Typing tool
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Typing tool
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Complete norovirus genomes
| PV750890 | GII.17 | |
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| GII.P17 |
ORF1: 1..5065
ORF2: 5046..6662
ORF3: 6662..7441
LOCUS PV750890 7507 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_14_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750890
VERSION PV750890.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7507)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7507)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7507
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_14_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="10-Feb-2024"
/note="genotype: GII.17"
gene <1..5065
/gene="ORF1"
CDS <1..5065
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XUS55906.1"
/translation="NNNNDNVKSSSDSLFSNMTVTFKKALGARSKQPPPGETKQTLRP
PRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVAQPDAQNTAYSVPPLS
QREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAKIELTPLSLY
WRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTG
FFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKPLNIMNILAT
CDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPEDLAVELVPVVMGG
IGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKEEANELAMVR
AIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLSSKSASPDIVGTVN
ALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTLSGDQ
RIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENK
GKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMW
KDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIARASGLLHERMDEFE
LQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDELKQAIKNITI
KKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLRSARIRYYVKCFQ
EAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGCPKPRDEDDLTID
SKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRD
RYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDD
FKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLFITSTHVIPK
GITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVVSILIKRTTG
ELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGND
FVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKTK
FWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLES
AKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGESFTGKLADQ
ASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGG
LMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLEAAL
EIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSIAHWLLT
LCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDKT
EGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGPNHEDPSETMIPH
AQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLS
TWEGDRNLAPSFVNEDGVE"
mat_peptide <1..955
/gene="ORF1"
/product="p48"
mat_peptide 956..2053
/gene="ORF1"
/product="NTPase"
mat_peptide 2054..2590
/gene="ORF1"
/product="p22"
mat_peptide 2591..2989
/gene="ORF1"
/product="VPg"
mat_peptide 2990..3532
/gene="ORF1"
/product="Pro"
mat_peptide 3533..5062
/gene="ORF1"
/product="RdRp"
gene 5046..6662
/gene="ORF2"
CDS 5046..6662
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55907.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6662..7441
/gene="ORF3"
CDS 6662..7441
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55908.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 aaacaacaac aacgacaatg taaaatcttc aagtgacagc ttgttttcta acatgactgt
61 tacttttaag aaagccctcg gggcgcggtc taagcagccg cccccgggag aaacaaaaca
121 aacactaaga ccaccaaggc cgccgacacc ggaattggtg aagaagatac ccccaccccc
181 ccccaatggc gaggatgaac caaaggtaac gtataaggtg ggagaaggtg tgtctgggct
241 gcccgactta acaaccgtgg cacaacctga cgcacagaac acagcctata gtgtcccccc
301 acttagccag agagaggtcg gcgaagctag agaaccgttg cctggctcca ttctggaaat
361 gtgggatggt gagatctacc actatgggct gtatgttgag cgggggcatg tgctgggagt
421 gcacaaacca cctgctgcaa taagccttgc caaaattgag ttaacaccgc tgtctctcta
481 ctggagagtg gtctacactc cccagtactt gatagctcca gagaccctca agaatttaaa
541 tggagagact ttcccataca cggcctttga caacaactgt tatgccttct gttgttgggt
601 tctagacctc aacgactcct ggcttagcag aagaatggtc caaagaacaa ccggattctt
661 cagaccgtat caggactgga acagaaaacc cttaccaacc atggatgaac caaaaatcaa
721 gaaggccgcg aatgctgttc tgtgtgctct ctcctcactc ttcactaggc ccatcaaaga
781 tgtcattgga aagcttaaac cactaaacat tatgaacata ctggcaactt gtgattggac
841 ttttgcgggc atagtggaat ccatgatcct tcttgctgaa ctctttgggg tgttctggac
901 gcccccagat gtgtctgcaa taattgctcc cttactcggt gactacgaga tgcaaggccc
961 cgaagacctg gccgtggaac ttgtgcccgt ggtaatggga ggaataggtt tggtgttagg
1021 attcaccaag gaaaagatcg gcaagatgct ttcatcagct gcaaccacac tcagggcctg
1081 taaggatcta ggatcttatg ggttggagat actcaaactg gtcatgaagt ggttcttccc
1141 caagaaggag gaggccaacg agttagccat ggtgagggcc attgaggatg cagttctgga
1201 tttggaggca atagaaaaca accacatgac cactctcctt aaggacaaag acgccctggc
1261 cacatacatg aggactcttg acttggaaga agaaaaagca aggaaactat cttccaaatc
1321 ggcgtcacct gacatcgtgg gcacagtaaa cgcattattg gcaagaatag cagccgccag
1381 gtcactggtc cacaaggcta aggaggagct ctcgagcaga cagagacctg ttgttgtaat
1441 gatatcaggt aggccaggta taggaaagac ccatctggcc agagagctag ccaagaaggt
1501 tgcgtcaaca ctgtcaggcg accaaaggat tggactgata cccagaaatg gcgtcgacca
1561 ttgggacgcc tacaaaggag agcgggtggt tctgtgggat gactatggca tgagcaaccc
1621 tatacaggac gcactgaggc tccaagaatt ggctgacacc tgtcctctga ccctaaattg
1681 tgacagaatt gaaaacaaag gaaaagtgtt cgacagtgac gccataatca taacgaccaa
1741 tcttgcaaac ccagcaccat tggattatgt caactttgag gcttgttcca gacgcataga
1801 cttcttggtg tatgcagacg cacctgacat cgagaaggct aagcgtgact tccctggcca
1861 accagatatg tggaaagacc attacagacc agacttctca cacattaaac ttcagctcgc
1921 accacaggga ggctttgata agagtggcaa caccccacat ggcaaaggtg tggttaagtc
1981 tctgacgatt ggttctctga tcgccagggc ttctggcttg ctccatgaga gaatggatga
2041 attcgagctc caaggcccca acttaccaac cttcaatttc gaccgtaaca aagtcgccgc
2101 cttcagacaa ttggcagctg aaaacaaata cggtcttatg gacacactga gggtcggcaa
2161 ccaactgaaa agtgtcaaaa ccctggatga gctgaagcag gctataaaga acatcaccat
2221 caagaagtgc cagatagtgt acaatggatg cacctacacc atggaatctg atgggaggaa
2281 caaggttgtg gttgaaaagg ttcaaaatgc aacagtccaa accaacaatg agcttgcagg
2341 agcactccac cacctgagat ctgcaagaat aaggtattat gtcaaatgtt tccaagaagc
2401 tatttactct atactccaaa ttgctggtgc agccttcgtc accacacgca tcgtgaggcg
2461 catgaacatc tcaaacctct ggtcgaagcc acccgtcgaa gagggtgatg agcctgaaga
2521 caaagggggg tgccccaagc ccagggatga agatgacctc actattgact ccaaagacat
2581 taaagcagaa ggtaagaagg gcaagaacaa atctggccgg ggcaagaaac acacagcttt
2641 ctcatccaag ggcctcagtg atgaagagta cgatgagtac aagagaatca gggaggagag
2701 aaatggcaag tactcaatag aagaatacct ccaggatagg gatagatact atgaagagct
2761 tgccattgct aaggccactg aggaagactt ctgtgaagag gaggaaatca aaattcgcca
2821 gagaatcttc cggcccacca ggaagcagcg gaaagaggaa agagccacgc ttgggctcgt
2881 cacaggatcg gaaatcagaa agaggaaccc agatgatttt aagccaaaag gaaaattgtg
2941 ggctgatgac aacaggagtg tggactacaa tgagaggata gattttgagg ctcccccaag
3001 tgtttggtct aggatagtca actttggtac agggtgggga ttctgggtct ccccaagtct
3061 ctttataact tcaacacatg tcataccaaa aggaatcact gaggcctttg gagttcctat
3121 taaccaaatt caaattcaca aatctggaga gttttgccgc ttgcggtttc caaaaccaat
3181 caggccagac gtgagtggaa tgatcttgga agagggtgcc cctgaaggca ctgttgtttc
3241 cattctcatc aagaggacga caggggaact gatgcctctc gcagtcagaa tgggaactca
3301 tgccacaatg aaaatccaag gtagaacggt gggcggtcaa atgggcatgc ttctcactgg
3361 ctcaaacgcc aaaagcatgg acctaggcac aacaccaggt gactgtgggt gcccatacat
3421 atacaaaagg ggcaatgact tcgtggtcat tggggtgcac actgcagcag cccgtggagg
3481 taacacggtc atatgtgcca cacaggggag tgaaggcgaa gccaccctcg aaggaggtga
3541 caacaagggc acctattgtg gagcccccat cttgggtcct ggcaacgcac caaaattgag
3601 cacaaaaaca aaattctgga gatcttctaa cgcgccgctc ccgccaggca cctatgaacc
3661 agcatacctt ggtggaaaag acccgcgtgt gaagggaggc ccatctctac aacaggttat
3721 gagagaccaa ctcaaacctt ttacagagcc cagagggaag ccaccaaaac caagtgtcct
3781 agaatcagca aagaagacca tcattaatgt tctggaacaa accattgacc cccctgaaaa
3841 gtggtcatat gcccaagctt gtgcatccct cgacaagaca acctccagtg gatacccgca
3901 tcacgtccgg aagaatgact actggagtgg tgaatccttc acggggaaac ttgcagacca
3961 ggcctcaaaa gcaaatctca tgtatgagga aggtaagcac atgcaaccag tttacaccgc
4021 agcactcaaa gacgagctcg tgaaaactga caaaatttat ggcaagatca agaaaagact
4081 cctgtggggc tctgacctat ccaccatgat tcgatgcgcc agggcatttg gtggcctcat
4141 ggacgagctc aaagcaaatt gtatcacact ccctatcaga gttggtatga acatgaatga
4201 agatggtccc ataatatttg aaaagcactc caggtacagg taccactatg atgctgatta
4261 ttcccgctgg gattccacac aacagcgggc agtgctggaa gcggcacttg aaatcatggt
4321 gagattttct gctgagccac agttggcaca aatagtggca gaggacctgc tatcaccaag
4381 tgtggttgat gtgggcgatt tcaaaattac tattaatgaa ggcctaccat ctggcgtgcc
4441 ttgcacttca caatggaatt ctattgccca ctggttactc accctatgtg ccctgtctga
4501 agtgacagga ctaggccctg acatcataca agccaactcc atgtactctt tctatggtga
4561 tgatgagatt gtgagcacag acataaaatt agacccagag aaattgactg caaaactcaa
4621 agaatatggt cttaaaccca cccggcctga caagactgag gggccactgg taattagtga
4681 ggacctgaat gggttgactt tcctccgccg aacagtcacc cgcgatccag cgggttggtt
4741 tggaaagttg gaccaaaact ccatcctcag acagctgtac tggacaaggg gacccaacca
4801 tgaagacccc agtgagacta tgataccaca cgcacagaga cctgtgcagc tcatggcatt
4861 gctaggagaa tcctccctac atggaccctc attttacagc aaggttagca agctggttat
4921 atctgaactt aaagagggag gaatggattt ttatgtgccc agacaagagt caatgttcag
4981 gtggatgagg ttctcagatc taagcacatg ggagggcgat cgcaatctgg ctcccagttt
5041 tgtgaatgaa gatggcgtcg aatgacgccg ctccatctaa tgatggtgct gctggtctcg
5101 taccagaggg caataacgag acccttcccc tagaaccagt tgcgggcgca gccatagccg
5161 cacccgtcac tggccaaaat aatataattg acccctggat tagaacaaat tttgtgcaag
5221 caccaaatgg agagttcaca gtgtcaccca gaaactctcc tggagaaatt ttactaaacc
5281 tagagttggg ccctgatctg aacccttatt tggctcattt gtcaaggatg tataatggat
5341 atgctggtgg agttgaagtc caggttctcc tggcagggaa cgcgttcact gccgggaaga
5401 tcctcttcgc cgctgtcccg ccaaattttc cggtggaatt cttaagccca gcccagatta
5461 caatgctccc acatataata gtagatgtta ggactcttga accaattatg atcccattac
5521 ctgatgttag gaatacattc ttccactata ataatcagcc caacagccgc atgagattag
5581 tggctatgct ctacaccccc cttagatcta atggctcagg tgatgatgtt ttcactgttt
5641 cttgcagggt tttgactagg cctactcctg attttgagtt cacttatcta gtgccaccct
5701 ctgttgaatc taagactaaa cccttttctt tacccattct aaccctttct gagctcacaa
5761 attcgaggtt cccggtcccc atcgattcgc ttttcaccgc ccaaaataat gtgttgcagg
5821 tgcagtgtca aaatggcagg tgcacacttg acggtgagct acaaggcaca acccagttgc
5881 tcccatctgg catctgtgcg ttcaggggac gggtgacagc agaaactgac aatcctgaca
5941 agtggcacat gcaactgcaa aaccttaatg gcacaacata tgacccaact gatgatgtgc
6001 cagccccact gggtacacct gacttcaagg gcgtcgtgtt tgggatggca agccaaagaa
6061 atgtgggtaa cgacgcgccc ggctcaacca ggtcccatga ggcggtgatt tcaacctaca
6121 gccccagatt tgttcctaaa ttaggctctg tcaatttcaa aagcaatgac gatgatttcc
6181 aattgcagcc aacaagattc acaccagtgg gcattaatga tgatggcaac caaccattca
6241 gacaatggga actaccagat tattcagggg tgcttacctt gaatatgaac cttgcccccc
6301 ctgttgctcc aaatttccct ggcgaacaat tactattctt cagatcttct gtgccatgtt
6361 caggaggtta caaccaaggt attatagatt gccttatccc ccaagaatgg atccaacatt
6421 tctaccagga atcagcacct tctcagtcag aagtggccct aatcaggtac gtcaaccccg
6481 acacgggtcg tacactgttt gaggcaaaat tgcataggtc aggctatatc actgtggctc
6541 attctggaga ctatcctctt gttgttccgg ctaatggata ttttagattt gactcttggg
6601 taaatcagtt ttactcactc gccccaatgg gaactgggaa tgggcgaagg agggctcagt
6661 aatggctgga gctttcattg caggattggc gggtgacatg ctcacgtcat ccgtgggctc
6721 cctggtgaac gcaggggcaa acgccatcaa ccaaaagata gactttgaaa acaacaaaca
6781 actccagtct gcttcctttc aacatgataa agagatgctc caagcgcagg tgaacgcaac
6841 caagcagctg caatctgaga tgatagccct aaaacagggg gttttggccg caggcggctt
6901 ttcccccact gatgcagcga ggggggccat cggtgcaccc atgacaaagg tgcttgactg
6961 gtctggcact cgatactggg ctcccaattc cacaaagaca actggttatt cggggcaatt
7021 cacctcttca cctgtgcaca tgcccagccc gagtgtccca caatcaaaac ccgcaaagcc
7081 caagtctcta ggttcttctt cttcttctag tagtgtttac agtatgtcta cccaattaac
7141 ttctctaaca tctggctctt ctagtaatgc ttcttctgct tctacaaaat tgacaaattt
7201 gagctccggc tcttctcaaa acagaacagc agagtgggtg aaccaacaga gaagtctcag
7261 ccctttcatg agtggcgcac tcaatatctc gcatgtcacg ccaccttcaa gtagggcctc
7321 cagttctggg acggtctcaa ccgtgcccaa ggaagttttg gactcctgga catctgcatt
7381 caacacacgc agacagccgc tcttcgcaca cctcagagtg aggggggagt cacgtgttta
7441 gtgaaaagaa ataattggct ataatatgat ttctttaaaa tttaaatttg gctaatttgt
7501 atctttt
//