Typing tool
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Typing tool
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Complete norovirus genomes
| PV765507 | GII.17 | |
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| GII.P17 |
ORF1: 1..5105
ORF2: 5086..6708
ORF3: 6708..7487
LOCUS PV765507 7522 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate Hu/SP/2022/GII.17P17/CNM118 nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV765507
VERSION PV765507.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7522)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7522)
AUTHORS Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (10-JUN-2025) ENTEROVIRUS AND VIRAL GASTROENTERITIS,
INSTITUTO DE SALUD CARLOS III, Ctra. Majadahonda-Pozuelo, Km 2,
MAJADAHONDA, MADRID 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7522
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/SP/2022/GII.17P17/CNM118"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Murcia Region"
/collection_date="Mar-2022"
/note="genotype: GII.17[P17]"
gene <1..5105
/gene="ORF1"
CDS <1..5105
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUY71641.1"
/translation="MASNDASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSK
QPPPGETKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQP
DAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLND
SWLSRRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIG
KLRPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLS
TKSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHL
RSARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGG
CPKPRDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGL
VTGSEIRKRNPDDFKPKGRLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKGMDLGTTPG
DCGCPYIYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2630
/gene="ORF1"
/product="p22"
mat_peptide 2631..3029
/gene="ORF1"
/product="VPg"
mat_peptide 3030..3572
/gene="ORF1"
/product="Pro"
mat_peptide 3573..5102
/gene="ORF1"
/product="RdRp"
gene 5086..6708
/gene="ORF2"
CDS 5086..6708
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUY71642.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISNNDDFQFQPTKFTPVGVN
DDDDDHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6708..7487
/gene="ORF3"
CDS 6708..7487
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUY71643.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 agatggcgtc taacgacgct tccgctgccg ttgctggcaa aaacaacaac aacgacaagg
61 aaaaatcttc aagtgacagc ttgtttgcta acatgtctgt cacttttaag aaagccctcg
121 gggcgcggtc taaacaaccg cccccgggag aaacaaaaca aatacaaaaa ccaccaaggc
181 caccgacacc ggaattggtg aagagaatac ctccaccccc acccaatggc gaggatgaac
241 cagggatagt gtacaaggtg ggagagggcg tgtctgggct gcccgaccta acaactgtgg
301 tacaacctga cgcacaaaac acagcttata gtgttccccc acttagccag agagaagtcg
361 gcgaagctaa agaaccgctg cctggctcca tcctggaaat gtgggatggt gagatctacc
421 actatgggct gtatgttgag cgggggcatg tgctcggagt acacaaacca cctgctgcaa
481 taagccttgc caaaattgaa ataacaccgc tgtctctcta ctggagagtg gtctacactc
541 cccagtattt gatagatcca ggaactctta agaacttgag tggagagact ttcccataca
601 cggcctttga caacaactgt tatgccttct gttgttgggt cctagacctc aacgactcct
661 ggcttagcag gagaatgatc caaagaacaa ctggattctt caaaccttat caggattgga
721 acagaaaacc cttaccaacc atggatgaac cgaaaatcaa gaaggccgcg aatgctgtcc
781 tatgcgctct ctcctcactc ttcactagac ccattaagga catcattgga aagcttagac
841 cactgaacat tcttaatata ctggcaacct gcgattggac ttttgcaggc atagtggaat
901 ccttgatcct tcttgctgaa ctctttgggg tgttctggac acccccagat gtgtctgcga
961 tgattgctcc cttactcggt gactacgaga tgcaaggccc cgaagacctg gccgtggaac
1021 ttgtacccgt ggtgatggga ggaataggtt tggtgttagg attcaccaaa gaaaagatcg
1081 gcaagatgct ttcatcagct gcgaccacac ttagggcctg caaggatcta ggatcttatg
1141 gattggagat actcaaattg gtcatgaagt ggttcttccc caagaaggag gaggctaacg
1201 aactagccat ggtgagggcc attgaggatg cagtcctgga tttggaggca atagaaaaca
1261 atcacatgac cacccttctc aaggataaag acagcctggc cacatacatg aggactcttg
1321 acttggaaga agagaaagca aggaaactgt caaccaaatc ggcgtcacct gacatcgtgg
1381 gtacaataaa cgcattgttg gctaggatag cagccgccag gtcactggtc cacaaggcta
1441 aggaggagct ctcgagcaga cagagacctg ttgttgtaat gatatcaggc agaccaggta
1501 taggaaagac ccatctggcc agagagctag ccaagaaagt tgcgtcaaca ctgtcaggcg
1561 accaaaggat tggactggta cctaggaatg gcgtcgacca ttgggacgcc tacaagggag
1621 aaagggtggt cctgtgggat gattatggta tgagcaaccc tatacaggac gcactgaggc
1681 tccaagaatt ggctgacacc tgtcctctga ccctaaattg tgataggatt gaaaacaaag
1741 gaaaagtgtt cgacagtgat gccataatta taacaaccaa ccttgcaaac ccagcaccac
1801 tagactatgt caactttgag gcctgctcta gacgcataga cttcttggtg tatgcagatg
1861 cacctgacat tgagaaggct aagcgtgact tccctggcca accagatatg tggaaagacc
1921 atttcagacc agacttctca cacattaaac ttcagctggc accacaggga ggttttgaca
1981 aaaatggcaa caccccacat ggcaaaggtg tggtaaagtc cctgacgatt ggttctctga
2041 tcgccagggc ctccggcttg ctccacgaga gaatggatga attcgagctc caaggctctg
2101 acctgccaac cttcaatttt gaccgcaaca aagtcgccgc cttcagacaa ttagcagctg
2161 aaaacaaata tggtcttatg gacacattga gggtcggcaa ccaactgaaa agtgttaaga
2221 ccctggatga gctgaagcag gccataaaga acatcagtat caagaagtgt cagatagtgt
2281 ataatggatg cacctatacc atggaatctg atgggagggg caaggttgtg gttgaaaagg
2341 tacaaaacgc aacagttcaa accaacaatg aacttgtagg ggcgctccac cacctgagat
2401 ctgcaaggat aagatactat gttaaatgtt tccaagaagc catttactct ctactccaaa
2461 ttgctggtgc agcctttgtc acctcacgca tcgtgaggcg catgaacata tcaaacctct
2521 ggtcgaagcc acccatcgag gagggtgatg agcctgaaga cagaggagga tgccccaagc
2581 ccagggatga agatgacctc actattgact ctagagacat taaagtggaa gggaagaagg
2641 gcaagaacaa gtctggccgg ggcaagaaac acacagcctt ctcttccaag ggcctcagtg
2701 atgaagagta cgatgagtac aagagaatca gagaggagag gaatggcaaa tactcaatag
2761 aggaatacct ccaagatagg gacagatact atgaagagct tgccattgct aaggccactg
2821 aggaggactt ctgtgaggag gaggagatca aaatccgcca gagaatcttc cgacccacca
2881 ggaagcagcg gaaagaggaa agggccacgc ttgggcttgt cacaggatcg gaaatcagaa
2941 agaggaatcc agatgacttt aaaccaaaag gaagattgtg ggctgatgac aacaggagcg
3001 tggattacaa tgagaggata gattttgagg ctcccccgag cgtttggtct aggatagtca
3061 actttggcac aggttgggga ttctgggttt ctccaagtct ctttataact tcaacacacg
3121 tcataccaaa aggaatcact gaggcctttg gagtgcccat aaaccaaatc caaattcaca
3181 aatctggaga attttgccgc ttgcggtttc caaagccaat tagaccagac gtgagtggga
3241 tgatcttgga agagggcgcc cctgaaggca ctgttgtgtc tattctcatc aaaaggacaa
3301 caggggagct gatgcctctt gcagtcagaa tggggactca tgccacaatg aaaatccaag
3361 gtagaacggt gggtggtcag atgggtatgc ttctcactgg ctcaaatgct aaaggcatgg
3421 atctaggcac aacgccaggt gactgcggat gtccatacat atacaaaagg ggcaatgacc
3481 ttgtggtcat tggggtgcac actgcagcag ctcgtggagg caacacggtc atatgtgcca
3541 cacagggaag tgaaggtgaa gccactcttg aaggaggtga caacaagggt acctattgtg
3601 gagcccccat tttgggacct ggcaatgcac caaaattgag cacaaagaca aaattctgga
3661 gatcctctaa cgcaccgctt cccccaggta cttatgaacc agcatacctt ggtgggagag
3721 acccgcgcgt gaaaggaggc ccatctctgc aacaagttat gagagaccaa cttaaacctt
3781 tcacagagcc cagagggaag ccaccaaacc caaatgtctt agagtcagca aagaagacta
3841 tcatcaatgt tctggaacaa accattgacc cccctcaaaa gtggtcatat gcccaagctt
3901 gtgcatccct cgacaagaca acctccagtg gatacccgca ccacgtccgg aagaatgact
3961 attggagtgg tgaatccttc acaggaaaac ttgcagatca ggcttcaaaa gcaaatctca
4021 tgtatgagga aggcaagcac atgcaaccag tttacaccgc agcactcaaa gacgagctcg
4081 tgaaaactga caaaatttat ggtaaaatca agaaaagact cctgtggggt tctgacctct
4141 ccacaatgat tcgatgcgcc agagcatttg gtggtctcat ggatgaattc aaagcaaatt
4201 gcattacact ccctatcaga gttggtatga atatgaatga agatggtccc ataatatttg
4261 agaaacactc caggtacagg taccactatg atgctgatta ctcccgctgg gactccacac
4321 aacagcgggc agtgctggaa gcggcacttg aaatcatggt gaggttttct gctgagccac
4381 agctggcaca aatagtggcc gaggacctgc tgtcaccaag tgtggttgat gtgggcgatt
4441 tcaaaatcgc tatcaatgaa ggcctaccat ctggcgtgcc ttgcacctca caatggaatt
4501 ctattgccca ctggttactc accttgtgtg ccctttctga agtgacagga ttaggtcctg
4561 acatcataca agctaactcc atgtactctt tctatggtga tgatgagatt gtgagcacag
4621 acataaaatt ggacccagag aaattgaccg caaagctcaa agaatatggc cttaaaccca
4681 ctcggcccga caaaactgag gggccgttgg tgattagtga ggacctgaat gggttgactt
4741 tcctccgccg aacagtcacc cgtgatccag caggttggtt tggaaagttg gaccaaaact
4801 ccatcctcag gcagttgtac tggacaagag gacccaacca tgaagacccc agtgagacca
4861 tgataccaca cgcacaaaga cctgtgcagc tcatggcact actaggagaa tcctccctac
4921 atggaccctc attttacagc aaggttagca aattagtcat atctgaactt aaagagggag
4981 gaatggattt ttatgtgccc agacaagagt caatgttcag atggatgagg ttctcagatc
5041 taagcacatg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg
5101 aatgacgccg ctccatctaa tgatggtgct gctggtctcg taccagaggg caacaacgag
5161 acccttcccc tagaaccagt tgcgggcgca gctatagccg cacccgtcac tggccaaaat
5221 aatataattg acccctggat tagaacaaat tttgtgcaag caccaaatgg agagttcaca
5281 gtgtcaccca gaaactctcc tggagaaatt ctattaaatt tagagttggg ccctgatttg
5341 aacccttatt tggctcattt gtcaaggatg tacaatgggt atgctggtgg agtggaagtt
5401 caggttctcc tggcagggaa cgcgttcact gccggaaaga tcctcttcgc cgccgtcccg
5461 ccaaatttcc cagtggaatt cttaagccca gcccagatca caatgctccc acatttaata
5521 gtagatgtta ggactcttga accaattatg atcccactcc ctgatgttag gaatacattc
5581 ttccattata gtaaccagcc taacagccgc atgagattag tggctatgct ctacacccca
5641 ctcagatcta atggctcagg tgatgatgtc tttactgtct cttgcagggt tttgactagg
5701 cctactcctg attttgagtt cacttattta gtgccacctt ctgttgaatc taaaactaag
5761 cctttttcct tacctatttt aaccctttct gagctcacaa attcgaggtt tccagtcccc
5821 atcgattcgc ttttcaccgc ccagaataat gtgttgcagg tgcagtgtca aaatggcagg
5881 tgtacacttg atggtgagtt acaaggcaca acccagttgc tcccaactgg catctgtgca
5941 ttcagaggac gggtgacagc acaaattaac caacgtgaca ggtggcacat gcaactgcaa
6001 aacctcaatg gtacaacata tgacccaact gatgatgtgc cagccccgct gggtacacct
6061 gacttcaagg gcgtcgtgtt tgggatggta agccaaagaa atgtgggtaa tgatgcgcct
6121 ggctcaacca gagcccaaca ggcgtgggtt tcaacctata gcccccaatt tgtccccaaa
6181 ttaggttctg tcaatcttag aattagtaat aatgatgatt tccaattcca gccgacaaaa
6241 ttcacaccag tgggcgtcaa tgatgacgat gatgaccacc cgttcagaca gtgggaacta
6301 ccaaactatt caggggagct taccttgaat atgaatcttg cccccccagt tgctccaaat
6361 tttcctggtg aacaattgtt attcttcagg tctttcgtgc catgctcggg aggttacaac
6421 caaggtatta tagattgtct tatcccccaa gaatggatcc aacacttcta tcaggaatca
6481 gcaccctccc agtcagacgt ggccctaatc aggtatgtca accccgatac gggacgtaca
6541 ctgtttgaag caaaattgca cagatctggt tacattactg tggctcactc tggagactat
6601 cctcttgttg ttccggctaa tggacacttt agatttgatt cttgggtaaa tcagttttac
6661 tcactcgccc caatgggaac tgggaatggg cgaaggaggg ctcagtaatg gctggggctt
6721 tcattgcagg attggcaggc gacatgctca cgtcatctgt gggctccctt gtgaacgcag
6781 gggcaaacgc catcaaccaa aagatagact ttgaaaacaa caaacaactc cagtctgctt
6841 cctttcagca tgataaagag atgctccaag cgcaggtgag ggcaaccaag cagctgcaat
6901 ctgaaatgat agccctaaaa cagggggttt tggccgcagg cggcttttcc cccactgatg
6961 cagcaagggg atccattggt gcacccatga caaaggtgct tgactggtct ggcactcgat
7021 actgggcgcc caattccaca aagacaactg gctattcggg acaatttacc tcttcacctg
7081 tgcatatgtc tagcccaaat gctccacaat caaaacctgc aaagcctagg tctctagctc
7141 cttcctcttc ttctagcagt gtctatagta tgtatactca atctactcat ttgacatctg
7201 gctcttctag taatgcttct tctgcctcta caaaattgac aaatttaagc tctggctcct
7261 ctcaaaacag aacagcagag tgggtaaatc aacagagaag tcttagccct tttatgagtg
7321 gcgcacttaa catctcacat gtcacgccac cctcaagtag ggcttccagt tctgggacgg
7381 tctcgaccgt gcccaaggaa gttttggact cctggacgtc tgcgtttaac acacacagac
7441 agccgctctt cgcacacctc agagtgaggg gggagtcacg tgtttagtga aaagaaataa
7501 ttggctataa tgtgatttct tt
//