Typing tool
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Typing tool
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Complete norovirus genomes
| PV750887 | GII.17 | |
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| GII.P17 |
ORF1: 1..5108
ORF2: 5089..6705
ORF3: 6705..7484
LOCUS PV750887 7550 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_11_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750887
VERSION PV750887.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7550)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7550)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7550
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_11_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="10-Feb-2024"
/note="genotype: GII.17"
gene <1..5108
/gene="ORF1"
CDS <1..5108
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUS55897.1"
/translation="KMASNDASVAVAGKNNNNDNVKSSSDSLFSNMTVTFKKALGARS
KQPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVMYKVGEGVSGLPDLTTVAQ
PDAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAA
ISLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVI
GKLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKL
SSKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAR
ELAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELAD
TCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDI
EKAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIA
RASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVK
TLDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHH
LRSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKG
GCPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREER
NGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLG
LVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWV
SPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAP
EGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTP
GDCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPI
LGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFT
EPRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPYHVRKND
YWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGS
DLSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSR
WDSTQQRAVLEAALEIIVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVP
CTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAK
LKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTR
GPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPR
QESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..998
/gene="ORF1"
/product="p48"
mat_peptide 999..2096
/gene="ORF1"
/product="NTPase"
mat_peptide 2097..2633
/gene="ORF1"
/product="p22"
mat_peptide 2634..3032
/gene="ORF1"
/product="VPg"
mat_peptide 3033..3575
/gene="ORF1"
/product="Pro"
mat_peptide 3576..5105
/gene="ORF1"
/product="RdRp"
gene 5089..6705
/gene="ORF2"
CDS 5089..6705
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55898.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6705..7484
/gene="ORF3"
CDS 6705..7484
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55899.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVHSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 tgaagatggc gtctaacgac gcttccgttg ccgttgctgg caaaaacaac aacaacgaca
61 atgtaaaatc ttcaagtgac agcttgtttt ctaacatgac tgttactttt aagaaagccc
121 tcggggcgcg gtctaagcag ccgcccccgg gagaaacaaa acaaacacta agaccaccaa
181 ggccgccgac accggaattg gtgaagaaga tacccccacc cccccccaat ggcgaggatg
241 aaccaaaggt aatgtataag gtgggagaag gtgtgtctgg gctgcccgac ttaacaactg
301 tggcacaacc tgacgcacag aacacagcct atagtgtccc cccacttagc cagagagagg
361 tcggcgaagc tagagaaccg ttgcctggct ccattctgga aatgtgggat ggtgagatct
421 accactatgg gctgtatgtt gagcgggggc atgtgctggg agtgcacaaa ccacctgctg
481 caataagcct tgccaaaatt gagttaacac cgctgtctct ctactggaga gtggtctaca
541 ctccccagta cttgatagct ccagagaccc tcaagaattt aaatggagag actttcccat
601 acacggcctt tgacaacaac tgttatgcct tctgttgttg ggttctagac ctcaacgact
661 cctggcttag cagaagaatg gtccaaagaa caaccggatt cttcagaccg tatcaggact
721 ggaacagaaa acccttacca accatggatg aaccaaaaat caagaaggcc gcgaatgctg
781 ttctgtgtgc tctctcctca ctcttcacta ggcccatcaa agatgtcatt ggaaagctta
841 aaccactaaa cattatgaac atactggcaa cttgtgattg gacttttgcg ggcatagtgg
901 aatccatgat ccttcttgct gaactctttg gggtgttctg gacgccccca gatgtgtctg
961 caataattgc tcccttactc ggtgactacg agatgcaagg ccccgaagac ctggccgtgg
1021 aacttgtgcc cgtggtaatg ggaggaatag gtttggtgtt aggattcacc aaggaaaaga
1081 tcggcaagat gctttcatca gctgcaacca cactcagggc ctgtaaggat ctaggatctt
1141 atgggttgga gatactcaaa ctggtcatga agtggttctt ccccaagaag gaggaggcca
1201 acgagttagc catggtgagg gccattgagg atgcagttct ggatttggag gcaatagaaa
1261 acaaccacat gaccactctc cttaaggaca aagacgccct ggccacatac atgaggactc
1321 ttgacttgga agaagaaaaa gcaaggaaac tatcttccaa atcggcgtca cctgacatcg
1381 tgggcacagt aaacgcatta ttggcaagaa tagcagccgc caggtcactg gtccacaagg
1441 ctaaggagga gctctcgagc agacagagac ctgttgttgt aatgatatca ggtaggccag
1501 gtataggaaa gacccatctg gccagagagc tagccaagaa ggttgcgtca acactgtcag
1561 gcgaccaaag gattggactg atacccagaa atggcgtcga ccattgggac gcctacaaag
1621 gagagcgggt ggttctgtgg gatgactatg gcatgagcaa ccctatacag gacgcactga
1681 ggctccaaga attggctgac acctgtcctc tgaccctaaa ttgtgacaga attgaaaaca
1741 aaggaaaagt gttcgacagt gacgccataa tcataacgac caaccttgca aacccagcac
1801 cattggatta tgttaacttt gaggcttgtt ccagacgcat agacttcttg gtgtatgcag
1861 acgcacctga catcgagaag gctaagcgtg acttccctgg ccaaccagat atgtggaaag
1921 accattacag accagacttc tcacacatta aacttcagct cgcaccacag ggaggctttg
1981 ataagagtgg caacacccca catggcaaag gtgtggttaa gtctctgacg attggttctc
2041 tgatcgccag ggcttctggc ttgctccatg agagaatgga tgaattcgag ctccaaggcc
2101 ccaacttacc aaccttcaat ttcgaccgta acaaagtcgc cgccttcaga caattggcag
2161 ctgaaaacaa atacggtctt atggacacac tgagggtcgg caaccaactg aaaagtgtca
2221 aaaccctgga tgagctgaag caggctataa agaacatcac catcaagaag tgccagatag
2281 tgtacaatgg atgcacctac accatggaat ctgatgggag gaacaaggtt gtggttgaaa
2341 aggttcaaaa tgcaacagtc caaaccaaca atgaacttgc aggagcactc caccacctga
2401 gatctgcaag aataaggtat tatgtcaaat gtttccaaga agctatttac tctatactcc
2461 aaattgctgg tgcagccttc gtcaccacac gcatcgtgag gcgcatgaac atctcaaacc
2521 tctggtcgaa gccacccgtc gaagagggtg atgagcctga agacaaaggg gggtgcccca
2581 agcccaggga tgaagatgac ctcactattg actccaaaga cattaaagca gaaggtaaga
2641 agggcaagaa caaatctggc cggggcaaga aacacacagc tttctcatcc aagggcctca
2701 gtgatgaaga gtacgatgag tacaagagaa tcagggagga gagaaatggc aagtactcaa
2761 tagaagaata cctccaggat agggatagat actatgaaga gcttgccatt gctaaggcca
2821 ctgaggaaga cttctgtgaa gaggaagaaa tcaaaattcg ccagagaatc ttccggccca
2881 ccaggaagca gcgaaaagag gaaagagcca cgcttgggct cgtcacagga tcggaaatca
2941 gaaagaggaa cccagatgat tttaagccaa aaggaaaatt gtgggctgat gacaacagga
3001 gtgtggacta caatgagagg atagattttg aggctccccc aagtgtttgg tctaggatag
3061 tcaactttgg tacagggtgg ggattctggg tctccccaag tctctttata acttcaacac
3121 atgtcatacc aaaaggaatc actgaggcct ttggagttcc cattaaccaa attcaaattc
3181 acaaatctgg agagttttgc cgcttgcggt ttccaaaacc aatcaggcca gacgtgagtg
3241 gaatgatctt ggaagagggt gcccctgaag gcactgttgt ttccattctc atcaagagga
3301 cgacagggga actgatgcct ctcgcagtca gaatgggaac tcatgccaca atgaaaatcc
3361 aaggtagaac ggtgggcggt caaatgggca tgcttctcac tggctcaaac gccaaaagca
3421 tggacctagg cacaacacca ggtgactgtg ggtgcccata catatacaaa aggggcaatg
3481 acttcgtggt cattggggtg cacactgcag cagcccgtgg aggtaacacg gtcatatgtg
3541 ccacacaggg gagtgaaggc gaagccaccc tcgaaggagg tgacaacaag ggcacctatt
3601 gtggagcccc catcttgggt cctggcaacg caccaaaatt gagcacaaaa acaaaattct
3661 ggagatcttc taacgcgccg ctcccgccag gcacctatga accagcatac cttggtggaa
3721 aagacccgcg tgtgaaggga ggcccatctc tacaacaggt tatgagagac caactcaaac
3781 cttttacaga gcccagaggg aagccaccaa aaccaagcgt cctagaatca gcaaagaaga
3841 ccatcattaa tgttctggaa caaaccattg acccacctga aaagtggtca tatgcccaag
3901 cttgtgcatc cctcgacaag acaacctcca gtggataccc gtatcacgtc cggaagaatg
3961 actactggag tggtgaatcc ttcacgggga aacttgcaga ccaggcctca aaagcaaatc
4021 tcatgtatga ggaaggtaag cacatgcaac cagtttacac cgcagcactc aaagacgagc
4081 tcgtgaaaac tgacaaaatt tatggcaaga tcaagaaaag actcctgtgg ggctctgacc
4141 tatccaccat gattcgatgc gccagggcat ttggtggcct catggacgag ctcaaagcaa
4201 attgtatcac actccctatc agagttggta tgaacatgaa tgaagatggt cccataatat
4261 ttgaaaagca ctccaggtac aggtaccact atgatgctga ttattcccgc tgggattcca
4321 cacaacagcg ggcagtgctg gaagcggcac ttgaaatcat agtgagattt tctgctgagc
4381 cacagttggc acaaatagtg gcagaggacc tgctatcacc aagtgtggtt gatgtgggcg
4441 atttcaaaat tactattaat gaaggcctac catctggcgt gccttgcact tcacaatgga
4501 attctattgc ccactggtta ctcaccctat gtgccctgtc tgaagtgaca ggactaggcc
4561 ctgacatcat acaagccaac tccatgtact ctttctatgg tgatgatgag attgtgagca
4621 cagacataaa attagaccca gagaaattga ctgcaaaact caaagaatat ggtcttaaac
4681 ccacccggcc tgacaagact gaggggccac tggtaattag tgaggacctg aatgggttga
4741 ctttcctccg ccgaacagtc acccgcgatc cagcgggttg gtttggaaag ttggaccaaa
4801 actccatcct cagacagctg tactggacaa ggggacccaa ccatgaagac cccagtgaga
4861 ctatgatacc acacgcacag agacctgtgc agctcatggc attgctagga gaatcctccc
4921 tacatggacc ctcattttac agcaaggtta gcaagctggt tatatctgaa cttaaagagg
4981 gaggaatgga tttttatgtg cccagacaag agtcaatgtt caggtggatg aggttctcag
5041 atctaagcac atgggagggc gatcgcaatc tggctcccag ttttgtgaat gaagatggcg
5101 tcgaatgacg ccgctccatc taatgatggt gctgctggtc tcgtaccaga gggtaataac
5161 gagacccttc ccctagaacc agttgcgggc gcagccatag ccgcacccgt cactggccaa
5221 aataatataa ttgacccctg gattagaaca aattttgtgc aagcaccaaa tggagagttc
5281 acagtgtcac ccagaaactc tcctggagaa attttactaa acctagagtt gggccctgat
5341 ctgaaccctt atttggctca tttgtcaagg atgtataatg gatatgctgg tggagttgaa
5401 gtccaggttc tcctggcagg gaacgcgttc actgccggga agatcctctt cgccgctgtc
5461 ccgccaaatt ttccggtgga attcttaagc ccagcccaga ttacaatgct cccacatata
5521 atagtagatg ttaggactct tgaaccaatt atgatcccat tacctgatgt taggaataca
5581 ttcttccact ataataatca gcccaacagc cgcatgagat tagtggctat gctctacacc
5641 ccccttagat ctaatggctc aggtgatgat gttttcactg tttcttgcag ggttttgact
5701 aggcctactc ctgattttga gttcacttat ctagtgccac cctctgttga atctaagact
5761 aaaccctttt ctttacccat tctaaccctt tctgagctca caaattcgag gttcccggtc
5821 cccatcgatt cgcttttcac cgcccaaaat aatgtgttgc aggtgcagtg tcaaaatggc
5881 aggtgcacac ttgacggtga gctacaaggc acaacccagt tgctcccatc tggcatctgt
5941 gcgttcaggg gacgggtgac agcagaaact gacaatcctg acaagtggca catgcaactg
6001 caaaacctta atggcacaac atatgaccca actgatgatg tgccagcccc actgggtaca
6061 cctgacttca agggcgtcgt gtttgggatg gcaagccaaa gaaatgtggg taacgacgcg
6121 cccggctcaa ccaggtccca tgaggcggtg atttcaacct acagccccag atttgttcct
6181 aaattaggct ctgtcaattt caaaagcaat gacgatgatt tccaattgca gccaacaaga
6241 ttcacaccag tgggcattaa tgatgatggc aaccaaccat tcagacaatg ggaactacca
6301 gattattcag gggtgcttac cttgaatatg aaccttgccc cccctgttgc tccaaatttc
6361 cctggcgaac aattactatt cttcagatct tctgtgccat gttcaggagg ttacaaccaa
6421 ggtattatag attgccttat cccccaagaa tggatccaac atttctacca ggaatcagca
6481 ccttctcagt cagaagtggc cctaatcagg tacgtcaacc ccgatacggg tcgtacactg
6541 tttgaggcaa aattgcatag gtcaggctat atcactgtgg ctcattctgg agactatcct
6601 cttgttgttc cggctaatgg atactttaga tttgactctt gggtaaatca gttttactca
6661 ctcgccccaa tgggaactgg gaatgggcga aggagggctc agtaatggct ggagctttca
6721 ttgcaggatt ggcgggtgac atgctcacgt catccgtggg ctccctggtg aacgcagggg
6781 caaacgccat caaccaaaag atagactttg aaaacaacaa acaactccag tctgcttcct
6841 ttcaacatga taaagagatg ctccaagcgc aggtgaacgc aaccaagcag ctgcaatctg
6901 agatgatagc cctaaaacag ggggttttgg ccgcaggcgg cttttccccc actgatgcag
6961 cgaggggggc catcggtgca cccatgacaa aggtgcttga ctggtctggc actcgatact
7021 gggctcccaa ttccacaaag acaactggtt attcggggca attcacctct tcacctgtgc
7081 acatgcccag cccgagtgtc ccacaatcaa aacccgcaaa gcccaagtct ctaggttctt
7141 cttcttcttc tagtagtgtt cacagtatgt ctacccaatt aacttctcta acatctggct
7201 cttctagtaa tgcttcttct gcttctacaa aattgacaaa tttgagctcc ggctcttctc
7261 aaaacagaac agcagagtgg gtgaaccaac agagaagtct cagccctttc atgagtggcg
7321 cactcaatat ctcgcatgtc acgccacctt caagtagggc ctccagttct gggacggtct
7381 caaccgtgcc caaggaagtt ttggactcct ggacatctgc attcaacaca cgcagacagc
7441 cgctcttcgc acacctcaga gtgagggggg agtcacgtgt ttagtgaaaa gaaataattg
7501 gctataatat gatttcttta aaatttaaat ttggctaatt tgtatctttt
//