Typing tool
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Typing tool
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Complete norovirus genomes
| PV750889 | GII.17 | |
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| GII.P17 |
ORF1: 1..5104
ORF2: 5085..6701
ORF3: 6701..7480
LOCUS PV750889 7546 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_13_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750889
VERSION PV750889.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7546)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7546)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7546
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_13_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="10-Feb-2024"
/note="genotype: GII.17"
gene <1..5104
/gene="ORF1"
CDS <1..5104
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XUS55903.1"
/translation="MASNDASVAVAGKNNNNDNVKSSSDSLFSNMTVTFKKALGARSK
QPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVAQP
DAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIG
KLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLS
SKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHL
RSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGG
CPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGL
VTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..994
/gene="ORF1"
/product="p48"
mat_peptide 995..2092
/gene="ORF1"
/product="NTPase"
mat_peptide 2093..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6701
/gene="ORF2"
CDS 5085..6701
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55904.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6701..7480
/gene="ORF3"
CDS 6701..7480
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55905.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 tatggcgtct aacgacgctt ccgttgccgt tgctggcaaa aacaacaaca acgacaatgt
61 aaaatcttca agtgacagct tgttttctaa catgactgtt acttttaaga aagccctcgg
121 ggcgcggtct aagcagccgc ccccgggaga aacaaaacaa acactaagac caccaaggcc
181 gccgacaccg gaattggtga agaagatacc cccacccccc cccaatggcg aggatgaacc
241 aaaggtaacg tataaggtgg gagaaggtgt gtctgggctg cccgacttaa caaccgtggc
301 acaacctgac gcacagaaca cagcctatag tgtcccccca cttagccaga gagaggtcgg
361 cgaagctaga gaaccgttgc ctggctccat tctggaaatg tgggatggtg agatctacca
421 ctatgggctg tatgttgagc gggggcatgt gctgggagtg cacaaaccac ctgctgcaat
481 aagccttgcc aaaattgagt taacaccgct gtctctctac tggagagtgg tctacactcc
541 ccagtacttg atagctccag agaccctcaa gaatttaaat ggagagactt tcccatacac
601 ggcctttgac aacaactgtt atgccttctg ttgttgggtt ctagacctca acgactcctg
661 gcttagcaga agaatggtcc aaagaacaac cggattcttc agaccgtatc aggactggaa
721 cagaaaaccc ttaccaacca tggatgaacc aaaaatcaag aaggccgcga atgctgttct
781 gtgtgctctc tcctcactct tcactaggcc catcaaagat gtcattggaa agcttaaacc
841 actaaacatt atgaacatac tggcaacttg tgattggact tttgcgggca tagtggaatc
901 catgatcctt cttgctgaac tctttggggt gttctggacg cccccagatg tgtctgcaat
961 aattgctccc ttactcggtg actacgagat gcaaggcccc gaagacctgg ccgtggaact
1021 tgtgcccgtg gtaatgggag gaataggttt ggtgttagga ttcaccaagg aaaagatcgg
1081 caagatgctt tcatcagctg caaccacact cagggcctgt aaggatctag gatcttatgg
1141 gttggagata ctcaaactgg tcatgaagtg gttcttcccc aagaaggagg aggccaacga
1201 gttagccatg gtgagggcca ttgaggatgc agttctggat ttggaggcaa tagaaaacaa
1261 ccacatgacc actctcctta aggacaaaga cgccctggcc acatacatga ggactcttga
1321 cttggaagaa gaaaaagcaa ggaaactatc ttccaaatcg gcgtcacctg acatcgtggg
1381 cacagtaaac gcattattgg caagaatagc agccgccagg tcactggtcc acaaggctaa
1441 ggaggagctc tcgagcagac agagacctgt tgttgtaatg atatcaggta ggccaggtat
1501 aggaaagacc catctggcca gagagctagc caagaaggtt gcgtcaacac tgtcaggcga
1561 ccaaaggatt ggactgatac ccagaaatgg cgtcgaccat tgggacgcct acaaaggaga
1621 gcgggtggtt ctgtgggatg actatggcat gagcaaccct atacaggacg cactgaggct
1681 ccaagaattg gctgacacct gtcctctgac cctaaattgt gacagaattg aaaacaaagg
1741 aaaagtgttc gacagtgacg ccataatcat aacgaccaat cttgcaaacc cagcaccatt
1801 ggattatgtc aactttgagg cttgttccag acgcatagac ttcttggtgt atgcagacgc
1861 acctgacatc gagaaggcta agcgtgactt ccctggccaa ccagatatgt ggaaagacca
1921 ttacagacca gacttctcac acattaaact tcagctcgca ccacagggag gctttgataa
1981 gagtggcaac accccacatg gcaaaggtgt ggttaagtct ctgacgattg gttctctgat
2041 cgccagggct tctggcttgc tccatgagag aatggatgaa ttcgagctcc aaggccccaa
2101 cttaccaacc ttcaatttcg accgtaacaa agtcgccgcc ttcagacaat tggcagctga
2161 aaacaaatac ggtcttatgg acacactgag ggtcggcaac caactgaaaa gtgtcaaaac
2221 cctggatgag ctgaagcagg ctataaagaa catcaccatc aagaagtgcc agatagtgta
2281 caatggatgc acctacacca tggaatctga tgggaggaac aaggttgtgg ttgaaaaggt
2341 tcaaaatgca acagtccaaa ccaacaatga gcttgcagga gcactccacc acctgagatc
2401 tgcaagaata aggtattatg tcaaatgttt ccaagaagct atttactcta tactccaaat
2461 tgctggtgca gccttcgtca ccacacgcat cgtgaggcgc atgaacatct caaacctctg
2521 gtcgaagcca cccgtcgaag agggtgatga gcctgaagac aaaggggggt gccccaagcc
2581 cagggatgaa gatgacctca ctattgactc caaagacatt aaagcagaag gtaagaaggg
2641 caagaacaaa tctggccggg gcaagaaaca cacagctttc tcatccaagg gcctcagtga
2701 tgaagagtac gatgagtaca agagaatcag ggaggagaga aatggcaagt actcaataga
2761 agaatacctc caggataggg atagatacta tgaagagctt gccattgcta aggccactga
2821 ggaagacttc tgtgaagagg aggaaatcaa aattcgccag agaatcttcc ggcccaccag
2881 gaagcagcgg aaagaggaaa gagccacgct tgggctcgtc acaggatcgg aaatcagaaa
2941 gaggaaccca gatgatttta agccaaaagg aaaattgtgg gctgatgaca acaggagtgt
3001 ggactacaat gagaggatag attttgaggc tcccccaagt gtttggtcta ggatagtcaa
3061 ctttggtaca gggtggggat tctgggtctc cccaagtctc tttataactt caacacatgt
3121 cataccaaaa ggaatcactg aggcctttgg agttcctatt aaccaaattc aaattcacaa
3181 atctggagag ttttgccgct tgcggtttcc aaaaccaatc aggccagacg tgagtggaat
3241 gatcttggaa gagggtgccc ctgaaggcac tgttgtttcc attctcatca agaggacgac
3301 aggggaactg atgcctctcg cagtcagaat gggaactcat gccacaatga aaatccaagg
3361 tagaacggtg ggcggtcaaa tgggcatgct tctcactggc tcaaacgcca aaagcatgga
3421 cctaggcaca acaccaggtg actgtgggtg cccatacata tacaaaaggg gcaatgactt
3481 cgtggtcatt ggggtgcaca ctgcagcagc ccgtggaggt aacacggtca tatgtgccac
3541 acaggggagt gaaggcgaag ccaccctcga aggaggtgac aacaagggca cctattgtgg
3601 agcccccatc ttgggtcctg gcaacgcacc aaaattgagc acaaaaacaa aattctggag
3661 atcttctaac gcgccgctcc cgccaggcac ctatgaacca gcataccttg gtggaaaaga
3721 cccgcgtgtg aagggaggcc catctctaca acaggttatg agagaccaac tcaaaccttt
3781 tacagagccc agagggaagc caccaaaacc aagtgtccta gaatcagcaa agaagaccat
3841 cattaatgtt ctggaacaaa ccattgaccc ccctgaaaag tggtcatatg cccaagcttg
3901 tgcatccctc gacaagacaa cctccagtgg atacccgcat cacgtccgga agaatgacta
3961 ctggagtggt gaatccttca cggggaaact tgcagaccag gcctcaaaag caaatctcat
4021 gtatgaggaa ggtaagcaca tgcaaccagt ttacaccgca gcactcaaag acgagctcgt
4081 gaaaactgac aaaatttatg gcaagatcaa gaaaagactc ctgtggggct ctgacctatc
4141 caccatgatt cgatgcgcca gggcatttgg tggcctcatg gacgagctca aagcaaattg
4201 tatcacactc cctatcagag ttggtatgaa catgaatgaa gatggtccca taatatttga
4261 aaagcactcc aggtacaggt accactatga tgctgattat tcccgctggg attccacaca
4321 acagcgggca gtgctggaag cggcacttga aatcatggtg agattttctg ctgagccaca
4381 gttggcacaa atagtggcag aggacctgct atcaccaagt gtggttgatg tgggcgattt
4441 caaaattact attaatgaag gcctaccatc tggcgtgcct tgcacttcac aatggaattc
4501 tattgcccac tggttactca ccctatgtgc cctgtctgaa gtgacaggac taggccctga
4561 catcatacaa gccaactcca tgtactcttt ctatggtgat gatgagattg tgagcacaga
4621 cataaaatta gacccagaga aattgactgc aaaactcaaa gaatatggtc ttaaacccac
4681 ccggcctgac aagactgagg ggccactggt aattagtgag gacctgaatg ggttgacttt
4741 cctccgccga acagtcaccc gcgatccagc gggttggttt ggaaagttgg accaaaactc
4801 catcctcaga cagctgtact ggacaagggg acccaaccat gaagacccca gtgagactat
4861 gataccacac gcacagagac ctgtgcagct catggcattg ctaggagaat cctccctaca
4921 tggaccctca ttttacagca aggttagcaa gctggttata tctgaactta aagagggagg
4981 aatggatttt tatgtgccca gacaagagtc aatgttcagg tggatgaggt tctcagatct
5041 aagcacatgg gagggcgatc gcaatctggc tcccagtttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctaat gatggtgctg ctggtctcgt accagagggc aataacgaga
5161 cccttcccct agaaccagtt gcgggcgcag ccatagccgc acccgtcact ggccaaaata
5221 atataattga cccctggatt agaacaaatt ttgtgcaagc accaaatgga gagttcacag
5281 tgtcacccag aaactctcct ggagaaattt tactaaacct agagttgggc cctgatctga
5341 acccttattt ggctcatttg tcaaggatgt ataatggata tgctggtgga gttgaagtcc
5401 aggttctcct ggcagggaac gcgttcactg ccgggaagat cctcttcgcc gctgtcccgc
5461 caaattttcc ggtggaattc ttaagcccag cccagattac aatgctccca catataatag
5521 tagatgttag gactcttgaa ccaattatga tcccattacc tgatgttagg aatacattct
5581 tccactataa taatcagccc aacagccgca tgagattagt ggctatgctc tacacccccc
5641 ttagatctaa tggctcaggt gatgatgttt tcactgtttc ttgcagggtt ttgactaggc
5701 ctactcctga ttttgagttc acttatctag tgccaccctc tgttgaatct aagactaaac
5761 ccttttcttt acccattcta accctttctg agctcacaaa ttcgaggttc ccggtcccca
5821 tcgattcgct tttcaccgcc caaaataatg tgttgcaggt gcagtgtcaa aatggcaggt
5881 gcacacttga cggtgagcta caaggcacaa cccagttgct cccatctggc atctgtgcgt
5941 tcaggggacg ggtgacagca gaaactgaca atcctgacaa gtggcacatg caactgcaaa
6001 accttaatgg cacaacatat gacccaactg atgatgtgcc agccccactg ggtacacctg
6061 acttcaaggg cgtcgtgttt gggatggcaa gccaaagaaa tgtgggtaac gacgcgcccg
6121 gctcaaccag gtcccatgag gcggtgattt caacctacag ccccagattt gttcctaaat
6181 taggctctgt caatttcaaa agcaatgacg atgatttcca attgcagcca acaagattca
6241 caccagtggg cattaatgat gatggcaacc aaccattcag acaatgggaa ctaccagatt
6301 attcaggggt gcttaccttg aatatgaacc ttgccccccc tgttgctcca aatttccctg
6361 gcgaacaatt actattcttc agatcttctg tgccatgttc aggaggttac aaccaaggta
6421 ttatagattg ccttatcccc caagaatgga tccaacattt ctaccaggaa tcagcacctt
6481 ctcagtcaga agtggcccta atcaggtacg tcaaccccga cacgggtcgt acactgtttg
6541 aggcaaaatt gcataggtca ggctatatca ctgtggctca ttctggagac tatcctcttg
6601 ttgttccggc taatggatat tttagatttg actcttgggt aaatcagttt tactcactcg
6661 ccccaatggg aactgggaat gggcgaagga gggctcagta atggctggag ctttcattgc
6721 aggattggcg ggtgacatgc tcacgtcatc cgtgggctcc ctggtgaacg caggggcaaa
6781 cgccatcaac caaaagatag actttgaaaa caacaaacaa ctccagtctg cttcctttca
6841 acatgataaa gagatgctcc aagcgcaggt gaacgcaacc aagcagctgc aatctgagat
6901 gatagcccta aaacaggggg ttttggccgc aggcggcttt tcccccactg atgcagcgag
6961 gggggccatc ggtgcaccca tgacaaaggt gcttgactgg tctggcactc gatactgggc
7021 tcccaattcc acaaagacaa ctggttattc ggggcaattc acctcttcac ctgtgcacat
7081 gcccagcccg agtgtcccac aatcaaaacc cgcaaagccc aagtctctag gttcttcttc
7141 ttcttctagt agtgtttaca gtatgtctac ccaattaact tctctaacat ctggctcttc
7201 tagtaatgct tcttctgctt ctacaaaatt gacaaatttg agctccggct cttctcaaaa
7261 cagaacagca gagtgggtga accaacagag aagtctcagc cctttcatga gtggcgcact
7321 caatatctcg catgtcacgc caccttcaag tagggcctcc agttctggga cggtctcaac
7381 cgtgcccaag gaagttttgg actcctggac atctgcattc aacacacgca gacagccgct
7441 cttcgcacac ctcagagtga ggggggagtc acgtgtttag tgaaaagaaa taattggcta
7501 taatatgatt tctttaaaat ttaaatttgg ctaatttgta tctttt
//