Typing tool
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Typing tool
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Complete norovirus genomes
| PV765509 | GII.17 | |
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| GII.P17 |
ORF1: 1..5105
ORF2: 5086..6702
ORF3: 6702..7481
LOCUS PV765509 7516 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate Hu/SP/2023/GII.17P17/CNM970 nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV765509
VERSION PV765509.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7516)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7516)
AUTHORS Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-2025) ENTEROVIRUS AND VIRAL GASTROENTERITIS,
INSTITUTO DE SALUD CARLOS III, Ctra. Majadahonda-Pozuelo, Km 2,
MAJADAHONDA, MADRID 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7516
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/SP/2023/GII.17P17/CNM970"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Madrid Region"
/collection_date="Mar-2023"
/note="genotype: GII.17[P17]"
gene <1..5105
/gene="ORF1"
CDS <1..5105
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUY71647.1"
/translation="MASNDASVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARSK
QPPPGETKQTQRPPRPPTPELVKKIPPPTPNGEDEPKIAYKVGEGVSGLPDLTTVAQP
DAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLND
SWLSRRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIG
KLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYTRTLDLEEEKARKLS
SKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELTGALHHL
RSARIRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGG
CPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGL
VTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGSDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2630
/gene="ORF1"
/product="p22"
mat_peptide 2631..3029
/gene="ORF1"
/product="VPg"
mat_peptide 3030..3572
/gene="ORF1"
/product="Pro"
mat_peptide 3573..5102
/gene="ORF1"
/product="RdRp"
gene 5086..6702
/gene="ORF2"
CDS 5086..6702
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUY71648.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDNDFQLQPTRFTPVGIND
DGDHPYRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6702..7481
/gene="ORF3"
CDS 6702..7481
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUY71649.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGILAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKSAKSRSLGSSSSSSSVYSMSTQST
SLTSGSSSNVSSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 agatggcgtc taacgacgct tccgtcgccg ttgctggcaa aaacaacaac aacgacaagg
61 aaaaatcttc aagtgacagc ttgttttcta acatgactgt tacttttaag aaagccctcg
121 gggcgcggtc taaacagccg cccccgggag aaacaaaaca aacacaaaga ccaccaaggc
181 caccgacacc ggaattggtg aagaagatac ccccacccac ccccaatggc gaggatgaac
241 caaagatagc gtataaggtg ggagaaggtg tgtctgggct gcccgacttg acaaccgtgg
301 cacaacctga cgcacagaac acagcctaca gtgtcccccc acttagccag agagaggtcg
361 gcgaagctaa agaaccgttg cctggctcca ttctggaaat gtgggatggt gagatctacc
421 actatgggct gtatgttgag cgggggcatg tactgggagt gcacaaacca cctgccgcaa
481 taagccttgc caaaattgaa ttaacaccgc tgtctctcta ctggagagtg gtttacactc
541 cccagtattt gatagctcca gagaccctta agaatttaaa tggagaggct ttcccataca
601 cggcctttga caacaactgt tatgccttct gttgttgggt tttagacctc aacgactcct
661 ggcttagcag aagaatgatc caaagaacaa ctggattctt tagaccgtat caggactgga
721 acagaaaacc cttgccaacc atggatgaac caaaaatcaa gaaggccgcg aatgctgttc
781 tgtgtgctct ctcctcactc ttcactaggc ccatcaaaga tgtcattgga aagctcaaac
841 cactgaacat catgaatata ctggcaactt gtgattggac ttttgcgggc atagtggaat
901 ccatgatcct tcttgctgag ctctttgggg tgttctggac gcccccagat gtgtctgcaa
961 tgattgctcc cttactcggt gactacgaga tgcaaggccc cgaagacctg gccgtagaac
1021 ttgtgcccgt ggtaatggga ggaataggtt tggtgttagg attcaccaag gaaaagatcg
1081 gcaagatgct ttcatcagct gcgaccacac tcagggcctg taaggatcta ggatcttatg
1141 ggttggagat actcaaactg gtcatgaagt ggttcttccc caagaaggag gaggccaacg
1201 agttagccat ggtgagggcc attgaggatg cagttctgga tttggaggca atagaaaaca
1261 accacatgac cactctcctt aaggacaaag acagcctggc cacgtacacg aggactcttg
1321 acttggaaga agaaaaagcg aggaaactgt catccaaatc ggcatcacct gacatcgtgg
1381 gcacagtaaa tgcactattg gcaaggatag cagccgccag gtcactggtc cacaaggcta
1441 aggaggagct ctcgagcaga cagaggcctg ttgttgtaat gatatcaggt aggccaggta
1501 taggaaagac ccatttggcc agagagctag ccaagaaggt tgcgtcaaca ctgtcaggcg
1561 accaaaggat tggactgata cctagaaatg gcgtcgacca ttgggacgcc tacaaaggag
1621 agcgggtggt tctgtgggat gactatggca tgagcaaccc tatacaggac gcactgaggc
1681 tccaagaatt ggctgacacc tgtcctctga ccctgaattg tgacaggatt gaaaacaaag
1741 gaaaagtgtt cgacagtgac gccataatta taacaaccaa cctcgcaaac ccagcaccac
1801 tggattacgt caactttgag gcttgttcta gacgcataga cttcttggtg tatgcagacg
1861 cacctgacat cgagaaggct aagcgtgact tccctggcca accagatatg tggaaagacc
1921 attacagatc agacttctca cacattaaac tccagctggc accacaggga ggctttgata
1981 agaatggcaa caccccacat ggcaaaggtg tggttaagtc tctgacgatt ggttctctga
2041 tcgccagggc ttctggcttg ctccatgaga gaatggatga atttgagctc caaggctctg
2101 acctaccaac cttcaatttc gaccgtaaca aagtcgccgc cttcagacaa ttggcagctg
2161 aaaacaaata tggtcttatg gacacactga gggtcggcaa ccaactgaaa agtgtcaaaa
2221 ccctggatga gctgaagcag gctataaaga acatcaccat caagaagtgc cagatagtgt
2281 acaatggatg cacctacacc atggaatctg atgggaggaa caaggttgtg gttgaaaagg
2341 ttcaaaatgc aacagtccaa accaacaatg aacttacagg agcactccac cacctaagat
2401 ctgcaaggat aaggtattat gttaaatgtt tccaagaagc tatttactct ctactccaaa
2461 ttgctggtgc agccttcgtc accacacgca tcgtgaggcg catgaacatc tcaaacctct
2521 ggtcgaaacc acccgtcgaa gagggtgatg agcctgaaga caaagggggg tgccccaagc
2581 ccagggatga agatgacctc actattgact ctaaagacat taaagcagaa gggaagaagg
2641 gcaagaacaa atctggccgg ggcaagaagc acacagcttt ctcatccaag ggcctcagtg
2701 atgaagagta cgatgagtac aagagaatca gggaggagag gaatggcaaa tactcaattg
2761 aagaatacct ccaggacagg gatagatact atgaagagct tgccattgct aaggccactg
2821 aggaagactt ctgtgaagag gaggaaatca aaattcgcca gagaatcttc cggcccacca
2881 ggaagcaacg gagagaggaa agagccacgc ttgggcttgt cacaggatcg gaaatcagaa
2941 agaggaaccc agatgatttt aagccaaaag gaaaattgtg ggctgatgac aacagaagtg
3001 tggactacaa cgagaggata gattttgagg ctcccccgag tgtttggtct aggatagtca
3061 actttggtac aggatgggga ttctgggtct ccccaagtct ctttataact tcaacacatg
3121 tcataccaaa aggaatcact gaggcctttg gagttcccat taaccaaatt caaattcaca
3181 aatctggaga gttttgccgc ttgcggtttc caaaaccaat caggccagac gtgagtggaa
3241 tgatcttgga agagggtgcc cctgaaggca ctgttgtgtc cattctcatc aagaggacaa
3301 caggggaact gatgcctctt gcagttagga tggggactca tgccacaatg aaaatccaag
3361 gtagaacggt gggtggtcaa atgggcatgc ttctcactgg ctcaaacgct aaaagcatgg
3421 acctaggcac aacaccaggt gactgtgggt gcccatacat atacaaaagg ggcagtgact
3481 tcgtggtcat tggggtgcac actgcagcag cccgtggagg caacacggtc atatgtgcca
3541 cacagggaag tgaaggcgaa gccaccctcg aaggaggtga caacaagggc acctattgtg
3601 gagcccctat cttgggaccc ggcaacgcac caaagttaag cacaaaaaca aaattttgga
3661 gatcttccaa cgcgccgctt cctccaggta cctatgaacc agcatacctt ggtggaaaag
3721 acccgcgtgt gaagggaggc ccatctctac aacaggttat gagagaccaa cttaaacctt
3781 ttacagagcc aagaggaaag ccaccaaaac caagtgtcct agaatcagca aagaagacca
3841 tcattaatgt tctggagcaa accattgacc cccctgaaaa gtggtcatat gcccaagctt
3901 gtgcatccct cgacaagaca acctccagtg gatacccgca tcacgtccgg aagaatgact
3961 attggagtgg tgaatccttc acggggaaac ttgcagacca ggcctcaaaa gcaaacctta
4021 tgtatgagga aggcaagcac atgcaaccag tttacaccgc agcactcaaa gacgagctcg
4081 tgaaaactga caaaatttat ggcaagatca agaaaagact cctgtggggc tctgacctat
4141 ctaccatgat tcgatgcgcc agggcatttg gtggcctcat ggatgagctc aaagcaaatt
4201 gtatcacact ccctatcaga gttggtatga acatgaatga agatggcccc ataatatttg
4261 aaaagcactc caggtacagg taccactatg atgctgatta ctcccgctgg gattccacac
4321 aacagcgggc agtgctggaa gcggcacttg aaatcatggt gagattttct gctgagccac
4381 agttggcaca aatagtggca gaggacctgc tatcaccaag tgtggttgat gtgggcgatt
4441 tcaagattgc tatcaatgaa ggcctaccat ccggcgtgcc ttgcacttca caatggaatt
4501 ctattgccca ctggttactc accctgtgtg ccctgtctga agtaacagga ctaggccctg
4561 acatcataca agccaactcc atgtactctt tctatggtga tgatgagatt gtgagcacag
4621 acataaaatt agacccagag aaattgactg caaaactcaa agaatatggc cttaaaccca
4681 cccggcctga caagactgag gggccactgg taattagtga ggacctgaat gggttgactt
4741 tcctccgccg aacagtcacc cgcgatccag cgggttggtt tggaaagttg gaccaaaact
4801 ccatcctcag gcagctgtac tggacaagag ggcccaacca tgaagacccc agtgagacta
4861 tgataccaca cgcacagaga cctgtgcagc tcatggcact gctaggagag tcctccctac
4921 atggaccctc attttacagc aaggttagca agctggtcat atctgaactt aaagagggag
4981 gaatggattt ttatgtgccc agacaagagt caatgttcag gtggatgagg ttctcagatc
5041 taagcacatg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg
5101 aatgacgccg ctccatctaa tgatggtgct gctggtctcg taccagaggg caataacgag
5161 acccttcccc tagaaccagt tgcgggcgca gctatagccg cacccgtcac tggccaaaac
5221 aatataattg acccctggat tagaacaaat tttgtgcaag caccaaatgg agagttcaca
5281 gtgtcaccca gaaactctcc tggagaaatt ttattaaacc tagagttggg ccctgatttg
5341 aacccttatt tggctcattt atcaaggatg tacaatgggt acgctggtgg agttgaagtc
5401 caggttctcc tggcagggaa cgcgttcact gccgggaaga tcctcttcgc cgctgtcccg
5461 ccaaatttcc cagttgaatt cttaagccca gcccagatta caatgctccc acatataata
5521 gtagatgtta ggactcttga accaattatg atcccattac ctgatgttag gaacacattc
5581 ttccactata acaaccagcc caacagccgc atgagattag tggctatgct ctataccccc
5641 cttagatcta atggctcagg tgatgatgtt ttcactgttt cttgcagggt tttgactaga
5701 cctactcctg attttgagtt cacttatcta gtgccaccct ctgttgaatc taagactaag
5761 cccttttcct tacccatttt aaccctttct gagctcacaa attcgaggtt cccggtcccc
5821 attgattcgc ttttcaccgc ccagaataat gtgttgcagg tgcagtgtca aaacggcagg
5881 tgcacacttg acggtgagct acaaggcaca acccagttgc tcccatctgg catctgtgcg
5941 ttcagaggac gggtgacagc agaaactgac aatcctgata agtggcacat gcaactgcaa
6001 aacctcaatg gcacaacgta tgacccaact gatgatgtgc cagccccact gggtacacct
6061 gacttcaagg gcgtcgtgtt tgggatggca agccaaagaa atgtgggtaa tgatgcgccc
6121 ggctcaacca gggctcatga ggcggtgatt tcaacctaca gccccagatt tgttcccaaa
6181 ttaggctctg tcaattttaa aagtaatgac aatgattttc aattgcagcc aacaagattc
6241 acaccagtgg gcatcaatga tgatggcgac cacccgtaca gacaatggga actgccagac
6301 tattcagggg tgcttacctt gaatatgaac cttgcccccc cggttgctcc aaatttccct
6361 ggtgaacaat tattattctt cagatcttcc gtgccatgtt caggaggtta caaccaaggt
6421 attatagatt gtcttatccc ccaagaatgg atccaacact tctaccagga atcagcacct
6481 tctcagtcag acgtggccct gatcaggtac gtcaaccccg acacgggtcg cacactgttt
6541 gaggcaaaat tgcacagatc tggctatatc actgtggctc actctggaga ctatcctctt
6601 gttgttccgg ctaatggata ctttagattt gactcttggg taaatcagtt ttactcactc
6661 gccccaatgg gaactgggaa tgggcgaagg agggctcagt aatggctgga gcttttattg
6721 caggattggc gggtgacatg ctcacgtcat ccgtgggctc cctggtgaac gcaggggcaa
6781 acgccatcag ccaaaagata gactttgaaa acaacaaaca actccagtct gcttcctttc
6841 aacatgataa agagatgctc caagcgcagg tgaatgcaac caagcagctg caatctgaga
6901 tgatagccct aaaacagggg attttggccg caggcggctt ttcccccact gatgcagcga
6961 ggggggccat cggtgcaccc atgacaaagg tgcttgactg gtctggcact cgatattggg
7021 ctcccaattc cacaaagaca actggctatt cggggcaatt cacctcttca cctgtgcaca
7081 tgcccagccc gagtgctcca caatcaaaat ccgcaaagtc cagatctcta ggttcttctt
7141 cctcttctag tagtgtttat agtatgtcta cccaatcaac ttctctaact tctggctctt
7201 ctagtaatgt ttcttctgct tctacaaaat tgacaaattt aagctctggc tcctctcaaa
7261 acaggacagc agagtgggtg aaccaacaga gaagtctcag ccctttcatg agtggcgcac
7321 tcaatatctc acatgtcacg ccaccttcaa gtagggcctc tagttctggg acggtctcaa
7381 ccgtgcccaa ggaagttttg gactcctgga catctgcatt caacacacgc agacagccgc
7441 tcttcgcaca cctcagagtg aggggggagt cacgtgttta gtgaaaagaa ataattggct
7501 ataatgtgat ttcttt
//