Typing tool
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Typing tool
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Complete norovirus genomes
| PV750881 | GII.17 | |
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| GII.P17 |
ORF1: 1..5105
ORF2: 5086..6702
ORF3: 6702..7481
LOCUS PV750881 7547 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O1_Patient_1_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750881
VERSION PV750881.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7547)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7547)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7547
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O1_Patient_1_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="07-Feb-2024"
/note="genotype: GII.17"
gene <1..5105
/gene="ORF1"
CDS <1..5105
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUS55879.1"
/translation="MASNDASVAVAGKNNNNDNVKSSSDSLFSNMTVTFKKALGARSK
QPPPGETKQTLRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVAQP
DAQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAI
SLAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGETFPYTAFDNNCYAFCCWVLDLND
SWLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIG
KLKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPE
DLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFF
PKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLS
SKSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARE
LAKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADT
CPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIE
KAKRDFPGQPDMWKDHYRPDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIAR
ASGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKT
LDELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHL
RSARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGG
CPKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERN
GKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGL
VTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVS
PSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPE
GTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPG
DCGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPIL
GPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTE
PRGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDY
WSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSD
LSTMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRW
DSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKL
KEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRG
PNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQ
ESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2630
/gene="ORF1"
/product="p22"
mat_peptide 2631..3029
/gene="ORF1"
/product="VPg"
mat_peptide 3030..3572
/gene="ORF1"
/product="Pro"
mat_peptide 3573..5102
/gene="ORF1"
/product="RdRp"
gene 5086..6702
/gene="ORF2"
CDS 5086..6702
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55880.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6702..7481
/gene="ORF3"
CDS 6702..7481
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55881.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQLT
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 agatggcgtc taacgacgct tccgttgccg ttgctggcaa aaacaacaac aacgacaatg
61 taaaatcttc aagtgacagc ttgttttcta acatgactgt tacttttaag aaagccctcg
121 gggcgcggtc taagcagccg cccccgggag aaacaaaaca aacactaaga ccaccaaggc
181 cgccgacacc ggaattggtg aagaagatac ccccaccccc ccccaatggc gaggatgaac
241 caaaggtaac gtataaggtg ggagaaggtg tgtctgggct gcccgactta acaaccgtgg
301 cacaacctga cgcacagaac acagcctata gtgtcccccc acttagccag agagaggtcg
361 gcgaagctag agaaccgttg cctggctcca ttctggaaat gtgggatggt gagatctacc
421 actatgggct gtatgttgag cgggggcatg tgctgggagt gcacaaacca cctgctgcaa
481 taagccttgc caaaattgag ttaacaccgc tgtctctcta ctggagagtg gtctacactc
541 cccagtactt gatagctcca gagaccctca agaatttaaa tggagagact ttcccataca
601 cggcctttga caacaactgt tatgccttct gttgttgggt tctagacctc aacgactcct
661 ggcttagcag aagaatggtc caaagaacaa ccggattctt cagaccgtat caggactgga
721 acagaaaacc cttaccaacc atggatgaac caaaaatcaa gaaggccgcg aatgctgttc
781 tgtgtgctct ctcctcactc ttcactaggc ccatcaaaga tgtcattgga aagcttaaac
841 cactaaacat tatgaacata ctggcaactt gtgattggac ttttgcgggc atagtggaat
901 ccatgatcct tcttgctgaa ctctttgggg tgttctggac gcccccagat gtgtctgcaa
961 taattgctcc cttactcggt gactacgaga tgcaaggccc cgaagacctg gccgtggaac
1021 ttgtgcccgt ggtaatggga ggaataggtt tggtgttagg attcaccaag gaaaagatcg
1081 gcaagatgct ttcatcagct gcaaccacac tcagggcctg taaggatcta ggatcttatg
1141 ggttggagat actcaaactg gtcatgaagt ggttcttccc caagaaggag gaggccaacg
1201 agttagccat ggtgagggcc attgaggatg cagttctgga tttggaggca atagaaaaca
1261 accacatgac cactctcctt aaggacaaag acgccctggc cacatacatg aggactcttg
1321 acttggaaga agaaaaagca aggaaactat cttccaaatc ggcgtcacct gacatcgtgg
1381 gcacagtaaa cgcattattg gcaagaatag cagccgccag gtcactggtc cacaaggcta
1441 aggaggagct ctcgagcaga cagagacctg ttgttgtaat gatatcaggt aggccaggta
1501 taggaaagac ccatctggcc agagagctag ccaagaaggt tgcgtcaaca ctgtcaggcg
1561 accaaaggat tggactgata cccagaaatg gcgtcgacca ttgggacgcc tacaaaggag
1621 agcgggtggt tctgtgggat gactatggca tgagcaaccc tatacaggac gcactgaggc
1681 tccaagaatt ggctgacacc tgtcctctga ccctaaattg tgacagaatt gaaaacaaag
1741 gaaaagtgtt cgacagtgac gccataatca taacgaccaa tcttgcaaac ccagcaccat
1801 tggattatgt caactttgag gcttgttcca gacgcataga cttcttggtg tatgcagacg
1861 cacctgacat cgagaaggct aagcgtgact tccctggcca accagatatg tggaaagacc
1921 attacagacc agacttctca cacattaaac ttcagctcgc accacaggga ggctttgata
1981 agagtggcaa caccccacat ggcaaaggtg tggttaagtc tctgacgatt ggttctctga
2041 tcgccagggc ttctggcttg ctccatgaga gaatggatga attcgagctc caaggcccca
2101 acttaccaac cttcaatttc gaccgtaaca aagtcgccgc cttcagacaa ttggcagctg
2161 aaaacaaata cggtcttatg gacacactga gggtcggcaa ccaactgaaa agtgtcaaaa
2221 ccctggatga gctgaagcag gctataaaga acatcaccat caagaagtgc cagatagtgt
2281 acaatggatg cacctacacc atggaatctg atgggaggaa caaggttgtg gttgaaaagg
2341 ttcaaaatgc aacagtccaa accaacaatg agcttgcagg agcactccac cacctgagat
2401 ctgcaagaat aaggtattat gtcaaatgtt tccaagaagc tatttactct atactccaaa
2461 ttgctggtgc agccttcgtc accacacgca tcgtgaggcg catgaacatc tcaaacctct
2521 ggtcgaagcc acccgtcgaa gagggtgatg agcctgaaga caaagggggg tgccccaagc
2581 ccagggatga agatgacctc actattgact ccaaagacat taaagcagaa ggtaagaagg
2641 gcaagaacaa atctggccgg ggcaagaaac acacagcttt ctcatccaag ggcctcagtg
2701 atgaagagta cgatgagtac aagagaatca gggaggagag aaatggcaag tactcaatag
2761 aagaatacct ccaggatagg gacagatact atgaagagct tgccattgct aaggccactg
2821 aggaagactt ctgtgaagag gaggaaatca aaattcgcca gagaatcttc cggcccacca
2881 ggaagcagcg gaaagaggaa agagccacgc ttgggctcgt cacaggatcg gaaatcagaa
2941 agaggaaccc agatgatttt aagccaaaag gaaaattgtg ggctgatgac aacaggagtg
3001 tggactacaa tgagaggata gattttgagg ctcccccaag tgtttggtct aggatagtca
3061 actttggtac agggtgggga ttctgggtct ccccaagtct ctttataact tcaacacatg
3121 tcataccaaa aggaatcact gaggcctttg gagttcctat taaccaaatt caaattcaca
3181 aatctggaga gttttgccgc ttgcggtttc caaaaccaat caggccagac gtgagtggaa
3241 tgatcttgga agagggtgcc cctgaaggca ctgttgtttc cattctcatc aagaggacga
3301 caggggaact gatgcctctc gcagtcagaa tgggaactca tgccacaatg aaaatccaag
3361 gtagaacggt gggcggtcaa atgggcatgc ttctcactgg ctcaaacgcc aaaagcatgg
3421 acctaggcac aacaccaggt gactgtgggt gcccatacat atacaaaagg ggcaatgact
3481 tcgtggtcat tggggtgcac actgcagcag cccgtggagg taacacggtc atatgtgcca
3541 cacaggggag tgaaggcgaa gccaccctcg aaggaggtga caacaagggc acctattgtg
3601 gagcccccat cttgggtcct ggcaacgcac caaaattgag cacaaaaaca aaattctgga
3661 gatcttctaa cgcgccgctc ccgccaggca cctatgaacc agcatacctt ggtggaaaag
3721 acccgcgtgt gaagggaggc ccatctctac aacaggttat gagagaccaa ctcaaacctt
3781 ttacagagcc cagagggaag ccaccaaaac caagtgtcct agaatcagca aagaagacca
3841 tcattaatgt tctggaacaa accattgacc cccctgaaaa gtggtcatat gcccaagctt
3901 gtgcatccct cgacaagaca acctccagtg gatacccgca tcacgtccgg aagaatgact
3961 actggagtgg tgaatccttc acggggaaac ttgcagacca ggcctcaaaa gcaaatctca
4021 tgtatgagga aggtaagcac atgcaaccag tttacaccgc agcactcaaa gacgagctcg
4081 tgaaaactga caaaatttat ggcaagatca agaaaagact cctgtggggc tctgacctat
4141 ccaccatgat tcgatgcgcc agggcatttg gtggcctcat ggacgagctc aaagcaaatt
4201 gtatcacact ccctatcaga gttggtatga acatgaatga agatggtccc ataatatttg
4261 aaaagcactc caggtacagg taccactatg atgctgatta ttcccgctgg gattccacac
4321 aacagcgggc agtgctggaa gcggcacttg aaatcatggt gagattttct gctgagccac
4381 agttggcaca aatagtggca gaggacctgc tatcaccaag tgtggttgat gtgggcgatt
4441 tcaaaattac tattaatgaa ggcctaccat ctggcgtgcc ttgcacttca caatggaatt
4501 ctattgccca ctggttactc accctatgtg ccctgtctga agtgacagga ctaggccctg
4561 acatcataca agccaactcc atgtactctt tctatggtga tgatgagatt gtgagcacag
4621 acataaaatt agacccagag aaattgactg caaaactcaa agaatatggt cttaaaccca
4681 cccggcctga caagactgag gggccactgg taattagtga ggacctgaat gggttgactt
4741 tcctccgccg aacagtcacc cgcgatccag cgggttggtt tggaaagttg gaccaaaact
4801 ccatcctcag acagctgtac tggacaaggg gacccaacca tgaagacccc agtgagacta
4861 tgataccaca cgcacagaga cctgtgcagc tcatggcatt gctaggagaa tcctccctac
4921 atggaccctc attttacagc aaggttagca agctggttat atctgaactt aaagagggag
4981 gaatggattt ttatgtgccc agacaagagt caatgttcag gtggatgagg ttctcagatc
5041 taagcacatg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg
5101 aatgacgccg ctccatctaa tgatggtgct gctggtctcg taccagaggg caataacgag
5161 acccttcccc tagaaccagt tgcgggcgca gccatagccg cacccgtcac tggccaaaat
5221 aatataattg acccctggat tagaacaaat tttgtgcaag caccaaatgg agagttcaca
5281 gtgtcaccca gaaactctcc tggagaaatt ttactaaacc tagagttggg ccctgatctg
5341 aacccttatt tggctcattt gtcaaggatg tataatggat atgctggtgg agttgaagtc
5401 caggttctcc tggcagggaa cgcgttcact gccgggaaga tcctcttcgc cgctgtcccg
5461 ccaaattttc cggtggaatt cttaagccca gcccagatta caatgctccc acatataata
5521 gtagatgtta ggactcttga accaattatg atcccattac ctgatgttag gaatacattc
5581 ttccactata ataatcagcc caacagccgc atgagattag tggctatgct ctacaccccc
5641 cttagatcta atggctcagg tgatgatgtt ttcactgttt cttgcagggt tttgactagg
5701 cctactcctg attttgagtt cacttatcta gtgccaccct ctgttgaatc taagactaaa
5761 cccttttctt tacccattct aaccctttct gagctcacaa attcgaggtt cccggtcccc
5821 atcgattcgc ttttcaccgc ccaaaataat gtgttgcagg tgcagtgtca aaatggcagg
5881 tgcacacttg acggtgagct acaaggcaca acccagttgc tcccatctgg catctgtgcg
5941 ttcaggggac gggtgacagc agaaactgac aatcctgaca agtggcacat gcaactgcaa
6001 aaccttaatg gcacaacata tgacccaact gatgatgtgc cagccccact gggtacacct
6061 gacttcaagg gcgtcgtgtt tgggatggca agccaaagaa atgtgggtaa cgacgcgccc
6121 ggctcaacca ggtcccatga ggcggtgatt tcaacctaca gccccagatt tgttcctaaa
6181 ttaggctctg tcaatttcaa aagcaatgac gatgatttcc aattgcagcc aacaagattc
6241 acaccagtgg gcattaatga tgatggcaac caaccattca gacaatggga actaccagat
6301 tattcagggg tgcttacctt gaatatgaac cttgcccccc ctgttgctcc aaatttccct
6361 ggcgaacaat tactattctt cagatcttct gtgccatgtt caggaggtta caaccaaggt
6421 attatagatt gccttatccc ccaagaatgg atccaacatt tctaccagga atcagcacct
6481 tctcagtcag aagtggccct aatcaggtac gtcaaccccg acacgggtcg tacactgttt
6541 gaggcaaaat tgcataggtc aggctatatc actgtggctc attctggaga ctatcctctt
6601 gttgttccgg ctaatggata ttttagattt gactcttggg taaatcagtt ttactcactc
6661 gccccaatgg gaactgggaa tgggcgaagg agggctcagt aatggctgga gctttcattg
6721 caggattggc gggtgacatg ctcacgtcat ccgtgggctc cctggtgaac gcaggggcaa
6781 acgccatcaa ccaaaagata gactttgaaa acaacaaaca actccagtct gcttcctttc
6841 aacatgataa agagatgctc caagcgcagg tgaacgcaac caagcagctg caatctgaga
6901 tgatagccct aaaacagggg gttttggccg caggcggctt ttcccccact gatgcagcga
6961 ggggggccat cggtgcaccc atgacaaagg tgcttgactg gtctggcact cgatactggg
7021 ctcccaattc cacaaagaca actggttatt cggggcaatt cacctcttca cctgtgcaca
7081 tgcccagccc gagtgtccca caatcaaaac ccgcaaagcc caagtctcta ggttcttctt
7141 cttcttctag tagtgtttac agtatgtcta cccaattaac ttctctaaca tctggctctt
7201 ctagtaatgc ttcttctgct tctacaaaat tgacaaattt gagctccggc tcttctcaaa
7261 acagaacagc agagtgggtg aaccaacaga gaagtctcag ccctttcatg agtggcgcac
7321 tcaatatctc gcatgtcacg ccaccttcaa gtagggcctc cagttctggg acggtctcaa
7381 ccgtgcccaa ggaagttttg gactcctgga catctgcatt caacacacgc agacagccgc
7441 tcttcgcaca cctcagagtg aggggggagt cacgtgttta gtgaaaagaa ataattggct
7501 ataatatgat ttctttaaaa tttaaatttg gctaatttgt atctttt
//