Typing tool
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Typing tool
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Complete norovirus genomes
| PV784287 | GII.17 | |
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| GII.P17 |
ORF1: 5..5113
ORF2: 5094..6710
ORF3: 6710..7489
LOCUS PV784287 7555 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate Hu/GII.17/129/DE/2023, complete genome.
ACCESSION PV784287
VERSION PV784287.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7555)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7555)
AUTHORS Jacobsen,S., Altmann,B. and Niendorf,S.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2025) Infectious diseases, Robert Koch-Institute,
Seestr. 10, Berlin 13353, Germany
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) HIVE-hexagon aligner v.
2.1; High-performance Integrated Virtual
Environment (HIVE) HIVE-heptagon profiler
v. 2.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7555
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/129/DE/2023"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Germany"
/collection_date="19-Jan-2023"
/note="genotype: GII.17"
gene 5..5113
/gene="ORF1"
CDS 5..5113
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XVJ37689.1"
/translation="MKMASNDASVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGAR
SKQPPPGETKQTQRPPRPPTPELVKKIPPPTPNGEDEPKITYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDL
NDSWLNRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLTGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELTGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTVDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMRIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..1003
/gene="ORF1"
/product="p48"
mat_peptide 1004..2101
/gene="ORF1"
/product="NTPase"
mat_peptide 2102..2638
/gene="ORF1"
/product="p22"
mat_peptide 2639..3037
/gene="ORF1"
/product="VPg"
mat_peptide 3038..3580
/gene="ORF1"
/product="Pro"
mat_peptide 3581..5110
/gene="ORF1"
/product="RdRp"
gene 5094..6710
/gene="ORF2"
CDS 5094..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XVJ37690.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6710..7489
/gene="ORF3"
CDS 6710..7489
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XVJ37691.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKSRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgtcgccgtt gctggcaaaa acaacaacaa
61 cgacaaggaa aaatcttcaa gtgacagctt gttttctaac atgactgtta cttttaagaa
121 agccctcggg gcgcggtcta aacagccgcc cccgggagaa acaaaacaaa cacaaagacc
181 accaaggcca ccgacaccgg aattggtgaa gaagataccc ccacccaccc ccaatggcga
241 ggatgaacca aagataacgt ataaggtggg agaaggtgtg tctgggctgc ccgacttgac
301 aaccgtggca caacctgacg cacagaatac agcctacagt gtccccccac ttagccagag
361 agaggtcggc gaagctaaag aaccgttgcc tggatccatt ctggaaatgt gggatggtga
421 gatctaccac tatgggctgt atgttgagcg ggggcatgta ctgggagtgc acaaaccacc
481 tgccgcaata agccttgcca aaattgaatt aacaccgctg tctctctact ggagagtggt
541 ttacactccc cagtatttga tagctccaga gaccctcaag aatttaaatg gagaggcttt
601 cccatacacg gcctttgaca acaactgtta tgccttctgt tgttgggttt tagacctcaa
661 cgactcctgg cttaacagaa gaatgatcca aagaacaact ggattcttca gaccgtatca
721 ggactggaac agaaaaccct tgccaaccat ggatgaacca aaaatcaaga aggccgcgaa
781 tgctgttctg tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa
841 gctcaaacca ttgaacatca tgaatatact ggcaacttgt gactggacct ttgcgggcat
901 agtggaatcc atgatccttc ttgctgagct ctttggggtg ttctggacgc ccccagatgt
961 gtctgcaatg attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
1021 cgtagaactt gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga
1081 aaagatcggc aagatgcttt catcagctgc gaccacactc agggcctgta aggatctagg
1141 atcttatggg ttggagatac tcaaactggt catgaagtgg ttcttcccca agaaggagga
1201 ggccaacgag ttagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat
1261 agaaaacaac cacatgacca ctctccttaa ggacaaagac agcctggcca catacatgaa
1321 gactcttgac ttggaagaag aaaaagcaag gaaactgtca tccaaatcgg cgtcacctga
1381 catcgtgggc acagtaaatg cattattggc aaggatagca gccgccaggt cactggtcca
1441 caaggctaag gaggagctct cgagcagaca gaggcctgtt gttgtaatga tatcaggtag
1501 gccaggtata ggaaagaccc atttggccag agagctagcc aagaaggttg cgtcaacact
1561 gacaggcgac caaaggattg gactgatacc tagaaatggc gtcgaccatt gggacgccta
1621 caaaggagag cgggtggttc tgtgggatga ctatggcatg agcaacccta tacaggacgc
1681 actgaggctc caagaattgg ctgacacctg tcctctgacc ctaaattgtg acaggattga
1741 aaacaaagga aaagtgttcg acagtgacgc cataattata acaaccaacc tcgcaaaccc
1801 agcaccactg gattacgtca actttgaggc ttgttctaga cgcatagact tcttggtgta
1861 tgcagacgca cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg
1921 gaaagaccat tacagatcag acttctcaca catcaaactc cagctggcac cacagggagg
1981 ctttgataag aatggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg
2041 ttctctgatc gccagggctt ctggcttgct ccatgagaga atggatgaat ttgagctcca
2101 aggctctgac ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt
2161 ggcagctgaa aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2221 tgtcaaaacc ctggatgagc tgaagcaggc tataaagaac atcaccatca agaagtgcca
2281 gatagtgtac aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt
2341 tgaaaaggtt caaaatgcaa cagtccaaac caacaatgaa cttacaggag cactccacca
2401 cctaaggtct gcaaggataa ggtattatgt taaatgtttc caagaagcta tttactctct
2461 actccaaatt gctggtgcag ccttcgtcac cacacgcatt gtgaggcgca tgaacatctc
2521 aaacctctgg tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg
2581 ccccaagccc agggatgaag atgacctcac tgttgactct aaagacatta aagcagaagg
2641 gaagaagggc aagaacaaat ctggccgggg caagaagcac acagctttct catccaaggg
2701 cctcagtgat gaagagtacg atgagtacaa gagaatcagg gaggagagga atggcaaata
2761 ctcaattgaa gaatacctcc aggacaggga tagatactat gaagagcttg ccattgctaa
2821 ggccactgag gaagacttct gtgaagagga ggaaatcaaa attcgccaga gaatcttccg
2881 gcccaccagg aagcaacgga gagaggaaag agccacgctt gggcttgtca cagggtcgga
2941 aatcagaaag aggaacccag atgactttaa gccaaaagga aaattgtggg ctgatgacaa
3001 cagaagtgta gactacaatg agaggataga ttttgaggct cccccgagtg tttggtccag
3061 gatagtcaac tttggtacag gatggggatt ctgggtctcc ccaagtctct ttataacttc
3121 aacacatgtc ataccaaaag gaatcactga ggcctttgga gttcccatta accaaattca
3181 aattcacaaa tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt
3241 gagtggaatg atcttggaag agggtgcccc tgaaggcact gttgtgtcca ttctcatcaa
3301 gaggacaaca ggggaactga tgcctctcgc agttaggatg gggacccatg ccacaatgag
3361 aatccaaggt agaacggtgg gtggtcaaat gggcatgctt ctcactggct caaacgctaa
3421 aagcatggac ctaggcacga caccgggtga ctgtgggtgc ccatacatat acaaaagggg
3481 caatgacttc gtggtcattg gggtgcacac tgcagcagcc cgtggaggca acacggtcat
3541 atgtgccaca cagggaagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac
3601 ctattgtgga gcccccatct tgggacctgg caacgcacca aaattaagca caaaaacaaa
3661 attctggaga tcttccaacg cgccgcttcc tccaggtacc tatgaaccag cataccttgg
3721 tggaaaagac ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact
3781 taaacctttt acagagccaa gagggaagcc accaaaacca agtgtcctag aatcagcaaa
3841 gaagaccatc attaatgttc tggagcaaac cattgacccc cctgaaaagt ggtcatatgc
3901 ccaagcttgt gcatccctcg acaagacaac ctccagtgga tacccgcatc acgtccggaa
3961 aaatgactat tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc
4021 aaaccttatg tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga
4081 cgagctcgtg aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc
4141 tgacctatct accatgattc gatgcgccag ggcatttggt ggcctcatgg atgagctcaa
4201 agcaaattgt atcacactcc ctgtcagagt tggtatgaat atgaatgaag atggtcccat
4261 aatatttgaa aagcactcca ggtacaggta ccactatgat gctgactact cccgctggga
4321 ttccacacaa cagcgggcag tgctggaagc ggcacttgaa atcatggtga gattttctgc
4381 tgagccacag ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt
4441 gggcgatttc aaaattgtta tcaatgaagg cctaccatct ggcgtgcctt gcacttcaca
4501 atggaattct attgcccact ggttactcac cctgtgtgcc ctgtctgaag taacaggact
4561 aggccctgac atcatacaag ccaactccat gtactctttc tatggtgatg atgagattgt
4621 gagcacagac ataaaattag atccagagaa attgactgca aaactcaaag aatatggcct
4681 taagcccacc cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg
4741 gttgactttc ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga
4801 ccaaaactcc atcctcaggc agctgtactg gacaagggga cccaaccatg aagaccccag
4861 tgagactatg ataccacacg cacagagacc tgtgcaactc atggcactgc taggagagtc
4921 ctccctacat ggaccctcat tttacagcaa ggttagcaag ctggtcatat ctgaacttaa
4981 agagggagga atggattttt atgtgcccag acaagagtca atgttcaggt ggatgaggtt
5041 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
5101 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5161 ataacgagac ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg
5221 gccaaaacaa tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5281 agttcacagt gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc
5341 ctgatctgaa cccttatttg gctcatttat caaggatgta caatgggtac gctggtggag
5401 ttgaagtcca ggttctcctg gcagggaacg cgttcactgc cgggaagatc ctcttcgccg
5461 ctgtcccgcc aaatttccca gtggaattct taagcccagc ccagattaca atgctcccac
5521 atataatagt agatgttagg actcttgaac caattatgat cccattacct gatgttagga
5581 acacattctt ccactataac aaccagccca acagccgcat gagattagtg gctatgctct
5641 atacccccct tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt
5701 tgactagacc tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta
5761 agactaagcc cttttcctta cccattttaa ccctttctga gctcacaaat tcgaggttcc
5821 cggttcccat tgattcgctt ttcaccgccc agaataatgt gttgcaggtg cagtgtcaaa
5881 atggcaggtg cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca
5941 tctgtgcgtt cagaggacgg gtgacagcag aaactgacaa tcctgataag tggcacatgc
6001 aactgcaaaa cctcaatggc acaacgtatg acccaactga tgatgtgcca gccccactgg
6061 gtacacctga cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg
6121 atgcgcccgg ctcaaccagg gctcatgagg cggtaatttc aacctacagc cccagatttg
6181 tccccaaatt aggctctgtc aattttaaaa gtaatgacga tgatttccaa ttacagccaa
6241 caagattcac accagtgggc atcaatgatg atggcgacca cccgttcaga caatgggaac
6301 tgccagacta ttcaggggtg cttaccttga atatgaacct tgcccccccg gttgctccaa
6361 atttccctgg tgaacaatta ttattcttca gatcttctgt gccatgttca ggaggttaca
6421 accaaggtat tatagattgt cttatccccc aagaatggat ccaacacttc taccaggaat
6481 cagcaccctc tcagtcagac gtggccctga tcaggtacgt caaccccgac acgggtcgca
6541 cactgtttga ggcaaaactg cacagatctg gctatatcac tgtggctcac tctggagact
6601 atcctcttgt tgttccggct aatggatact ttagatttga ctcttgggta aatcagttct
6661 actcactcgc cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc
6721 tttcattgca ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc
6781 aggggcaaac gccatcagcc aaaagataga ctttgaaaac aacaaacaac tccagtctgc
6841 ttcctttcaa catgacaaag agatgctcca agcgcaggta aatgcaacca agcagctgca
6901 atctgagatg atagccctaa aacaggggat tttggccgca ggcggctttt cccccactga
6961 tgcagcgagg ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg
7021 atattgggct cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc
7081 tgtgcacatg cccagcccga gtgctccaca atcaaaaccc gcaaagtcca gatctctagg
7141 ttcttcctct tcttctagta gtgtctatag tatgtctacc caatcaactt ctctaacatc
7201 tggctcttct agtaatgctt cttctgcttc tacaaaattg acaaatttaa gctctggctc
7261 ctctcaaaac aggacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag
7321 tggcgcactc aatatctcac atgtcacgcc accttcaagt agggcctcca gttctgggac
7381 ggtctcaacc gtgcccaagg aagttttgga ctcctggaca tctgcattca acacacgcag
7441 acagccgctc ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat
7501 aattggctat aatatgattt ctttaaaatt taaatttggc taatttgcat ctttt
//