Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| PV920370 | GII.17 | |
|
|---|---|---|---|
| GII.PNA6 |
ORF1: 3..5111
ORF2: 5092..6705
ORF3: 6705..7475
LOCUS PV920370 7546 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2773/2022/UK nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION PV920370
VERSION PV920370.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7546)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7546)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7546
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2773/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Feb-2023"
/note="genotype: GII.17[PNA]"
gene 3..5111
/gene="ORF1"
CDS 3..5111
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27309.1"
/translation="MKMASNDASAAVAGKNNNNDNAKSSSDSLFSNMSVSFKKALGAR
PKQPPPGETKQQTKPPRPPTPELVKKIPPPPPNGEDEPIVTFKRGEGVSGLPDLTTVR
RPDVQNTAYSVPPLSLREVGEAKEPLPGAILEMWDGEIYHYGLYVERGHVLGVHKPPA
AVSIARIELTPLSLYWRVVYTPQYLISPDTLKNLDGESFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTKFFRPYQEWNRKPLPTMDEPKIKKVANALLCALSSLFTRPIKDI
IGKLRPLNILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKW
FFPKKEEADELAMVRAIEDAVLDLEAIENNHMTALLKDRDSLATYMKTLDLEEAKARK
LSTKSSSPDIVGTINALLARIAAARSLVHKAKEELSGRQRPVVVMISGRPGIGKTHLA
RELAKKIATSLAGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIPDALRLQELA
DTCTLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
VEKAKRDFPGQPDMWKEHYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLI
ARATGLLHERMDEFEFQGPELTTFNFDRNKIVAFRQLAAENKYGMMDTLRVGNQLKNV
KTMSELKQAIKNITIKKCQIVYGGCTYTMESDGHGKVTVDKVQSAVVQTNNELSGALH
HLRSARIRYYVKCFQEAVYSILQIAGAAFVTSRIVRRMNISNLWSKPPVEESDESEND
GGCPKPRDEDEITIDSRDIKAEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIARATDEDFCEEEEVKIRQRIFRPTRKQRKEERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYSERIDFEAPPSIWSRIVSFGSGWGFW
VSPSLFITSTHVIPKGITEAFGVPISQIQIHKSGEFCRLRFPKPIRTDVSGMILEEGA
PEGTVATILVKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKQPNPSVLEAAKQTIINVLEQTIDPPQRWTYAQACASLDKTTSSGHPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKAHCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLAAALEIMVRFSAEPNLAQIVAEDLLAPSVVDVGDFKITINEGLPSGV
PCTSQWNSISHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQIYWT
RGPNHEDPNETMIPHAQRPVQLMALLGESSLHGPSFYSKISKLVISELKEGGMDFYVP
RQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 3..1001
/gene="ORF1"
/product="p48"
mat_peptide 1002..2099
/gene="ORF1"
/product="NTPase"
mat_peptide 2100..2636
/gene="ORF1"
/product="p22"
mat_peptide 2637..3035
/gene="ORF1"
/product="VPg"
mat_peptide 3036..3578
/gene="ORF1"
/product="Pro"
mat_peptide 3579..5108
/gene="ORF1"
/product="RdRp"
gene 5092..6705
/gene="ORF2"
CDS 5092..6705
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27310.1"
/translation="MKMASNDAAPSNDGATGLVPEINHETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPAQRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNNLNVQCQNGRCTLDGELQGTT
QLLPSGICAFRGKITADVHGQHNDRWHMQLTNLNGTPFDPTEDVPAPLGSPDFTGLLY
GVASQRNPDNSTRAHEVVISTTSTQFVPKLGSINFGSESTDFQTNQPTKFTPVGIKME
DGHDFDQWALPKYSGHLTLNMNLAPPIAPNFPGEQLLFFRSNVPCAGGINAGIIDCLI
PQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVPA
NGYFRFDSWVNQFYSLAPMGTGNGRRRLQ"
gene 6705..7475
/gene="ORF3"
CDS 6705..7475
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27311.1"
/translation="MAGAFIAGLAGDMLTNAVGSLANAGANAITQKIDFENNKQLQSA
SFQHDKDMLQAQVAATKQLQADMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHMPVKQPTPVRKTQPPPSSSGSVYSLSTQSTSLPA
SSSSSSVSSASTQSTKLSSVSSMDRTANWVNQQRSLSPYMSGALNISHVTPPSSRASS
SGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 acttgaagat ggcgtctaac gacgcttccg ctgccgttgc tggcaaaaac aacaacaacg
61 acaacgcaaa atcttcaagt gacagcttgt tttctaacat gtctgtctct tttaagaaag
121 ccctcggggc gcggcctaaa cagccgcccc cgggagaaac aaaacaacaa actaaaccac
181 caagaccacc gacaccggaa ttggtgaaaa agataccacc acccccgcct aacggtgagg
241 atgaaccaat agtgaccttc aaacgtgggg agggcgtgtc tgggttgcct gacctaacaa
301 ctgtcaggcg gccagacgtg caaaacacag cttacagtgt tcctccactc agtctgaggg
361 aggttggtga agctaaagag ccactgcctg gtgccatttt ggaaatgtgg gatggtgaaa
421 tctaccacta tgggttgtat gtggagcgtg gtcacgtgct tggggtgcac aagccacctg
481 ctgcagtgag tatcgctagg attgaattga cacctttatc attatattgg agggtggttt
541 acacccccca gtatttgata tccccagaca ctctgaagaa cctggatggt gaatcatttc
601 cttacactgc atttgacaac aactgctacg ccttctgctg ttgggtcctc gacctcaatg
661 actcatggct tagcagaaga atgatccagc gaaccactaa gttctttagg ccttatcaag
721 aatggaacag aaagcccctg ccgaccatgg atgagcccaa gatcaagaag gttgcaaatg
781 ccttgttatg tgcactctcc tcgctcttca ccaggccaat caaagatatt attggaaaac
841 tcagaccatt gaacattctc aacatacttg ctacctgtga ttggaccttc gcaggcattg
901 tggaatccat gatccttcta gctgaacttt tcggggtgtt ctggacgccc ccagatgtgt
961 ctgctatgat tgccccctta ctcggtgatt acgagatgca aggccccgaa gacctggccg
1021 tcgagctcgt acccgtggtg atggggggaa taggcttggt gctcggattc accaaggaaa
1081 agatcggcaa gatgctatcg tcagctgctt ctacactcag agcctgcaaa gatttaggtg
1141 cctatggact ggagatactc aaactagtca tgaaatggtt tttcccaaag aaagaggagg
1201 ccgacgagct agctatggtg agggctatag aagacgctgt gttggatctg gaggcaatag
1261 aaaacaacca catgacagcc ctcctcaaag acagggacag cctggcaaca tatatgaaga
1321 cccttgacct agaagaggca aaagcaagaa aactctccac caaatcttct tctcctgata
1381 ttgtgggtac aataaatgca ctattggcaa ggattgcagc agccagatca ctggtacaca
1441 aagcaaagga ggaattgtca ggaagacaga ggcctgtagt ggtgatgata tctggaagac
1501 cgggcatagg aaagacccac ctcgcccggg agctggccaa gaagattgcc acgtcactag
1561 caggtgacca gagagtaggg ttagtgccca gaaatggtgt ggaccactgg gacgcctaca
1621 agggggagag agtggtgttg tgggacgatt atggcatgag caatccaata ccagatgcac
1681 tgagactcca ggagctggcc gacacctgca cactgaccct gaactgtgac aggatcgaaa
1741 acaaaggaaa ggtgtttgac agcgatgcca taattataac aactaacctt gcaaaccccg
1801 cgccgctgga ctacgtcaac ttcgaagcct gttccaggcg aatagacttc cttgtgtatg
1861 cagatgcacc agacgtagaa aaggccaagc gcgactttcc tgggcagcca gacatgtgga
1921 aagaacacta cagaccagac ttctcacaca tcaaactcca acttgcacca caagggggct
1981 ttgacaagaa tggcaacact ccgcatggta aaggtgtcat gaaatcctta acagtgggtt
2041 cactgattgc cagggccacc ggactactcc acgaaagaat ggatgagttc gaattccagg
2101 gtcccgaatt gacaactttc aatttcgacc gcaacaagat cgttgccttc agacaattgg
2161 cagctgagaa caagtacggc atgatggaca ccctaagagt tggcaaccaa ctgaagaatg
2221 ttaagaccat gagtgaactt aagcaggcca tcaagaatat taccatcaag aagtgtcaga
2281 tagtgtatgg tggatgcacc tacacgatgg agtctgatgg gcatggcaag gtgacagttg
2341 ataaggttca aagtgcagtg gttcaaacca acaatgagct ttcaggagct ctacaccacc
2401 ttaggtctgc aagaataagg tactatgtca aatgtttcca agaggcagtc tactccatac
2461 tacaaattgc tggtgcagca ttcgtcacct cacgcatcgt gaggcgcatg aacatctcaa
2521 acctctggtc aaagccacct gttgaagaga gtgatgaatc tgagaatgat ggagggtgcc
2581 ccaaacctag agacgaggat gagatcacaa tcgactctag ggacataaag gcagaaggaa
2641 agaaaggcaa gaacaagact ggccgtggta agaaacatac ggctttctct agcaagggac
2701 tcagtgatga agagtatgat gagtacaaga gaatcagaga agaaaggaat ggcaaatact
2761 caatagagga gtatcttcaa gacagggaca ggtactatga agagcttgcc attgccaggg
2821 ccactgatga ggacttctgt gaggaagagg aagtgaaaat ccgccaaagg atcttccggc
2881 ccaccaggaa acagcggaaa gaagaaaggg ccacgctggg actcgtcaca gggtcagaaa
2941 tcaggaaaag aaacccagat gatttcaaac caaaaggaaa attgtgggct gatgacaata
3001 ggagtgtgga ctacagtgaa aggatagact ttgaagcacc cccgagcatt tggtctagga
3061 tagtcagctt tggttcagga tgggggttct gggtttcccc aagtctcttc ataacatcaa
3121 cacatgtgat accgaagggt atcacggagg cctttggagt accaatcagc cagatccaga
3181 tccataaatc aggggagttt tgccgtctgc ggtttccaaa accaatcagg acagatgtaa
3241 gtggaatgat cttggaggag ggagctcccg agggaacagt tgcaaccatc cttgtcaaac
3301 ggccaactgg agagctgatg cccctcgcag ccaggatggg aacccatgcc acaatgaaaa
3361 tccaaggaag gacggttggc ggccaaatgg gcatgctcct gacaggctca aacgctaaga
3421 gcatggacct cggaacaaca ccaggtgact gtgggtgtcc ttacatatac aagagaggca
3481 atgactttgt ggttatcggt gtgcacacgg cagcagcacg cggaggcaac acagtcattt
3541 gtgccacaca aggaagtgaa ggtgaggcca ctcttgaggg aggtgacaac aaaggaactt
3601 actgtggggc tcccatttta ggacctggca atgcaccaaa attgagcacg aaaacgaaat
3661 tctggagatc ttccaacgca ccactcccac caggtaccta tgaaccagcc taccttggtg
3721 ggaaggatcc ccgcgtaaag ggaggcccat ctctgcaaca ggttatgaga gatcaactaa
3781 aacccttcac agagcccagg ggaaagcaac caaacccaag tgttcttgaa gcagccaaac
3841 aaaccataat caatgttctt gaacaaacca ttgatcctcc ccagagatgg acttacgctc
3901 aggcttgtgc atctcttgac aaaacaactt ccagcgggca cccccatcac gtccgcaaga
3961 atgactactg gagtggtgag tcttttacag gaaaattggc agatcaagct tcaaaggcaa
4021 acctcatgta cgaggagggt aaacacatga caccagtgta cactgcagca ctcaaagatg
4081 agctagtgaa gactgacaag atctatggaa agattaagaa aagactcttg tggggttcgg
4141 acctttcaac catgatacgg tgtgccaggg catttggtgg cttgatggat gaactcaaag
4201 cacactgtat aaccctccct gtaagagttg gcatgaacat gaatgaggac gggcccataa
4261 tatttgagaa acactccagg tacaggtacc actatgatgc tgactactct cgttgggact
4321 ccacacaaca aagagcagtg ctggcagcag cacttgaaat catggtgagg ttctcagcag
4381 aaccaaattt agcacaaata gtggctgagg acttgctggc accaagtgtg gttgacgtgg
4441 gtgacttcaa aatcacaata aatgagggtt taccctctgg tgtgccttgc acgtcacaat
4501 ggaattccat ctcccactgg ctactcacac tgtgtgccct gtcagaagtc actggtttag
4561 gtcctgacat catacaagca aattccatgt actctttcta tggtgatgat gaaattgtga
4621 gcactgacat caaacttgac ccagagaaat tgactgcaaa acttaaagaa tatggtctca
4681 aacccacccg tcccgacaag actgaggggc cattggtgat tagtgaagat ctgaacggac
4741 tgacattcct ccggcgaacg gtgacccgag atccagcagg ctggtttggg aagttagacc
4801 aaagctccat actcagacaa atttactgga ccagaggacc aaatcatgaa gatcccaatg
4861 agactatgat accacatgca caaaggcctg ttcagctcat ggcattgctg ggggagtcct
4921 ccttgcatgg accatcattc tatagcaaaa tcagcaaatt ggttatatct gaacttaaag
4981 aggggggaat ggatttttat gtgcccagac aagaacccat gttcagatgg atgagattct
5041 cagatttgag cacatgggag ggcgatcgca atctggctcc cagttttgtg aatgaagatg
5101 gcgtcgaatg acgccgctcc atctaatgat ggtgctacgg gcctcgtccc agagatcaac
5161 cacgagaccc ttcccctgga accagtggca ggcgcagcaa ttgccgcacc tgttactgga
5221 caaaacaaca taattgatcc ctggataaga acaaattttg tacaagcacc caacggagag
5281 ttcacagttt cacccagaaa ctctcccgga gaaattcttc taaatttgga gttaggtcct
5341 gatttgaacc cttatttggc acacctgtct agaatgtaca atgggtatgc tggtggtgtg
5401 gaagtccaag ttctcctggc ggggaatgcg ttcaccgcag gaaagatcct cttcgctgcc
5461 gtgccaccaa acttccccgt tgaattcttg agccccgccc aaattaccat gttgccacat
5521 ttgattgttg atgttagaac ccttgaacct atcatgatac cactccctga tgttaggaac
5581 accttctttc attacagtaa tcaacctgcc cagcgcatgc gcctagtggc catgttatat
5641 actcctttga gatctaatgg ttctggtgat gatgttttca ctgtctcttg cagggttctt
5701 actagaccca ccccagattt tgagttcaca tacttagtcc ctccttcagt agagtctaaa
5761 actaaaccct tttctctgcc tatcctgact atctctgagc ttactaactc tagattccct
5821 gcacctatag attcactgtt tacagcccaa aacaacaatc tcaatgtcca gtgccaaaat
5881 ggtaggtgca cgctagatgg tgagttgcaa gggactaccc agctgctgcc atcgggcata
5941 tgtgctttca gaggcaaaat aacagcagat gtgcacggcc agcacaatga cagatggcac
6001 atgcaattga caaatctcaa cgggacccca tttgatccaa cagaggatgt gccagccccc
6061 ctgggctccc cagacttcac aggccttctc tacggggtag ccagtcagag gaaccctgac
6121 aactccactc gggcacatga ggtcgtgatc tccacgacca gcacacagtt cgtgcccaaa
6181 ctgggatcaa tcaactttgg aagtgagagc actgatttcc aaacaaatca accaaccaag
6241 ttcacaccag ttggaatcaa gatggaagat gggcatgact ttgaccagtg ggccttgccc
6301 aagtattcag gccatttaac tctcaacatg aatctagccc cgcctattgc cccaaatttc
6361 cctggtgaac aattgctatt cttcagatca aatgtccctt gtgctggcgg tatcaacgct
6421 ggtattattg attgtctgat acctcaagag tggatacaac acttctacca agaatctgca
6481 ccatctcaat ctgatgtagc cctaatcagg tatgtcaacc ctgacacagg gcgcacactc
6541 ttcgaggcaa aacttcacag atctggctac attactgttg ctcattcagg tgattatcct
6601 cttgttgtcc ccgctaatgg atacttcaga tttgactctt gggtaaacca gttttactca
6661 cttgccccca tgggaacagg gaacgggcgc agacggttgc agtaatggct ggagctttta
6721 tagcaggtct tgcaggtgac atgctcacca atgcagtcgg ctcactggca aacgccgggg
6781 ccaatgctat aacccagaag atagattttg agaacaacaa acagctccaa tctgcctcct
6841 tccaacatga caaagacatg ctccaagcgc aagtggctgc aaccaaacag ctacaggctg
6901 acatgatcgc catcaagcag gggatactga ccgctggcgg cttttccccc actgatgcgg
6961 cgagaggagc agtgggtgca cccatgacca aggtcctaga ttggtctggc acccgctact
7021 gggcaccaaa ttccacaaaa acaaccagtt actcagggca attcacatca acgcctgtgc
7081 atatgcctgt caaacagccc actcccgtca gaaagaccca gccccctcct tcttcatctg
7141 gcagtgtcta tagcctttct acacagagca cttctttgcc tgcatcttct tctagttctt
7201 ctgtttcctc tgcttcaaca caatcaacaa aattaagttc agtttcctct atggatagaa
7261 cagcaaattg ggtgaatcag cagagaagcc ttagccccta catgagtggt gctcttaaca
7321 tctctcatgt aacacctcca tcaagcaggg cttcaagttc gggaacagtc tcaactgtac
7381 ccaaagaagt tttggactcc tggacgtctg cattcaacac acgcagacag ccgctcttcg
7441 cacacctcag agtgaggggg gagtcacgag tttagtgaaa agaatcaatt ggtttaaaat
7501 ttgattataa ttaggtctaa ttgagtcttt taaaaaaaaa aaaaaa
//