Typing tool
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Typing tool
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Complete norovirus genomes
| PV784298 | GII.17 | |
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| GII.P17 |
ORF1: 5..5113
ORF2: 5094..6710
ORF3: 6710..7489
LOCUS PV784298 7555 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate Hu/GII.17/140/DE/2023, complete genome.
ACCESSION PV784298
VERSION PV784298.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7555)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7555)
AUTHORS Jacobsen,S., Altmann,B. and Niendorf,S.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2025) Infectious diseases, Robert Koch-Institute,
Seestr. 10, Berlin 13353, Germany
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) HIVE-hexagon aligner v.
2.1; High-performance Integrated Virtual
Environment (HIVE) HIVE-heptagon profiler
v. 2.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7555
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/140/DE/2023"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Germany"
/collection_date="29-Jun-2023"
/note="genotype: GII.17"
gene 5..5113
/gene="ORF1"
CDS 5..5113
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XVJ37716.1"
/translation="MKMASNDASVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
SKQPPPGETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRATGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRFYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVAIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..1003
/gene="ORF1"
/product="p48"
mat_peptide 1004..2101
/gene="ORF1"
/product="NTPase"
mat_peptide 2102..2638
/gene="ORF1"
/product="p22"
mat_peptide 2639..3037
/gene="ORF1"
/product="VPg"
mat_peptide 3038..3580
/gene="ORF1"
/product="Pro"
mat_peptide 3581..5110
/gene="ORF1"
/product="RdRp"
gene 5094..6710
/gene="ORF2"
CDS 5094..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XVJ37717.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDNDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XVJ37718.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKPRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgtcgccgtt gctggcaaaa acaacaacaa
61 cgacaaggaa aaatcttcaa gtgacagctt gttttctaac atgactgtta cttttaagaa
121 agccctcggg gcgcggtcta aacagccgcc cccgggagaa acaaaacaaa cacaaagacc
181 accaaggcca ccgacaccgg aattggtgaa gaagataccc ccaccccccc ccaatggcga
241 ggatgaacca aagatagcgt ataaggtggg agaaggtgtg tctgggctgc ccgacttgac
301 aaccgtggca caacctgacg cacagaacac agcctacagt gtccccccac ttagccagag
361 agaggtcggc gaagctaaag aaccgttgcc tggctccatt ctggaaatgt gggatggtga
421 gatctaccac tatgggctgt atgttgagcg ggggcatgta ctgggagtgc acaaaccacc
481 cgccgcaata agccttgcca aaattgaatt aacaccgctg tccctctact ggagagtggt
541 ttacactccc caatatttga tagctccaga gacccttaag aatttaaatg gagaggcttt
601 cccatacacg gcctttgaca acaactgtta tgccttctgt tgttgggttt tagacctcaa
661 cgactcctgg cttagcagaa gaatgatcca aagagcaact ggattcttca gaccgtatca
721 ggactggaac agaaaaccct tgccaaccat ggatgaacca aaaattaaga aggccgcgaa
781 tgctgttctg tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa
841 gctcaaacca ctgaacatta tgaacatatt ggcaacttgt gattggacct ttgcgggcat
901 agtggaatcc atgatccttc ttgctgagct ctttggggtg ttctggacgc ccccagatgt
961 gtctgcaatg attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
1021 cgtggaactt gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga
1081 aaagatcggc aagatgcttt catcagctgc gaccacactc agggcctgta aggatctagg
1141 atcttatggg ttggagatac tcaaactggt catgaagtgg ttcttcccta agaaggagga
1201 ggccaatgag ttagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat
1261 agaaaacaac cacatgacca ctctccttaa ggacaaagac agcctggcca catacatgag
1321 gactcttgac ttggaagaag aaaaagcaag gaaactgtca tccaaatcgg cgtcacctga
1381 catcgtgggc acagtaaatg cattattggc aaggatagca gccgccaggt cactggtcca
1441 caaggctaag gaggagctct cgagcagaca gaggcctgtt gttgtaatga tatcaggtag
1501 gccaggtata ggaaagaccc atctggccag agagctagcc aagaaggttg cgtcaacact
1561 gtcaggcgac caaaggattg gactgatacc tagaaatggc gtcgaccatt gggacgccta
1621 caaaggagag cgggtggttc tgtgggatga ctatggcatg agcaacccca tacaggacgc
1681 actgaggctc caagaattgg ctgacacctg tcccctgacc ctaaattgtg acaggattga
1741 aaacaaagga aaagtgttcg acagtgacgc cataattata acaaccaacc ttgcaaaccc
1801 agcaccactg gattatgtca actttgaggc ttgttctaga cgcatagact tcttggtgta
1861 tgcagacgca cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg
1921 gaaagaccat tacagatcag acttctcaca cattaaactt cagctggcac cacagggagg
1981 ctttgataag aatggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg
2041 ttctctgatc gccagggctt ctggcttgct ccatgagaga atggatgaat ttgagctcca
2101 aggctctgac ttaccaacct tcaatttcga ccgtaacaag gtcgccgcct tcagacaatt
2161 ggcagctgaa aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2221 tgtcaaaacc ctggatgagc tgaagcaggc tataaagaac atcaccatca agaagtgcca
2281 gatagtgtac aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt
2341 tgaaaaggtt caaaatgcaa cagtccaaac caacaatgag cttgcaggag cactccacca
2401 cctgagatct gcaaggataa ggtattatgt taaatgtttc caagaagcta tttactctct
2461 actccaaatt gctggtgcag ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc
2521 aaacctctgg tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg
2581 ccccaagccc agggatgaag atgacctcac tattgattct aaagacatta aagcagaagg
2641 gaagaagggc aagaacaaat ctggtcgggg caagaaacac acagctttct catccaaggg
2701 cctcagtgat gaagagtacg atgagtacaa gagaattagg gaggagagga atggcaaata
2761 ctcaattgaa gaatacctcc aggacaggga tagattctat gaagagcttg ccattgctaa
2821 ggccactgag gaagacttct gtgaagagga ggagatcaaa attcgccaga ggatcttccg
2881 gcccaccagg aagcaacgga gagaggaaag agccacgctt gggcttgtca caggatcgga
2941 aatcagaaag aggaacccag atgacttcaa gccaaaagga aaattgtggg ctgatgacaa
3001 cagaagtgtg gactacaatg agaggataga ttttgaggct cccccgagtg tttggtctag
3061 gatagtcaac tttggtacag gatggggatt ctgggtctcc ccaagtctct ttataacttc
3121 aacacatgtc ataccaaaag gaatcactga ggcctttgga gttcccatta accaaattca
3181 aattcacaaa tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt
3241 gagtggaatg atcttggaag agggtgcccc tgaaggcact gttgtgtcca ttctcatcaa
3301 gaggacaaca ggggaactga tgcctctcgc agttagaatg ggaactcatg ccacaatgaa
3361 aatccaaggt agaacggtgg gtggtcaaat gggcatgctt ctcactggct caaacgctaa
3421 aagcatggac ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg
3481 caatgacttc gtggccattg gggtgcacac tgcagcagcc cgtggaggca acacggtcat
3541 atgtgccaca caggggagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac
3601 ctattgtgga gcccccatct tgggacctgg caacgcacca aaattaagca caaaaacaaa
3661 attctggaga tcttctaacg cgccgcttcc tccaggtacc tatgaaccag cataccttgg
3721 tggaaaagac ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact
3781 taaacctttt acagagccca gagggaagcc accaaaacca agtgtcctag aatcagcaaa
3841 gaagaccatc attaatgttc tggagcaaac cattgaccct cctgaaaagt ggtcatatgc
3901 ccaagcttgt gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa
3961 gaatgactat tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc
4021 aaaccttatg tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga
4081 cgagctcgtg aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc
4141 tgacctatcc accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa
4201 agcaaattgt atcacactcc ctgtcagagt tggtatgaac atgaatgaag atggtcccat
4261 aatatttgaa aagcactcca ggtacaggta ccactatgat gctgattact cccgctggga
4321 ttccacacaa cagcgggcag tgctggaggc ggcacttgaa atcatggtga gattttctgc
4381 tgagccacag ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt
4441 gggcgatttc aaaattgtta tcaatgaagg cctaccatct ggcgtgcctt gcacttcaca
4501 atggaattct attgcccact ggttgctcac cctgtgtgcc ctgtctgaag taacaggact
4561 aggccctgac atcatacaag ccaactccat gtactctttc tatggtgatg atgagattgt
4621 gagcacagac ataaaattag acccagagaa attgactgca aaactcaaag aatatggtct
4681 taaacccacc cggcctgaca agactgaggg gccactggta attagtgagg acctgaacgg
4741 gttgactttc ctccgccgaa cagtcacccg cgatccagct ggttggtttg gaaagttgga
4801 ccaaaactcc atcctcaggc agctgtactg gacaagggga cccaaccatg aagaccccag
4861 tgagactatg ataccacacg cacagagacc tgtgcagctc atggcactgc taggagagtc
4921 ctccctacat ggaccctcat tttacagcaa ggttagcaag ctggtcatat ctgaacttaa
4981 agagggagga atggattttt atgtgcccag acaagagtca atgttcaggt ggatgaggtt
5041 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
5101 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5161 ataacgagac ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg
5221 gccaaaacaa tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5281 agttcacagt gtcacccaga aactctcctg gagaaatttt actaaatcta gagttgggcc
5341 ctgatttgaa cccttatttg gctcatttgt caaggatgta caatgggtac gctggtggag
5401 ttgaagtcca ggttctcctg gcagggaacg cgttcactgc cgggaagatc ctcttcgccg
5461 ctgtcccgcc aaatttccca gtggaattct taagcccagc ccagattaca atgctcccac
5521 atataatagt agatgttagg actcttgaac caattatgat cccattacct gatgttagga
5581 atacattctt ccattataac aatcagccca atagccgcat gagattagtg gctatgctct
5641 atacccccct tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt
5701 tgactagacc tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta
5761 aaactaagcc cttttcctta cccattttaa ccctttctga gctcacaaat tcgaggttcc
5821 cggtccccat tgattcgctt ttcaccgccc agaataatgt gttgcaggtg cagtgtcaaa
5881 atggcaggtg cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca
5941 tctgtgcgtt cagaggacgg gtgacagcag aaactgacaa ccctgataag tggcacatgc
6001 aactgcaaaa cctcaatggc acaacgtatg acccaactga tgatgtgcca gccccactgg
6061 gtacacctga cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg
6121 atgcgcccgg ctcaactagg gctcatgagg cggtgatttc aacctacagc ccaagatttg
6181 tccccaaatt aggctctgtt aattttaaaa gtaatgacaa tgatttccaa ttgcagccaa
6241 caagattcac accagtgggc attaatgatg atggcgacca cccgttcaga caatgggaac
6301 tgccagacta ttcaggggtg cttaccttga atatgaacct tgcacccccg gttgctccaa
6361 atttccctgg tgaacaatta ttactcttca gatcttccgt gccatgttca ggaggttaca
6421 accaaggtat tatagattgt cttatccccc aagaatggat ccaacacttc taccaggaat
6481 cagcaccttc tcagtcagac gtggccctga tcaggtacgt caaccccgac acgggtcgca
6541 cactgtttga ggcaaaattg catagatctg gttatatcac tgtggctcac tctggagact
6601 atcctcttgt tgtcccggct aatggatact ttagatttga ttcttgggta aaccagtttt
6661 actcactcgc cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc
6721 tttcattgca ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc
6781 aggggcaaat gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccaatctgc
6841 ttcctttcaa catgataaag agatgctcca agcgcaggta aatgcaacca agcagctgca
6901 atctgaaatg atagccctaa aacagggggt tttggccgca ggcggctttt cccccaccga
6961 tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg cttgattggt ctggcactcg
7021 atattgggct cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc
7081 tgtgcacatg cccagcccga gtgctccaca atcaaaaccc gcaaagccca gatctctagg
7141 ttcttcttct tcttctagta gtgtttatag tatgtctacc caatcaactt ctctaacatc
7201 tggctcttct agtaatgctt cttctgcttc tacaaaattg acaaatttaa gctctggctc
7261 ctctcaaaac aggacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag
7321 tggcgcactc aatatctcac atgtcacgcc accttcaagt agggcctcca gttctgggac
7381 ggtctcaacc gtgcccaagg aagttttgga ctcctggaca tctgcattca acacacgcag
7441 acagccgctc ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat
7501 aattggctat aatatgattt ctttaaaatt taaatttggc taatttgtat ctttt
//