Typing tool
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Typing tool
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Complete norovirus genomes
| PV750876 | GII.17 | |
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| GII.P17 |
ORF1: 1..5102
ORF2: 5083..6699
ORF3: 6699..7478
LOCUS PV750876 7545 bp RNA linear VRL 26-NOV-2025
DEFINITION Norovirus GII isolate O2_Patient_3(2)_GER nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV750876
VERSION PV750876.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7545)
AUTHORS Tohma,K., Jacobsen,S., Altmann,B., Kendra,J.A., Landivar,M., De
La,O. Jr., Fernandez-Garcia,M.D., Gomes,K.A., Chudnovsky,S.,
Ford-Siltz,L.A., Pilewski,K.A., Gao,Y., Mazo,I., Niendorf,S. and
Parra,G.I.
TITLE GII.17 norovirus re-emerged in the 2020s as a result of dynamic and
adaptive evolutionary processes
JOURNAL Nat Commun (2025) In press
PUBMED 41285779
REMARK Publication Status: Available-Online prior to print
REFERENCE 2 (bases 1 to 7545)
AUTHORS Kutter,J.S. and Fernandez-Garcia,M.D.
TITLE Direct Submission
JOURNAL Submitted (06-JUN-2025) Enterovirus And Viral Gastroenteritis,
Instituto de Salud Carlos III, Ctra. Majadahonda-Pozuelo, Km 2,
Majadahonda, Madrid 28220, Spain
COMMENT ##Assembly-Data-START##
Assembly Method :: Metaspades v. v. v3.14.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7545
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="O2_Patient_3(2)_GER"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Spain: Getafe, Madrid"
/collection_date="25-May-2024"
/note="genotype: GII.17"
gene <1..5102
/gene="ORF1"
CDS <1..5102
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XUS55864.1"
/translation="ASNDASVAVAGKNNNNDNVKSSSDSLFSNMTVTFKKALGARSKQ
PPPGETKQALRPPRPPTPELVKKIPPPPPNGEDEPKVTYKVGEGVSGLPDLTTVAQPD
AQNTAYSVPPLSQREVGEAREPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAIS
LAKIELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLELNDS
WLSRRMVQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGK
LKPLNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAIIAPLLGDYEMQGPED
LAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFP
KKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDALATYMRTLDLEEEKARKLSS
KSASPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLAREL
AKKVASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEK
AKRDFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKSGNTPHGKGVVKSLTIGSLIARA
SGLLHERMDEFELQGPNLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTL
DELKQAIKNITIKKCQIVYNGCTYTMESDGRNKVVVEKVQNATVQTNNELAGALHHLR
SARIRYYVKCFQEAIYSILQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKGGC
PKPRDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSP
SLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEG
TVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYW
SGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
STMIRCARAFGGLMDELKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWTRGP
NHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQE
SMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..992
/gene="ORF1"
/product="p48"
mat_peptide 993..2090
/gene="ORF1"
/product="NTPase"
mat_peptide 2091..2627
/gene="ORF1"
/product="p22"
mat_peptide 2628..3026
/gene="ORF1"
/product="VPg"
mat_peptide 3027..3569
/gene="ORF1"
/product="Pro"
mat_peptide 3570..5099
/gene="ORF1"
/product="RdRp"
gene 5083..6699
/gene="ORF2"
CDS 5083..6699
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUS55865.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRSHEAVISTYSPRFVPKLGSVNFKSNDDDFQLQPTRFTPVGIND
DGNQPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLFFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSEVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6699..7478
/gene="ORF3"
CDS 6699..7478
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUS55866.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSVPQSKPAKPKSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 tggcgtctaa cgacgcttcc gttgccgttg ctggcaaaaa caacaacaac gacaatgtaa
61 aatcttcaag tgacagcttg ttttctaaca tgactgttac ttttaagaaa gccctcgggg
121 cgcggtctaa gcagccgccc ccgggagaaa caaaacaagc gctaagacca ccaaggccgc
181 cgacaccgga attggtgaag aaaatacccc cacctccccc caatggcgag gatgaaccaa
241 aggtgacgta taaggtggga gaaggtgtgt ctgggctgcc cgacttgaca accgtggcac
301 aacctgacgc acagaacaca gcctatagtg tccccccact tagccagaga gaggtcggcg
361 aagctagaga accgttgcct ggctccattc tggaaatgtg ggatggtgag atctaccact
421 atgggctgta tgttgagcgg gggcatgtgc tgggagtgca caaaccacct gctgcaataa
481 gccttgccaa aattgagtta acaccgctgt ctctctactg gagagtggtc tacactcccc
541 aatacttgat agctccagag accctcaaga atttaaatgg agaggctttc ccatacacgg
601 cctttgacaa caactgttat gccttctgtt gttgggttct agaactcaac gactcctggc
661 ttagcagaag aatggtccaa agaacaaccg gattcttcag accgtatcag gactggaaca
721 gaaaaccctt accaaccatg gatgaaccaa aaatcaagaa ggccgcgaat gctgttctgt
781 gtgctctctc ctcactcttc actaggccca tcaaagatgt cattggaaag cttaaaccac
841 taaacattat gaacatactg gcaacttgtg attggacttt tgcgggcata gtggaatcca
901 tgatccttct tgctgaactc tttggggtgt tctggacgcc cccagatgtg tctgcaataa
961 ttgctccctt actcggtgac tacgagatgc aaggccccga agacctggcc gtggaacttg
1021 tgcccgtggt aatgggagga ataggtttgg tgttaggatt caccaaggaa aagatcggca
1081 agatgctttc atcagctgca accacactca gggcctgtaa ggatctagga tcttatgggt
1141 tggagatact caaactggtc atgaagtggt tcttccccaa gaaggaggag gccaacgagt
1201 tagccatggt gagggccatt gaggatgcag ttctggattt ggaggcaata gaaaacaacc
1261 acatgaccac tctccttaag gacaaagacg ccctggccac atacatgagg actcttgact
1321 tggaagaaga aaaagcaagg aaactatctt ccaaatcggc gtcacctgac atcgtgggca
1381 cagtaaacgc attattggca agaatagcag ccgccaggtc actggtccac aaggctaagg
1441 aggagctctc gagcagacag agacctgttg ttgtaatgat atcaggtagg ccaggtatag
1501 gaaagaccca tctggccaga gagctagcca agaaggttgc gtcaacactg tcaggcgacc
1561 aaaggattgg actgataccc agaaatggcg tcgaccattg ggacgcctac aaaggagagc
1621 gggtggttct gtgggatgac tatggcatga gcaaccctat acaggacgca ctgaggctcc
1681 aagaattggc tgacacctgt cctctgaccc taaattgtga cagaattgaa aacaaaggaa
1741 aagtgttcga cagtgacgcc ataatcataa cgaccaacct tgcaaaccca gcaccattgg
1801 attatgtcaa ctttgaggct tgttccagac gcatagactt cttggtgtat gcagacgcac
1861 ctgacatcga gaaggctaag cgtgacttcc ctggccaacc agatatgtgg aaagaccatt
1921 acagatcaga cttctcacac attaaacttc agctcgcacc acagggaggc tttgataaga
1981 gtggcaacac cccacatggt aaaggtgtgg ttaagtctct gacgattggt tctctgatcg
2041 ccagggcttc tggcttgctc catgagagaa tggatgaatt cgagctccaa ggccccaact
2101 taccaacctt caatttcgac cgtaacaaag tcgccgcctt cagacaattg gcagctgaaa
2161 acaaatacgg tcttatggac acactgaggg tcggcaacca actgaaaagt gtcaaaaccc
2221 tggatgagct gaagcaggct ataaagaaca tcaccatcaa gaagtgccag atagtgtaca
2281 atggatgcac ctacaccatg gaatctgatg ggaggaacaa ggttgtggtt gaaaaggttc
2341 aaaatgcaac agtccaaacc aacaatgaac ttgcaggagc actccaccac ctgagatctg
2401 caagaataag gtactatgtc aaatgtttcc aagaagctat ttactctata ctccaaattg
2461 ctggtgcagc cttcgtcacc acacgcatcg tgaggcgcat gaacatctca aacctctggt
2521 cgaagccacc cgtcgaagag ggtgatgagc ctgaagacaa aggggggtgc cccaagccta
2581 gggatgaaga tgacctcact attgactcca aagacatcaa agcagaaggt aagaagggca
2641 agaacaaatc tggccggggc aagaaacaca cagctttctc atccaagggc ctcagtgatg
2701 aagagtacga tgagtacaag agaatcaggg aggagagaaa tggcaagtac tcaatagaag
2761 aatacctcca ggatagggat agatactatg aagagcttgc aattgctaag gccactgagg
2821 aagacttctg tgaagaggag gaaatcaaaa ttcgccagag aatcttccgg cccaccagga
2881 agcagcggaa agaggaaaga gccacgcttg ggctcgtcac aggatcggaa atcagaaaga
2941 ggaacccaga tgattttaag ccaaaaggaa aattgtgggc tgatgacaac aggagtgtgg
3001 actacaatga gaggatagat tttgaggctc ccccaagtgt ttggtctagg atagtcaact
3061 ttggtacagg atggggattc tgggtctccc caagtctctt tataacttca acacatgtca
3121 taccaaaagg aatcactgag gcctttggag ttcccattaa ccaaattcaa attcacaaat
3181 ctggagagtt ttgccgcttg cggtttccaa aaccaatcag gccagacgtg agtggaatga
3241 tcttagaaga gggtgcccct gaaggcactg ttgtctccat tctcatcaag aggacgacag
3301 gggaactgat gcctctcgca gtcagaatgg gaactcatgc cacaatgaaa atccaaggta
3361 gaacagtggg cggtcaaatg ggcatgcttc tcactggctc aaacgccaaa agcatggacc
3421 taggcacaac accaggtgac tgtgggtgcc catacatata caaaaggggc aatgacttcg
3481 tggtcattgg ggtgcacact gcagcagccc gcggaggtaa cacggtcata tgtgccacac
3541 aggggagtga aggcgaagcc accctcgaag gaggtgacaa caagggcacc tattgtggag
3601 cccccatctt gggtcctggc aacgcaccaa aattgagcac aaaaacaaaa ttctggagat
3661 cttctaacgc gccgctcccg ccaggcacct atgaaccagc ataccttggt ggaaaagacc
3721 cgcgtgtgaa gggaggccca tctctacaac aggttatgag agaccaactc aaacctttta
3781 cagagcccag agggaagcca ccaaaaccaa gtgtcttaga atcagcaaag aagaccatca
3841 ttaatgttct ggaacaaacc attgaccccc ctgaaaagtg gtcatatgcc caagcttgtg
3901 catccctcga caagacaacc tccagtggat acccgcatca cgtccggaag aatgactact
3961 ggagtggtga atccttcacg gggaaacttg cagaccaggc ctcaaaagca aatctcatgt
4021 atgaggaagg taagcacatg caaccagttt acaccgcagc actcaaagac gagctcgtga
4081 aaactgacaa aatttatggc aagatcaaga aaagactcct gtggggctct gacctatcca
4141 ccatgattcg atgcgccagg gcatttggtg gcctcatgga cgagctcaaa gcaaattgta
4201 tcacactccc tatcagagtt ggtatgaaca tgaatgaaga tggtcccata atatttgaaa
4261 agcactccag gtacaggtac cactatgatg ctgattattc ccgctgggat tccacacaac
4321 agcgggcagt gctggaagcg gcacttgaaa tcatggtgag attttctgct gagccacagt
4381 tggcacaaat agtggcagag gacctgctat caccaagtgt ggttgatgtg ggcgatttca
4441 aaattactat taatgaaggc ctaccatctg gcgtgccttg cacttcacaa tggaattcta
4501 ttgcccactg gttactcacc ctatgtgccc tgtctgaagt gacaggacta ggccctgaca
4561 tcatacaagc caactccatg tactctttct atggtgatga tgagattgtg agcacagaca
4621 taaaattaga cccagagaaa ttgactgcaa aactcaaaga atatggtctt aaacccaccc
4681 ggcctgacaa gactgagggg ccactggtaa ttagtgagga cctgaatggg ttgactttcc
4741 tccgccgaac agtcacccgc gatccagcgg gttggtttgg aaagttggac caaaactcca
4801 tcctcagaca gctgtactgg acaaggggac ccaaccatga agaccccagt gagactatga
4861 taccacacgc acagagacct gtgcagctca tggcattgct aggagaatcc tccctacatg
4921 gaccctcatt ttacagcaag gttagcaagc tggttatatc tgaacttaaa gagggaggaa
4981 tggattttta tgtgcccaga caagagtcaa tgttcaggtg gatgaggttc tcagatctaa
5041 gcacatggga gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgaat
5101 gacgccgctc catctaatga tggtgctgct ggtctcgtac cagagggcaa taacgagacc
5161 cttcccctag aaccagttgc gggcgcagct atagccgcac ccgtcactgg ccaaaataat
5221 ataattgacc cctggattag aacaaatttt gtgcaagcac caaatggaga gttcacagtg
5281 tcacccagaa actctcctgg agaaatttta ctaaacctag agttgggccc tgatctgaac
5341 ccttatttgg ctcatttgtc aaggatgtat aatggatatg ctggtggagt tgaagtccag
5401 gtcctcctgg cagggaacgc gttcactgcc gggaagatcc tcttcgccgc tgtcccgcca
5461 aattttccgg tggaattctt aagcccagcc cagattacaa tgctcccaca tataatagta
5521 gatgttagga ctcttgaacc aattatgatc ccattacctg atgttaggaa tacattcttc
5581 cactataata atcagcccaa cagccgcatg agattagtgg ctatgctcta cacccccctt
5641 agatctaatg gctcaggtga tgatgttttc actgtttctt gcagggtttt gactaggcct
5701 actcctgatt ttgagttcac ttatctagtg ccaccctctg ttgaatctaa gactaaaccc
5761 ttttctttac ccattctaac cctttctgag ctcacaaatt cgaggttccc ggtccccatc
5821 gattcgcttt tcaccgccca aaataatgtg ttgcaggtgc agtgtcaaaa tggcaggtgc
5881 acacttgacg gtgagctaca aggcacaacc cagttgctcc catctggcat ctgtgcgttc
5941 aggggacggg tgacagcaga aactgacaat cctgacaagt ggcacatgca actgcaaaac
6001 cttaatggca caacatatga cccaactgat gatgtgccag ccccactggg tacacctgac
6061 ttcaagggcg tcgtgtttgg gatggcaagc caaagaaatg tgggtaacga cgcgcccggc
6121 tcaaccaggt cccatgaggc ggtgatttca acctacagcc ccagatttgt tcctaaatta
6181 ggctctgtca atttcaaaag caatgacgat gatttccaat tgcagccaac aagattcaca
6241 ccagtgggca ttaatgatga tggcaaccaa ccattcagac aatgggaact accagattat
6301 tcaggggtgc ttaccttgaa tatgaacctt gccccccctg ttgctccaaa tttccctggc
6361 gaacaattac tattcttcag atcttctgtg ccatgttcag gaggttacaa ccaaggtatt
6421 atagattgcc ttatccccca agaatggatc caacacttct accaggaatc agcaccttct
6481 cagtcagaag tggccctaat caggtacgtc aaccccgaca cgggtcgtac actgtttgag
6541 gcaaaattgc ataggtcagg ctatatcact gtggctcatt ctggagacta tcctcttgtt
6601 gttccggcta atggatactt tagatttgac tcttgggtaa atcagtttta ctcactcgcc
6661 ccaatgggaa ctgggaatgg gcgaaggagg gctcagtaat ggctggagct ttcattgcag
6721 gattggcggg tgacatgctc acgtcatccg tgggctccct ggtgaacgca ggggcaaatg
6781 ccatcaacca aaagatagac tttgaaaaca acaaacaact ccagtctgct tcctttcaac
6841 atgataaaga gatgctccaa gcgcaggtga acgcaaccaa gcagctgcaa tctgagatga
6901 tagccctaaa acagggggtt ttggccgcag gcggcttttc ccccactgat gcagcgagag
6961 gggccatcgg tgcacccatg acaaaggtgc ttgactggtc tggcactcga tactgggctc
7021 ccaattccac aaagacaact ggctattcgg ggcaattcac ctcttcacct gtgcacatgc
7081 ccagcccgag tgtcccacaa tcaaaacccg caaagcccaa gtctctaggt tcttcttctt
7141 cttctagtag tgtttacagt atgtctaccc aatcaacttc tctaacatct ggctcttcta
7201 gtaatgcttc ttctgcttct acaaaactga caaatttgag ctccggctct tctcaaaaca
7261 gaacagcaga gtgggtgaac caacagagaa gtctcagccc tttcatgagt ggcgcactca
7321 atatctcgca tgtcacgcca ccttcaagta gggcctccag ttctgggacg gtctcaaccg
7381 tgcccaagga agttttggac tcctggacat ctgcattcaa cacacgcaga cagccgctct
7441 tcgcacacct cagagtgagg ggggagtcac gtgtttagtg aaaagaaata attggctata
7501 atatgatttc tttaaaattt aaaatttggc taatttgtat ctttt
//