Typing tool
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Typing tool
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Complete norovirus genomes
| PV920378 | GII.17 | |
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|---|---|---|---|
| GII.P17 |
ORF1: 1..5102
ORF2: 5083..6699
ORF3: 6699..7478
LOCUS PV920378 7547 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2438/2022/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920378
VERSION PV920378.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7547)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7547)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7547
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2438/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jun-2022"
/note="genotype: GII.17[P17]"
gene <1..5102
/gene="ORF1"
CDS <1..5102
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XXN27333.1"
/translation="ASNDASVAVAGKNNNNDKEKSSSDNLFSNMTVTFKKALGARSKQ
PPSGETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQPD
AQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAIS
LAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGK
LKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSS
KSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAREL
AKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEK
AKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARA
SGLLHERMDEFELQGSGLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTL
DELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLR
SARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGC
PKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSP
SLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEG
TVVSILIKRTTGELMPLAVRMGTHATMKIQGRAVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPRLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGP
NHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQE
SMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..992
/gene="ORF1"
/product="p48"
mat_peptide 993..2090
/gene="ORF1"
/product="NTPase"
mat_peptide 2091..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RdRp"
gene 5083..6699
/gene="ORF2"
CDS 5083..6699
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27334.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDNDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6699..7478
/gene="ORF3"
CDS 6699..7478
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27335.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSFSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 tggcgtctaa cgacgcttcc gtcgccgttg ctggcaaaaa caacaacaac gacaaggaaa
61 aatcttcaag tgacaacttg ttttctaaca tgactgttac ttttaagaaa gccctcgggg
121 cgcggtctaa acagccgccc tcgggagaaa caaaacaaac acaaagacca ccaaggccac
181 cgacaccgga attggtgaag aagatacccc cacccccccc caatggcgag gatgaaccaa
241 agatagcgta taaggtggga gaaggtgtgt ctgggctgcc cgacttgaca accgtggcac
301 aacctgacgc acagaacaca gcctacagtg tccccccact tagccagaga gaggtcggcg
361 aagctaaaga accgttgcct ggctccattc tggaaatgtg ggatggtgag atctaccact
421 atgggctgta tgttgagcgg gggcatgtac tgggagtgca caaaccacct gccgcaataa
481 gccttgccaa aattgaatta acaccgctgt ctctctactg gagagtggtt tacactcctc
541 aatatttgat agctccagag acccttaaga atttaaatgg agaggctttc ccatacacgg
601 cctttgacaa caactgttat gccttctgtt gttgggtttt agacctcaac gactcctggc
661 ttagcagaag aatgatccaa agaacaactg gattcttcag accgtatcag gactggaaca
721 gaaaaccctt gccaaccatg gatgaaccaa aaatcaagaa ggccgcgaat gctgttctgt
781 gtgctctctc ctcactcttc actaggccca tcaaagatgt cattggaaag ctcaaaccac
841 tgaacattat gaacatactg gcaacttgtg attggacttt tgcgggcata gtggaatcca
901 tgatccttct tgctgagctc tttggggtgt tctggacgcc cccagatgtg tctgcaatga
961 ttgctccctt actcggtgac tacgagatgc aaggccccga agacctggcc gtggaacttg
1021 tgcccgtggt aatgggggga ataggtttgg tgttaggatt caccaaggaa aagatcggca
1081 agatgctttc atcagctgcg accacactca gggcctgcaa ggatctaggg tcttatgggt
1141 tggagatact caaactggtc atgaagtggt tcttccccaa gaaggaggag gccaacgagt
1201 tagccatggt gagggccatt gaggatgcag ttctggattt ggaggcaata gaaaacaatc
1261 acatgaccac tctccttaag gacaaagaca gcctggccac atacatgagg actcttgact
1321 tggaagaaga aaaagcaagg aaactgtcat ccaaatcggc gtcacctgac atcgtgggca
1381 cagtaaacgc attattggca aggatagcag ccgccaggtc actggtccac aaggctaagg
1441 aggagctctc gagcagacag aggcctgttg ttgtaatgat atcaggtagg ccaggtatag
1501 gaaagaccca tctggccaga gagctagcca agaaggttgc gtcaacactg tcaggcgacc
1561 aaaggattgg actgatacct agaaatggcg tcgaccattg ggacgcctac aaaggagagc
1621 gagtggttct gtgggatgac tatggcatga gcaaccctat acaggacgca ctgaggctcc
1681 aagaattggc tgacacctgt cctctgaccc taaattgtga caggattgaa aacaaaggaa
1741 aagtgttcga cagtgacgcc ataattataa caaccaacct cgcaaaccca gcaccactgg
1801 attatgtcaa ctttgaggct tgttctaggc gcatagactt cttggtgtat gcagacgcac
1861 ctgacatcga gaaggctaag cgtgacttcc ctggccaacc agatatgtgg aaagaccatt
1921 acagatcaga cttctcacac attaaacttc agctggcacc acagggaggc tttgataaga
1981 atggcaacac cccacatggc aaaggtgtgg ttaagtctct gacgattggt tctctgatcg
2041 ccagggcttc tggcttgctc catgagagaa tggatgaatt tgagctccaa ggctctggct
2101 taccaacctt caatttcgac cgtaacaaag tcgccgcctt cagacaattg gcagctgaaa
2161 acaaatatgg tcttatggac acactgaggg tcggcaacca actgaaaagt gtcaaaaccc
2221 tggatgagct gaagcaggct ataaagaaca tcaccatcaa gaagtgccag atagtgtaca
2281 atggatgcac ctacaccatg gaatctgatg ggaggaacaa ggttgtggtt gaaaaggttc
2341 aaaatgcaac agtccaaacc aacaatgaac ttgcaggagc actccaccac ctgagatctg
2401 caaggataag gtattatgtt aaatgtttcc aagaagctat ttactctcta ctccaaattg
2461 ctggtgcagc cttcgtcacc acacgcatcg tgaggcgcat gaacatctca aacctctggt
2521 cgaagccacc cgtcgaagag ggtgatgagc ctgaagacaa aggggggtgc cccaagccta
2581 gggatgaaga tgacctcact attgactcta aagacattaa agcagaaggg aagaagggca
2641 agaacaaatc tggccggggc aagaaacaca cagctttctc atccaagggc ctcagtgatg
2701 aagagtacga tgagtacaag agaatcaggg aggagaggaa tggcaaatac tcaattgaag
2761 aatacctcca ggatagggat agatactatg aagagcttgc cattgctaag gccactgagg
2821 aagacttctg tgaagaggag gaaatcaaaa ttcgccagag aatcttccgg cccaccagga
2881 agcaacggag agaggaaaga gccacgcttg ggcttgtcac aggatcggaa atcagaaaga
2941 ggaacccaga tgactttaag ccaaaaggaa aattgtgggc tgatgacaac agaagtgtgg
3001 actacaatga gaggatagat tttgaggctc ccccgagtgt ttggtctagg atagtcaact
3061 ttggtacagg atggggattc tgggtctccc caagtctctt tataacttca acacatgtca
3121 taccaaaagg aatcactgag gcctttggag ttcccattaa ccaaattcaa attcacaaat
3181 ctggagagtt ttgccgcttg cggtttccaa aaccaatcag gccagacgtg agtggaatga
3241 tcttggaaga gggtgcccct gaaggcactg ttgtgtccat tctcatcaag aggacaacag
3301 gggaactgat gcctctcgca gttagaatgg gaactcatgc cacaatgaaa atccaaggta
3361 gagcggtggg tggtcaaatg ggcatgcttc tcactggctc aaacgctaaa agcatggacc
3421 taggcacaac accaggtgac tgtgggtgcc catacatata caaaaggggc aatgacttcg
3481 tggtcattgg ggtgcacact gcagcagccc gtggaggcaa cacggtcata tgtgccacac
3541 agggaagtga aggcgaagcc accctcgaag gaggtgacaa caagggcacc tattgtggag
3601 cccccatctt gggacctggc aacgcaccaa gattgagcac aaaaacaaaa ttttggagat
3661 cttctaacgc gccgcttcct ccaggtacct atgaaccagc ataccttggt ggaaaagacc
3721 cgcgtgtgaa gggaggccca tctctacaac aagttatgag agaccaactt aaacctttta
3781 cagagcccag ggggaagcca ccaaaaccaa gtgtcctgga atcagcaaag aagaccatca
3841 ttaatgttct ggagcaaacc attgaccccc ctgaaaagtg gtcatatgcc caagcttgtg
3901 catccctcga caagacaacc tccagtggat acccgcatca cgtccggaag aatgactatt
3961 ggagtggtga atccttcacg gggaaacttg cagaccaggc ctcaaaagca aaccttatgt
4021 atgaggaagg caagcacatg caaccagttt acaccgcagc actcaaagac gagctcgtga
4081 aaactgacaa aatttatggc aagatcaaga aaagactcct gtggggctct gacctatcca
4141 ccatgattcg atgcgccagg gcatttggtg gcctcatgga tgagctcaaa gcaaattgta
4201 tcacactccc tgtcagagtt ggtatgaaca tgaatgaaga tggtcccata atatttgaaa
4261 agcactccag gtacaggtac cactatgatg ctgattactc ccgctgggat tccacacaac
4321 agcgggcagt gctggaagcg gcacttgaaa tcatggtgag attttctgct gagccacagt
4381 tggcacaaat agtggcagag gacctgctat caccaagtgt ggttgatgtg ggcgatttca
4441 aaattgttat caatgaaggc ctaccatctg gcgtgccttg cacttcacaa tggaactcca
4501 ttgcccactg gttactcacc ctgtgtgccc tgtctgaagt aacaggacta ggccctgaca
4561 tcatacaagc caactccatg tactctttct atggtgatga tgagatcgtg agcacagaca
4621 taaaattaga cccagagaaa ttgactgcaa aactcaaaga atatggtctt aaacccaccc
4681 ggcctgacaa gactgagggg ccactggtaa ttagtgagga cctgaatggg ttgactttcc
4741 tccgccgaac agtcacccgc gatccagcgg gttggtttgg aaagttggac caaaactcca
4801 tcctcaggca gctgtactgg acaaggggac ccaaccatga agaccccagt gagactatga
4861 taccacacgc acagagacct gtgcagctca tggcactgct aggagagtcc tccttacatg
4921 gaccctcatt ttacagcaag gttagcaagc tggtcatatc tgaacttaaa gagggaggaa
4981 tggattttta tgtgcccaga caagagtcaa tgttcaggtg gatgaggttc tcagatctaa
5041 gcacatggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
5101 gacgccgctc catctaatga tggtgctgct ggtctcgtac cagagggcaa taacgagacc
5161 cttcccctag aaccagttgc gggcgcagct atagccgcac ccgtcactgg ccaaaacaat
5221 ataattgacc cctggattag aacaaatttt gtgcaagcac caaatggaga gttcacagtg
5281 tcacccagaa actctcctgg agaaatttta ctaaacctag agttgggccc tgatttgaac
5341 ccttatttgg ctcatttgtc aaggatgtac aatgggtacg ctggtggagt tgaagtccag
5401 gttctcctgg cagggaacgc gttcactgcc gggaagatcc tcttcgccgc tgtcccgcca
5461 aatttcccag tggaattctt aagcccagcc cagattacaa tgctcccaca tataatagta
5521 gatgttagga ctcttgaacc aattatgatc ccattacctg atgttaggaa cacattcttc
5581 cactataata accagcccaa cagccgcatg agattagtgg ctatgctcta tacccccctt
5641 agatctaatg gctcaggtga tgatgttttc actgtttctt gcagggtttt gactaggcct
5701 actcctgatt ttgagttcac ttatctagtg ccaccctctg ttgaatctaa gactaagccc
5761 ttttccttac ccattttaac cctttctgag ctcacaaatt cgaggttccc ggtccccatt
5821 gattcgcttt tcaccgccca gaataatgtg ttgcaggtgc agtgtcaaaa tggcaggtgc
5881 acacttgacg gtgagctaca aggcacaacc cagttgctcc catctggcat ctgtgcgttc
5941 agaggacggg tgacagcaga aactgacaat cctgataagt ggcacatgca actgcaaaac
6001 ctcaatggca caacgtatga cccaactgat gatgtgccag ccccactggg tacacctgac
6061 ttcaagggcg tcgtgtttgg gatggcaagc caaagaaatg tgggtaacga tgcgcccggc
6121 tcaaccaggg ctcatgaggc ggtgatttca acctacagcc ccagatttgt tcccaaatta
6181 ggctctgtca attttaaaag taatgacaat gatttccaat tgcagccaac aagattcaca
6241 ccagtgggca ttaatgatga tggtgaccac ccgttcagac aatgggaact gccagactat
6301 tcaggggtgc ttaccttgaa tatgaacctt gcccccccgg ttgctccaaa tttccctggt
6361 gaacaattat tactcttcag atcttccgtg ccatgttcag gaggttacaa ccaaggtatt
6421 atagattgtc ttatccccca agaatggatc caacacttct accaggaatc agcaccttct
6481 cagtcagacg tggccctgat caggtacgtc aaccccgaca cgggtcgcac actgtttgag
6541 gcaaaattgc acagatctgg ctatatcact gtggctcact ctggagacta tcctcttgtt
6601 gttccggcta atggatactt tagatttgac tcttgggtaa atcagtttta ctcactcgcc
6661 ccaatgggaa ctgggaatgg gcgaaggagg gctcagtaat ggctggagct ttcattgcag
6721 gattggcggg tgacatgctc acgtcatccg tgggctccct ggtgaacgca ggggcaaacg
6781 ccatcagcca aaagatagac tttgaaaaca acaaacaact ccagtctgct tcctttcaac
6841 atgataaaga gatgctccaa gcgcaggtaa atgcaaccaa gcagctgcaa tctgagatga
6901 tagccctaaa acagggggtt ttggccgcag gcggcttttc ccccactgat gcagcgaggg
6961 gggccatcgg tgcacccatg acaaaggtgc ttgactggtc tggcactcga tattgggctc
7021 ccaattccac aaagacaact ggttattcgg ggcaattcac ctcttcacct gtgcacatgc
7081 ccagcccgag tgctccacaa tcaaaacccg caaagcccag atctctaggt tctttttctt
7141 cttctagtag tgtttatagt atgtctaccc aatcaacttc tctaacatct ggctcttcta
7201 gtaatgcttc ttctgcttct acaaaattga caaatttaag ctctggctcc tctcaaaaca
7261 ggacagcaga gtgggtgaac caacagagaa gtctcagccc tttcatgagt ggcgcactca
7321 atatctcaca tgtcacgcca ccttcaagta gggcctccag ttctgggacg gtctcaaccg
7381 tgcccaagga agttttggac tcctggacat ctgcattcaa cacacgcaga cagccgctct
7441 tcgcacacct cagagtgagg ggggagtcac gtgtttagtg aaaagaaata attggctata
7501 atatgatttc tttttaaaat ttggctaatt tgtatttctt ttaaaaa
//