Typing tool
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Typing tool
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Complete norovirus genomes
| PV920381 | GII.17 | |
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|---|---|---|---|
| GII.P17 |
ORF1: 1..5103
ORF2: 5084..6700
ORF3: 6700..7479
LOCUS PV920381 7548 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2398/2022/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920381
VERSION PV920381.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7548)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7548)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7548
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2398/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jun-2022"
/note="genotype: GII.17[P17]"
gene <1..5103
/gene="ORF1"
CDS <1..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27342.1"
/translation="MASNDASVAVAGKNNNNDKEKSSSDNLFSNMTVTFKKALGARSK
QPPPGETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQP
DAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIG
KLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLS
SKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGSGLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHL
RSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGG
CPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGL
VTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPRLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6700
/gene="ORF2"
CDS 5084..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27343.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDNDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6700..7479
/gene="ORF3"
CDS 6700..7479
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27344.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 atggcgtcta acgacgcttc cgtcgccgtt gctggcaaaa acaacaacaa cgacaaggaa
61 aaatcttcaa gtgacaactt gttttctaac atgactgtta cttttaagaa agccctcggg
121 gcgcggtcta aacagccgcc cccgggagaa acaaaacaaa cacaaagacc accaaggcca
181 ccgacaccgg aattggtgaa gaagataccc ccaccccccc ccaatggcga ggatgaacca
241 aagatagcgt ataaggtggg agaaggtgtg tctgggctgc ccgacttgac aaccgtggca
301 caacctgacg cacagaacac agcctacagt gtccccccac ttagccagag agaggtcggc
361 gaagctaaag aaccgttgcc tggctccatt ctggaaatgt gggatggtga gatctaccac
421 tatgggctgt atgttgagcg ggggcatgta ctgggagtgc acaaaccacc tgccgcaata
481 agccttgcca aaattgaatt aacaccgctg tctctctact ggagagtggt ttacactcct
541 caatatttga tagctccaga gacccttaag aatttaaatg gagaggcttt cccatacacg
601 gcctttgaca acaactgtta tgccttctgt tgttgggttt tagacctcaa cgactcctgg
661 cttagcagaa gaatgatcca aagaacaact ggattcttca gaccgtatca ggactggaac
721 agaaaaccct tgccaaccat ggatgaacca aaaatcaaga aggccgcgaa tgctgttctg
781 tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa gctcaaacca
841 ctgaacatta tgaacatact ggcaacttgt gattggactt ttgcgggcat agtggaatcc
901 atgatccttc ttgctgagct ctttggggtg ttctggacgc ccccagatgt gtctgcaatg
961 attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc cgtggaactt
1021 gtgcccgtgg taatgggggg aataggtttg gtgttaggat tcaccaagga aaagatcggc
1081 aagatgcttt catcagctgc gaccacactc agggcctgca aggatctagg gtcttatggg
1141 ttggagatac tcaaactggt catgaagtgg ttcttcccca agaaggagga ggccaacgag
1201 ttagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat agaaaacaat
1261 cacatgacca ctctccttaa ggacaaagac agtctggcca catacatgag gactcttgac
1321 ttggaagaag aaaaagcaag gaaactgtca tccaaatcgg cgtcacctga catcgtgggc
1381 acagtaaacg cattattggc aaggatagca gccgccaggt cactggtcca caaggctaag
1441 gaggagctct cgagcagaca gaggcctgtt gttgtaatga tatcaggtag gccaggtata
1501 ggaaagaccc atctggccag agagctagcc aagaaggttg cgtcaacact gtcaggcgac
1561 caaaggattg gactgatacc tagaaatggc gtcgaccatt gggacgccta caaaggagag
1621 cgagtggttc tgtgggatga ctatggcatg agcaacccta tacaggacgc actgaggctc
1681 caagaattgg ctgacacctg tcctctgacc ctaaattgtg acaggattga aaacaaagga
1741 aaagtgttcg acagtgacgc cataattata acaaccaacc tcgcaaaccc agcaccactg
1801 gattatgtca actttgaggc ttgttctaga cgcatagact tcttggtgta tgcagacgca
1861 cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg gaaagaccat
1921 tacagatcag acttctcaca cattaaactt cagctggcac cacagggagg ctttgataag
1981 aatggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg ttctctgatc
2041 gccagggctt ctggcttgct ccatgagaga atggatgaat ttgagctcca aggctctggc
2101 ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt ggcagctgaa
2161 aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag tgtcaaaacc
2221 ctggatgagc tgaagcaggc tataaagaac atcaccatca agaagtgcca gatagtgtac
2281 aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt tgaaaaggtt
2341 caaaatgcaa cagtccaaac caacaatgaa cttgcaggag cactccacca cctgagatct
2401 gcaaggataa ggtattatgt taaatgtttc caagaagcta tttactctct actccaaatt
2461 gctggtgcag ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc aaacctctgg
2521 tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg ccccaagccc
2581 agggatgaag atgacctcac tattgactct aaagacatta aagcagaagg gaagaagggc
2641 aagaacaaat ctggccgggg caagaaacac acagctttct catccaaggg cctcagtgat
2701 gaagagtacg atgagtacaa gagaatcagg gaggagagga atggcaaata ctcaattgaa
2761 gaatacctcc aggataggga tagatactat gaagagcttg ccattgctaa ggccactgag
2821 gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg gcccaccagg
2881 aagcaacgga gagaggaaag agccacgctt gggcttgtca caggatcgga aatcagaaag
2941 aggaacccag atgactttaa gccaaaagga aaattgtggg ctgatgacaa cagaagtgtg
3001 gactacaatg agaggataga ttttgaggct cccccgagtg tttggtctag gatagtcaac
3061 tttggtacag gatggggatt ctgggtctcc ccaagtctct ttataacttc aacacatgtc
3121 ataccaaaag gaatcactga ggcctttgga gttcccatta accaaattca aattcacaaa
3181 tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt gagtggaatg
3241 atcttggaag agggtgcccc tgaaggcact gttgtgtcca ttctcatcaa gaggacaaca
3301 ggggaactga tgcctctcgc agttagaatg ggaactcatg ccacaatgaa aatccaaggt
3361 agaacggtgg gtggtcaaat gggcatgctt ctcactggct caaacgctaa aagcatggac
3421 ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg caatgacttc
3481 gtggtcattg gggtgcacac tgcagcagcc cgtggaggca acacggtcat atgtgccaca
3541 cagggaagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac ctattgtgga
3601 gcccccatct tgggacctgg caacgcacca agattgagca caaaaacaaa attttggaga
3661 tcttctaacg cgccgcttcc tccaggtacc tatgaaccag cataccttgg tggaaaagac
3721 ccgcgtgtga agggaggccc atctctacaa caagttatga gagaccaact taaacctttt
3781 acagagccca gggggaagcc accaaaacca agtgtcctgg aatcagcaaa gaagaccatc
3841 attaatgttc tggagcaaac cattgacccc cctgaaaagt ggtcatatgc ccaagcttgt
3901 gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa gaatgactat
3961 tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc aaaccttatg
4021 tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga cgagctcgtg
4081 aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc tgacctatcc
4141 accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa agcaaattgt
4201 atcacactcc ctgtcagagt tggtatgaac atgaatgaag atggtcccat aatatttgaa
4261 aagcactcca ggtacaggta ccactatgat gctgattact cccgctggga ttccacacaa
4321 cagcgggcag tgctggaagc ggcacttgaa atcatggtga gattttctgc tgagccacag
4381 ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt gggcgatttc
4441 aaaattgtta tcaatgaagg cctaccatct ggcgtgcctt gcacttcaca atggaactcc
4501 attgcccact ggttactcac cctgtgtgcc ctgtctgaag taacaggact aggccctgac
4561 atcatacaag ccaactccat gtactctttc tatggtgatg atgagatcgt gagcacagac
4621 ataaaattag acccagagaa attgactgca aaactcaaag aatatggtct taaacccacc
4681 cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg gttgactttc
4741 ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga ccaaaactcc
4801 atcctcaggc agctgtactg gacaagggga cccaaccatg aagaccccag tgagactatg
4861 ataccacacg cacagagacc tgtgcagctc atggcactgc taggagagtc ctccttacat
4921 ggaccctcat tttacagcaa ggttagcaag ctggtcatat ctgaacttaa agagggagga
4981 atggattttt atgtgcccag acaagagtca atgttcaggt ggatgaggtt ctcagatcta
5041 agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca ataacgagac
5161 ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg gccaaaacaa
5221 tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag agttcacagt
5281 gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc ctgatttgaa
5341 cccttatttg gctcatttgt caaggatgta caatgggtac gctggtggag ttgaagtcca
5401 ggttctcctg gcagggaacg cgttcactgc cggaaagatc ctcttcgccg ctgtcccgcc
5461 aaatttccca gtggaattct taagcccagc ccagattaca atgctcccac atataatagt
5521 agatgttagg actcttgaac caattatgat cccattacct gatgttagga acacattctt
5581 ccactataat aaccagccca acagccgcat gagattagtg gctatgctct atacccccct
5641 tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt tgactaggcc
5701 tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta agactaagcc
5761 cttttcctta cccattttaa ccctttctga gctcacaaat tcgaggttcc cggtccccat
5821 tgattcgctt ttcaccgccc agaataatgt gttgcaggtg cagtgtcaaa atggcaggtg
5881 cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca tctgtgcgtt
5941 cagaggacgg gtgacagcag aaactgacaa tcctgataag tggcacatgc aactgcaaaa
6001 cctcaatggc acaacgtatg acccaactga tgatgtgcca gccccactgg gtacacctga
6061 cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg atgcgcccgg
6121 ctcaaccagg gctcatgagg cggtgatttc aacctacagc cccagatttg ttcccaaatt
6181 aggctctgtc aattttaaaa gtaatgacaa tgatttccaa ttgcagccaa caagattcac
6241 accagtgggc attaatgatg atggtgacca cccgttcaga caatgggaac tgccagacta
6301 ttcaggggtg cttaccttga atatgaacct tgcccccccg gttgctccaa atttccctgg
6361 tgaacaatta ttactcttca gatcttccgt gccatgttca ggaggttaca accaaggtat
6421 tatagattgt cttatccccc aagaatggat ccaacacttc taccaggaat cagcaccttc
6481 tcagtcagac gtggccctga tcaggtacgt caaccccgac acgggtcgca cactgtttga
6541 ggcaaaattg cacagatctg gctatatcac tgtggctcac tctggagact atcctcttgt
6601 tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt actcactcgc
6661 cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc tttcattgca
6721 ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc aggggcaaac
6781 gccatcagcc aaaagataga ctttgaaaac aacaaacaac tccagtctgc ttcctttcaa
6841 catgataaag agatgctcca agcgcaggta aatgcaacca agcagctgca atctgagatg
6901 atagccctaa aacagggggt tttggccgca ggcggctttt cccccactga tgcagcgagg
6961 ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg atattgggct
7021 cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc tgtgcacatg
7081 cccagcccga gtgctccaca atcaaaaccc gcaaagccca gatctctagg ttcttcttct
7141 tcttctagta gtgtttatag tatgtctacc caatcaactt ctctaacatc tggctcttct
7201 agtaatgctt cttctgcttc tacaaaattg acaaatttaa gctctggctc ctctcaaaac
7261 aggacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag tggcgcactc
7321 aatatctcac atgtcacgcc accttcaagt agggcctcca gttctgggac ggtctcaacc
7381 gtgcccaagg aagttttgga ctcctggaca tctgcattta acacacgcag acagccgctc
7441 ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat aattggctat
7501 aatatgattt ctttttaaaa tttggctaat ttgtatttct tttaaaaa
//