Typing tool
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Typing tool
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Complete norovirus genomes
| PV750895 | GII.17 | |
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| GII.P17 |
ORF1: 1..5103
ORF2: 5084..6700
ORF3: 6700..7479
LOCUS PV750895 7545 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_20_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750895
VERSION PV750895.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7545)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7545)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7545
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_20_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="18-Feb-2024"
/note="genotype: GII.17"
gene <1..5103
/gene="ORF1"
CDS <1..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XUS55921.1"
/translation="MASNDASVAVAGKNNNNDNVKSSSDSLFSNMTVTFKKALGARSK
QPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVMYKVGEGVSGLPDLTTVAQP
DAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIG
KLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLS
SKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHL
RSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGG
CPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGL
VTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPYHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIIVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..993
/gene="ORF1"
/product="p48"
mat_peptide 994..2091
/gene="ORF1"
/product="NTPase"
mat_peptide 2092..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6700
/gene="ORF2"
CDS 5084..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55922.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6700..7479
/gene="ORF3"
CDS 6700..7479
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55923.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVHSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 atggcgtcta acgacgcttc cgttgccgtt gctggcaaaa acaacaacaa cgacaatgta
61 aaatcttcaa gtgacagctt gttttctaac atgactgtta cttttaagaa agccctcggg
121 gcgcggtcta agcagccgcc cccgggagaa acaaaacaaa cactaagacc accaaggccg
181 ccgacaccgg aattggtgaa gaagataccc ccaccccccc ccaatggcga ggatgaacca
241 aaggtaatgt ataaggtggg agaaggtgtg tctgggctgc ccgacttaac aactgtggca
301 caacctgacg cacagaacac agcctatagt gtccccccac ttagccagag agaggtcggc
361 gaagctagag aaccgttgcc tggctccatt ctggaaatgt gggatggtga gatctaccac
421 tatgggctgt atgttgagcg ggggcatgtg ctgggagtgc acaaaccacc tgctgcaata
481 agccttgcca aaattgagtt aacaccgctg tctctctact ggagagtggt ctacactccc
541 cagtacttga tagctccaga gaccctcaag aatttaaatg gagagacttt cccatacacg
601 gcctttgaca acaactgtta tgccttctgt tgttgggttc tagacctcaa cgactcctgg
661 cttagcagaa gaatggtcca aagaacaacc ggattcttca gaccgtatca ggactggaac
721 agaaaaccct taccaaccat ggatgaacca aaaatcaaga aggccgcgaa tgctgttctg
781 tgtgctctct cctcactctt cactaggccc atcaaagatg tcattggaaa gcttaaacca
841 ctaaacatta tgaacatact ggcaacttgt gattggactt ttgcgggcat agtggaatcc
901 atgatccttc ttgctgaact ctttggggtg ttctggacgc ccccagatgt gtctgcaata
961 attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc cgtggaactt
1021 gtgcccgtgg taatgggagg aataggtttg gtgttaggat tcaccaagga aaagatcggc
1081 aagatgcttt catcagctgc aaccacactc agggcctgta aggatctagg atcttatggg
1141 ttggagatac tcaaactggt catgaagtgg ttcttcccca agaaggagga ggccaacgag
1201 ttagccatgg tgagggccat tgaggatgca gttctggatt tggaggcaat agaaaacaac
1261 cacatgacca ctctccttaa ggacaaagac gccctggcca catacatgag gactcttgac
1321 ttggaagaag aaaaagcaag gaaactatct tccaaatcgg cgtcacctga catcgtgggc
1381 acagtaaacg cattattggc aagaatagca gccgccaggt cactggtcca caaggctaag
1441 gaggagctct cgagcagaca gagacctgtt gttgtaatga tatcaggtag gccaggtata
1501 ggaaagaccc atctggccag agagctagcc aagaaggttg cgtcaacact gtcaggcgac
1561 caaaggattg gactgatacc cagaaatggc gtcgaccatt gggacgccta caaaggagag
1621 cgggtggttc tgtgggatga ctatggcatg agcaacccta tacaggacgc actgaggctc
1681 caagaattgg ctgacacctg tcctctgacc ctaaattgtg acagaattga aaacaaagga
1741 aaagtgttcg acagtgacgc cataatcata acgaccaacc ttgcaaaccc agcaccattg
1801 gattatgtta actttgaggc ttgttccaga cgcatagact tcttggtgta tgcagacgca
1861 cctgacatcg agaaggctaa gcgtgacttc cctggccaac cagatatgtg gaaagaccat
1921 tacagaccag acttctcaca cattaaactt cagctcgcac cacagggagg ctttgataag
1981 agtggcaaca ccccacatgg caaaggtgtg gttaagtctc tgacgattgg ttctctgatc
2041 gccagggctt ctggcttgct ccatgagaga atggatgaat tcgagctcca aggccccaac
2101 ttaccaacct tcaatttcga ccgtaacaaa gtcgccgcct tcagacaatt ggcagctgaa
2161 aacaaatacg gtcttatgga cacactgagg gtcggcaacc aactgaaaag tgtcaaaacc
2221 ctggatgagc tgaagcaggc tataaagaac atcaccatca agaagtgcca gatagtgtac
2281 aatggatgca cctacaccat ggaatctgat gggaggaaca aggttgtggt tgaaaaggtt
2341 caaaatgcaa cagtccaaac caacaatgaa cttgcaggag cactccacca cctgagatct
2401 gcaagaataa ggtattatgt caaatgtttc caagaagcta tttactctat actccaaatt
2461 gctggtgcag ccttcgtcac cacacgcatc gtgaggcgca tgaacatctc aaacctctgg
2521 tcgaagccac ccgtcgaaga gggtgatgag cctgaagaca aaggggggtg ccccaagccc
2581 agggatgaag atgacctcac tattgactcc aaagacatta aagcagaagg taagaagggc
2641 aagaacaaat ctggccgggg caagaaacac acagctttct catccaaggg cctcagtgat
2701 gaagagtacg atgagtacaa gagaatcagg gaggagagaa atggcaagta ctcaatagaa
2761 gaatacctcc aggataggga tagatactat gaagagcttg ccattgctaa ggccactgag
2821 gaagacttct gtgaagagga agaaatcaaa attcgccaga gaatcttccg gcccaccagg
2881 aagcagcgaa aagaggaaag agccacgctt gggctcgtca caggatcgga aatcagaaag
2941 aggaacccag atgattttaa gccaaaagga aaattgtggg ctgatgacaa caggagtgtg
3001 gactacaatg agaggataga ttttgaggct cccccaagtg tttggtctag gatagtcaac
3061 tttggtacag ggtggggatt ctgggtctcc ccaagtctct ttataacttc aacacatgtc
3121 ataccaaaag gaatcactga ggcctttgga gttcccatta accaaattca aattcacaaa
3181 tctggagagt tttgccgctt gcggtttcca aaaccaatca ggccagacgt gagtggaatg
3241 atcttggaag agggtgcccc tgaaggcact gttgtttcca ttctcatcaa gaggacgaca
3301 ggggaactga tgcctctcgc agtcagaatg ggaactcatg ccacaatgaa aatccaaggt
3361 agaacggtgg gcggtcaaat gggcatgctt ctcactggct caaacgccaa aagcatggac
3421 ctaggcacaa caccaggtga ctgtgggtgc ccatacatat acaaaagggg caatgacttc
3481 gtggtcattg gggtgcacac tgcagcagcc cgtggaggta acacggtcat atgtgccaca
3541 caggggagtg aaggcgaagc caccctcgaa ggaggtgaca acaagggcac ctattgtgga
3601 gcccccatct tgggtcctgg caacgcacca aaattgagca caaaaacaaa attctggaga
3661 tcttctaacg cgccgctccc gccaggcacc tatgaaccag cataccttgg tggaaaagac
3721 ccgcgtgtga agggaggccc atctctacaa caggttatga gagaccaact caaacctttt
3781 acagagccca gagggaagcc accaaaacca agcgtcctag aatcagcaaa gaagaccatc
3841 attaatgttc tggaacaaac cattgaccca cctgaaaagt ggtcatatgc ccaagcttgt
3901 gcatccctcg acaagacaac ctccagtgga tacccgtatc acgtccggaa gaatgactac
3961 tggagtggtg aatccttcac ggggaaactt gcagaccagg cctcaaaagc aaatctcatg
4021 tatgaggaag gtaagcacat gcaaccagtt tacaccgcag cactcaaaga cgagctcgtg
4081 aaaactgaca aaatttatgg caagatcaag aaaagactcc tgtggggctc tgacctatcc
4141 accatgattc gatgcgccag ggcatttggt ggcctcatgg acgagctcaa agcaaattgt
4201 atcacactcc ctatcagagt tggtatgaac atgaatgaag atggtcccat aatatttgaa
4261 aagcactcca ggtacaggta ccactatgat gctgattatt cccgctggga ttccacacaa
4321 cagcgggcag tgctggaagc ggcacttgaa atcatagtga gattttctgc tgagccacag
4381 ttggcacaaa tagtggcaga ggacctgcta tcaccaagtg tggttgatgt gggcgatttc
4441 aaaattacta ttaatgaagg cctaccatct ggcgtgcctt gcacttcaca atggaattct
4501 attgcccact ggttactcac cctatgtgcc ctgtctgaag tgacaggact aggccctgac
4561 atcatacaag ccaactccat gtactctttc tatggtgatg atgagattgt gagcacagac
4621 ataaaattag acccagagaa attgactgca aaactcaaag aatatggtct taaacccacc
4681 cggcctgaca agactgaggg gccactggta attagtgagg acctgaatgg gttgactttc
4741 ctccgccgaa cagtcacccg cgatccagcg ggttggtttg gaaagttgga ccaaaactcc
4801 atcctcagac agctgtactg gacaagggga cccaaccatg aagaccccag tgagactatg
4861 ataccacacg cacagagacc tgtgcagctc atggcattgc taggagaatc ctccctacat
4921 ggaccctcat tttacagcaa ggttagcaag ctggttatat ctgaacttaa agagggagga
4981 atggattttt atgtgcccag acaagagtca atgttcaggt ggatgaggtt ctcagatcta
5041 agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggta ataacgagac
5161 ccttccccta gaaccagttg cgggcgcagc catagccgca cccgtcactg gccaaaataa
5221 tataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag agttcacagt
5281 gtcacccaga aactctcctg gagaaatttt actaaaccta gagttgggcc ctgatctgaa
5341 cccttatttg gctcatttgt caaggatgta taatggatat gctggtggag ttgaagtcca
5401 ggttctcctg gcagggaacg cgttcactgc cgggaagatc ctcttcgccg ctgtcccgcc
5461 aaattttccg gtggaattct taagcccagc ccagattaca atgctcccac atataatagt
5521 agatgttagg actcttgaac caattatgat cccattacct gatgttagga atacattctt
5581 ccactataat aatcagccca acagccgcat gagattagtg gctatgctct acacccccct
5641 tagatctaat ggctcaggtg atgatgtttt cactgtttct tgcagggttt tgactaggcc
5701 tactcctgat tttgagttca cttatctagt gccaccctct gttgaatcta agactaaacc
5761 cttttcttta cccattctaa ccctttctga gctcacaaat tcgaggttcc cggtccccat
5821 cgattcgctt ttcaccgccc aaaataatgt gttgcaggtg cagtgtcaaa atggcaggtg
5881 cacacttgac ggtgagctac aaggcacaac ccagttgctc ccatctggca tctgtgcgtt
5941 caggggacgg gtgacagcag aaactgacaa tcctgacaag tggcacatgc aactgcaaaa
6001 ccttaatggc acaacatatg acccaactga tgatgtgcca gccccactgg gtacacctga
6061 cttcaagggc gtcgtgtttg ggatggcaag ccaaagaaat gtgggtaacg acgcgcccgg
6121 ctcaaccagg tcccatgagg cggtgatttc aacctacagc cccagatttg ttcctaaatt
6181 aggctctgtc aatttcaaaa gcaatgacga tgatttccaa ttgcagccaa caagattcac
6241 accagtgggc attaatgatg atggcaacca accattcaga caatgggaac taccagatta
6301 ttcaggggtg cttaccttga atatgaacct tgccccccct gttgctccaa atttccctgg
6361 cgaacaatta ctattcttca gatcttctgt gccatgttca ggaggttaca accaaggtat
6421 tatagattgc cttatccccc aagaatggat ccaacatttc taccaggaat cagcaccttc
6481 tcagtcagaa gtggccctaa tcaggtacgt caaccccgat acgggtcgta cactgtttga
6541 ggcaaaattg cataggtcag gctatatcac tgtggctcat tctggagact atcctcttgt
6601 tgttccggct aatggatact ttagatttga ctcttgggta aatcagtttt actcactcgc
6661 cccaatggga actgggaatg ggcgaaggag ggctcagtaa tggctggagc tttcattgca
6721 ggattggcgg gtgacatgct cacgtcatcc gtgggctccc tggtgaacgc aggggcaaac
6781 gccatcaacc aaaagataga ctttgaaaac aacaaacaac tccagtctgc ttcctttcaa
6841 catgataaag agatgctcca agcgcaggtg aacgcaacca agcagctgca atctgagatg
6901 atagccctaa aacagggggt tttggccgca ggcggctttt cccccactga tgcagcgagg
6961 ggggccatcg gtgcacccat gacaaaggtg cttgactggt ctggcactcg atactgggct
7021 cccaattcca caaagacaac tggttattcg gggcaattca cctcttcacc tgtgcacatg
7081 cccagcccga gtgtcccaca atcaaaaccc gcaaagccca agtctctagg ttcttcttct
7141 tcttctagta gtgttcacag tatgtctacc caattaactt ctctaacatc tggctcttct
7201 agtaatgctt cttctgcttc tacaaaattg acaaatttga gctccggctc ttctcaaaac
7261 agaacagcag agtgggtgaa ccaacagaga agtctcagcc ctttcatgag tggcgcactc
7321 aatatctcgc atgtcacgcc accttcaagt agggcctcca gttctgggac ggtctcaacc
7381 gtgcccaagg aagttttgga ctcctggaca tctgcattca acacacgcag acagccgctc
7441 ttcgcacacc tcagagtgag gggggagtca cgtgtttagt gaaaagaaat aattggctat
7501 aatatgattt ctttaaaatt taaatttggc taatttgtat ctttt
//