Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| PV750898 | GII.17 | |
|
|---|---|---|---|
| GII.P17 |
ORF1: 2..5110
ORF2: 5091..6707
ORF3: 6707..7486
LOCUS PV750898 7552 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_29_ONCO nonstructural polyprotein
(ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION PV750898
VERSION PV750898.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7552)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7552)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7552
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_29_ONCO"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="23-Feb-2024"
/note="genotype: GII.17"
gene 2..5110
/gene="ORF1"
CDS 2..5110
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XUS55930.1"
/translation="MKMASNDASVAVAGKNNNNDNVKSSNDSLFSNMTVTFKKALGAR
SKQPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVA
QPDAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDV
IGKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARK
LSSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALH
HLRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDK
GGCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 2..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2635
/gene="ORF1"
/product="p22"
mat_peptide 2636..3034
/gene="ORF1"
/product="VPg"
mat_peptide 3035..3577
/gene="ORF1"
/product="Pro"
mat_peptide 3578..5107
/gene="ORF1"
/product="RdRp"
gene 5091..6707
/gene="ORF2"
CDS 5091..6707
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55931.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6707..7486
/gene="ORF3"
CDS 6707..7486
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55932.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 aatgaagatg gcgtctaacg acgcttccgt tgccgttgct ggcaaaaaca acaacaacga
61 caatgtaaaa tcttcaaatg acagcttgtt ttctaacatg actgttactt ttaagaaagc
121 cctcggggcg cggtctaagc agccgccccc gggagaaaca aaacaaacac taagaccacc
181 aaggccgccg acaccggaat tggtgaagaa gataccccca ccccccccca atggcgagga
241 tgaaccaaag gtaacgtata aggtgggaga aggtgtgtct gggctgcccg acttaacaac
301 cgtggcacaa cctgacgcac agaacacagc ctatagtgtc cccccactta gccagagaga
361 ggtcggcgaa gctagagaac cgttgcctgg ctccattctg gaaatgtggg atggtgagat
421 ctaccactat gggctgtatg ttgagcgggg gcatgtgctg ggagtgcaca aaccacctgc
481 tgcaataagc cttgccaaaa ttgagttaac accgctgtct ctctactgga gagtggtcta
541 cactccccag tacttgatag ctccagagac cctcaagaat ttaaatggag agactttccc
601 atacacggcc tttgacaaca actgttatgc cttctgttgt tgggttctag acctcaacga
661 ctcctggctt agcagaagaa tggtccaaag aacaaccgga ttcttcagac cgtatcagga
721 ctggaacaga aaacccttac caaccatgga tgaaccaaaa atcaagaagg ccgcgaatgc
781 tgttctgtgt gctctctcct cactcttcac taggcccatc aaagatgtca ttggaaagct
841 taaaccacta aacattatga acatactggc aacttgtgat tggacttttg cgggcatagt
901 ggaatccatg atccttcttg ctgaactctt tggggtgttc tggacgcccc cagatgtgtc
961 tgcaataatt gctcccttac tcggtgacta cgagatgcaa ggccccgaag acctggccgt
1021 ggaacttgtg cccgtggtaa tgggaggaat aggtttggtg ttaggattca ccaaggaaaa
1081 gatcggcaag atgctttcat cagctgcaac cacactcagg gcctgtaagg atctaggatc
1141 ttatgggttg gagatactca aactggtcat gaagtggttc ttccccaaga aggaggaggc
1201 caacgagtta gccatggtga gggccattga ggatgcagtt ctggatttgg aggcaataga
1261 aaacaaccac atgaccactc tccttaagga caaagacgcc ctggccacat acatgaggac
1321 tcttgacttg gaagaagaaa aagcaaggaa actatcttcc aaatcggcgt cacctgacat
1381 cgtgggcaca gtaaacgcat tattggcaag aatagcagcc gccaggtcac tggtccacaa
1441 ggctaaggag gagctctcga gcagacagag acctgttgtt gtaatgatat caggtaggcc
1501 aggtatagga aagacccatc tggccagaga gctagccaag aaggttgcgt caacactgtc
1561 aggcgaccaa aggattggac tgatacccag aaatggcgtc gaccattggg acgcctacaa
1621 aggagagcgg gtggttctgt gggatgacta tggcatgagc aaccctatac aggacgcact
1681 gaggctccaa gaattggctg acacctgtcc tctgacccta aattgtgaca gaattgaaaa
1741 caaaggaaaa gtgttcgaca gtgacgccat aatcataacg accaatcttg caaacccagc
1801 accattggat tatgtcaact ttgaggcttg ttccagacgc atagacttct tggtgtatgc
1861 agacgcacct gacatcgaga aggctaagcg tgacttccct ggccaaccag atatgtggaa
1921 agaccattac agaccagact tctcacacat taaacttcag ctcgcaccac agggaggctt
1981 tgataagagt ggcaacaccc cacatggcaa aggtgtggtt aagtctctga cgattggttc
2041 tctgatcgcc agggcttctg gcttgctcca tgagagaatg gatgaattcg agctccaagg
2101 ccccaactta ccaaccttca atttcgaccg taacaaagtc gccgccttca gacaattggc
2161 agctgaaaac aaatacggtc ttatggacac actgagggtc ggcaaccaac tgaaaagtgt
2221 caaaaccctg gatgagctga agcaggctat aaagaacatc accatcaaga agtgccagat
2281 agtgtacaat ggatgcacct acaccatgga atctgatggg aggaacaagg ttgtggttga
2341 aaaggttcaa aatgcaacag tccaaaccaa caatgagctt gcaggagcac tccaccacct
2401 gagatctgca agaataaggt attatgtcaa atgtttccaa gaagctattt actctatact
2461 ccaaattgct ggtgcagcct tcgtcaccac acgcatcgtg aggcgcatga acatctcaaa
2521 cctctggtcg aagccacccg tcgaagaggg tgatgagcct gaagacaaag gggggtgccc
2581 caagcccagg gatgaagatg acctcactat tgactccaaa gacattaaag cagaaggtaa
2641 gaagggcaag aacaaatctg gccggggcaa gaaacacaca gctttctcat ccaagggcct
2701 cagtgatgaa gagtacgatg agtacaagag aatcagggag gagagaaatg gcaagtactc
2761 aatagaagaa tacctccagg atagggatag atactatgaa gagcttgcca ttgctaaggc
2821 cactgaggaa gacttctgtg aagaggagga aatcaaaatt cgccagagaa tcttccggcc
2881 caccaggaaa cagcggaaag aggaaagagc cacgcttggg ctcgtcacag gatcggaaat
2941 cagaaagagg aacccagatg attttaagcc aaaaggaaaa ttgtgggctg atgacaacag
3001 gagtgtggac tacaatgaga ggatagattt tgaggctccc ccaagtgttt ggtctaggat
3061 agtcaacttt ggtacagggt ggggattctg ggtctcccca agtctcttta taacttcaac
3121 acatgtcata ccaaaaggaa tcactgaggc ctttggagtt cctattaacc aaattcaaat
3181 tcacaaatct ggagagtttt gccgcttgcg gtttccaaaa ccaatcaggc cagacgtgag
3241 tggaatgatc ttggaagagg gtgcccctga aggcactgtt gtttccattc tcatcaagag
3301 gacgacaggg gaactgatgc ctctcgcagt cagaatggga actcatgcca caatgaaaat
3361 ccaaggtaga acggtgggcg gtcaaatggg catgcttctc actggctcaa acgccaaaag
3421 catggaccta ggcacaacac caggtgactg tgggtgccca tacatataca aaaggggcaa
3481 tgacttcgtg gtcattgggg tgcacactgc agcagcccgt ggaggtaaca cggtcatatg
3541 tgccacacag gggagtgaag gcgaagccac cctcgaagga ggtgacaaca agggcaccta
3601 ttgtggagcc cccatcttgg gtcctggcaa cgcaccaaaa ttgagcacaa aaacaaaatt
3661 ctggagatct tctaacgcgc cgctcccgcc aggcacctat gaaccagcat accttggtgg
3721 aaaagacccg cgtgtgaagg gaggcccatc tctacaacag gttatgagag accaactcaa
3781 accttttaca gagcccagag ggaagccacc aaaaccaagt gtcctagaat cagcaaagaa
3841 gaccatcatt aatgttctgg aacaaaccat tgacccccct gaaaagtggt catatgccca
3901 agcttgtgca tccctcgaca agacaacctc cagtggatac ccgcatcacg tccggaagaa
3961 tgactactgg agtggtgaat ccttcacggg gaaacttgca gaccaggcct caaaagcaaa
4021 tctcatgtat gaggaaggta agcacatgca accagtttac accgcagcac tcaaagacga
4081 gctcgtgaaa actgacaaaa tttatggcaa gatcaagaaa agactcctgt ggggctctga
4141 cctatccacc atgattcgat gcgccagggc atttggtggc ctcatggacg agctcaaagc
4201 aaattgtatc acactcccta tcagagttgg tatgaacatg aatgaagatg gtcccataat
4261 atttgaaaag cactccaggt acaggtacca ctatgatgct gattattccc gctgggattc
4321 cacacaacag cgggcagtgc tggaagcggc acttgaaatc atggtgagat tttctgctga
4381 gccacagttg gcacaaatag tggcagagga cctgctatca ccaagtgtgg ttgatgtggg
4441 cgatttcaaa attactatta atgaaggcct accatctggc gtgccttgca cttcacaatg
4501 gaattctatt gcccactggt tactcaccct atgtgccctg tctgaagtga caggactagg
4561 ccctgacatc atacaagcca actccatgta ctctttctat ggtgatgatg agattgtgag
4621 cacagacata aaattagacc cagagaaatt gactgcaaaa ctcaaagaat atggtcttaa
4681 acccacccgg cctgacaaga ctgaggggcc actggtaatt agtgaggacc tgaatgggtt
4741 gactttcctc cgccgaacag tcacccgcga tccagcgggt tggtttggaa agttggacca
4801 aaactccatc ctcagacagc tgtactggac aaggggaccc aaccatgaag accccagtga
4861 gactatgata ccacacgcac agagacctgt gcagctcatg gcattgctag gagaatcctc
4921 cctacatgga ccctcatttt acagcaaggt tagcaagctg gttatatctg aacttaaaga
4981 gggaggaatg gatttttatg tgcccagaca agagtcaatg ttcaggtgga tgaggttctc
5041 agatctaagc acatgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg
5101 cgtcgaatga cgccgctcca tctaatgatg gtgctgctgg tctcgtacca gagggcaata
5161 acgagaccct tcccctagaa ccagttgcgg gcgcagccat agccgcaccc gtcactggcc
5221 aaaataatat aattgacccc tggattagaa caaattttgt gcaagcacca aatggagagt
5281 tcacagtgtc acccagaaac tctcctggag aaattttact aaacctagag ttgggccctg
5341 atctgaaccc ttatttggct catttgtcaa ggatgtataa tggatatgct ggtggagttg
5401 aagtccaggt tctcctggca gggaacgcgt tcactgccgg gaagatcctc ttcgccgctg
5461 tcccgccaaa ttttccggtg gaattcttaa gcccagccca gattacaatg ctcccacata
5521 taatagtaga tgttaggact cttgaaccaa ttatgatccc attacctgat gttaggaata
5581 cattcttcca ctataataat cagcccaaca gccgcatgag attagtggct atgctctaca
5641 ccccccttag atctaatggc tcaggtgatg atgttttcac tgtttcttgc agggttttga
5701 ctaggcctac tcctgatttt gagttcactt atctagtgcc accctctgtt gaatctaaga
5761 ctaaaccctt ttctttaccc attctaaccc tttctgagct cacaaattcg aggttcccgg
5821 tccccatcga ttcgcttttc accgcccaaa ataatgtgtt gcaggtgcag tgtcaaaatg
5881 gcaggtgcac acttgacggt gagctacaag gcacaaccca gttgctccca tctggcatct
5941 gtgcgttcag gggacgggtg acagcagaaa ctgacaatcc tgacaagtgg cacatgcaac
6001 tgcaaaacct taatggcaca acatatgacc caactgatga tgtgccagcc ccactgggta
6061 cacctgactt caagggcgtc gtgtttggga tggcaagcca aagaaatgtg ggtaacgacg
6121 cgcccggctc aaccaggtcc catgaggcgg tgatttcaac ctacagcccc agatttgttc
6181 ctaaattagg ctctgtcaat ttcaaaagca atgacgatga tttccaattg cagccaacaa
6241 gattcacacc agtgggcatt aatgatgatg gcaaccaacc attcagacaa tgggaactac
6301 cagattattc aggggtgctt accttgaata tgaaccttgc cccccctgtt gctccaaatt
6361 tccctggcga acaattacta ttcttcagat cttctgtgcc atgttcagga ggttacaacc
6421 aaggtattat agattgcctt atcccccaag aatggatcca acatttctac caggaatcag
6481 caccttctca gtcagaagtg gccctaatca ggtacgtcaa ccccgacacg ggtcgtacac
6541 tgtttgaggc aaaattgcat aggtcaggct atatcactgt ggctcattct ggagactatc
6601 ctcttgttgt tccggctaat ggatatttta gatttgactc ttgggtaaat cagttttact
6661 cactcgcccc aatgggaact gggaatgggc gaaggagggc tcagtaatgg ctggagcttt
6721 cattgcagga ttggcgggtg acatgctcac gtcatccgtg ggctccctgg tgaacgcagg
6781 ggcaaacgcc atcaaccaaa agatagactt tgaaaacaac aaacaactcc agtctgcttc
6841 ctttcaacat gataaagaga tgctccaagc gcaggtgaac gcaaccaagc agctgcaatc
6901 tgagatgata gccctaaaac agggggtttt ggccgcaggc ggcttttccc ccactgatgc
6961 agcgaggggg gccatcggtg cacccatgac aaaggtgctt gactggtctg gcactcgata
7021 ctgggctccc aattccacaa agacaactgg ttattcgggg caattcacct cttcacctgt
7081 gcacatgccc agcccgagtg tcccacaatc aaaacccgca aagcccaagt ctctaggttc
7141 ttcttcttct tctagtagtg tttacagtat gtctacccaa ttaacttctc taacatctgg
7201 ctcttctagt aatgcttctt ctgcttctac aaaattgaca aatttgagct ccggctcttc
7261 tcaaaacaga acagcagagt gggtgaacca acagagaagt ctcagccctt tcatgagtgg
7321 cgcactcaat atctcgcatg tcacgccacc ttcaagtagg gcctccagtt ctgggacggt
7381 ctcaaccgtg cccaaggaag ttttggactc ctggacatct gcattcaaca cacgcagaca
7441 gccgctcttc gcacacctca gagtgagggg ggagtcacgt gtttagtgaa aagaaataat
7501 tggctataat atgatttctt taaaatttaa atttggctaa tttgtatctt tt
//