Typing tool
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Typing tool
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Complete norovirus genomes
| PV640830 | GI.4 | |
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| GI.P4 |
ORF1: 1..5322
ORF2: 5306..6940
ORF3: 6940..7566
LOCUS PV640830 7600 bp RNA linear VRL 19-MAY-2025
DEFINITION Norovirus GI isolate 2023LW01 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION PV640830
VERSION PV640830.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7600)
AUTHORS Xiao,Y., Li,L.-L., Tan,Z.-X., Liu,Y., Li,J.-S. and Duan,Z.-J.
TITLE Molecular Characterization and Genetic Variability Analysis of
Norovirus Strains in the Gastroenteritis Outbreaks in Liwan
District, Guangzhou, 2023
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7600)
AUTHORS Xiao,Y., Li,L.-L., Tan,Z.-X., Liu,Y., Li,J.-S. and Duan,Z.-J.
TITLE Direct Submission
JOURNAL Submitted (14-MAY-2025) Laboratory, Guangzhou Liwan Center for
Disease Control and Prevention, Zhoumenxi Road No. 32, Guangzhou
510176, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7600
/organism="Norovirus GI"
/mol_type="genomic RNA"
/isolate="2023LW01"
/isolation_source="Anal swab"
/host="Homo sapiens"
/db_xref="taxon:122928"
/geo_loc_name="China: Guangzhou"
/collection_date="Mar-2023"
/note="genotype: GI.4[P4]"
gene <1..5322
/gene="ORF1"
CDS <1..5322
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="XTP39416.1"
/translation="AASAENTSDNSESIKNRFFTRLKNLGSNNKSIKIENTHMALNLI
SRGPSPAPQERPPKDQRDKPPRNVTETQQAMGWIDPPVDQNLPTWEELSQTEKQEILK
NNSNWFDAGGLAPASIPSGYVKNTEQQPPDHQVKWSINNGVDLGVDSLTTVPGPTWNL
CPMPPIDQRNNGPAQEPLIGDMIEFYEGHIYHYAIYIGQGKTVGVHSPQAAFSIARIT
IHPIAAWWRVCYVPTPDQRLSYDQLKELENEPWPYAAVTNNCYEFCCRILNLQDTWLE
RRLVTSSRFNHPAQDWSRDTPDFQQDSKLEIVRDAVLAAINGLVSKPFKDLLNKLKPL
NVLNLLSNCDWTFMGVVETIILLMELFGIFWNPPDVSSFIASLLPDMHLQGPEDLAKD
LIPLVLGGVGLAIGFTKDKVTKVMKSAVEGLRAATQLGQYGLEIFAVLKKYFFGGDQT
EKTLKDIETAVIDMEVISTTAVTQLVRDKQAARTYMNILDAEEEKARKLSVRHADPHV
VSTTNALISRISLARSALAKAQAEMTNRVKPVVIMMCGPPGIGKTKAAEYLAKRLANE
IRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMSKIADDCNKLQAIADTAPLTLNCD
RIEKKGLQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYCTAPDVEQTRRTNPG
DTGALKDCFKSDFSHLKMELAPQGGFDNQGNTPFGKGTMRPTTLNRLLIQAVALTMER
QDEFQMQGQVYDFDADRVSAFTSLARANGLGLISMASLGKKLRGVDSVHGLKNALSGY
TITPCSIKWQARVYDIESDGTNVHIKENTSAQTQRQQSIDTAALALTRLKAARAAAYA
ACIQSAITTILQMAGSAIVINRAVKRMFGAHPSTIALEGPPREHRCRAHLAKAAGGGP
IGHDDVIDKYGLCETEEEGTSEEMNVELPTATSEGKNKGKTKKGRGRRANYNAFSRRG
LSDEEYEEYKKIREEKNGNYSIQEYLEDRQRYEEELAEVQAGGDGGIGETEMEIRHKI
FYKSKKGRQNERRQLGLVTGSDIRKRKPIDWTPPKNDWADDNREVDYNEKLSFEAPPT
LWSRVVRFGSGWGFWVSPTVFITTTHVIPSGVREFFGEPIESIAIHRAGEFTQFRFSR
KVRPDLTGMVLEEGCPEGVVCSILIKRDSGELLPLAVRMGAIASMKIQGRLVHGQSGM
LLTGANAKGMDLGTLPGDCGAPYVYKRNNDWVVCGVHAAATKSGNTVVCAVQAGEGET
TLEGGDKGHYAGHEIIKHSKGPALSTKTKFWRSTPEPLPPGVYEPAYLGGRDPRVKGG
PSLQQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSMLEQTMDTPTPWSFSDACQSLD
KTTSSGHPYHKRKNDDWNGTSFIGELGEQAAHANNMYELGKSMKPLYTAALKDELVKP
EKVYQKIKKRLLWGADLSTVIRAARAFGPFCDAIKPHVIKLPIKVGMNSIEDGPMIYA
EHAKYKNHFDADYSAWDSTQNRQIMTESFAIMCRLTASPELASVVAKDLLAPSEMDVG
DYIIRVKEGLPSGFPCTSQVNSINHWLITLCAMSEVTGLSPDVIQSQSYFSFYGDDEI
VSTDIDFDPARLTQVLKEYGLRPTRPDKSEGPIILRRQVDGLVFLRRTISKDAAGFQG
RLDRGSIERQLWWTRGPNHDDPSETLIPHPQRKVQLISLLGEASLHGEKFYRKISSKV
IQEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRNLLPEFVNDDGV"
mat_peptide <1..1152
/gene="ORF1"
/product="p48"
mat_peptide 1153..2241
/gene="ORF1"
/product="NTPase"
mat_peptide 2242..2844
/gene="ORF1"
/product="p22"
mat_peptide 2845..3252
/gene="ORF1"
/product="VPg"
mat_peptide 3253..3795
/gene="ORF1"
/product="Pro"
mat_peptide 3796..5319
/gene="ORF1"
/product="RdRp"
gene 5306..6940
/gene="ORF2"
CDS 5306..6940
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XTP39417.1"
/translation="MMMASKDATPSADGATGAGQLVPEVNTADPIPIDPVAGSSTALA
TAGQVNLIDPWIINNFVQAPQGEFTISPNNTPGDVLFDLQLGPHLNPFLSHLSQMYNG
WVGNMRVRVVLAGNAFTAGKVIICCVPPGFQSRTLSIAQATLFPHVIADVRTLDPVEV
PLEDVRNVLYHNNDTQPTMRLLCMLYTPLRTGGASGGTDSFVVAGRVLTCPGPDFNFL
FLVPPTVEQKTRPFTVPNIPLKYLSNSRIPNPIEGMSLSPDQTQNVQFQNGRCTIDGQ
PLGTTPVSVSQLCKFRGRITSGQKVLNLTELDGSPFMAFAAPAPAGFPDLGSCDWHIE
MSKIPNSSTQSNPIVVNSVKPNSQQFVPHLSSITLDDNVSSGGDYIGTIQWTSPPSDS
GGANTNFWKIPDYGSSLAEASQLAPAVYPPGFNEVIVYFMASIPGPNQSGSPNLVPCL
LPQEYITHFISEQAPIQGEAALLHYVDPDTNRNLGEFKLYPGGYLTCVPNSSSTGPQQ
LPLDGVFVFASWVSRFYQLKPVGTAGPARGRLGVRR"
gene 6940..7566
/gene="ORF3"
CDS 6940..7566
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XTP39418.1"
/translation="MAQAIIGAIAASAAGSALGAGIQAGAEAALQAQRYQQDLTLQQN
SFNHDKEMLGYQVEMSNKLLAKNLNTRYSLLQAGGLSPSDAARAVAGAPVTRLVDWGG
VRVAAPQSFATTLRSGNFMAVPLPAQPKQKPLASEGYSNPAYDPMQRTASWVQSQNSS
RTWSPYHRQALQTVWVTPPGSTSSSSVSTAPRGYFNTDRLPLFANLRR"
ORIGIN
1 gctgctagtg ctgaaaacac tagtgacaat agtgaatcta taaagaaccg tttcttcaca
61 aggttgaaga atttaggttc taacaataaa tctataaaaa ttgaaaacac ccatatggcc
121 ctcaacttga ttagtagagg gccatctcca gccccacaag aaaggccccc caaagatcag
181 agggataaac ccccaaggaa tgtgactgaa actcaacagg caatggggtg gattgacccc
241 cccgtggatc agaacctacc aacctgggag gaattgagcc aaacagaaaa acaagagata
301 ctcaagaaca attcaaactg gtttgatgct ggtggactgg caccagctag tatcccttct
361 ggttatgtga aaaatacaga gcaacaaccc cctgaccacc aggtcaaatg gagtataaac
421 aacggggtcg atctgggagt ggacagtcta actactgtgc caggtccaac atggaacctg
481 tgccccatgc caccaattga ccaacgaaac aatggccctg cacaagagcc actcattggt
541 gatatgatag aattctatga aggacacatt taccattatg caatatatat tggccaagga
601 aaaactgttg gggtccactc accccaagcg gctttttcaa tagccagaat aaccatacac
661 cccattgctg cttggtggag ggtttgttat gtgccaacac ctgatcagag attaagttat
721 gaccaactca aagagcttga gaatgagcca tggccatatg ctgcagtcac caataattgc
781 tatgagttct gctgcagaat cctcaatctg caggatactt ggttggagcg ccgtctagtt
841 acgtccagtc gttttaacca tccagcacaa gactggtcta gggacacgcc tgacttccaa
901 caagatagca aactagaaat agtcagggat gctgtgcttg ctgcaattaa tggcttggta
961 tcaaaaccct tcaaagacct cctaaataaa cttaagccac tcaacgtgct taacctactc
1021 tccaactgcg attggacatt tatgggagta gtggagacaa taatattact tatggaactg
1081 tttgggatct tctggaaccc ccctgatgtg tccagcttca tagcttcact actacccgac
1141 atgcatctgc aaggaccaga agatctggct aaagatttga taccactggt gttggggggt
1201 gtagggcttg caattggatt taccaaggac aaggttacaa aggtcatgaa gagcgctgtt
1261 gaaggactta gggcagccac acaattgggc cagtatggtc tagagatatt tgcggtctta
1321 aagaaatact tctttggcgg agaccaaaca gagaagactt taaaggacat tgagacagcc
1381 gtaattgaca tggaggtcat ttcaacaact gctgtcactc aattagtcag ggacaagcag
1441 gctgcccgaa cctacatgaa catcttggat gccgaggaag aaaaggcaag aaagctttca
1501 gtcaggcatg cagaccccca tgtcgtgtcc acgactaatg ccctgatctc acgcatttct
1561 ttggctcgct ctgcacttgc taaggcacaa gctgagatga ctaacagagt taaaccagtg
1621 gtaataatga tgtgtggccc cccaggcata ggcaagacaa aggcagctga gtatcttgct
1681 aagagattgg ctaatgagat acggcctgga ggaaaagtgg gtctcgttcc aagggaggct
1741 gtggatcact gggatggata tcatggtgaa gaggttatgc tatgggatga ttatggtatg
1801 tcaaaaatag ccgatgactg taataaattg caggccatag ccgacacagc tccactcacc
1861 ttgaattgtg accggattga gaagaaaggg ttacagttcg tctctgatgc catagtgata
1921 acaacaaatg ccccaggtcc agcccctgtt gactttgtca atcttggccc agtgtgtcga
1981 cgtgtagact tcctggttta ttgcaccgca cctgacgttg aacaaacacg tcgcaccaac
2041 cctggagaca ctggagccct caaggattgt ttcaaaagtg acttctccca tctaaaaatg
2101 gagttggccc cacagggcgg atttgacaat caagggaaca ccccatttgg caaagggacc
2161 atgcggccta ccacgttaaa ccgtcttctc atacaagctg tggcgctaac catggagcgt
2221 caggatgaat tccagatgca gggccaagtg tatgattttg acgctgacag ggtatccgct
2281 ttcaccagtc tagcgagagc taatggtcta ggtctcatta gcatggcctc tctgggaaag
2341 aaattgaggg gtgtggactc agtccatggc ctcaagaatg cattatcagg ctacaccata
2401 accccttgta gtataaaatg gcaagccaga gtgtatgata ttgaatcgga tggcactaat
2461 gtacacataa aggaaaacac ctcagcccag acacaacgcc agcaatcaat tgacacagca
2521 gctctagcac tcactagact taaagcagca cgggcagcag cgtatgcagc ttgcatacaa
2581 agtgcaataa caactatctt gcagatggct gggtcagcca tcgttataaa tcgtgctgtc
2641 aaaaggatgt ttggggcaca cccaagcacc atagcccttg aaggaccacc aagagaacac
2701 cggtgtagag ctcacctggc caaagctgca ggtggtggac caataggtca tgatgatgtc
2761 attgataagt atggtctatg tgagactgaa gaagagggca ccagtgagga gatgaatgtg
2821 gagcttccca ccgccacttc tgagggtaaa aataaaggta aaaccaagaa aggaagaggc
2881 agaagagcca attacaatgc tttttcaagg cgaggtctga gtgatgaaga atacgaggag
2941 tataagaaga tcagggaaga aaagaatggt aactacagta ttcaggaata ccttgaagac
3001 agacaacgct atgaggaaga actcgcagaa gtgcaagctg gtggtgatgg aggcattggt
3061 gagacagaga tggagatccg acacaagatc ttctataaat ccaaaaaggg ccgtcaaaat
3121 gaacgccgcc agctaggatt agtcactggt agtgacatta gaaagagaaa accaattgat
3181 tggacccccc ccaagaatga ttgggcagat gacaacaggg aagtggatta caatgaaaaa
3241 ctcagttttg aagccccacc aaccctctgg agccgggttg tgagatttgg ctctgggtgg
3301 ggcttttggg tgagcccgac tgtttttatc accaccaccc acgttatacc atctggagtg
3361 cgtgaattct ttggagaacc catcgaatcc attgcaatcc accgtgctgg tgagtttaca
3421 caattcaggt tttcacgcaa agtccgccca gatttgactg ggatggtgtt ggaggaaggc
3481 tgccctgagg gtgtcgtgtg ttccatcctc attaaacgtg actctggtga actgctaccc
3541 cttgctgtcc gaatgggcgc tatagcgtcc atgaagatcc aagggaggtt agtgcatggt
3601 caatctggga tgctgcttac tggggccaac gccaagggga tggacttggg caccctacca
3661 ggtgattgtg gtgcccctta tgtgtacaag aggaacaatg attgggtggt ttgtggtgtg
3721 catgcagctg ccacgaaatc aggcaacact gtagtgtgtg ctgtccaggc tggggagggt
3781 gaaaccacct tagagggggg tgataaaggt cactatgctg gtcatgagat aattaagcac
3841 agtaagggcc cagctttatc aactaaaacc aagttctgga ggtcaacccc tgaaccacta
3901 ccgccaggtg tttatgaacc agcgtacctt gggggccgtg acccaagggt aaaaggtgga
3961 ccttccctac aacaagtcct gcgtgaccaa ctgaaaccgt ttgctgagcc acgaggtcga
4021 atgccagaac ctggtctact tgaggcagcc gtcgaaactg tcacatccat gcttgaacaa
4081 acaatggaca caccaacccc ttggtctttc tctgatgcat gccagtcact cgacaaaacc
4141 acaagttcgg ggcacccata ccacaaaagg aaaaatgatg attggaatgg aacttcattt
4201 attggggagc ttggagaaca ggcggcacat gccaacaata tgtatgagtt aggcaagtcc
4261 atgaaaccac tttacactgc agccctaaaa gatgagttag tcaagcctga gaaagtttat
4321 caaaagatca agaaaaggct cctctggggt gctgatctct caacagttat aagagctgcc
4381 agagcttttg gaccattttg tgatgccata aagcctcatg tcattaaact ccccatcaaa
4441 gttggtatga actccataga agatggccca atgatttatg cagaacatgc aaagtataag
4501 aatcattttg atgcagacta ttcggcctgg gattctacac aaaatagaca gatcatgact
4561 gagtcttttg caattatgtg tcgccttacg gcgtcacctg agttggcctc tgttgtagcc
4621 aaagatttac ttgcaccctc agaaatggat gttggtgatt acatcatccg tgtgaaggaa
4681 ggcttgccat cagggttccc ttgcacgtca caggtgaata gtataaacca ctggttaatc
4741 acattgtgtg ctatgtctga agtcacaggc ttatcacccg atgtcataca atcccagtct
4801 tacttttcct tctacggtga tgatgaaata gtctcaacag atattgattt tgaccccgcc
4861 cgcctcactc aagtgcttaa agaatatgga ttgagaccca cccgaccaga taagtcagaa
4921 ggacccatca tacttagaag gcaggtggat ggccttgttt tcttaaggag gacaatctca
4981 aaagatgctg cgggtttcca ggggaggctg gataggggct caattgaaag gcagctctgg
5041 tggactcgag gccctaacca tgatgacccc agtgagactc taatcccaca cccccagagg
5101 aaagttcaac ttatatccct tcttggtgag gcttccctcc atggtgagaa gttttacagg
5161 aaaatctcca gtaaagtcat acaggagata aagactggtg gtttggaaat gtatgtgcca
5221 ggctggcagg ccatgttccg ctggatgcgc ttccatgacc tcggattgtg gacaggagat
5281 cgcaatctcc tgcccgaatt cgtaaatgat gatggcgtct aaggacgcta caccaagcgc
5341 agatggcgcc actggcgccg gccagctggt accggaggtt aatacagctg accctatacc
5401 cattgaccct gtggctggct cctctacagc acttgccact gcaggccaag ttaatttgat
5461 tgatccctgg ataatcaata attttgtgca agccccccag ggcgaattca caatatcccc
5521 aaacaatacc cccggtgatg tgctttttga tttgcagtta ggacctcatt taaacccttt
5581 cctctcccat ctctctcaaa tgtacaatgg ctgggtgggc aacatgcgag tgcgtgttgt
5641 cttggctggt aacgctttca cggctgggaa ggttataatt tgttgtgtcc cccctggctt
5701 tcaatctcgt actctttcca tagctcaggc tactttattc ccccacgtta ttgctgatgt
5761 taggaccctt gaccctgtag aagtgcctct tgaagatgtc aggaacgtgt tgtatcataa
5821 taatgacacc caacccacca tgcgcctcct ttgcatgctg tacacccctc tccgtaccgg
5881 gggagcgtct ggtgggactg attctttcgt ggtagctggg cgtgtactta cttgcccagg
5941 ccctgacttt aacttcttat tcttggtccc tcccacagtc gagcaaaaga ctcgcccttt
6001 cactgtgcct aatatccctt tgaagtatct gtccaactcc agaatcccaa atcccattga
6061 aggtatgtca ttgtcacctg accagactca aaatgtccaa ttccaaaatg gcaggtgcac
6121 aattgacggt caacccctcg ggactacacc tgtctcggtt agccagttat gtaaatttag
6181 gggtaggatt acatctggac agaaggtgct caatttgaca gagttggatg gttcaccttt
6241 tatggccttt gctgcccctg cccctgcggg cttcccagat cttgggtcct gtgattggca
6301 tattgagatg agtaaaatcc caaattccag cacccagagt aacccaatag tagtcaattc
6361 tgttaagccc aatagtcaac agtttgttcc ccacttgtca agcatcaccc ttgatgacaa
6421 tgtttctagt gggggtgatt atattggtac tatacaatgg acctctcctc cttctgattc
6481 tggcggagcc aatacaaact tttggaaaat ccctgactat gggtctagct tggctgaagc
6541 ttcacagttg gcccccgctg tctatccacc tggtttcaat gaagtgattg tgtatttcat
6601 ggcatctata cctggcccca atcaatctgg gtcccctaac ttggtgccat gcctactccc
6661 ccaggaatat ataacacatt tcattagtga gcaggccccc attcagggtg aggccgcctt
6721 actccattat gtggacccag acaccaatcg taatttgggt gagtttaaat tgtatcctgg
6781 tggttattta acctgtgttc ctaatagttc tagtactgga cctcaacagc ttcctcttga
6841 tggtgttttt gtctttgctt cttgggtctc tagattttat caattaaagc ctgtgggaac
6901 agccggaccg gctagaggta ggcttggtgt ccgtagataa tggcccaagc cattatagga
6961 gccattgccg cctctgcagc cggcagcgcc ctgggtgctg gcatccaggc cggtgctgaa
7021 gctgcattac aggctcagag atatcaacaa gatttgactt tgcagcaaaa ttcttttaat
7081 catgataaag aaatgttagg ttatcaagtg gaaatgtcca ataagttgtt agctaagaat
7141 cttaataccc gctattctct tctccaggcg ggtggcctct ccccctctga tgcggctagg
7201 gctgtggccg gggcccctgt cactaggctg gtcgactggg gtggagtgcg tgttgcagca
7261 ccacaatcat tcgccaccac attgagatct ggcaatttca tggcagtgcc gctcccagct
7321 cagccaaagc agaagcccct tgccagtgag ggttattcca atcccgccta tgaccctatg
7381 cagcgtacag cttcttgggt tcaatctcaa aattccagtc ggacttggtc tccttaccat
7441 aggcaggccc ttcagactgt gtgggtgacc ccccctggct ctacctcttc ttcttctgtt
7501 tctaccgccc ctcgggggta ctttaataca gataggttgc ctctgttcgc aaacttgagg
7561 cgttaatgtt gtaataagat tagtgagcat cctattcaaa
//