Typing tool
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Typing tool
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Complete norovirus genomes
| PV920373 | GII.17 | |
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| GII.P17 |
ORF1: 1..5097
ORF2: 5078..6700
ORF3: 6700..7479
LOCUS PV920373 7535 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2506/2016/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920373
VERSION PV920373.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7535)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7535)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7535
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2506/2016/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Jul-2016"
/note="genotype: GII.17[P17]"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27318.1"
/translation="SNDASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQP
PPGETKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQPDA
QNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISL
AKIEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGKL
RPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPK
KEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELA
KKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCP
LTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKA
KRDFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARAS
GLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLD
ELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALNHLRS
ARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGCP
KPRDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPS
LFITSTHVIPKGIAEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGT
VVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGP
GNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPR
GKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYWS
GESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLS
TMIRCARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDS
TQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIELDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPN
HEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQES
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..987
/gene="ORF1"
/product="p48"
mat_peptide 988..2085
/gene="ORF1"
/product="NTPase"
mat_peptide 2086..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6700
/gene="ORF2"
CDS 5078..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27319.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICTFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6700..7479
/gene="ORF3"
CDS 6700..7479
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27320.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQTKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSPQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 tctaacgacg cttccgctgc cgttgctggc aaaaacaaca acaacgacaa ggaaaaatct
61 tcaagtgaca gcttgtttgc taacatgtct gtcactttta agaaagccct cggggcgcgg
121 tctaaacaac cgcccccggg agaaacaaaa caaatacaaa aaccaccaag gccaccgaca
181 ccggaattgg tgaagagaat acctccaccc ccacccaatg gcgaggatga accagggata
241 gtgtacaagg tgggagaggg tgtgtctggg ctgcccgacc taacaactgt ggtacaacct
301 gacgcacaaa acacagctta tagtgttccc ccacttagcc agagagaagt cggcgaagct
361 aaagaaccgc tgcctggctc cattctggaa atgtgggatg gtgagatcta ccactatggg
421 ctgtatgttg agcgggggca tgtgctcgga gtacacaaac cacctgctgc aataagcctt
481 gccaaaattg aaataacacc gctgtctctc tactggagag tggtctacac tccccagtat
541 ttgatagatc caggaactct taagaacttg agtggagaga ctttcccata cacggccttt
601 gacaacaact gttatgcctt ctgttgttgg gtcctagacc tcaacgactc ctggcttagc
661 aggagaatga tccaaagaac aactggattc ttcaaacctt atcaggattg gaacagaaaa
721 cccttaccaa ccatggatga accgaaaatt aagaaggccg cgaatgctgt cctatgcgct
781 ctctcctcac tcttcactag acccattaag gacatcattg gaaagcttag accactgaac
841 attcttaata tactggcaac ctgcgattgg acttttgcag gcatagtgga atccttgatc
901 cttcttgctg aactctttgg ggtgttctgg acacccccag atgtgtctgc gatgattgct
961 cccttactcg gtgactacga gatgcaaggc cccgaagacc tggccgtgga acttgtgccc
1021 gtggtgatgg gaggaatagg tttggtgtta ggattcacca aagaaaagat cggcaagatg
1081 ctttcatcag ctgcgaccac acttagggcc tgcaaggatc taggatctta tggattggag
1141 atactcaaat tggtcatgaa gtggttcttc cccaagaagg aggaggctaa cgaactagcc
1201 atggtgaggg ccattgagga tgcagtcctg gatttggagg caatagaaaa caatcacatg
1261 accacccttc tcaaggataa agacagcctg gccacataca tgaggactct tgacttggaa
1321 gaagagaaag caaggaaact gtcaaccaaa tcggcgtcac ctgacatcgt gggtacaata
1381 aacgcattat tggctaggat agcagccgcc aggtcactgg tccacaaggc taaggaggag
1441 ctctcgagca gacagagacc tgttgttgta atgatatcag gtagaccagg tataggaaag
1501 acccatttgg ccagagagct agccaagaaa gttgcgtcaa cactgtcagg cgaccaaagg
1561 attggactgg tacctagaaa tggcgtcgac cattgggacg cctacaaggg agagagggtg
1621 gtcctgtggg atgattatgg tatgagcaac cctatacagg acgcactgag gctccaagaa
1681 ttggccgaca cctgtcctct gaccctaaat tgtgatagga ttgaaaacaa aggaaaagtg
1741 ttcgacagtg atgccataat tataacaacc aaccttgcaa acccagcacc actagactat
1801 gtcaactttg aggcctgctc tagacgcata gacttcttgg tgtatgcaga cgcacctgac
1861 attgagaagg ctaagcgtga cttccctggc caaccagata tgtggaaaga ccatttcaga
1921 ccagacttct cacacattaa acttcagctg gcaccacagg gaggttttga caaaaatggc
1981 aacaccccac atggcaaagg tgtggtgaag tccctgacga ttggttctct gatcgccagg
2041 gcctccggct tgctccacga gagaatggat gaattcgagc tccaaggctc tgacctgcca
2101 accttcaatt ttgaccgcaa caaagtcgcc gccttcagac aattagcagc tgaaaacaaa
2161 tatggtctta tggacacatt gagggtcggc aaccaactga aaagtgttaa gaccctggat
2221 gagctgaagc aggccataaa gaacatcagt atcaagaagt gtcagatagt gtataatgga
2281 tgcacctata ccatggaatc tgatgggagg ggcaaggttg tggttgaaaa ggtacaaaac
2341 gcaacagttc aaaccaacaa tgaacttgta ggggcgctca accacctgag atctgcaagg
2401 ataagatact atgttaaatg tttccaagaa gccatttact ctctactcca aattgctggt
2461 gcagccttcg tcacctcacg catcgtgagg cgcatgaaca tatcaaacct ctggtcgaag
2521 ccacccatcg aggagggtga tgagcctgaa gacagaggag gatgccccaa gcccagggat
2581 gaagatgacc tcactattga ctctagagac attaaagtgg aagggaagaa gggcaagaac
2641 aagtctggcc ggggcaagaa acacacagcc ttctcttcca agggcctcag tgatgaagag
2701 tacgatgagt acaagagaat cagagaggag aggaatggca aatactcaat agaggaatac
2761 ctccaagata gggacagata ctatgaagag cttgccattg ctaaggccac tgaggaggac
2821 ttctgtgagg aggaggagat caaaatccgc cagagaatct tccgacccac caggaagcag
2881 cggaaagagg aaagggccac gcttgggctt gtcacaggat cggaaatcag aaagaggaat
2941 ccagatgact ttaaaccaaa aggaaaattg tgggctgatg acaacaggag cgtggattac
3001 aatgagagga tagattttga ggctcccccg agtgtttggt ctaggatagt caactttggc
3061 acaggctggg gattctgggt ttctccaagt ctctttataa cttcaacaca cgtcatacca
3121 aaaggaatcg ctgaggcctt tggagtgccc ataaaccaaa tccaaattca caaatctgga
3181 gaattttgcc gcttgcggtt tccaaagcca attagaccag acgtgagtgg gatgatcttg
3241 gaagagggcg cccctgaagg cactgttgtg tctattctca tcaaaaggac aacaggggag
3301 ctgatgcctc ttgcagtcag aatggggact catgccacaa tgaaaatcca aggtagaacg
3361 gtgggtggtc agatgggtat gcttctcact ggctcaaatg ctaaaagcat ggatctaggc
3421 acaacgccag gtgactgcgg atgtccatac atatacaaaa ggggcaatga ctttgtggtc
3481 attggggtgc acactgcagc agctcgtgga ggcaacacgg tcatatgtgc cacacaggga
3541 agtgaaggtg aagccactct tgaaggaggt gacaacaagg gtacctattg tggagccccc
3601 attttgggac ctggcaatgc accaaaattg agcacaaaga caaaattctg gagatcctct
3661 aacgcaccgc ttcccccagg tacttatgaa ccagcatacc ttggtgggag agacccgcgc
3721 gtgaagggag gcccatctct gcaacaagtt atgagagacc aacttaaacc ttttacagag
3781 cccagaggga agccaccaaa cccaaatgtc ttagagtcag caaagaagac tatcatcaat
3841 gttctggaac aaaccattga cccccctcaa aagtggtcat atgcccaagc ttgcgcatcc
3901 ctcgacaaga caacctccag tggatacccg caccacgtcc ggaagaatga ctattggagt
3961 ggtgaatcct tcacaggaaa acttgcagat caggcttcaa aagcaaatct catgtatgag
4021 gaaggcaagc acatgcaacc agtttacacc gcagcactta aagacgagct cgtgaaaact
4081 gacaaaattt atggcaaaat caagaaaaga ctcctgtggg gttctgacct ctccacaatg
4141 attcgatgcg ccagagcatt tggtggtctc atggatgaat tcaaagcaaa ttgtattaca
4201 ctccctatca gagttggtat gaatatgaat gaagatggtc ccataatatt tgagaaacac
4261 tccaggtaca ggtaccacta tgatgctgat tactcccgct gggactccac acaacagcgg
4321 gcagtgctgg aagcggcact tgaaatcatg gtgagatttt ctgctgagcc acagctggca
4381 caaatagtgg cagaggacct gctgtcacca agtgtggttg atgtgggcga tttcaaaatc
4441 gctatcaatg aaggcctacc atctggcgtg ccttgcacat cacaatggaa ttctattgcc
4501 cactggttac ttaccttgtg tgccctttct gaagtgacag gattaggtcc tgacatcata
4561 caagctaact ccatgtactc tttctatggt gatgatgaga ttgtgagcac agacatagaa
4621 ttggacccag agaaattgac cgcaaagctc aaagaatatg gccttaaacc cactcggccc
4681 gacaaaactg aggggccgtt ggtgattagt gaggacctga atgggttgac tttcctccgc
4741 cgaacagtca cccgtgatcc agcaggttgg tttggaaagt tggaccaaaa ctccatcctc
4801 aggcagttgt actggacaag aggacccaac catgaagacc ccagtgagac catgatacca
4861 cacgcacaaa gacctgtgca gctcatggca ctactaggag aatcctccct acatggaccc
4921 tcattttaca gcaaggttag caaattagtc atatctgaac ttaaagaggg aggaatggat
4981 ttttatgtgc ccagacaaga gtcaatgttc agatggatga ggttctcaga tctaagcaca
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgaatgacgc
5101 cgctccatct aatgatggtg ctgctggtct cgtaccagag ggcaacaacg agacccttcc
5161 cctagaacca gttgcgggcg cagctatagc cgcacccgtc actggccaaa ataatataat
5221 tgacccctgg attagaacaa attttgtgca agcaccaaat ggagagttca cagtgtcacc
5281 cagaaactct cctggagaaa ttttattaaa tttagagttg ggccctgatt tgaaccctta
5341 tttggctcat ttgtcaagga tgtacaatgg gtatgctggt ggagtggaag ttcaggttct
5401 cctggcaggg aacgcgttca ctgccggaaa gatcctcttc gccgccgtcc cgccaaattt
5461 cccagtggaa ttcttaagcc cagcccagat cacaatgctc ccacatttaa tagtagatgt
5521 taggactctt gaaccaatta tgatcccact ccctgatgtt aggaatacat tcttccatta
5581 tagtaaccag cctaacagcc gcatgagatt agtggctatg ctctataccc cactcagatc
5641 taatggctca ggtgatgatg tctttactgt ctcttgcagg gttttgacta ggcctactcc
5701 tgattttgag ttcacttatt tagtgccacc ttctgttgaa tctaaaacta agcctttttc
5761 cttacctatt ttaacccttt ctgagctcac aaattcgagg tttccagtcc ccatcgattc
5821 gcttttcacc gcccagaata atgtgttgca ggtgcagtgt caaaatggca ggtgtacact
5881 tgatggtgag ttacaaggca caacccagtt gctcccaact ggcatctgta cattcagagg
5941 acgggtgaca gcacaaatta accaacgtga caggtggcac atgcaactgc aaaacctcaa
6001 tggtacaaca tatgacccaa ctgatgatgt gccagccccg ctgggtacac ctgacttcaa
6061 gggcgtcgtg tttgggatgg taagccaaag aaatgtgggt aatgatgcgc ctggctcaac
6121 cagagcccaa caggcgtggg tttcaaccta tagcccccaa tttgtcccca aattaggttc
6181 tgtcaatctt agaattagtg ataatgatga tttccaattc cagccgacaa aattcacacc
6241 agtgggcgtc aatgatgacg atgatggcca cccgttcaga caatgggaac taccaaacta
6301 ttcaggggag cttaccttga atatgaatct tgccccccca gttgctccaa attttcctgg
6361 tgaacaattg ttattcttca gatctttcgt gccatgctca ggaggttaca atcaaggtat
6421 tatagattgt cttattcccc aagaatggat ccaacacttc tatcaggaat cagcaccctc
6481 ccagtcagac gtggccctga tcaggtatgt caaccccgat acgggacgta cactgtttga
6541 agcaaaattg cacagatctg gttacattac tgtggctcac tctggagact atcctcttgt
6601 tgttccggct aatggacact ttagatttga ttcttgggta aatcagtttt actcactcgc
6661 cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggggc tttcattgca
6721 ggattggcag gcgacatgct cacgtcatct gtgggctccc ttgtgaacgc aggggcaaac
6781 gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc ttcctttcag
6841 catgataaag agatgctcca agcgcaggtg agggcaacca agcagctgca atctgaaatg
6901 atagccctaa aacagggggt tttggccgca ggcggctttt cccccactga tgcagcaagg
6961 ggatccattg gtgcacccat gacaaaggtg cttgattggt ctggcactcg atactgggcg
7021 cccaattcca caaagacaac tggctattcg ggacaattca cctcttcacc tgtgcatatg
7081 tctagcccaa atgctccgca aacaaaacct gcaaagccta ggtctctagc tccttcctct
7141 tcttctagca gtgtctatag tatgtatact caatctactc atttaacatc tggctcttct
7201 agtaatgctt cttctgcctc cacaaaattg acaaatttaa gctctggctc ccctcaaaac
7261 agaacagcag agtgggtaaa tcaacagaga agtcttagcc ctttcatgag tggcgcactt
7321 aacatctcac atgtcacgcc accctcaagt agggcttcca gttctgggac ggtctcgacc
7381 gtgcccaagg aagttttgga ctcctggacg tctgcgttta acacacacag acagccgctc
7441 ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat aattggctat
7501 aatgtgattt ctttctaaat ttggctaatt tgtat
//