Typing tool
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Typing tool
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Complete norovirus genomes
| PV920369 | GII.17 | |
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|---|---|---|---|
| GII.PNA6 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7464
LOCUS PV920369 7525 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2825/2022/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920369
VERSION PV920369.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7525)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7525)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7525
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2825/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Dec-2022"
/note="genotype: GII.17[PNA]"
gene <1..5100
/gene="ORF1"
CDS <1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27306.1"
/translation="ASNDASAAVAGKNNNNDNAKSSSDSLFSNMSVSFKKALGARPKQ
PPPGETKQQTKPPRPPTPELVKKIPPPPPNGEDEPIVTFKRGEGVSGLPDLTTVRRPD
VQNTAYSVPPLSLREVGEAKEPLPGAILEMWDGEIYHYGLYVERGHVLGVHKPPAAVS
IARIELTPLSLYWRVVYTPQYLISPDTLKNLDGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTKFFRPYQEWNRKPLPTMDEPKIKKVANALLCALSSLFTRPIKDIIGK
LRPLNILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEADELAMVRAIEDAVLDLEAIENNHMTALLKDRDSLATYMKTLDLEEAKARKLST
KSSSPDIVGTINALLARIAAARSLVHKAKEELSGRQRPVVVMISGRPGIGKTHLAREL
AKKIATSLAGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPISDALRLQELADTC
TLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDVEK
AKRDFPGQPDMWKEHYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLIARA
TGLLHERMDEFEFQGPELTTFNFDRNKIVAFRQLAAENKYGMMDTLRVGNQLKNVKTM
SELKQAIKNITIKKCQIVYGGCTYTMESDGHGKVTVDKVQSAVVQTNNELSGALHHLR
SARIRYYVKCFQEAVYSILQIAGAAFVTSRIVRRMNISNLWSKPPVEESDESENDGGC
PKPRDEDEITIDSRDIKAEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIARATDEDFCEEEEVKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPKGITEAFGVPISQIQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEG
TVATILVKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKQPNPSVLEAAKQTIINVLEQTIDPPQRWTYAQACASLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDELKAHCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPNLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSISHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQIYWTRGP
NHEDPNETMIPHAQRPVQLMALLGESSLHGPSFYSKISKLVISELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27307.1"
/translation="MKMASNDAAPSNDGATGLVPEINHETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPAQRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNNLNVQCQNGRCTLDGELQGTT
QLLPSGICAFRGKITADVHGQHNDRWHMQLTNLNGTPFDPTEDVPAPLGSPDFTGLLY
GVASQRNPDNSTRAHEVVISTTSTQFVPKLGSINFGSESTDFQTNQPTKFTPVGIKME
DGHDFDQWTLPKYSGYLTLNMNLAPPIAPNFPGEQLLFFRSNVPCAGGINAGIIDCLI
PQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVPA
NGYFRFDSWVNQFYSLAPMGTGNGRRRLQ"
gene 6694..7464
/gene="ORF3"
CDS 6694..7464
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27308.1"
/translation="MAGAFIAGLAGDMLTNAVGSLANAGANAITQKIDFENNKQLQSA
SFQHDKDMLQAQVAATKQLQADMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHMPVKQPTPVRKTQPPPSSSGSVYSLSTQSTSLPA
SSSSSSVSSASTQSTKLSSVSSMDRTANWVNQQRSLSPYMSGALNISHVTPPSSRASS
SGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 gcgtctaacg acgcttccgc tgccgttgct ggcaaaaaca acaacaacga caacgcaaaa
61 tcttcaagtg acagcttgtt ttctaacatg tctgtctctt ttaagaaagc cctcggggcg
121 cggcctaaac agccgccccc gggagaaaca aaacaacaaa ctaaaccacc aagaccaccg
181 acaccggaat tggtgaaaaa gataccacca cccccgccta acggtgagga tgaaccaata
241 gtgaccttca aacgtgggga gggcgtgtct gggttgcctg acctaacaac tgtcaggcgg
301 ccagacgtgc aaaacacagc ttacagtgtt cctccactca gtctgaggga ggttggtgaa
361 gctaaagagc cactgcctgg tgccattttg gaaatgtggg atggtgaaat ctaccactat
421 gggttgtatg tggagcgtgg tcacgtgctt ggggtgcaca agccacctgc tgcagtgagt
481 atcgctagga ttgaattgac acctttatca ttatattgga gggtggttta caccccccag
541 tatttgatat ccccagacac tctgaagaac ctggatggtg aatcatttcc ttacactgca
601 tttgacaaca actgctacgc cttctgctgt tgggtcctcg acctcaatga ctcatggctt
661 agcagaagaa tgatccagcg aaccactaag ttctttaggc cttatcaaga atggaacaga
721 aagcccctgc cgaccatgga tgagcccaag atcaagaagg ttgcaaatgc cttgttatgt
781 gcactctctt cgctcttcac caggccaatc aaagatatta ttggaaaact cagaccattg
841 aacattctca acatacttgc tacctgtgat tggaccttcg caggcattgt ggaatccatg
901 atccttctag ctgaactttt cggggtgttc tggacgcccc cagatgtgtc tgctatgatt
961 gcccccttac tcggtgatta cgagatgcaa ggccccgaag acctggccgt cgagctcgta
1021 cccgtggtga tggggggaat aggcttggtg ctcggattca ccaaggaaaa gatcggcaag
1081 atgctatcgt cagctgcttc tacactcaga gcctgcaaag atttaggtgc ctatggactg
1141 gagatactca aactagtcat gaaatggttt ttcccaaaga aagaggaggc cgacgagcta
1201 gctatggtga gggctataga agacgctgtg ttggatctgg aggcaataga aaacaaccac
1261 atgacagccc tcctcaaaga cagggacagc ctggcaacat atatgaagac ccttgaccta
1321 gaagaggcaa aagcaagaaa actctccacc aaatcttctt ctcctgatat tgtgggtaca
1381 ataaatgcac tattggcaag gattgcagca gccagatcac tggtacacaa agcaaaggag
1441 gaattgtcag gaagacagag gcctgtagtg gtgatgatat ctggaagacc gggcatagga
1501 aagacccacc tcgcccggga gctggccaag aagattgcca cgtcactagc aggtgaccag
1561 agagtagggt tagtgcccag aaatggtgtg gaccactggg acgcctacaa gggggagaga
1621 gtggtgttgt gggacgatta tggcatgagc aatccaatat cagatgcact gagactccag
1681 gagctggccg acacctgcac actgaccctg aactgtgaca ggatcgaaaa caaaggaaag
1741 gtgtttgaca gcgatgccat aattataaca accaaccttg caaaccccgc gccgctggac
1801 tacgtcaact tcgaagcctg ttccaggcga atagacttcc ttgtgtatgc agatgcacca
1861 gacgtagaaa aggccaagcg cgactttcct gggcagccag acatgtggaa agaacattac
1921 agaccagact tctcacacat caaactccaa cttgcaccac aagggggctt tgacaagaat
1981 ggcaacactc cgcatggtaa aggtgtcatg aaatccttaa cagtgggttc actgattgcc
2041 agggccaccg gactactcca cgaaagaatg gatgagttcg aattccaggg tcccgaattg
2101 acaactttca atttcgaccg caacaagatc gttgccttca gacaattggc agctgagaac
2161 aagtacggca tgatggacac cctaagagtt ggcaaccaac tgaagaatgt taagaccatg
2221 agtgaactta agcaggccat caagaatatt accatcaaga agtgtcagat agtgtatggt
2281 ggatgcacct acacaatgga gtctgatggg catggcaagg tgacagttga taaggttcaa
2341 agtgcagtgg ttcaaaccaa caatgagctt tcaggagctc tacaccacct taggtctgca
2401 agaataaggt actatgtcaa atgtttccaa gaggcagtct actccatact acaaattgct
2461 ggtgcagcat tcgtcacctc acgcatcgtg aggcgcatga acatctcaaa cctctggtca
2521 aagccacctg ttgaagagag tgatgaatct gagaatgatg gagggtgccc caaacctaga
2581 gacgaggatg agatcacaat cgactctagg gacataaagg cagaaggaaa gaaaggcaag
2641 aacaagactg gccgtggtaa gaaacatacg gctttctcta gcaagggact cagtgatgaa
2701 gagtatgatg agtacaagag aatcagagaa gaaaggaatg gcaaatactc aatagaggag
2761 tatcttcaag acagggacag gtactatgaa gagcttgcca ttgccagggc cactgatgag
2821 gacttctgtg aggaggagga agtgaaaatc cgccaaagga tcttccggcc caccaggaaa
2881 cagcggaaag aagaaagggc cacgctggga ctcgtcacag ggtcagaaat caggaaaaga
2941 aacccagatg atttcaaacc aaaaggaaaa ttgtgggctg atgacaatag gagtgtggac
3001 tacaatgaaa ggatagactt tgaagcaccc ccgagcattt ggtctaggat agtcagcttt
3061 ggttcaggat gggggttctg ggtttcccca agtctcttca taacatcaac acatgtgata
3121 ccgaagggta tcacggaggc ctttggagta ccaatcagcc agatccagat ccataaatca
3181 ggggagtttt gccgtctgcg gtttccaaaa ccaatcagga cagatgtaag tggaatgatc
3241 ttggaggagg gagctcccga gggaacagtt gcaaccatcc ttgtcaaacg gccaactgga
3301 gagctgatgc ccctcgcagc caggatggga acccatgcca caatgaaaat ccaaggaagg
3361 acggttggcg gccaaatggg catgctcctg acaggctcaa acgctaagag catggacctc
3421 ggaacaacac caggtgactg tgggtgtcct tacatataca agagaggcaa tgactttgtg
3481 gttatcggtg tgcacacggc agcagcacgc ggaggcaaca cagtcatttg tgccacacaa
3541 ggaagtgaag gtgaggccac tcttgaggga ggtgacaaca aaggaactta ctgtggggct
3601 cccattttag gacctggcaa tgcaccaaaa ttgagcacga aaacaaaatt ctggagatct
3661 tccaacgcac cactcccacc aggtacctat gaaccagcct accttggtgg gaaggatccc
3721 cgcgtaaagg gaggcccatc tctgcaacag gttatgagag atcaactaaa acccttcaca
3781 gagcccaggg gaaagcaacc aaacccaagt gttcttgaag cagccaaaca aaccataatc
3841 aatgttcttg aacaaaccat tgatcctccc cagagatgga cttacgctca ggcttgtgca
3901 tctcttgaca aaacaacttc cagcgggtac ccccatcacg tccgcaagaa tgactactgg
3961 agtggtgagt cttttacagg aaaattggca gatcaagctt caaaggcaaa cctcatgtac
4021 gaggagggta aacacatgac accagtgtac actgcagcac tcaaagatga gctagtgaag
4081 actgacaaga tctatggaaa gattaagaaa agactcttgt ggggttcgga cctttcaacc
4141 atgatacggt gtgccagggc atttggtggc ttgatggatg aactcaaagc acactgtata
4201 accctccctg taagagttgg catgaacatg aatgaggacg ggcccataat atttgagaaa
4261 cactccaggt acaggtacca ctatgatgct gactactctc gttgggactc cacacaacaa
4321 agagcagtgc tggcagcagc acttgaaatc atggtgaggt tctcagcaga accaaattta
4381 gcacaaatag tggctgagga cttgctggca ccaagtgtgg ttgacgtggg tgacttcaaa
4441 atcacaataa atgagggttt accctctggt gtgccttgca cgtcacaatg gaattccatc
4501 tcccactggc tactcacact gtgtgccctg tcagaagtca ctggtttagg tcctgacatc
4561 atacaagcaa attccatgta ctctttctat ggtgatgatg aaattgtgag cactgacatc
4621 aaacttgacc cagagaaatt gactgcaaaa cttaaagaat atggtctcaa acccacccgt
4681 cccgacaaga ctgaggggcc attggtgatt agtgaagatc tgaacggact gacattcctc
4741 cggcgaacgg tgacccgaga tccagcaggc tggtttggga agttagacca aagctccata
4801 ctcagacaaa tttactggac cagaggacca aatcatgaag atcccaatga gactatgata
4861 ccacatgcac aaaggcctgt tcagctcatg gcattgctgg gggagtcctc cttgcatgga
4921 ccatcattct atagcaaaat cagcaaattg gttatatctg aacttaaaga ggggggaatg
4981 gatttttatg tgcccagaca agaacccatg ttcagatgga tgagattctc agatttgagc
5041 acatgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tctaatgatg gtgctacggg cctcgtccca gagatcaacc acgagaccct
5161 tcccctggaa ccagtggcag gcgcagcaat tgccgcacct gttactggac aaaacaacat
5221 aattgatccc tggataagaa caaattttgt acaagcaccc aacggagagt tcacagtttc
5281 acccagaaac tctcccggag aaattcttct aaatttggag ttaggtcctg atttgaaccc
5341 ttatttggca cacctgtcta gaatgtacaa tgggtatgct ggtggtgtgg aagtccaagt
5401 tctcctggcg gggaatgcgt tcaccgcagg aaagatcctc ttcgctgccg tgccaccaaa
5461 cttccccgtt gaattcttga gccccgccca aattaccatg ttgccacatt tgattgttga
5521 tgttagaacc cttgaaccta tcatgatacc actccctgat gttaggaaca ccttctttca
5581 ttacagtaat caacctgccc agcgcatgcg cctagtggcc atgttatata ctcctttgag
5641 atctaatggt tctggtgatg atgttttcac tgtctcttgc agggttctta ctagacccac
5701 cccagatttt gagttcacat acttagtccc tccttcagta gagtctaaaa ctaaaccctt
5761 ttctctgcct atcctgacta tctctgagct tactaactct agattccctg cacctataga
5821 ttcactgttt acagcccaaa acaacaatct caatgtccag tgccaaaatg gtaggtgcac
5881 gctagatggt gagttgcaag ggactaccca gctgctgcca tcgggcatat gtgctttcag
5941 aggcaaaata acagcagatg tgcacggcca gcacaatgac agatggcaca tgcaattgac
6001 aaatctcaac gggaccccat ttgatccaac agaggatgtg ccagcccccc tgggctcccc
6061 agacttcaca ggccttctct acggggtagc cagtcagagg aaccctgaca actccactcg
6121 ggcacatgag gtcgtgatct ccacgaccag cacacagttc gtgcccaaac tgggatcaat
6181 caactttgga agtgagagca ctgatttcca aacaaatcaa ccaaccaagt tcacaccagt
6241 tggaatcaag atggaagatg ggcatgactt tgaccagtgg accttgccca agtattcagg
6301 ctatttaact ctcaacatga atctagcccc gcctattgcc ccaaatttcc ctggtgaaca
6361 attgctattc ttcagatcaa atgtcccttg tgctggcggt atcaacgctg gtattattga
6421 ttgtctgata cctcaagagt ggatacaaca cttctaccaa gaatctgcac catctcaatc
6481 tgatgtagcc ctaatcaggt atgtcaaccc tgacacaggg cgcacactct tcgaggcaaa
6541 acttcacaga tctggctaca ttactgttgc tcattcaggt gattatcctc ttgttgtccc
6601 cgctaatgga tacttcagat ttgactcttg ggtaaaccag ttttactcac ttgcccccat
6661 gggaacaggg aacgggcgca gacggttgca gtaatggctg gagcttttat agcaggtctt
6721 gcaggtgaca tgctcaccaa tgcagtcggc tcactggcaa acgccggggc caatgctata
6781 acccagaaga tagattttga gaacaacaaa cagctccaat ctgcctcctt ccaacatgac
6841 aaagacatgc tccaagcgca agtggctgca accaaacagc tacaggctga catgatcgcc
6901 atcaagcagg ggatactgac cgctggcggc ttttccccca ctgatgcggc gagaggagca
6961 gtgggtgcac ccatgaccaa ggtcctagat tggtctggca cccgctactg ggcaccaaat
7021 tccacaaaaa caaccagtta ctcagggcaa ttcacatcaa cgcctgtgca tatgcctgtc
7081 aaacagccca ctcccgtcag aaagacccag ccccctcctt cttcatctgg cagtgtctat
7141 agcctttcta cacagagtac ttctttgcct gcatcttctt ctagttcttc tgtttcctct
7201 gcttcaacac aatcaacaaa attaagttca gtttcctcta tggatagaac agcaaattgg
7261 gtgaatcagc agagaagcct tagcccctac atgagtggtg ctcttaacat ctctcatgta
7321 acacctccat caagcagggc ttcaagttcg ggaacagtct caactgtacc caaagaagtt
7381 ttggactcct ggacgtctgc attcaacaca cgcagacagc cgctcttcgc acacctcaga
7441 gtgagggggg agtcacgagt ttagtgaaaa gaatcaattg gtttaaaatt tgattataat
7501 taggtctaat tgagtctttt aaaaa
//