Typing tool
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Typing tool
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Complete norovirus genomes
| PV920367 | GII.17 | |
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|---|---|---|---|
| GII.P17 |
ORF1: 1..5055
ORF2: 5036..6652
ORF3: 6652..7431
LOCUS PV920367 7442 bp RNA linear VRL 30-SEP-2025
DEFINITION Norovirus GII isolate Hu/GII.17/WT-NORO-2857/2022/UK nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV920367
VERSION PV920367.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7442)
AUTHORS Tully,D.C., Roy,S., Tutill,H., Williams,R., Celma,C.,
Lindesmith,L.C., Baric,R.S. and Breuer,J.
TITLE Rapid evolution and global emergence of a novel, genetically
distinct GII.17 norovirus variant
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7442)
AUTHORS Tully,D.
TITLE Direct Submission
JOURNAL Submitted (11-JUL-2025) Infectious Diseases Epidemiology, London
School of Hygiene and Tropical Medicine, Keppel Street, London WC1E
7HT, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: CLC Genomics Workbench v. 11.0.01
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7442
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/WT-NORO-2857/2022/UK"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="United Kingdom"
/collection_date="Dec-2022"
/note="genotype: GII.17[P17]"
gene <1..5055
/gene="ORF1"
CDS <1..5055
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XXN27300.1"
/translation="NDKEKSSSDSLFSNMTVTFKKALGARSKQPPPGETKQTPRPPRP
PTPELVKKIPPPPPNGEDELKVVYKVGKGVSGLPDLTTVAQPDAQNTAYSVPPLSQRE
VGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIELTPLSLYWRV
VYTPQYLIDPETLKNLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFR
PYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLNIMNILATCDW
TFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPEDLVVELVPVVMGGIGL
VLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLIMKWFFPKKEEANELAMVRAIE
DAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSSKSASPDIVGTVNALL
ARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQRIG
LIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKV
FDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDH
YRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFELQG
SDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITIKKC
QIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQEAV
YSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTIDSKD
IKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYY
EELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGSEIRKRNPDDFKP
KGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPKGIT
EAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTGELM
PLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVV
IGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGLGNAPKLSTKTKFWR
SSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLESAKK
TIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQASK
ANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMD
ELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAALEIM
VRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCTSQWNSIAHWLLTLCA
LSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKTEGP
LVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPHAQR
PVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQEPMFRWMRFSDLSTWE
GDRNLAPSFVNEDGVE"
mat_peptide <1..945
/gene="ORF1"
/product="p48"
mat_peptide 946..2043
/gene="ORF1"
/product="NTPase"
mat_peptide 2044..2580
/gene="ORF1"
/product="p22"
mat_peptide 2581..2979
/gene="ORF1"
/product="VPg"
mat_peptide 2980..3522
/gene="ORF1"
/product="Pro"
mat_peptide 3523..5052
/gene="ORF1"
/product="RdRp"
gene 5036..6652
/gene="ORF2"
CDS 5036..6652
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XXN27301.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSYDDDFQLQPTRFTPVGIND
DDNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6652..7431
/gene="ORF3"
CDS 6652..7431
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XXN27302.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNMSHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 aacgacaagg aaaaatcttc aagtgacagc ttgttttcta acatgactgt tacttttaag
61 aaagccctcg gggcgcggtc taagcagccg cccccgggag aaacgaaaca aacaccaaga
121 ccaccaaggc caccgacacc ggaattggtg aagaagatac ccccaccccc ccccaatggc
181 gaggatgaac taaaggtagt gtacaaggtg ggaaaaggtg tgtctgggct gcccgactta
241 acaaccgtgg cacaacctga cgcacagaac acagcctata gtgtcccccc acttagccag
301 agagaggtcg gcgaagctaa agaaccgttg cctggctcca ttctggaaat gtgggatggt
361 gagatctacc actatgggct gtatgttgag cggggacatg tactgggagt gcacaaacca
421 cctgccgcaa taagccttgc caaaattgaa ttaacaccgc tgtctctcta ctggagagtg
481 gtttacactc cccagtactt gatagatcca gagaccctta agaatttaag tggagagact
541 ttcccataca cggcctttga caacaactgt tatgccttct gttgttgggt tttagatctc
601 aacgactcct ggcttagcag aagaatgatc caaagaacaa ccggattctt cagaccgtat
661 caggactgga acagaaaacc cttgccaacc atggatgaac caaaaatcaa aaaggccgcg
721 aatgctgttc tgtgtgctct ctcctcactc ttcactaggc ccatcaaaga tgtcattggg
781 aagcttaaac cactgaacat tatgaacata ctggcaactt gtgattggac ttttgcgggc
841 atagtggaat ccatgatcct tcttgctgag ctctttgggg tgttctggac gcccccagat
901 gtgtctgcaa taattgctcc cttactcggt gactacgaga tgcaaggccc cgaagacctg
961 gtcgtggaac ttgtgcccgt ggtaatggga ggaataggtt tggtgttagg attcaccaag
1021 gaaaagatcg gcaagatgct ttcatcagct gcgaccacac tcagggcctg caaggatcta
1081 ggatcttatg ggttggagat actcaaactg atcatgaagt ggttcttccc caagaaggag
1141 gaggccaacg agttagccat ggtgagggcc attgaggatg cagttctgga tttggaggca
1201 atagaaaaca accacatgac cactctcctt aaggacaaag acagcctggc cacatacatg
1261 agaactcttg acttggaaga agaaaaagca aggaaactgt catccaaatc ggcgtcacct
1321 gacatcgtgg gcacagtaaa cgcattattg gcaaggatag cagccgccag gtcgctggtc
1381 cacaaggcta aggaggagct ctcgagcaga cagaggcctg ttgttgtaat gatatcaggt
1441 aggccaggta taggaaagac ccatctggcc agagagctag ccaagaaggt tgcgtcaaca
1501 ctgtcaggcg accaaaggat tggactgata cctagaaatg gcgtcgacca ttgggacgca
1561 tacaaaggag agcgggtggt tctgtgggat gactatggca tgagtaaccc tatacaggac
1621 gctctgaggc tccaagaatt ggctgacacc tgtcctctga ccctaaattg tgacaggatt
1681 gaaaacaaag gaaaagtgtt cgacagtgac gccataatca taacaaccaa ccttgcaaac
1741 ccagcaccac tggattatgt caactttgag gcttgttcca gacgcataga cttcttggtg
1801 tatgcagacg cgcctgacat cgagaaggct aagcgtgact tccctggcca accagatatg
1861 tggaaagacc attacagatc agacttctca cacattaaac ttcagctggc accacaggga
1921 ggctttgata agaatggcaa caccccacat ggcaaaggtg tggttaagtc tctgacgatt
1981 ggttctctga tcgccagggc ttctggcttg ctccatgaga gaatggacga attcgaactc
2041 caaggttctg acttaccaac cttcaatttc gaccgtaaca aagtcgccgc cttcagacaa
2101 ttggcagctg aaaacaaata tggtcttatg gacacactga gggtcggcaa ccaactgaaa
2161 agtgtcaaaa ccctggatga gctgaagcag gctataaaga acatcaccat caagaagtgc
2221 cagatagtgt acaatggatg cacctacacc atggaatctg atgggaggaa caaggttgtg
2281 gttgaaaagg ttcaaaatgc aacagtccaa accaataatg aacttgcagg agcactccac
2341 cacctgagat ctgcaaggat aaggtattat gtcaaatgtt tccaagaagc tgtttactct
2401 ctactccaaa ttgctggtgc ggccttcgtc accacacgca tcgtgaggcg catgaacatc
2461 tcaaacctct ggtcgaagcc acccgttgaa gagggtgatg agcctgaaga caaagggggg
2521 tgccccaagc ccagggatga agatgacctc actattgact ccaaagacat taaagcagaa
2581 gggaagaagg gcaagaacaa atctggccgg ggcaagaaac acacagcttt ctcatccaag
2641 ggcctcagtg atgaagagta cgatgagtac aagagaatca gggaggagag gaatggcaaa
2701 tactcgatag aggaatacct ccaggatagg gatagatact atgaagagct tgccattgct
2761 aaggccactg aggaagactt ctgtgaagag gaggaaatca aaattcgcca gagaatcttc
2821 cggcccacca ggaagcaacg gagagaggaa agagccacgc ttgggcttgt cacaggatcg
2881 gaaatcagaa agaggaatcc agatgacttt aagccaaaag gaaagttgtg ggctgatgac
2941 aacagaagtg tggactacaa tgagaggata gattttgagg ctcccccgag tgtttggtct
3001 aggatagtca actttggtac aggatgggga ttctgggtct ccccaagtct ctttataact
3061 tcaacacatg tcataccaaa aggaatcact gaggcttttg gagtccccat taaccaaatt
3121 caaattcaca aatctggaga gttttgccga ttgcggtttc caaaaccaat caggccagac
3181 gtgagtggaa tgatcttgga agagggtgcc cctgaaggca ctgttgtgtc cattctcatc
3241 aagaggacaa caggggaact gatgcctctc gcagttagaa tgggaactca tgccacaatg
3301 aaaatccaag gtagaacggt gggcggtcaa atgggcatgc ttctcactgg ctcaaacgct
3361 aaaagcatgg acctaggcac aacaccaggt gactgtgggt gcccatacat atacaaaagg
3421 ggcaatgact tcgtggtcat tggggtgcac actgcagcag cccgtggagg caacacggtc
3481 atatgtgcca cacagggaag tgaaggcgaa gccaccctcg aaggaggtga caacaagggc
3541 acctattgtg gagcccccat cttgggactt ggcaacgcac caaaattgag cacaaaaaca
3601 aaattctgga gatcttctaa cgcgccgctt cctccaggca cctatgaacc agcatacctt
3661 ggtggaaaag acccgcgtgt gaagggaggc ccatctctac aacaggttat gagagaccaa
3721 ctcaagcctt ttacagagcc cagagggaag ccaccaaaac caagtgtcct agaatcagca
3781 aagaagacca tcatcaatgt tctagaacaa accattgacc cccctgaaaa gtggtcatat
3841 gcccaagctt gtgcatccct cgacaagaca acctccagtg gatacccaca tcacgtccgg
3901 aagaatgatt attggagtgg cgaatccttc acggggaaac ttgcagacca ggcctcaaaa
3961 gcaaacctta tgtatgagga aggcaagcac atgcaaccag tttacactgc agcactcaaa
4021 gacgagctcg tgaaaactga caaaatttat ggcaagatca agaaaagact cctgtggggc
4081 tctgacctat ccaccatgat tcgatgcgct agggcatttg gtggcctcat ggatgagctc
4141 aaggctaatt gtatcacact ccctatcaga gttggtatga acatgaatga ggatggtccc
4201 ataatatttg aaaagcactc caggtacagg taccactatg atgctgatta ctcccgctgg
4261 gattccacac aacagcgggc agtgctggaa gcggcacttg aaatcatggt gagattttct
4321 gctgagccac agttggcaca aatagtggca gaggacctgc tatcaccaag tgtggttgat
4381 gtgggcgatt tcaaaattgc tatcaatgaa ggcctaccat ctggcgtgcc ctgcacttca
4441 caatggaatt ctattgccca ctggttactc accctgtgtg ccctgtctga agtaacagga
4501 ctaggccctg acatcataca agccaactcc atgtactctt tctatggtga tgatgagata
4561 gtgagcacag acataaaatt agacccagag aaattgactg caaaactcaa agaatatggt
4621 cttaaaccca cccggcctga caagactgag gggccactgg taattagtga ggacctgaat
4681 gggttgactt tcctccgccg aacagtcacc cgcgatccag cgggttggtt tggaaagttg
4741 gaccaaaact ccatcctcag gcagctgtac tggacaaggg gacccaacca tgaagacccc
4801 agtgagacca tgataccaca cgcacagaga cctgtgcagc tcatggcact gctaggagag
4861 tcctccctac atggaccctc attttacagc aaggttagca agctggtcat atctgaactt
4921 aaagaggggg gaatggattt ttatgtgccc agacaagagc caatgttcag atggatgagg
4981 ttctcagatc taagcacatg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa
5041 gatggcgtcg aatgacgccg ctccatctaa tgatggtgct gctggtctcg taccagaggg
5101 caataacgag acccttcccc tagaaccagt tgcgggcgca gctatagccg cacccgtcac
5161 tggccaaaac aatataattg acccctggat tagaacaaat tttgtgcaag caccaaatgg
5221 agagttcaca gtgtcaccca gaaactctcc tggagaaatt ttactaaacc tagagttggg
5281 ccctgatttg aacccttatt tggctcattt gtcaaggatg tacaatgggt atgctggtgg
5341 agttgaagtc caggttctcc tggcggggaa cgcgttcact gccgggaaga tcctcttcgc
5401 cgctgtcccg ccaaatttcc cagtggaatt cttaagccca gcccagatta caatgctccc
5461 acatataata gtagatgtta ggactcttga accaataatg atcccattac ctgatgttag
5521 gaatacattc ttccattata ataaccagcc caacagccgc atgagattag tggctatgct
5581 ctataccccc cttagatcta atggctcagg tgatgatgtt ttcactgttt cttgcagggt
5641 tttgactagg cccacccctg attttgagtt cacttatcta gtgccaccct ctgttgaatc
5701 taagactaag cccttttcct tacccattct aaccctttct gagctcacaa attcgaggtt
5761 cccggtcccc attgattcgc ttttcaccgc ccagaacaat gtgttgcagg tgcagtgtca
5821 aaatggcagg tgcacacttg acggtgagct acaaggcaca acccagctgc tcccatctgg
5881 catctgcgcg ttcagaggac gggtgacagc agaaaccgac aatcctgaca agtggcacat
5941 gcaattgcaa aacctcaatg gcacaacata tgacccaact gatgatgtgc cagccccact
6001 gggtacacct gacttcaagg gcgtcgtgtt tggaatggca agccaaagaa atgtgggtaa
6061 cgatgcgccc ggctcaacca ggtcccatga ggcggtaatt tcaacctaca gccccagatt
6121 tgttccaaaa ttaggctctg tcaattttaa aagttatgac gatgatttcc aattgcagcc
6181 aacaagattc acaccagtgg gcattaatga tgatgacaac cacccgttca gacaatggga
6241 attgccagac tattcagggg tgcttacctt gaatatgaac cttgctcccc cggttgctcc
6301 aaatttccct ggtgaacaat tattattctt cagatcttct gtgccatgtt caggaggtta
6361 caaccaaggt attatagatt gtcttatccc ccaagaatgg atccaacact tctaccagga
6421 atcagcacct tctcagtcag acgtggccct gatcaggtac gtcaaccccg acacgggtcg
6481 cacactgttt gaggcaaaat tgcatagatc tggctatatc actgtggctc actctggaga
6541 ctatcctctt gttgttccgg ctaatggata ctttagattt gactcttggg taaatcagtt
6601 ttactcactc gccccaatgg gaactgggaa tgggcgaagg agggctcagt aatggctgga
6661 gctttcattg caggattggc gggtgacatg ctcacgtcat ccgtgggctc cctggtgaac
6721 gcaggggcaa acgccatcaa ccaaaagata gactttgaaa acaacaaaca actccagtct
6781 gcttcctttc aacatgacaa agagatgctc caagcgcagg tgaatgcaac caagcagctg
6841 caatctgaga tgatagccct aaaacagggg attttggccg caggcggctt ttcccccact
6901 gatgcagcga ggggggccgt cggtgcaccc atgacaaagg tgcttgactg gtctggcact
6961 cgatattggg ctcctaattc cacaaagaca actggttatt cggggcaatt cacctcttca
7021 cctgtgcaca tgcccagccc gagtgctcca caatcaaaac ccgcaaagcc caggtctcta
7081 ggttcctctt cttcttctag tagtgtttat agtatgtcta cccaatcaac ttctctaaca
7141 tctggctctt ctagtaatgc ttcttctgct tctacaaaat tgacaaattt aagctccggc
7201 tcctctcaaa acagaacagc agagtgggtg aaccaacaga gaagtctcag ccctttcatg
7261 agtggcgcac tcaatatgtc acatgtcacg ccaccttcaa gtagggcctc cagttctggg
7321 acggtctcaa ccgtgcccaa ggaggttttg gactcctgga catctgcatt caacacacgc
7381 agacagccgc tcttcgcaca cctcagagtg aggggggagt cacgtgttta gtgaaaagaa
7441 at
//