Typing tool
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Typing tool
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Complete norovirus genomes
| PV746278 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 5..5104
ORF2: 5085..6707
ORF3: 6707..7513
LOCUS PV746278 7518 bp RNA linear VRL 10-JUN-2025
DEFINITION Norovirus GII isolate HuNoV/RU/SVE/GII.P16_GII.4/1987.1_24
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION PV746278
VERSION PV746278.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7518)
AUTHORS Bykov,R.O., Itani,T.M., Chalapa,V.I., Semenov,A.V.,
Pletenchuk,D.I., Yesaulkova,A.Y., Kozlovskikh,D.N. and Romanov,S.V.
TITLE Direct Submission
JOURNAL Submitted (05-JUN-2025) laboratory of enteral viral infections,
Federal Scientific Research Institute of Viral Infections (Virome)
Federal Service for Surveillance, letnyaya, Ekaterinburg
Ekaterinburg, Russia
COMMENT ##Assembly-Data-START##
Assembly Method :: DRAGEN v. 4.3 or MAY-2025
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7518
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="HuNoV/RU/SVE/GII.P16_GII.4/1987.1_24"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Russia"
/lat_lon="56.50 N 60.35 E"
/collection_date="05-Jun-2025"
/note="genotype: GII.P16_GII.4"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XUR19360.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEVFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRIAAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQSEPETKEE
ALKSEDDEFVISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVSIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
SGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGNPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGRIKKRLLWGSDL
STMVRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFAAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLDGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 5..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6707
/gene="ORF2"
CDS 5085..6707
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XUR19361.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNIIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6707..7513
/gene="ORF3"
CDS 6707..7513
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XUR19362.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNAGHFSTPQPSGALPGRANFRDAAPARGPSTRPS
NSSTATSVCSNQTISTRLGSTAGSGTSVSSLPSTTRTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgctac cgttgccgtt gcttgcaaca acaacaacga
61 caaggaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttccacct taaagaaagc
121 cctcggggct aggcccaaac agcctgcccc gagagacaaa ccacaaaagc ccccaagacc
181 accaactcct gagttggtca agaggatacc ccctcctcca cctaatggcg aagaagagga
241 agaaccagtc attaggtatg aggttaagag cggaatctct ggcctgcccg agctcacaac
301 agtcccccaa ccggacgtgg ccaacacagc attcagtgtt ccaccactga gcttgagaga
361 aaacagggag gccaaggaac cgctaacagg ggcaatatta gagatgtggg atggagagat
421 ataccactat ggcctatacg tggagaaagg cctggtgttg ggtgtgcaca aaccacctgc
481 agccataagc atggcaagag tggaactgac gccgctgtca ttatactggc gtgtagtgta
541 cactccccaa tacctcatct cccctgaaac tcttaggagg ctcaacggag aggttttccc
601 ttacaccgcc tttgacaata actgctatgc cttttgttgc tgggtgctag acctcaacga
661 ctcatggctt agcaggagaa tggtacagag aacaacgggc ttcttcagac cttaccaaga
721 gtggaacaga aaacccctgc ctaccatgga tgactccaaa attaagaagg tggcaaacat
781 attcctatgt tcattgtcta cattattcac caggcccata aaagatctca taggaaaaat
841 taaaccatta aacatattga acattctggc aacgtgtgac tggacgtttg ctgggatagt
901 ggagtctcta atattacttg ctgaactctt cggagttttc tggacacccc cagacgtgtc
961 tgctatgatc gctcccttgc tcggggacta cgagttgcag gggccagagg acctcgctgt
1021 tgaactcgtg cctgtggtaa tgggagggat tggtttggtg ttgggattca ccaaagagaa
1081 aattggcaaa atgttgtctt cggcagcatc aacactcagg gcttgcaaag atcttggtgc
1141 ctatggttta gagatactaa aattggtcat gaagtggttc ttcccaaaga aagaggaagc
1201 caatgagcta gccatggtga gggccataga ggatgctgta ctagaccttg aggcaataga
1261 aaataaccac atgacaaccc tgttgaaaga caaagacagc ttagcaacat acatgaagac
1321 actagacatg gaggaggaga aagccagaag gttatccaca aaatctgcat cccctgacat
1381 agttgggaca atcaacgccc tactggctcg aatagcagcg gccaggtcat tagtccacag
1441 ggccaaggaa gagctatcta gcaggataag accagtagtt gttatgatat ctggcaaacc
1501 aggaataggc aaaactcatc tggccaggga ggtggcaagg aaggtggctt ccactcttac
1561 aggggaccag agagtcggac tcattccgag gaacggtgtg gaccattggg atgcatacaa
1621 aggtgagaga gtcgtgctgt gggacgacta tggcatgagt aaccccattc atgatgctct
1681 tcgcatacaa gaattggctg atacgtgtcc ccttacctta aattgtgaca gaattgaaaa
1741 taagggaaaa gtttttgaca gtgaagtcat aataattaca acaaaccttg ccaatccagc
1801 cccacttgat tatgtcaact ttgaggcttg ttccaggaga attgacttcc tggtgtacgc
1861 tgaggcacca gaagtagaga aggcaaagcg ggacttccct ggtcagccag atatgtggaa
1921 ggacgccttc aagccggact tttcacacat caagctgcaa cttgcacctc agggcggctt
1981 tgacaagaat ggcaacaccc cacatgggaa aggagtgatg aagaccctca ctaccggctc
2041 tctgatcgct cgtgcatcag gcctgctgca tgagaggatg gatgaatttg aactccaagg
2101 ccccacaatc accaccttca atttcgaccg gaacagaatc gcagcgttca gacaattggc
2161 tgcagaaaac aagtatggat tagtggacac catgaaagtt ggcaatcaat taaaaggagt
2221 gaaaaccatg gaagaactca aacaagcaat caggaatgtg accatcaaga ggtgccggat
2281 catttacggt ggctctacat atgaccttga atctgacggc aagggcaaag ttttagtgga
2341 aaaggtcaag aacacctctg tacagaccaa caacgagttg gccggggcct tgcaccatct
2401 caaacacgcc cgaatcagat actatgtcaa atgcgtgcaa gaagcagtct attccatcat
2461 acaaattgcc ggcgctgcgt ttgtcaccac gcgcattgca cgccgcatga acatacaaga
2521 actctggtcg aagccacaat tagatcaaag tgaaccagag actaaggaag aggccctcaa
2581 gtcagaagac gacgagttcg tcatatcttc taaggacatc aaggaggaag gaaagaaggg
2641 caaaaataaa actggccgtg gcaagaaaca cactgcattc tccagcaagg gcttgagcga
2701 tgaggagtat gacgagtata aaaggataag agaagagaga aatgggaagt actctataga
2761 ggagtatctt caagacagag acaggtacta tgaggagctc gccattgcca aggccacgga
2821 agaagacttc tgtgaagagg aggagattaa aatccgtcag agaattttcc gtcccaccag
2881 gaaacaaaga aaggaagaga gggccacatt agggctagta acgggttcag aaatcagaaa
2941 gagaaaccct gatgacttca aacccaaagg gaagctgtgg gccgatgaca acagaagtgt
3001 tgattacaat gaaaaactgg actttgaggc ccccccaagc atatggtcta ggatcgtgag
3061 ctttggttct ggctggggct tctgggtatc accaagtctg tttataacat caactcatgt
3121 gatccccgca ggcataacag aagcatttgg agtctccatc aaacaaattc agatccacaa
3181 atcaggtgaa ttttgccggt tcaggttccc aaaaccaatt agaccagatg ttacaggaat
3241 gatcttggaa gaaggtgcgc ctgagggtac cgtggcaact gtgctcatca aacgccccac
3301 cggagagctc atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaagg
3361 ccgcatggtt ggcgggcaga tgggtatgtt gctcactgga tcaaatgcta aaggaatgga
3421 cttgggaaca actcctggtg actgtggctg tccttacatc tataaaaggg gcaatgacta
3481 tatagtcatt ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca tttgtgccac
3541 acagggaagt gagggtgagg caactcttga gggtggagat gacaaaggaa catactgtgg
3601 ggcacccatt ctaggccctg ggggtgcacc aaaattgagc accaaaacca aattttggag
3661 gtcatcgaac acgccccttc caccagggac atatgagcct gcctacctcg gtggccgtga
3721 cccgcgtgtt aagggtgggc cctccttgca gcaggtaatg agagaccagt tgaagccatt
3781 cactgaaccc agtggcaaac ctccaagacc aagtgtacta gaagcagcca aacaaaccat
3841 catcaatgtc ctcgaacaaa ccctggatcc tccacaaaaa tggacgtacg cacaggcgtg
3901 tgcctcactt gacaaaacca cctccagcgg gaacccccat cacgtccgaa agaatgaatt
3961 ctggaatggt gagaccttca ctggaaaatt ggcagaccaa gcatcaaaag caaatctaat
4021 gtttgaggaa gggaaacata tgacaccagt gtatacagca gcactcaagg acgagctagt
4081 taagactgag aagatctatg gaaggatcaa gaagaggctg ctctggggct ctgacttgtc
4141 caccatggtc cggtgtgcta ggtcatttgg tgggctcatg gacgagatga aggcacactg
4201 catatcactc ccagtccgag taggcatgaa tatgaatgaa gatggcccaa taatatttga
4261 aaaacattcc agatataagt accactatga tgcagactac tctcgttggg attcaacaca
4321 acagagggca gtactggcag cagccttaga aatcatggtc agattcgctg cagaaccaca
4381 actggcacaa atagtcgctg aggatctgct ggcccctagt gtagtggatg taggagactt
4441 caaaattaca ataaatgaag ggctcccctc tggtgttcca tgtacttctc aatggaactc
4501 cattgcacac tggctgctaa ctctctgtgc cttgtctgaa gtcaccaaac tgtcccctga
4561 cattatacaa gcaaattcca tgttctcatt ttacggtgat gacgagattg ttagcaccga
4621 cataaaatta gaccctgaac aattaaccgc caaattgaag gagtacggcc tgaaaccaac
4681 ccgcccagac aaaaccgagg gacccctgat catcagtgag gatttggacg gactcacttt
4741 cctccgaagg acggtgactc gtgacccagc tggctggttt ggtaaactgg accagagctc
4801 cattttgagg cagatgtact ggactagagg gccaaaccat gaagacccca atgagacaat
4861 gataccccat tctcagagac ccatacagct catggcactg cttggtgaag cctctcttca
4921 cggaccctct ttctatagta aaatcagcaa attggtcata actgaactca aggagggtgg
4981 gatggacttt tacgtgccaa gacaggaacc catgttcagg tggatgaggt tttctgactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccaacttt gtgaatgaag atggcgtcga
5101 gtgacgccaa cccatctgat gggtccgcag ccaacctcgt accagaggtc aacaatgagg
5161 ttatggcttt ggagcccgtt gttggtgctg ctattgcggc acctgtagcg ggccaacaaa
5221 atataattga cccctggatt agaaataatt ttgtacaagc ccctggtggg gagtttacag
5281 tatcccctag aaacgctcca ggtgaaatac tatggagcgc gcccctaggc cctgacctaa
5341 atccctacct atcccatttg gccagaatgt acaatggtta tgcaggtggt tttgaagtgc
5401 aagtaattct cgcggggaac gcgttcaccg ccgggaagat catatttgca gcagtcccac
5461 caaattttcc aactgaaggc ttaagtccta gccaggtcac tatgttcccc catataatag
5521 tagatgttag acaattggaa cctgtgctga ttcccttacc cgatgttagg aataatttct
5581 atcattacaa tcagtcaaat gactccacta ttaagttgat agcaatgtta tatacaccac
5641 ttagggctaa caatgctgga gatgatgttt tcacagtctc gtgccgagtt cttacgagac
5701 catcccccga ttttgatttc atattcttag taccacccac agttgagtca agaactaaac
5761 cattctccgt cccagtttta actgttgagg agatgactaa ttcaagattc cccatccctt
5821 tggaaaagtt gttcacaggc cccagcagtg cctttgttgt tcaaccacaa aacggcaggt
5881 gcacaactga tggcgtgctc ctaggcacca cccaactgtc tcctgtcaac atctgcacct
5941 tcagagggga tgtcacccac atcacaggta gtcgcaacta cacaatgaat ttggcttctc
6001 aaaattggaa caactatgac ccaacagaag aaatcccagc ccctctagga actccagatt
6061 ttgtgggaaa gattcaaggc atgctcaccc aaaccacaag gacagatggt tcaacacgcg
6121 gccacaaagc tacagtgtac actgggagcg ccgactttgc tccaaaactg ggtagagttc
6181 aatttgaaac tgacacagac catgattttg aagctaatca aaacacaaag ttcaccccag
6241 tcggtgtcat ccaagatggt agcaccaccc accgaaacga accccaacag tgggtgctcc
6301 caagttactc aggcagaaat actcacaatg tacatctggc ccccgctgta gcccccacct
6361 ttccgggtga gcaacttctc ttctttagat ctaccatgcc cggatgtagc gggtacccca
6421 acatggattt ggactgtctg ctcccccagg aatgggtgca gtatttctac caagaggcag
6481 ccccagcaca atctgatgtg gctctgctaa ggtttgtgaa tccagacaca ggtagggttt
6541 tgtttgagtg caagcttcac aaatcaggct atgttacagt ggctcacact ggccaacatg
6601 acttggttat cccccccaat ggttacttta ggtttgattc ctgggtcaac cagttctaca
6661 cgcttgcccc catgggaaat ggaacggggc gtagacgtgc agtataatgg ctggagcttt
6721 ctttgctgga ttggcatctg atgtccttgg ctctggactt ggttccctta tcaatgctgg
6781 ggctggggcc atcaaccaaa aagttgagtt tgagaataac agaaaattgc aacaagcatc
6841 cttccaattt agcagtaatt tgcaacaggc ttcctttcaa catgataaag agatgctcca
6901 agcacaaatt gaggccacca aaaagctcca acaggaaatg atgagagtta aacaggcaat
6961 gctcctagag ggtgggttct ctgagacaga tgcggcccgc ggggcaatta acgcccccat
7021 gacaaaggct ttggactgga gcgggacaag gtactgggcc ccagatgcta gaattacaac
7081 atacaatgca ggccactttt ccacccctca accatcgggg gcactgccag gaagagctaa
7141 ttttagggat gctgcccctg ctcggggacc ctccaccaga ccttctaact cttctactgc
7201 cacctctgtg tgttcaaatc aaactatttc aacaaggctt ggttctacag ctggttctgg
7261 aaccagtgtc tcgagcctcc cgtcaactac aaggactagg agctgggttg aggatcaaaa
7321 caggaatttg tctcctttca tgagaggggc ccacaacata tcatttgtca ccccaccatc
7381 tagcagatcc tctagccaag gcacagtctc aaccgtgcct aaagaaattc tggactcctg
7441 gactggcgct ttcaacacgc gcaggcagcc tctcttcgct cacattcgta agcgagggga
7501 gtcacgggtg taatgtga
//