac accgcagcac tcaaagacga gctcgtgaaa
4081 actgacaaaa tttatggcaa aataaagaaa agactcctgt ggggttctga cctctccaca
4141 atgattcgat gcgccagagc atttggtggt ctcatggatg aattcaaagt aaattgtatt
4201 acactcccta tcagagttgg tatgaatatg aatgaagatg gtcccataat atttgagaaa
4261 cactccaggt acaggtacca ctatgatgct gattactccc gctgggactc cacacaacag
4321 cgggcagtgc tggaagcggc acttgaaatc atggtaagat tttctgctga gccacagctg
4381 gcacaaatag tggcagagga cctgctgtca ccaagtgtgg ttgacgtggg cgatttcaaa
4441 atcgccatca atgaaggcct accatctggc gtgccttgca cctcacaatg gaattctatt
4501 gcccactggt tacttacctt gtgtgccctt tctgaagtga caggattagg tcctgacatc
4561 atacaagcta actccatgta ctctttctat ggtgatgatg agattgtgag cacagacata
4621 aaattggacc cagagaaatt gaccgcaaag ctcaaagaat atggccttaa acccactcgg
4681 cccgacaaaa ctgaggggcc gttggtgatt agtgaggacc tgaatgggtt gactttcctc
4741 cgccgaacag tcacccgtga tccagcaggt tggtttggaa agttggacca aaactccatc
4801 ctcaggcagt tgtactggac aagaggaccc aaccatgaag accccagtga gaccatgata
4861 ccacacgcac aaagacctgt gcagctcatg gcactactag gagaatcctc cctacatgga
4921 ccctcatttt acagcaaggt tagcaaacta gtcatatctg aacttaaaga gggaggaatg
4981 gatttttatg tgcccagaca agagtcaatg ttcagatgga tgaggttctc agatctaagc
5041 acatgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tctaatgatg gtgctgctgg tctcgtacca gagggcaaca acgagaccct
5161 tcccctagaa ccagttgcgg gcgcagctat agccgcaccc gtcactggcc aaaataatat
5221 aattgacccc tggattagaa caaattttgt gcaagcacca aatggagagt tcacagtgtc
5281 acccagaaac tctcctggag aaattttatt aaatttagag ttgggccctg atttaaaccc
5341 ttatttggct catttgtcaa ggatgtacaa tgggtatgct ggtggagtgg aagttcaggt
5401 tctcctggca gggaacgcgt tcactgccgg aaagatcctc ttcgccgccg tcccgccaaa
5461 tttcccagtg gaattcttaa gcccagccca gatcacaatg ctcccacatt taatagtaga
5521 tgttaggact cttgaaccaa ttatgatccc actccctgat gttaggaata cattcttcca
5581 ttacagtaac cagcctaaca gccgcatgag attagtggct atgctctaca ccccactcag
5641 atctaatggc tcaggtgatg atgtttttac tgtctcttgc agggttttga ctaggcctac
5701 tcctgatttt gagttcactt atttagtgcc accttctgtt gaatctaaaa ctaagccttt
5761 ttccttacct attttaaccc tttctgagct cacaaattcg aggtttccag tccccatcga
5821 ttcgcttttc accgcccaga ataatgtgtt gcaggtgcag tgtcaaaatg gcagatgtac
5881 acttgatggt gagttacaag gcacaaccca gttgctccca actggcatct gtgcattcag
5941 aggacgggtg acagcacaaa tcaaccaacg tgacaggtgg cacatgcaac tgcaaaacct
6001 caatggtaca acatatgacc caactgatga tgtgccagcc ccgctgggta cacctgactt
6061 caagggcgtc gtgtttggga tggtaagcca aagaaatgtg ggtaatgatg cgcctggctc
6121 aaccagagcc caacaggcgt gggtttcaac ctatagcccc caatttgtcc ctaaattagg
6181 ttctgttaat cttagaatta gtaataatga tgatttccaa ttccagccga caaaattcac
6241 accagtgggc gtcaatgatg acgatgatga ccacccattc agacagtggg aactaccaaa
6301 ctattcaggg gagcttacct tgaatatgaa tcttgccccc ccagttgctc caaattttcc
6361 tggtgaacaa ttgttattct tcagatcttt cgtgccatgc tcgggaggtt acaaccaagg
6421 tattatagat tgtcttattc cccaagaatg gatccaacat ttctatcagg aatcagcacc
6481 ctcccagtca gacgtggccc taatcaggta tgttaacccc gacacgggac gtacactgtt
6541 tgaggcaaaa ttgcacagat ctggttatat tactgtggct cactctggag actatcctct
6601 tgttgttccg gctaatggac actttagatt tgattcttgg gtaaatcagt tttactcact
6661 cgccccaatg ggaactggga atgggcgaag gagggctcag taatggctgg ggctttcatt
6721 gcaggattgg caggcgacat gctcacgtca tctgtgggct cccttgtgaa cgcaggggca
6781 aacgccatta accaaaagat agactttgaa aacaataaac aactccagtc tgcttccttt
6841 cagcatgata aagagatgct ccaagcgcag gtgagggcaa ccaagcagct gcaatctgaa
6901 atgatagccc taaaacaggg ggttttggcc gcaggcggct tttcccccac tgatgcagca
6961 aggggatcca ttggtgcacc catgacaaag gtgcttgact ggtctggcac tcgatactgg
7021 gcgcccaatt ccacaaagac aactagctat tcgggacaat ttacttcttc acctgtgcat
7081 atgtctagcc caaatgctcc acaattaaaa cctgcaaagc ctaggtctct agctccttcc
7141 tcttcttcta gcagtgtcta tagtatgtat actcaatcta ctcatttgac atctggttct
7201 tctagcaatg cttcttctgc ctccacaaaa ttgacaaatt taagctctgg ctcctctcaa
7261 aacagaacag cagagtgggt aaatcaacag agaagtctta gccctttcat gagtggcgca
7321 cttaacatct cacatgtcac gccaccctca agtagggctt ccagttctgg gacggtctcg
7381 accgtgccca aggaagtttt ggactcctgg acgtctgcgt ttaacacaca cagacagccg
7441 ctcttcgcac acctcagagt gaggggggag tcacgtgttt agtgaaaaga aataattggc
7501 tataatgtga tttctttcta aatttggcta atttgtatc
//