Typing tool
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Typing tool
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Complete norovirus genomes
| PV920368 | GII.17 | |
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| GII.PNA6 |
ORF1: 1..5097
ORF2: 5078..6691
ORF3: 6691..7461
LOCUS PV920368 7541 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2837/2022/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920368
VERSION PV920368.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7541)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7541)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7541
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2837/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Dec-2022"
/note="genotype: GII.17[PNA]"
gene <1..5097
/gene="ORF1"
CDS <1..5097
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27303.1"
/translation="SNDASAAVAGKNNNNDNAKSSSDSLFSNMSVSFKKALGARPKQP
PPGETKQQTKPPRPPTPELVKKIPPPPPNGEDEPIVTFKRGEGVSGLPDLTTVRRPDV
QNTAYSVPPLSLREVGEAKEPLPGAILEMWDGEIYHYGLYVERGHVLGVHKPPAAVSI
ARIELTPLSLYWRVVYTPQYLISPDTLKNLDGESFPYTAFDNNCYAFCCWVLDLNDSW
LSRRMIQRTTKFFRPYQEWNRKPLPTMDEPKIKKVANALLCALSSLFTRPIKDIIGKL
RPLNILNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDL
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEADELAMVRAIEDAVLDLEAIENNHMTALLKDRDSLATYMKTLDLEEAKARKLSTK
SSSPDIVGTINALLARIAAARSLVHKAKEELSGRQRPVVVMISGRPGIGKTHLARELA
KKIATSLAGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPISDALRLQELADTCT
LTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDVEKA
KRDFPGQPDMWKEHYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLIARAT
GLLHERMDEFEFQGPELTTFNFDRNKIVAFRQLAAENKYGMMDTLRVGNQLKNVKTMS
ELKQAIKNITIKKCQIVYGGCTYTMESDGHGKVTVDKVQSAVVQTNNELSGALHHLRS
ARIRYYVKCFQEAVYSILQIAGAAFVTSRIVRRMNISNLWSKPPVEESDESENDGGCP
KPRDEDEITIDSRDIKAEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDRYYEELAIARATDEDFCEEEEVKIRQRIFRPTRKQRKEERATLGLVT
GSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSIWSRIVSFGSGWGFWVSPS
LFITSTHVIPKGITEAFGVPISQIQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGT
VATILVKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGP
GNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPR
GKQPNPSVLEAAKQTIINVLEQTIDPPQRWTYAQACASLDKTTSSGHPHHVRKNDYWS
GESFTGKLADQASKANLMYEEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLS
TMIRCARAFGGLMDELKAHCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDS
TQQRAVLAAALEIMVRFSAEPNLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTS
QWNSISHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKE
YGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQIYWTRGPN
HEDPNETMIPHAQRPVQLMALLGESSLHGPSFYSKISKLVISELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..987
/gene="ORF1"
/product="p48"
mat_peptide 988..2085
/gene="ORF1"
/product="NTPase"
mat_peptide 2086..2622
/gene="ORF1"
/product="p22"
mat_peptide 2623..3021
/gene="ORF1"
/product="VPg"
mat_peptide 3022..3564
/gene="ORF1"
/product="Pro"
mat_peptide 3565..5094
/gene="ORF1"
/product="RdRp"
gene 5078..6691
/gene="ORF2"
CDS 5078..6691
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27304.1"
/translation="MKMASNDAAPSNDGATGLVPEINHETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPAQRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNNLNVQCQNGRCTLDGELQGTT
QLLPSGICAFRGKITADVHGQHNDRWHMQLTNLNGTPFDPTEDVPAPLGSPDFTGLLY
GVASQRNPDNSTRAHEVVISTTSTQFVPKLGSINFGSESTDFQTNQPTKFTPVGITME
DGHDFDQWTLPKYSGHLTLNMNLAPPIAPNFPGEQLLFFRSNVPCAGGVNAGIIDCLI
PQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVPA
NGYFRFDSWVNQFYSLAPMGTGNGRRRLQ"
gene 6691..7461
/gene="ORF3"
CDS 6691..7461
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27305.1"
/translation="MAGAFIAGLAGDMLTNAVGSLANAGANAITQKIDFENNKQLQSA
SFQHDKDMLQAQVAATKQLQADMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHMPVKQPTPVRKTQPPPSSSGSVYSLSTQSTSLPA
SSSSSSVSSASTQSTKLSSVSSMDRTANWVNQQRSLSPYMSGALNISHVTPPSSRASS
SGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 tctaacgacg cttccgctgc cgttgctggc aaaaacaaca acaacgacaa cgcaaaatct
61 tcaagtgaca gcttgttttc taacatgtct gtctctttta agaaagccct cggggcgcgg
121 cctaaacagc cgcccccggg agaaacaaaa caacaaacta aaccaccaag accaccgaca
181 ccggaattgg tgaaaaagat accaccaccc ccgcctaacg gtgaggatga accaatagtg
241 accttcaaac gtggggaggg cgtgtctggg ttgcctgacc taacaactgt caggcggcca
301 gatgtgcaaa acacagctta cagtgttcct ccactcagcc tgagggaggt tggtgaagct
361 aaagagccac tgcctggtgc cattttggaa atgtgggatg gtgaaatcta ccactatggg
421 ttgtatgtgg agcgtggtca cgtgcttggg gtgcacaagc cacctgctgc agtgagtatc
481 gctaggattg aattgacacc tttatcatta tattggaggg tggtttacac cccccagtat
541 ttgatatccc cagacactct gaagaacctg gatggagaat catttcctta cactgcattt
601 gacaacaact gctacgcctt ctgctgttgg gtcctcgacc tcaatgactc atggcttagc
661 agaagaatga tccagcgaac cactaagttc tttaggcctt atcaagagtg gaacagaaag
721 cccctgccaa ccatggatga gcccaagatc aagaaggttg caaatgcctt gttatgtgca
781 ctctcttcgc tcttcaccag gccaatcaaa gatattattg gaaaactcag accattgaac
841 attctcaaca tacttgctac ctgtgattgg accttcgcag gcattgtgga atccatgatc
901 cttctagctg aacttttcgg ggtgttctgg acgcccccag atgtgtctgc tatgattgcc
961 cccttactcg gtgattacga gatgcaaggc cccgaagacc tggccgtcga gctcgtaccc
1021 gtggtgatgg ggggaatagg cttggtgctc ggattcacca aggaaaagat cggcaagatg
1081 ctatcgtcag ctgcttctac actcagagcc tgcaaagatt taggtgccta tggactggag
1141 atactcaaac tagtcatgaa atggtttttc ccaaagaaag aggaggccga cgagctagct
1201 atggtgaggg ctatagaaga cgctgtgttg gatctggagg caatagaaaa caaccacatg
1261 acagccctcc tcaaagacag ggacagcttg gcaacatata tgaagaccct tgacctagaa
1321 gaggcaaaag caagaaaact ctccaccaaa tcttcttctc ctgatattgt gggtacaata
1381 aatgcactat tggcaaggat tgcagcagcc agatcactgg tgcacaaagc aaaggaggaa
1441 ttgtcaggaa gacagaggcc tgtagtggtg atgatatctg gaagaccggg cataggaaag
1501 acccacctcg cccgggagct ggccaagaag attgccacgt cactagcagg tgaccagaga
1561 gtagggttag tgcccagaaa tggtgtggac cactgggacg cctacaaggg ggagagagtg
1621 gtgttgtggg acgattatgg catgagcaat ccaatatcag atgcactgag actccaggag
1681 ctggccgaca cctgcacact gaccctgaac tgtgacagga tcgaaaacaa aggaaaggtg
1741 tttgacagcg atgccataat tataacaact aaccttgcaa accccgcgcc gctggactac
1801 gtcaacttcg aagcctgttc caggcgaata gacttccttg tgtatgcaga tgcaccagac
1861 gtagaaaagg ccaagcgcga ctttcctggg cagccagaca tgtggaaaga acactacaga
1921 ccagacttct cacacatcaa actccaactt gcaccacaag ggggctttga caagaatggc
1981 aacactccgc atggtaaagg tgtcatgaaa tccttaacag tgggttcact gattgccagg
2041 gccaccggac tactccacga aagaatggat gagttcgaat tccagggtcc cgaattgaca
2101 actttcaatt tcgaccgcaa caagatcgtt gccttcagac aattggcagc tgagaacaag
2161 tacggcatga tggacaccct aagagttggc aaccaactga agaatgttaa gaccatgagt
2221 gaacttaagc aggccatcaa gaatattacc atcaagaagt gtcagatagt gtatggtgga
2281 tgcacctaca cgatggagtc tgatgggcat ggcaaggtga cagttgataa ggttcaaagt
2341 gcagtggttc aaaccaacaa tgagctttca ggagctctac accaccttag gtctgcaaga
2401 ataaggtact atgtcaaatg tttccaagag gcagtctact ccatactaca aattgctggt
2461 gcagcattcg tcacctcacg catcgtgagg cgcatgaaca tctcaaacct ctggtcaaag
2521 ccacctgttg aagagagtga tgaatctgag aatgatggag ggtgccccaa acctagagac
2581 gaggatgaga tcacaatcga ctctagggac ataaaggcag aaggaaagaa aggcaagaac
2641 aagactggcc gtggtaagaa acatacggct ttctctagca agggactcag tgatgaagag
2701 tatgatgagt acaagagaat cagagaagaa aggaatggca aatactcaat agaggagtat
2761 cttcaagaca gggacaggta ctatgaagag cttgccattg ccagggccac tgatgaggac
2821 ttctgtgagg aggaggaagt gaaaatccgc caaaggatct tccggcccac caggaaacag
2881 cggaaagaag aaagggccac gctgggactc gtcacagggt cagaaatcag gaaaagaaac
2941 ccagatgatt tcaaaccaaa aggaaaattg tgggctgatg acaataggag tgtggactac
3001 aatgaaagga tagactttga agcacccccg agcatttggt ctaggatagt cagctttggt
3061 tcaggatggg ggttctgggt ttccccaagt ctcttcataa catcaacaca tgtgataccg
3121 aaaggtatca cggaggcctt tggagtacca atcagccaga tccagatcca taaatcaggg
3181 gagttttgcc gtctgcggtt tccaaaacca atcaggacag atgtaagtgg aatgatcttg
3241 gaggagggag ctcccgaggg aacagttgca accatccttg tcaaacggcc aactggagag
3301 ctgatgcccc tcgcagccag gatgggaacc catgccacaa tgaaaatcca aggaaggacg
3361 gttggcggcc aaatgggcat gctcctgaca ggctcaaacg ctaagagcat ggacctcgga
3421 acaacaccag gtgactgtgg gtgtccttac atatacaaga gaggcaatga ctttgtggtt
3481 atcggtgtgc acacggcagc agcacgcgga ggcaacacag tcatttgtgc cacacaagga
3541 agtgaaggtg aggccactct tgagggaggt gacaacaaag gaacttactg tggggctccc
3601 attttaggac ctggcaatgc accaaaattg agcacgaaaa caaaattctg gagatcttcc
3661 aacgcaccac tcccaccagg tacctatgaa ccagcctacc ttggtgggaa ggatccccgc
3721 gtaaagggag gcccatctct gcaacaggtt atgagagatc aactaaaacc cttcacagag
3781 cccaggggaa agcaaccaaa cccaagtgtt cttgaagcag ccaaacaaac cataatcaat
3841 gttcttgaac aaaccattga tcctccccag agatggactt acgctcaggc ttgtgcatct
3901 cttgacaaaa caacttccag cgggcacccc catcacgtcc gcaagaatga ctactggagt
3961 ggtgagtctt ttacaggaaa attggcagat caagcttcaa aggcaaacct catgtacgag
4021 gagggtaaac acatgacacc agtgtacact gcagcactca aagatgagct agtgaagact
4081 gacaagatct atggaaagat taagaaaaga ctcttgtggg gttcggacct ttcaaccatg
4141 atacggtgtg ccagggcatt tggtggcttg atggatgaac tcaaagcaca ctgtataacc
4201 ctccctgtaa gagttggcat gaacatgaat gaggacgggc ccataatatt tgagaaacac
4261 tccaggtaca ggtaccacta tgatgctgac tactctcgct gggactccac acaacaaaga
4321 gcagtgttgg cagcagcact tgaaatcatg gtgaggttct cagcagaacc aaatttagca
4381 caaatagtgg ctgaggactt gctggcacca agtgtggttg acgtgggtga cttcaaaatc
4441 acaataaatg agggtttacc ctctggtgtg ccttgcacgt cacaatggaa ttccatctcc
4501 cactggctac tcacactgtg tgccctgtca gaagtcactg gtttaggtcc tgacatcata
4561 caagcaaatt ccatgtactc tttctatggt gatgatgaaa ttgtgagcac tgacatcaaa
4621 cttgacccag agaaattgac tgcaaaactt aaagaatatg gtctcaaacc cacccgtccc
4681 gacaagactg aggggccatt ggtgattagt gaagatctga acggactgac attcctccgg
4741 cgaacggtga cccgagatcc agcaggctgg tttgggaagt tagaccaaag ctccatactc
4801 agacaaattt actggaccag aggaccaaat catgaagacc ccaatgagac tatgatacca
4861 catgcacaaa ggcctgttca gctcatggca ttgctggggg agtcctcctt gcatggacca
4921 tcattctata gcaaaatcag caaattggtt atatctgaac ttaaagaggg gggaatggat
4981 ttttatgtgc ccagacaaga acccatgttc agatggatga gattctcaga tttgagcaca
5041 tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt cgaatgacgc
5101 cgctccatct aatgatggtg ctacgggcct cgtcccagag atcaaccacg agacccttcc
5161 cctggaacca gtggcaggcg cagcaattgc cgcacctgtt actggacaaa acaacataat
5221 tgatccctgg ataagaacaa attttgtaca agcacccaac ggagagttca cagtttcacc
5281 cagaaactct cccggagaaa ttcttctaaa tttggagtta ggtcctgatt tgaaccctta
5341 tttggcacac ctgtctagaa tgtacaatgg gtatgctggt ggtgtggaag tccaagttct
5401 cctggcgggg aatgcgttca ccgcaggaaa gatcctcttc gctgccgtgc caccaaactt
5461 ccccgttgaa ttcttgagcc ccgcccaaat taccatgttg ccacatttga ttgttgatgt
5521 tagaaccctt gaacctatca tgataccact ccctgatgtt aggaacacct tctttcatta
5581 cagtaatcaa cctgcccagc gcatgcgcct agtggccatg ttatatactc ctttgagatc
5641 taatggttct ggtgatgatg ttttcactgt ctcttgcagg gttcttacta gacccacccc
5701 agattttgag ttcacatact tagtccctcc ttcagtagag tctaaaacta aacccttttc
5761 tctgcctatc ctgactatct ctgagcttac taactctaga ttccctgcac ctatagattc
5821 actgtttaca gcccaaaaca acaatctcaa tgtccagtgc caaaatggta ggtgcacgct
5881 agatggtgag ttgcaaggga ctacccagct gctgccatcg ggcatatgtg ccttcagagg
5941 caaaataaca gcagatgtgc acggccagca caatgacaga tggcacatgc aattgacaaa
6001 tctcaacggg accccatttg atccaacaga ggatgtgcca gcccccctgg gctccccaga
6061 cttcacaggc cttctctacg gggtagccag tcagaggaac cctgacaact ccactcgggc
6121 acatgaggtc gtgatctcca cgaccagcac acagttcgtg cccaaactgg gatcaatcaa
6181 ctttggaagt gagagcactg atttccaaac aaatcaacca accaagttca caccagttgg
6241 aatcacaatg gaagatgggc atgactttga ccagtggacc ttgcccaagt attcaggcca
6301 tttaactctc aacatgaatc tagccccgcc tattgcccca aatttccctg gtgaacaact
6361 gctattcttc agatcaaatg tcccttgtgc tggcggtgtc aacgctggta ttattgattg
6421 tctgatacct caagaatgga tacaacactt ctaccaagaa tctgcaccat ctcaatctga
6481 tgtagcccta atcaggtatg tcaaccctga cacagggcgc acactcttcg aggcaaaact
6541 tcacagatct ggctacatta ctgttgctca ttcaggtgat tatcctcttg ttgtccccgc
6601 taatggatac ttcagatttg actcttgggt aaaccagttt tactcacttg cccccatggg
6661 aacagggaac gggcgcagac ggttgcagta atggctggag cttttatagc aggtcttgca
6721 ggtgacatgc tcaccaatgc agtcggctca ctggcaaacg ccggggccaa tgctataacc
6781 cagaagatag attttgagaa caacaaacag ctccaatctg cctccttcca acatgacaaa
6841 gacatgctcc aagcgcaagt ggctgcaacc aaacagctac aggctgacat gatcgccatc
6901 aagcagggga tactgaccgc tggcggcttt tcccccactg atgcggcgag aggagcagtg
6961 ggtgcaccca tgaccaaggt cctagattgg tctggcaccc gctactgggc accaaattcc
7021 acaaaaacaa ccagttactc agggcaattc acatcaacgc ctgtgcatat gcctgtcaaa
7081 cagcccactc ccgtcagaaa gacccagccc cctccttctt cttctggcag tgtctatagc
7141 ctttctacac agagcacttc tttgcctgca tcttcttcta gttcttctgt ttcctctgct
7201 tcaacacaat caacaaaatt aagttcagtt tcctctatgg atagaacagc aaattgggtg
7261 aatcagcaga gaagccttag cccctacatg agtggtgctc ttaacatctc tcatgtaaca
7321 cctccatcaa gcagggcttc aagttcggga acagtctcaa ctgtacccaa agaagttttg
7381 gactcctgga cgtctgcatt caacacacgc agacagccgc tcttcgcaca cctcagagtg
7441 aggggggagt cacgagttta gtgaaaagaa tcaattggtt taaaatttga ttataattag
7501 gtctaattga gtcttttaaa aaaaaaaaaa aaaaaaaaaa a
//