Typing tool
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Typing tool
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Complete norovirus genomes
| PV784270 | GII.17 | |
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| GII.P17 |
ORF1: 1..5108
ORF2: 5089..6705
ORF3: 6705..7444
LOCUS PV784270 7444 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate Hu/GII.17/112/DE/2021 nonstructural
polyprotein (ORF1) gene, partial cds; VP1 (ORF2) gene, complete
cds; and VP2 (ORF3) gene, partial cds.
ACCESSION PV784270
VERSION PV784270.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7444)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7444)
AUTHORS Jacobsen,S., Altmann,B. and Niendorf,S.
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2025) Infectious diseases, Robert Koch-Institute,
Seestr. 10, Berlin 13353, Germany
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) HIVE-hexagon aligner v.
2.1; High-performance Integrated Virtual
Environment (HIVE) HIVE-heptagon profiler
v. 2.1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7444
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.17/112/DE/2021"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Germany"
/collection_date="21-Dec-2021"
/note="genotype: GII.17"
gene <1..5108
/gene="ORF1"
CDS <1..5108
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XVJ37646.1"
/translation="KMASNDASVAVAGKNNNNDKEKSSSNSLFSNMTVTFKKALGARS
EQPPPGETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQ
PDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAA
ISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVI
GKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKL
SSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAR
ELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELAD
TCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDI
EKAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIA
RASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVK
TLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHH
LRSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKG
GCPKPRDEDGLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREER
NGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLG
LVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWV
SPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAP
EGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTP
GDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPI
LGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFT
EPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKND
YWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGS
DLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSR
WDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVP
CTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAK
LKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLFWTR
GPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPR
QESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..998
/gene="ORF1"
/product="p48"
mat_peptide 999..2096
/gene="ORF1"
/product="NTPase"
mat_peptide 2097..2633
/gene="ORF1"
/product="p22"
mat_peptide 2634..3032
/gene="ORF1"
/product="VPg"
mat_peptide 3033..3575
/gene="ORF1"
/product="Pro"
mat_peptide 3576..5105
/gene="ORF1"
/product="RdRp"
gene 5089..6705
/gene="ORF2"
CDS 5089..6705
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XVJ37647.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRINFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMVPLPD
VRNTFFHYNNQPSSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPKFVPKLGSVNFKSYDDDFQLQPTRFTPVGIND
DGNHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6705..>7444
/gene="ORF3"
CDS 6705..>7444
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XVJ37648.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENSKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPNPSAPQSKPVKPRSLGSSSSSSSVYSMSTQST
SLTSGSFNNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPT"
ORIGIN
1 tgaagatggc gtctaacgac gcttccgtcg ccgttgctgg caaaaacaac aacaacgaca
61 aggaaaaatc ttcaagtaac agcttgtttt ctaacatgac tgtcactttt aagaaagccc
121 tcggggcgcg gtctgaacag ccgcccccgg gagaaacaaa acaaacacaa agaccaccaa
181 ggccaccgac accggaattg gtgaagaaga tacccccacc cccccccaat ggcgaggatg
241 aaccaaagat agcgtataag gtgggagaag gtgtgtctgg gctgcccgac ttaacaaccg
301 tggcacaacc tgacgcacag aacacagcct atagtgtccc cccacttagc cagagagagg
361 tcggcgaagc taaagaaccg ttgcctggct ccattctgga aatgtgggat ggtgagatct
421 accactatgg gctgtatgtt gagcgggggc atgtactggg agtgcacaaa ccacctgccg
481 caataagcct tgccaaaatt gagttaacac cactgtctct ctactggaga gtggtttaca
541 ctccccagta tttgatagct ccagagaccc ttaagaattt aaatggagag gctttcccat
601 acacggcctt tgacaacaac tgttatgcct tctgttgttg ggttctagac ctcaacgact
661 cctggcttag cagaagaatg atccaaagaa caactggatt cttcagaccg tatcaggact
721 ggaacagaaa acccttgcca accatggatg aaccaaaaat caagaaggcc gcgaatgctg
781 ttctgtgtgc tctctcctca ctcttcacta ggcccatcaa agatgttatt ggaaagctca
841 aaccactgaa cattatgaac atactggcaa cttgtgattg gacttttgcg ggcatagtgg
901 aatccatgat ccttcttgct gagctctttg gggtgttctg gacgccccca gatgtgtctg
961 caatgattgc tcccttactc ggtgactacg agatgcaagg ccccgaagac ctggccgtgg
1021 aactcgtgcc cgtggtaatg ggaggaatag gtttggtgtt gggattcacc aaggaaaaga
1081 tcggcaagat gctttcatca gctgcgacca cactcagggc ctgtaaggat ctaggatctt
1141 atgggttgga gatactcaaa ctggtcatga agtggttctt ccccaagaag gaggaggcca
1201 acgagttagc catggtgagg gccattgagg atgcggttct ggatttggag gcaatagaaa
1261 acaaccacat gaccactctc cttaaggaca aagacagcct ggccacatac atgaggactc
1321 ttgacttgga agaagaaaaa gcaaggaaac tgtcatccaa atcggcgtca cctgacatcg
1381 tgggcacagt aaacgcatta ttggcaagga tagcagccgc caggtcactg gtccacaagg
1441 ctaaggagga gctctcgagc agacagaggc ctgttgttgt aatgatatca ggtaggccag
1501 gtataggaaa gacccatctg gccagagagc tagccaagaa ggttgcgtct acactgtcag
1561 gcgaccaaag gattggactg atacctagaa atggcgtcga ccattgggac gcctacaaag
1621 gagagcgagt ggttctgtgg gatgactatg gcatgagcaa ccctatacag gacgcactgc
1681 ggctccaaga attggctgac acctgccctc tgaccctaaa ttgtgacagg attgaaaaca
1741 aaggaaaagt gttcgacagt gatgccataa tcataacaac caaccttgca aacccagcac
1801 cactggatta tgtcaacttt gaggcttgtt ctagacgcat agacttcttg gtgtatgcag
1861 acgcacctga catcgagaag gctaagcgtg acttccctgg ccaaccagat atgtggaaag
1921 accattacag atcagacttc tcacacatta aacttcagct ggcaccacag ggaggctttg
1981 ataagaatgg caacacccca catggcaaag gtgtggttaa gtctctgacg attggttctc
2041 tgatcgccag ggcttctggc ttgctccatg agagaatgga tgaattcgag ctccaaggct
2101 ctgacttgcc aaccttcaat ttcgaccgta acaaagtcgc cgcctttaga caattggcag
2161 ctgaaaacaa atatggtctt atggacacac tgagggtcgg caaccaactg aaaagtgtca
2221 aaaccctgga tgagctgaag caggctataa agaacatcac catcaagaag tgccagatag
2281 tgtacaatgg atgcacctac accatggaat ctgatggaag gaacaaggtt gtggttgaaa
2341 aggttcaaaa tgcaacagtc caaaccaaca atgaacttgc aggagcactc caccacctga
2401 gatctgcaag gataaggtat tatgtcaaat gtttccaaga agctatttac tctctactcc
2461 aaattgctgg tgcagccttc gtcaccacac gcatcgtgag gcgcatgaac atctcaaacc
2521 tctggtcgaa gccacccgtc gaagagggtg atgagcctga agacaagggg gggtgcccca
2581 agcccaggga tgaagatggc ctcactattg actctaaaga cattaaagca gaagggaaga
2641 agggcaagaa caaatctggc cggggcaaga aacacacagc tttctcatcc aagggtctca
2701 gtgatgaaga gtacgatgag tacaagagaa tcagggagga gaggaatggc aaatactcaa
2761 tagaagaata cctccaggat agggatagat actatgaaga gcttgccatt gctaaggcca
2821 ctgaggaaga cttctgtgaa gaggaggaaa ttaaaattcg ccagagaatc ttccggccca
2881 ccaggaagca acggagagag gaaagagcca cgcttgggct tgtcacagga tcggaaatca
2941 gaaagaggaa cccagatgac tttaagccaa aaggaaaatt gtgggctgat gacaacagaa
3001 gtgtggacta caatgagagg atagattttg aggctccccc gagtgtttgg tctcggatag
3061 tcaactttgg tacaggatgg ggattctggg tctccccaag tcttttcata acttcaacac
3121 atgtcatacc aaaaggaatc actgaggcct ttggagttcc cattaaccaa attcaaattc
3181 acaaatctgg agagttttgc cgcttgcggt ttccaaaacc aatcaggcca gacgtgagtg
3241 gaatgatctt ggaagagggt gcccctgaag gcactgttgt gtccattctc atcaagagga
3301 caacagggga actgatgcct ctcgcagtta gaatgggaac tcatgccaca atgaaaatcc
3361 aaggtagaac ggtgggtggt caaatgggca tgcttctcac tggctcaaac gctaaaagca
3421 tggacctagg cacaacacca ggtgactgcg ggtgcccata catatacaaa aggggcaatg
3481 acttcgtggt cattggggtg cacactgcag cagcccgtgg aggcaacacg gtcatatgtg
3541 ccacacaggg aagtgagggc gaagccaccc tcgaaggagg tgacaacaag ggcacctatt
3601 gtggagcccc catcttggga cctggtaacg caccaaaatt gagcacaaaa acaaaattct
3661 ggagatcttc taacgcgccg ctccctccag gcacctatga accagcatac cttggtggaa
3721 aagacccgcg tgtgaaggga ggcccatctc tacaacaggt tatgagagac caacttaaac
3781 cttttacaga gcccagaggg aagccaccaa aaccaagtgt cctagaatca gcaaagaaga
3841 ccatcattaa tgttctggaa caaaccattg acccccctga aaagtggtca tatgcccaag
3901 cttgtgcatc cctcgacaag acaacctcca gtggataccc gcatcacgtc cggaagaatg
3961 actattggag tggtgaatcc ttcacgggga aacttgcaga ccaggcctca aaagcaaacc
4021 ttatgtatga ggaaggcaag cacatgcaac cagtttacac cgcagcactc aaagacgagc
4081 tcgtgaaaac tgataaaatt tatggcaaga tcaagaaaag actcctgtgg ggctctgacc
4141 tatccaccat gattcgatgc gccagggcat ttggtggcct catggatgag ctcaaagcaa
4201 attgtatcac actccctatc agagttggta tgaacatgaa tgaagatggt cccataatat
4261 ttgagaagca ctccaggtac aggtaccact atgatgctga ttactcccgc tgggattcca
4321 cacaacagcg ggcagtgctg gaagcggcac ttgaaatcat ggtgagattt tctgctgagc
4381 cacagttggc acaaatagtg gcagaggacc tgctatcacc aagtgtggtt gacgtgggcg
4441 atttcaaaat tactatcaat gaaggcctac catctggcgt gccttgcact tcacaatgga
4501 attctattgc ccactggtta ctcaccctgt gtgccctgtc tgaagtaaca ggactaggcc
4561 ctgacatcat acaagccaac tccatgtact ctttctatgg tgatgatgag attgtgagca
4621 cagacataaa attagaccca gagaaattga ctgcaaaact caaagaatat ggtcttaaac
4681 ccacccggcc tgacaagact gaggggccac tggtaattag tgaggacctg aatgggttga
4741 ctttcctccg ccgaacagtc acccgcgatc cagcgggttg gtttggaaag ttggaccaaa
4801 actccatcct caggcagctg ttctggacaa ggggacccaa ccatgaagac cccagtgaga
4861 ctatgatacc acacgcacag agacctgtgc agctcatggc actgctagga gaatcctccc
4921 tacatggacc ctcattttac agcaaggtta gcaagctggt catatctgaa cttaaagagg
4981 gaggaatgga tttttatgtg cccagacaag agtcaatgtt caggtggatg aggttctcag
5041 atctaagcac atgggagggc gatcgcaatc tggctcccag ttttgtgaat gaagatggcg
5101 tcgaatgacg ccgctccatc taatgatggt gctgctggtc tcgtaccaga gggcaataac
5161 gagacccttc ccctagaacc agttgcgggc gcagctatag ccgcacccgt cactggccaa
5221 aacaatataa ttgacccctg gattagaata aattttgtgc aagcaccaaa tggagagttc
5281 acagtgtcac ccagaaactc tcctggagaa attttactaa acctagagtt gggccctgat
5341 ttgaaccctt atttggctca tttgtcaagg atgtacaatg ggtatgctgg tggagttgaa
5401 gtccaggttc tcctggcagg gaacgcgttc actgccggga agatcctctt cgccgctgtc
5461 ccgccaaatt tcccagtgga attcttaagc ccagcccaga ttacaatgct cccacatata
5521 atagtagatg ttaggactct tgaaccaatt atggtcccat tacctgatgt taggaacaca
5581 ttcttccact ataataacca gcccagcagc cgcatgagat tagtggctat gctctacacc
5641 ccccttagat ctaatggctc aggtgatgat gttttcactg tttcttgtag ggttttgact
5701 aggcctactc ctgattttga gttcacttat ctagtgccac cctctgttga atctaagact
5761 aagccctttt ccttacccat tctaaccctt tctgagctca caaattcgag gttcccggtc
5821 cccattgatt cgcttttcac cgcccagaac aatgtgttgc aggtgcagtg tcaaaatggc
5881 aggtgcacac ttgacggtga gctacaaggc acaacccagt tgctcccatc tggcatctgt
5941 gcgttcagag gacgggtgac agcagaaact gacaatcctg acaagtggca catgcaactg
6001 caaaacctca atggcacaac atatgaccca actgatgatg tgccagcccc actgggtaca
6061 cctgacttca agggcgtcgt gtttgggatg gcaagccaaa gaaatgtggg taacgatgcg
6121 cccggctcaa ccagggctca tgaggcggtg atttcaacct acagccccaa atttgttccc
6181 aaattaggct ctgtcaattt taaaagttat gacgatgatt tccaattgca gccaacaaga
6241 ttcacaccag tgggcattaa tgatgatggc aaccacccgt tcagacaatg ggaactgcca
6301 gactattcag gggtgcttac cttgaatatg aaccttgccc ccccggttgc tccaaatttc
6361 cctggtgaac aattattatt cttcagatct tccgtgccat gttcaggagg ttacaaccaa
6421 ggtattatag attgtcttat cccccaagaa tggatccaac acttctacca ggaatcagca
6481 ccttctcagt cagacgtggc cctgatcagg tacgtcaacc ccgacacggg tcgcacgctg
6541 tttgaggcaa aattgcacag atctggctat atcactgtgg ctcactctgg agactatcct
6601 cttgttgttc cggctaatgg atactttaga tttgactctt gggtaaatca gttttactca
6661 ctcgccccaa tgggaactgg gaatgggcga aggagggctc agtaatggct ggagctttca
6721 ttgcaggatt ggcgggtgac atgctcacgt catccgtggg ctccctggtg aacgcagggg
6781 caaacgccat cagtcaaaag atagactttg aaaacagcaa acaactccag tctgcttcct
6841 ttcaacatga taaagagatg ctccaagcgc aggtgaatgc aaccaagcag ctgcaatctg
6901 agatgatagc cctaaaacag ggggttttgg ccgcaggcgg cttttccccc actgatgcag
6961 cgaggggggc cattggtgca cccatgacaa aggtgcttga ctggtctggc actcgatact
7021 gggctcccaa ttccacaaag acaactggtt attcggggca attcacctct tcacctgtgc
7081 acatgcccaa cccgagtgct ccacaatcaa aacccgtaaa gcccaggtct ctaggttctt
7141 cttcttcttc tagtagtgtt tatagtatgt ctacccaatc aacttctcta acatctggct
7201 cttttaataa tgcttcttct gcttctacaa aattgacaaa tttaagctcc ggctcctctc
7261 aaaacagaac agcagagtgg gtgaaccaac agagaagtct cagccctttc atgagtggcg
7321 cactcaacat ctcacatgtc acgccacctt caagtagggc ctccagttct gggacggtct
7381 caaccgtgcc caaggaagtt ttggactcct ggacatctgc attcaacaca cgcagacagc
7441 cgac
//