Typing tool
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Typing tool
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Complete norovirus genomes
| PV750899 | GII.17 | |
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| GII.P17 |
ORF1: 1..5102
ORF2: 5083..6702
ORF3: 6702..7481
LOCUS PV750899 7527 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate CNM_2_2022_Spain_GII17P17 nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION PV750899
VERSION PV750899.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7527)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7527)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7527
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="CNM_2_2022_Spain_GII17P17"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Murcia"
/collection_date="May-2022"
/note="genotype: GII.17"
gene <1..5102
/gene="ORF1"
CDS <1..5102
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUS55933.1"
/translation="ASNDASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGARSKQ
PPPGETKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVVQPD
AQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAIS
LAKIEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDIIGK
LRPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAREL
AKKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEK
AKRDFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARA
SGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTL
DELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALHHLR
SARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDRGGC
PKPRDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGRLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSP
SLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEG
TVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGP
NHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQE
SMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..992
/gene="ORF1"
/product="p48"
mat_peptide 993..2090
/gene="ORF1"
/product="NTPase"
mat_peptide 2091..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RdRp"
gene 5083..6702
/gene="ORF2"
CDS 5083..6702
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55934.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPTGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISNNDDFQFQPTKFTPVGVN
DDDDHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIIDC
LIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVV
PANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6702..7481
/gene="ORF3"
CDS 6702..7481
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55935.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNVSSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSPGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 tggcgtctaa cgacgcttcc gctgccgttg ctggcaaaaa caacaacaac gacaaggaaa
61 aatcttcaag tgacagcttg tttgctaaca tgtctgtcac ttttaagaaa gccctcgggg
121 cgcggtctaa acaaccgccc ccgggagaaa caaaacaaat acaaaaacca ccaaggccac
181 cgacaccgga attggtgaag agaatacctc cacccccacc caatggcgag gatgaaccag
241 ggatagtgta caaggtggga gagggcgtgt ctgggctgcc cgacctaaca actgtggtac
301 aacctgacgc acaaaacaca gcttatagtg ttcccccact tagccagaga gaagtcggcg
361 aagctaaaga accgctgcct ggctccatcc tggaaatgtg ggatggtgag atctaccact
421 atgggctgta tgttgagcgg gggcatgtgc tcggagtaca caaaccacct gctgcaataa
481 gccttgccaa aattgaaata acaccgctgt ctctctactg gagagtggtc tacactcccc
541 agtatttgat agatccagga actcttaaga acttgagtgg agagactttc ccatacacgg
601 cctttgacaa caactgttat gccttctgtt gttgggtcct agacctcaac gactcctggc
661 ttagcaggag aatgatccaa agaacaactg gattcttcaa accttatcag gattggaaca
721 gaaaaccctt accaaccatg gatgaaccga aaatcaagaa ggccgcgaat gctgtcctat
781 gcgctctctc ctcactcttc actaggccca ttaaggacat cattggaaag cttagaccac
841 tgaacattct taatatactg gcaacctgcg attggacttt tgcaggcata gtggaatcct
901 tgatccttct tgctgaactc tttggggtgt tctggacacc cccagatgtg tctgcgatga
961 ttgctccctt actcggtgac tacgagatgc aaggccccga agacctggcc gtggaacttg
1021 tacccgtggt gatgggagga ataggtttgg tgttaggatt caccaaagaa aagatcggca
1081 agatgctttc atcagctgcg accacactta gggcctgcaa ggatctagga tcttatggat
1141 tggagatact caaattggtc atgaagtggt tcttccccaa gaaggaggag gctaacgaac
1201 tagccatggt gagggccatt gaggatgcag tcctggattt ggaggcaata gaaaacaatc
1261 acatgaccac ccttctcaag gataaagaca gcctggccac atacatgagg acccttgact
1321 tggaagaaga gaaagcaagg aaactgtcaa ccaaatcggc gtcacctgac atcgtgggca
1381 caataaacgc attgttggct aggatagcag ccgccaggtc actggtccac aaggctaagg
1441 aggagctctc gagcagacag agacctgttg ttgtaatgat atcaggcaga ccaggtatag
1501 gaaagaccca tctggccaga gagctagcca agaaagttgc gtcaacactg tcaggcgacc
1561 aaaggattgg actggtacct aggaatggcg tcgaccattg ggacgcctac aagggagaaa
1621 gggtggtcct gtgggatgat tatggtatga gcaaccctat acaggacgca ctgaggctcc
1681 aagaattggc tgacacctgt cctctgaccc taaattgtga taggattgaa aacaaaggaa
1741 aagtgttcga cagtgatgcc ataattataa caaccaacct tgcaaaccca gcaccactag
1801 actatgtcaa ctttgaggcc tgttctagac gcatagactt cttggtgtat gcagacgcac
1861 ctgacattga gaaggctaag cgtgacttcc ctggccaacc agatatgtgg aaagaccatt
1921 tcagaccaga cttctcacac attaaacttc agctggcacc acagggaggt tttgacaaaa
1981 atggcaacac cccacatggc aaaggtgtgg taaagtccct gacgattggt tctctgatcg
2041 ccagggcctc cggcttgctc cacgagagaa tggatgaatt cgagctccaa ggctctgacc
2101 tgccaacctt caattttgac cgcaacaaag tcgccgcctt cagacaatta gcagctgaaa
2161 acaaatatgg tcttatggac acattgaggg tcggcaacca actgaaaagt gttaagaccc
2221 tggatgagct gaagcaggcc ataaagaaca tcagtatcaa gaagtgtcag atagtgtata
2281 atggatgcac ctataccatg gaatctgatg ggaggggcaa ggttgtggtt gaaaaggtac
2341 aaaacgcaac agttcaaacc aacaatgaac ttgtaggggc gctccaccac ctgagatctg
2401 caaggataag atactatgtt aaatgtttcc aagaagccat ttactctcta ctccaaattg
2461 ctggtgcagc ctttgtcacc tcacgcatcg tgaggcgcat gaacatatca aatctctggt
2521 cgaagccacc catcgaggag ggtgatgagc ctgaagacag aggaggatgc cccaagccca
2581 gggatgaaga tgacctcact attgactcta gagacattaa agtggaaggg aagaagggca
2641 agaacaagtc tggccggggc aagaaacaca cagccttctc ttccaagggc ctcagtgatg
2701 aagagtacga tgagtacaag agaatcagag aggagaggaa tggcaaatac tcaatagagg
2761 aatacctcca agatagggac agatactatg aagagcttgc cattgctaag gccactgagg
2821 aggacttctg tgaggaggag gagatcaaaa tccgccagag aatcttccga cccaccagga
2881 agcagcggaa agaggaaagg gccacgcttg ggcttgtcac aggatcggaa atcagaaaga
2941 ggaatccaga tgactttaaa ccaaaaggaa gattgtgggc tgatgacaac aggagcgtgg
3001 attacaatga gaggatagat tttgaggctc ccccgagcgt ttggtctagg atagtcaact
3061 ttggcacagg ttggggattc tgggtttctc caagtctctt tataacttca acacacgtca
3121 taccaaaagg aatcactgag gcctttggag tgcccataaa ccaaatccaa attcacaaat
3181 ctggagaatt ttgccgcttg cggtttccaa agccaattag accagacgtg agtgggatga
3241 tcttggaaga gggcgcccct gaaggcactg ttgtgtctat tctcatcaaa aggacaacag
3301 gggagctgat gcctcttgca gtcagaatgg ggactcatgc cacaatgaaa atccaaggta
3361 gaacggtggg tggtcagatg ggtatgcttc tcactggctc aaatgctaaa ggcatggatc
3421 taggcacaac gccaggtgac tgcggatgtc catacatata caaaaggggc aatgaccttg
3481 tggtcattgg ggtgcacact gcagcagctc gtggaggcaa cacggtcata tgtgccacac
3541 agggaagtga aggcgaagcc actcttgaag gaggtgacaa caagggtacc tattgtggag
3601 cccccatttt gggacctggc aatgcaccaa aattgagcac aaagacaaaa ttctggagat
3661 cctctaacgc accgcttccc ccaggtactt atgaaccagc ataccttggt gggagagacc
3721 cgcgcgtgaa aggaggccca tctctgcaac aagttatgag agaccaactt aaacctttta
3781 cagagcccag agggaagcca ccaaacccaa atgtcttaga gtcagcaaag aagactatca
3841 tcaatgttct ggaacaaacc attgaccccc ctcaaaagtg gtcatatgcc caagcttgtg
3901 catccctcga caagacaacc tccagtggat acccgcacca cgtccggaag aatgactatt
3961 ggagtggtga atccttcaca ggaaaacttg cagatcaggc ttcaaaagca aatctcatgt
4021 atgaggaagg caagcacatg caaccagttt acaccgcagc actcaaagac gagctcgtga
4081 aaactgacaa aatttatggc aaaatcaaga aaagactcct gtggggttct gacctctcca
4141 caatgattcg atgcgccaga gcatttggtg gtctcatgga tgaattcaaa gcaaattgca
4201 ttacactccc tatcagagtt ggtatgaata tgaatgaaga tggtcccata atatttgaga
4261 aacactccag gtacaggtac cactatgatg ctgattactc ccgctgggac tccacacaac
4321 agcgggcagt gctggaagcg gcacttgaaa tcatggtgag gttttctgct gagccacagc
4381 tggcacaaat agtggcagag gacctgctgt caccaagtgt ggttgatgtg ggcgatttca
4441 aaatcgctat caatgaaggc ctaccatctg gcgtgccttg cacctcacaa tggaattcta
4501 ttgcccactg gttacttacc ttgtgtgccc tttctgaagt gacaggatta ggtcctgaca
4561 tcatacaagc taactccatg tactctttct atggtgatga tgagattgtg agcacagaca
4621 taaaattgga cccagagaaa ttgaccgcaa agctcaaaga atatggtctt aaacccactc
4681 ggcccgacaa aactgagggg ccgttggtga ttagtgagga cctgaatggg ttgactttcc
4741 tccgccgaac agtcacccgt gatccagcag gttggtttgg aaagttggac caaaactcca
4801 tcctcaggca gttgtactgg acaagaggac ccaaccatga agaccccagt gagaccatga
4861 taccacacgc acaaagacct gtgcagctca tggcactact aggagaatcc tccctacatg
4921 gaccctcatt ttacagcaag gttagcaaat tagtcatatc tgaacttaaa gagggaggaa
4981 tggattttta tgtgcccaga caagagtcaa tgttcagatg gatgaggttc tcagatctaa
5041 gcacatggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
5101 gacgccgctc catctaatga tggtgctgct ggtctcgtac cagagggcaa caacgagacc
5161 cttcccctag aaccagttgc gggcgcagct atagccgcac ccgtcactgg ccaaaataat
5221 ataattgacc cctggattag aacaaatttt gtgcaagcac caaatggaga gttcacagtg
5281 tcacccagaa actctcctgg agaaatttta ttaaacttag agttgggccc tgatttgaac
5341 ccttatttgg ctcatttgtc aaggatgtac aatgggtatg ctggtggagt ggaagttcag
5401 gttctcctgg cagggaacgc gttcactgcc ggaaagatcc tcttcgccgc cgtcccgcca
5461 aatttcccag tggaattctt aagcccagcc cagatcacaa tgctcccaca tttaatagta
5521 gatgttagga ctcttgaacc aattatgatc ccactccctg atgttaggaa tacattcttc
5581 cattatagta accagcctaa cagccgcatg agattagtgg ctatgctcta caccccactc
5641 agatctaatg gctcaggtga tgatgtcttt actgtctctt gcagggtttt gaccaggcct
5701 actcctgatt ttgagttcac ttatttagtg ccaccttctg ttgaatctaa aactaagcct
5761 ttttccttac ctattttaac cctttctgag ctcacaaatt cgaggtttcc agtccccatc
5821 gattcgcttt tcaccgccca gaataatgtg ttgcaggtgc agtgtcaaaa tggcaggtgt
5881 acacttgatg gtgagttaca aggcacaacc cagttgctcc caactggcat ctgtgcattc
5941 aggggacggg tgacagcaca aattaaccaa cgtgacaggt ggcacatgca actgcaaaac
6001 ctcaatggta caacatatga cccaactgat gatgtgccag ccccgctggg tacacctgac
6061 ttcaagggcg tcgtgtttgg gatggtaagc caaagaaatg tgggtaatga tgcgcctggc
6121 tcaaccagag cccaacaggc gtgggtttca acctatagcc cccaatttgt ccccaaatta
6181 ggttctgtca atcttagaat tagtaataat gatgatttcc aattccagcc gacaaaattc
6241 acaccagtgg gcgtcaatga tgacgatgac cacccgttca gacagtggga actaccaaac
6301 tattcagggg agcttacctt gaatatgaat cttgcccccc cagttgctcc aaattttcct
6361 ggtgaacaat tgttattctt caggtctttc gtgccatgct cgggaggtta caaccaaggt
6421 attatagatt gtcttatccc ccaagaatgg atccaacact tctatcagga atcagcaccc
6481 tcccagtcag acgtggccct aatcaggtat gttaaccccg atacgggacg tacactgttt
6541 gaagcaaaat tgcacagatc tggttacatt actgtggctc actctggaga ctatcctctt
6601 gttgttccgg ctaatggaca ctttagattt gattcttggg taaatcagtt ttactcactc
6661 gccccaatgg gaactgggaa tgggcgaagg agggctcagt aatggctggg gctttcattg
6721 caggattggc aggcgacatg ctcacgtcat ctgtgggctc ccttgtgaac gcaggggcaa
6781 acgccatcaa ccaaaagata gactttgaaa acaacaaaca actccagtct gcttcctttc
6841 agcatgataa agagatgctc caagcgcagg tgagggcaac caagcagctg caatctgaaa
6901 tgatagccct aaaacagggg gttttggccg caggcggctt ttcccccact gatgcagcaa
6961 ggggatccat tggtgcaccc atgacaaagg tgcttgactg gtctggcact cgatactggg
7021 cgcccaattc cacaaagaca actggctatt cgggacaatt tacctcttca cctgtgcata
7081 tgtctagccc aaatgctcca caatcaaaac ctgcaaagcc taggtctcta gctccttcct
7141 cttcttctag cagtgtctat agtatgtata ctcaatctac tcatttgaca tctggctctt
7201 ctagtaatgt ttcttctgcc tctacaaaat tgacaaattt aagctctggc tcctctcaaa
7261 acagaacagc agagtgggta aatcaacaga gaagtcttag cccttttatg agtggcgcac
7321 ttaacatctc acatgtcacg ccaccctcaa gtagggcttc cagtcctggg acggtctcga
7381 ccgtgcccaa ggaagttttg gactcctgga cgtctgcgtt taacacacac agacagccgc
7441 tcttcgcaca cctcagagtg aggggggagt cacgtgttta gtgaaaagaa ataattggct
7501 ataatgtgat ttctttctaa atttggc
//