Typing tool
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Typing tool
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Complete norovirus genomes
| PV920379 | GII.17 | |
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| GII.P31 |
ORF1: 1..5092
ORF2: 5073..6695
ORF3: 6695..7474
LOCUS PV920379 7531 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2406/2018/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920379
VERSION PV920379.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7531)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7531)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7531
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2406/2018/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Sep-2018"
/note="genotype: GII.17[P31]"
gene <1..5092
/gene="ORF1"
CDS <1..5092
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XXN27336.1"
/translation="ASNDASAAAAANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQP
PPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPDEVN
TAFSVPPLNQRENRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLAK
VELTPLSLFWRPVYIPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKP
LNILNILATCDWTFAGVVESMILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EENELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVVMISGKPGIGKTHLARELAKK
IAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVERAKR
DFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMPDL
KQALKNVAIRKCQIVYGGSTYTLEADGKGSVKIDKVQSAAVQTNNEIAGALHHLRCAR
IRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSRPQVEDTEETASKDGCPKP
KEDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGS
EIRKRNPDDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVSIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVA
TLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGS
APKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVRGGPSLQQVMRDQLKPFTEPRGK
PPRPNVLEAAKKTIINVLEQTIDPPQKWSFSQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGRLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQ
QRDVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHE
DPSETMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..982
/gene="ORF1"
/product="p48"
mat_peptide 983..2080
/gene="ORF1"
/product="NTPase"
mat_peptide 2081..2617
/gene="ORF1"
/product="p22"
mat_peptide 2618..3016
/gene="ORF1"
/product="VPg"
mat_peptide 3017..3559
/gene="ORF1"
/product="Pro"
mat_peptide 3560..5089
/gene="ORF1"
/product="RdRp"
gene 5073..6695
/gene="ORF2"
CDS 5073..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27337.1"
/translation="MKMASNDAAPSNDGATGLVPEINNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNQPANRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPVPVDSLFTAQNNNLNVQCQNGRCTLDGELQGTT
QLQPSGICAFRGKITADVRPNHDDRWHMQLTNFNGTPFDPTEDVPAPLGTPDFTGLLF
GVASQRNVQPNPNTTRAHEAVISTTSSQFVPKLGSINFGSTSEDFIVGQPTKFTPVGI
KIEDGHAFDQWTLPRYSGHLTLNMNLAPPVAPNFPGEQLLFFRSNVPCAGGISDGVID
CLLPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRTGYITVAHSGDYPLV
VPSNGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6695..7474
/gene="ORF3"
CDS 6695..7474
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27338.1"
/translation="MAGAFIAGLAGDMLTNTVGSLANAGANAITQKIDFENNKQLQSA
SFQHDKDMLQAQVAATKQLQADMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTRTTGYSGQFTSAPVHIPTKMIQPTPVKRTQPLSSSSGSAYSLSTQSTAL
TKPSSGSSSVSSASTQSTKLSSVSSMDRTANWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTPAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ggcgtctaac gacgcttccg ctgccgctgc tgccaacagc aacaacgaca ccgcaaaatc
61 ttcaagtgac ggtgtgctct ctagcatggc tgtcactttt aaacgggccc tcggggcgcg
121 gcctaaacag ccgcccccga aggaaatacc acccagaccc ccacggccac ccacaccaga
181 gttggtcaaa aagatccctc ctcccccacc caacggggag gatgaactag tggtttccta
241 tagcgccaaa gatggtgttt ccgggctgcc tgagctcacc actgtcagac aaccggatga
301 agttaacacg gcgttcagtg ttcccccgct caaccaaagg gagaacaggg acgccaagga
361 accattaact ggaacaatta ttgagatgtg ggacggagaa atctaccatt acggcctgta
421 cgtggaacga ggtcttatac ttggtgtgca taagccaccg gcggccatca gccttgccaa
481 agtcgagcta acaccactct ctctgttctg gagacctgta tacatacccc agtacctcat
541 ctctccagac actctcagga gactacatgg ggagtcattc ccctacactg catttgacaa
601 caattgctac gccttctgtt gttgggtatt agacctaaac gactcatggc taagcaggag
661 aatgattcag agaacaacag gtttcttcag accataccag gattggaaca ggaaacccct
721 ccccactatg gatgattcca aattgaagaa ggtggccaac atattcttgt gcactttgtc
781 ttcactattc accaggccca ttaaggacat aataggaaag ctgaaacctc ttaacatcct
841 taatattctg gctacatgtg attggacctt cgcaggcgta gtggaatcca tgatactctt
901 ggcagagctc tttggagttt tctggacacc cccagatgtg tctgcgatga tcgccccctt
961 actaggagat tatgaactgc aaggacctga ggaccttgca gtagaactgg tcccagtggt
1021 gatggggggg ataggtttgg tgctaggatt taccaaagag aaaattggaa agatgctatc
1081 atccgctgca tctactttga gagcttgtaa agaccttggt gcatacggac tggagatttt
1141 aaaattagtc atgaaatggt tcttcccaaa gaaagaggaa gaaaatgagt tagctatggt
1201 gagatccatc gaggatgcag tgttagacct cgaagcaatt gaaaacaatc acatgaccac
1261 cctgctcaaa gataaagaca gcttggcaac ctacatgaga acccttgacc ttgaggagga
1321 gaaagctaga aaactctcaa ccaaatctgc ttcacccgat attgtgggca caatcaacgc
1381 ccttctggca agaatcgctg ccgcacgctc cctagtgcat cgggcgaaag aagagctctc
1441 cagcaggccg agacctgtcg ttgtgatgat atcagggaaa ccagggatag gaaaaactca
1501 ccttgccagg gagttggcca agaagatcgc agcctccctc acaggggacc agcgtgtggg
1561 tcttatcccg cgcaatggtg ttgaccactg ggacgcatac aagggtgaaa gagtagtcct
1621 atgggacgac tatggaatga gcaaccccat ccatgacgcc ctcagattgc aggaacttgc
1681 tgacacttgc cccctcacgc taaattgtga cagaattgag aacaaaggga aagtctttga
1741 cagtgatgcc ataattatca ccaccaatct ggccaaccca gcaccactgg actatgtcaa
1801 cttcgaagcg tgctcgagac gcattgactt cctcgtgtac gcagaagctc cggaggtaga
1861 aagggcaaag cgtgacttcc caggtcaacc tgacatgtgg aagaacgctt tcagtcctga
1921 cttctcacac ataaaactgt cattggctcc acagggtggt tttgacaaga acggcaacac
1981 cccgcatgga aaaggtgtca tgaagaccct caccactggt tccctcatcg cccgagcatc
2041 agggctactc catgagagac tagatgaata tgaattgcaa ggcccagccc tcaccacttt
2101 caactttgat cgcaacaaga tacttgcttt tagacagctt gctgctgaaa acaagtatgg
2161 gctgatggat acaatgagag ttggaaaaca gctcaaggat gtcaagacta tgccagacct
2221 caaacaagca ctcaagaatg tcgcgatcag gaagtgccag atagtgtacg gtggtagcac
2281 ctacacactt gaggccgatg gtaagggtag tgtgaaaatt gacaaagtgc aaagtgctgc
2341 tgtgcaaact aacaatgaaa tagctggcgc cctacaccac ctaaggtgcg ccagaatcag
2401 atactatgtt aagtgtgtcc aggaggcatt gtattccatc attcaaatcg ctggggctgc
2461 attcgtcacc acgcgcatcg ctaagcgcat gaacatacag aatctctggt ccaggccaca
2521 ggtggaagac acagaagaga cggccagcaa agatggttgc ccaaaaccca aagaagatga
2581 agagtttgtt gtttcatccg acgacatcaa aactgaaggc aagaaaggga agaacaagtc
2641 tggtcgtggc aagaagcaca cagccttctc aagtaaaggg ctcagtgatg aggagtacga
2701 cgagtacaag agaatcagag aagaaaggaa tggcaagtat tccatagaag agtacctaca
2761 ggatagagac aagtactatg aggaggtggc tattgccagg gcaaccgaag aagacttctg
2821 tgaagaagaa gaggccaaaa tccggcagag aattttcaga ccaacaagga aacaacgcaa
2881 agaagagagg gcctctctcg gcttggtcac aggttctgaa atcagaaaga gaaacccaga
2941 cgactttaag cccaagggaa agctgtgggc tgatgatgac agaagtgttg actacaatga
3001 gaaactcaac tttgaggccc cgccaagcat ctggtcgcgg atagtcaact ttggttcagg
3061 ttggggtttc tgggtctccc ccagtctgtt cataacatca acccatgtca taccccaggg
3121 tgcaaaagag ttcttcggag tctctatcaa acaaatccag atacacaaat caggtgagtt
3181 ctgtcgatta agattcccaa aaccaatcag gactgatgtg acgggcatga ttctagaaga
3241 aggtgcgccc gaaggaaccg tggccacact gctcatcaag agaccaactg gagaactcat
3301 gcctctggca gccagaatgg gaacccatgc aaccatgaag attcaagggc gcacagttgg
3361 gggacaaatg ggtatgctcc tgacaggatc caacgccaag agcatggacc taggcacaac
3421 accaggtgac tgcggctgtc cctacatcta caagagaggg aatgactacg tggtcatagg
3481 ggtccacacg gccgctgccc gtggaggaaa cactgtcata tgtgccaccc aggggagtga
3541 gggggaagcc acacttgaag ggggtgataa caaaggaaca tactgtggtg caccaatctt
3601 gggcccaggg agtgctccaa agctcagcac caaaactaag ttttggaggt catccacaac
3661 accactcccg cctggcacct acgaaccagc ctacctcggt ggtaaagatc ccagagtcag
3721 aggtggccct tcattgcaac aagttatgag ggaccagcta aagccattca cagaacccag
3781 aggtaaacca ccaagaccaa atgtgttgga agctgccaag aaaaccatca tcaacgttct
3841 tgagcaaaca attgacccac cacaaaaatg gtcattctcg caagcttgcg catcccttga
3901 caaaaccacc tccagcggcc atccgcacca tatgcggaag aacgattgct ggaatgggga
3961 atccttcaca ggaagattgg cagatcaggc ctccaaggcc aacctaatgt ttgaagaggg
4021 aaagaacatg actccagtct acacaggtgc acttaaagat gaattggtaa agactgacaa
4081 aatttatggt aagatcaaga agaggcttct gtggggctca gacctggcga ccatgatacg
4141 gtgcgcccga gcttttggag gccttatgga tgaactcaag gcacactgtg tcactcttcc
4201 tgtcagagtt ggtatgaaca tgaatgagga tggccccatt atctttgaga aacattccag
4261 atataaatat cactatgatg ctgattattc ccggtgggac tcgacacaac aaagggatgt
4321 gctggcagca gcactagaaa ttatggttaa attctctcca gaaccacact tggctcaggt
4381 agttgcagaa gacctcctct ctcctagtgt aatggatgta ggtgactttc aaatatcaat
4441 aagtgagggg ctcccctctg gggtgccttg cacctcccag tggaactcca tcgcccactg
4501 gctcctcact ctttgtgcac tctctgaagt cacggacctg tcccctgata tcattcaggc
4561 caactccctt ttctccttct atggtgatga tgagattgtg agcacggaca taaagttgga
4621 cccagagaag ctgacagcaa aactcaagga gtacgggctg aaaccaaccc gtcccgacaa
4681 aactgaagga ccccttgtta tctctgaaga tctggatggc ctgacattcc tccggaggac
4741 tgtgacccgt gacccagctg gttggtttgg aaaattggaa caaagctcaa ttctcaggca
4801 aatgtactgg actaggggtc ccaaccatga agatccatct gaaacaatga taccacactc
4861 ccaaagaccc atacaattga tgtccttgct gggcgaggct gcactccacg gcccaacatt
4921 ttacagcaaa attagtaaat tggtcattgc agagttgaag gaaggtggta tggattttta
4981 cgtgcccaga caagagccaa tgttcagatg gatgaggttc tcagatctga gcacgtggga
5041 gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat gacgccgctc
5101 catctaatga tggtgccacg ggcctcgtcc cagagatcaa caacgagacc cttcctttgg
5161 aaccggtagc gggtgcagct attgccgcgc ctgttactgg ccaaaataat ataattgatc
5221 cctggattag aacaaatttt gtacaagcac ccaatgggga gttcacagtc tcacccagaa
5281 actctcctgg agaaattctt ctaaatttgg aattgggtcc tgatttaaat ccatatctgg
5341 cacatttatc tagaatgtat aatgggtacg ctggtggcgt agaagttcaa gtcctccttg
5401 cagggaatgc gttcactgca ggaaagattc tcttcgctgc cgttccacca aatttcccag
5461 ttgaattctt gagtcctgcg caaatcacca tgttgccaca cttaatagtt gatgttagaa
5521 cccttgaacc catcatgata ccactccctg atgtcaggaa caccttcttt cattacaata
5581 atcaacctgc caatcgcatg cgattggtag ccatgttgta cacccccctg agatctaatg
5641 gttctggtga tgatgttttc acagtgtcat gtagagtgct aactagaccc accccagatt
5701 ttgagtttac atatttggtc cccccttcgg tagagtctaa gactaaaccc ttttctctgc
5761 ccatactaac catctctgaa ttgaccaatt caagatttcc tgtaccggtg gattcattgt
5821 tcacagccca aaacaataat cttaatgttc aatgtcaaaa tggtcgctgc acattagatg
5881 gtgagttgca gggaaccact cagttgcaac catcaggcat ctgcgccttc agaggcaaaa
5941 taacggcaga tgtacgtcca aaccacgatg acagatggca tatgcaactg acaaatttca
6001 atggaacccc cttcgaccca acagaggatg tgccagctcc actgggcacc ccagatttta
6061 caggccttct cttcggagtg gcgagccaaa gaaatgttca acctaaccca aacaccacca
6121 gggcacatga agccgtgata tccacaacca gttcacagtt tgtgccaaaa ttaggatcaa
6181 tcaactttgg tagcacaagt gaagatttca ttgtgggcca gcccacaaaa ttcacaccag
6241 ttggcatcaa gattgaggat ggacatgcat ttgatcaatg gaccctaccc aggtattcag
6301 gccatttaac tctcaatatg aaccttgccc cacctgttgc cccaaatttc cctggtgaac
6361 aactactctt ctttaggtca aatgtcccct gtgccggcgg cattagtgat ggtgtcatcg
6421 actgcctgct gcctcaggag tggatacagc acttctacca ggagtctgct ccctcccagt
6481 ccgatgtggc cctgatcaga tacgtcaacc ccgacacggg ccgcacactt ttcgaggcga
6541 aactccatag aacaggctac atcactgttg ctcattcagg tgattatccc cttgttgtcc
6601 cctccaatgg atactttaga tttgattctt gggtgaatca attttattca cttgccccca
6661 tgggaactgg gaatgggcgc aggcgggtgc agtaatggca ggagctttca tagcaggtct
6721 agcaggtgac atgctcacca acacagttgg ctcactggcg aacgccgggg ccaatgccat
6781 cactcaaaag atagactttg aaaacaacaa acagctccaa tctgcctcct tccaacatga
6841 caaagacatg ctccaagcac aagtggctgc caccaagcag ttacaggctg atatgatcgc
6901 catcaagcag gggatactga ccgcgggcgg cttttcccct actgatgcgg cgagaggagc
6961 agtgggtgca cccatgacca aagtcctcga ctggtctggt actcgttact gggctccaaa
7021 ttccacgagg acaacaggtt actcagggca gttcacatca gcaccagtgc acatacccac
7081 aaaaatgatt cagcctactc ctgttaaaag gactcaacct ctttcttcct cttcaggtag
7141 tgcctatagt ctttcaacac agagcactgc cttgaccaag ccctcttcag gctcttcttc
7201 tgtttcttct gcttctacac aatctacaaa attgagttca gtttcttcaa tggatagaac
7261 agcaaattgg gtaaatcagc aaagaagcct cagccccttc atgagtggtg cactcaacat
7321 atctcatgta acacctccat cgagcagggc ttcgagttcg gggacagtct caactgtacc
7381 caaagaagtt ttggactcct ggacacctgc attcaacaca cgcagacagc cgctcttcgc
7441 acacctcaga gtgagggggg agtcacgtgt ttagtgaaaa gaattaatta gttttaatta
7501 aattttgttt gaatttaatt ttaattggat c
//