Typing tool
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Typing tool
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Complete norovirus genomes
| PV282527 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5092
ORF2: 5073..6695
ORF3: 6695..7501
LOCUS PV282527 7541 bp RNA linear VRL 28-JUL-2025
DEFINITION Norovirus GII isolate p1630-BCM16-3 nonstructural polyprotein
(ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes,
complete cds.
ACCESSION PV282527
VERSION PV282527.1
DBLINK BioProject: PRJNA1195114
BioSample: SAMN45209638
Sequence Read Archive: SRR31712878
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7541)
AUTHORS Bhamidipati,S.V., Surathu,A., Ramani,S., Atmar,R.L., Estes,M.K.,
Muzny,D.M., Cregeen,S.J. and Doddapaneni,H.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2025) Molecular Virology and Microbiology, Baylor
College of Medicine, Alkek Center for Metagenomics and Microbiome
Research, 1 Baylor Plaza, Houston, TX 77030, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: VirMap v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7541
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="p1630-BCM16-3"
/isolation_source="Enteroids"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA: Houston"
/collection_date="01-Nov-2022"
/note="genotype: GII.4"
gene <1..5092
/gene="ORF1"
CDS <1..5092
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XPY62848.1"
/translation="ASNDASAAAVANSNNDIAKSSSDGVFSNMAVTFKRALGARPKQP
PPKEMPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEETN
TAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLAK
VELTPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKP
LNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTVNSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAKK
IAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKR
DFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMSDL
KQALKNIAIKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCAR
IRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMTNKDGCLKP
KDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGS
EIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVA
TLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGPGS
APKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQ
QRDVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHE
DPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..982
/gene="ORF1"
/product="p48"
mat_peptide 983..2080
/gene="ORF1"
/product="NTPase"
mat_peptide 2081..2617
/gene="ORF1"
/product="p22"
mat_peptide 2618..3016
/gene="ORF1"
/product="VPg"
mat_peptide 3017..3559
/gene="ORF1"
/product="Pro"
mat_peptide 3560..5089
/gene="ORF1"
/product="RdRp"
gene 5073..6695
/gene="ORF2"
CDS 5073..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPY62849.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHTTGSRNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6695..7501
/gene="ORF3"
CDS 6695..7501
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPY62850.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRDLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ggcgtctaac gacgcttccg ctgccgctgt tgccaacagc aacaacgaca tcgcaaaatc
61 ttcaagtgac ggtgtgtttt ctaacatggc tgtcactttt aagcgggccc tcggggcgcg
121 gcctaaacag ccgcccccga aggagatgcc acccagaccc ccgcgaccac ccacaccgga
181 attggtcaaa aagatccctc ctcccccacc caacggggag gatgaactag tggtctctta
241 cagcgccaaa gatggcgttt ccggattgcc tgagctcacc actgtcagac aaccggaaga
301 aaccaacacg gcgttcagtg tccccccact caaccaaagg gagagcaggg acgccaagga
361 gccactaact ggaacaatta ttgaaatgtg ggatggagaa atctaccatt acggcctgta
421 cgtggaacga ggtcttatac tcggtgtgca caagccaccg gcagccatca gccttgccaa
481 ggtcgagcta acaccgctct ctttgttctg gagacctgta tacacccccc agtatctcat
541 ctctccagac actcttagga gattacatgg agagtcattc ccctacactg catttgacaa
601 caattgctac gccttttgtt gttgggtatt agacctaaac gactcatggc taagcaggag
661 aatgattcag agaacaacag gtttcttcag gccgtaccag gattggaaca ggaaacccct
721 ccccactatg gatgattcca aattaaagaa ggtagccaac atattcttgt gcactttgtc
781 ttcactattc accagaccca ttaaggacat aatagggaag ttgaaacccc tcaacatcct
841 taacattctg gctacatgtg attggacctt cgcaggcata gtggaatctt taatactctt
901 agcagaactc tttggagttt tctggacacc cccagatgtg tctgcgatga tcgccccctt
961 gctaggtgat tatgaactgc aaggacctga ggaccttgca gtggagctag tcccaatagt
1021 gatggggggg ataggtttgg tgctaggatt taccaaagag aaaattggaa agatgctatc
1081 atccgctgca tccactttaa gagcttgtaa agaccttggt gcatacggac tggaaatctt
1141 aaaattggtc atgaagtggt tcttcccaaa gaaagaggaa gcaaatgaac tggctatggt
1201 gagatccatc gaggatgcag tgctagacct cgaggcaatt gaaaacaacc acatgaccac
1261 cctactcaaa gacaaagaca gcttggcaac ctacatgaga acccttgacc ttgaggagga
1321 gaaagccaga aaactctcaa ccaaatctgc ttcacccgat attgtgggca cagtcaactc
1381 tcttctggca agaatcgctg ctgcacgctc cctagtgcat cgggcgaaag aagagctctc
1441 cagcaggccg agacctgtcg ttgtgatgat atcgggaaga ccagggatag ggaaaactca
1501 ccttgccagg gagctagcca agaagatcgc ggcctccctc acaggggacc agcgtgtggg
1561 tcttatccca cgcaatggtg tcgatcactg ggacgcatac aagggcgaaa gagttgtcct
1621 atgggacgac tatggaatga gcaaccccat ccatgatgcc ctcaggttgc aggagcttgc
1681 tgacacttgc cccctcacgc taaattgtga cagaattgag aacaaaggga aagtctttga
1741 cagtgatgct ataattatca ccaccaatct ggccaaccca gcaccactgg attatgtcaa
1801 ctttgaagcg tgctcgagac gtattgactt cctcgtgtac gcagaagccc ctgaggtgga
1861 gaaggcaaag cgcgacttcc caggtcaacc tgacatgtgg aagaacgctt tcagtcctga
1921 cttctcacac ataaaactgt cattggctcc acagggtggt tttgacaaga acggcaacac
1981 cccgcatgga aaaggggtca tgaagaccct caccactggc tccctcatcg cccgagcatc
2041 agggttactc catgagaggc tagatgaata tgaactgcaa ggcccagccc tcaccacttt
2101 caactttgac cgaaacaaga tacttgcttt tagacagctt gctgctgaaa acaagtatgg
2161 gctgatggac acaatgagag ttggaaaaca gctcaaggat gtcaagacca tgtcagacct
2221 caaacaagca ctcaagaaca tcgcgatcaa gaaatgccag atagtgtaca atggtagcac
2281 ctacacactt gaggccgatg gcaagggtag tgtgaaagtt gacaaagtgc aaagtgccac
2341 tgtgcagacc aacaatgaac tagccggtgc cctacaccac ctaaggtgcg ctagaatcag
2401 atactatgtt aagtgcgtcc aggaggcact gtattccatc atccaaatcg ctggggctgc
2461 attcgtcacc acgcgcatcg ctaagcgcat gaatatacag aatctctggt ccaagccaca
2521 ggtggaagac acagaagaga tgaccaacaa agatggttgc ctaaaaccca aagatgatga
2581 agagtttgtc gtctcatccg acgacatcaa aactgagggc aagaaaggga agaacaagtc
2641 cggccgtggc aagaaacaca cagccttttc aagcaaaggg ctcagtgatg aggagtacga
2701 tgagtacaag agaatcagag aagaaaggaa tggtaagtac tccatagaag agtaccttca
2761 ggacagagac aggtactacg aggaggtggc cattgccagg gcaaccgaag aggacttctg
2821 tgaagaagaa gaggccaaaa tccggcagag aatttttaga ccaacaagga aacaacgcaa
2881 agaagagagg gcctctctcg gcttggtcac aggctctgaa atcaggaaga gaaacccaga
2941 agacttcaaa cccaagggaa agctgtgggc tgatgatgac agaagtgttg actacaatga
3001 gaaactcaac tttgaggccc caccaagcat ctggtcgcgg atagtcaact ttggttcagg
3061 ctggggcttc tgggtctccc ccagtctgtt tataacatca acccatgtca taccccaagg
3121 tgcaaaagag ttcttcggag tccctatcaa gcaaatccag atacacaaat caggtgaatt
3181 ctgccggttg agattcccaa agccaatcag aactgatgtg acgggcatga ttctagaaga
3241 aggtgcgccc gaggggaccg tggccacact gctcatcaag agaccaactg gagagctcat
3301 gcctctggca gccagaatgg ggacccatgc aaccatgaaa attcaggggc gcacagttgg
3361 agggcaaatg ggtatgctcc tgacaggatc caacgccaag agtatggacc taggcacaac
3421 accaggcgac tgcggctgcc cctacatcta caagaggggg aatgactacg tggtcatagg
3481 agtccatacg gccgctgccc gtggaggaaa caccgtcata tgtgccaccc aggggagtga
3541 gggagaagcc acacttgaag gaggtgacag taaagggaca tactgtggcg caccaatctt
3601 gggcccaggg agcgctccga aactcagcac caagactaag ttttggagat catccacaac
3661 accactccca cctggcacct acgaaccagc ctacctcggt ggcaaagacc ccagagtcaa
3721 aggtggccct tcattgcaac aagttatgag ggaccagcta aagccattca cagaacccag
3781 aggcaaacca ccaagaccaa acgtgttgga agctgccaag aaaaccatca tcaatgtcct
3841 tgagcaaaca attgatccac cccaaaaatg gtcatttgcg caagcttgcg catcccttga
3901 caaaaccacc tccagcggcc acccgcacca catgcggaaa aacgattgtt ggaatgggga
3961 gtccttcaca ggaaaattgg ctgatcaagc ctccaaggcc aacctaatgt ttgaagaggg
4021 aaagaacatg accccagtct acacaggtgc acttaaagat gagttggtaa agaccgataa
4081 agtttatggt aagatcaaga agaggcttct gtggggttca gatctggcga ccatgatacg
4141 gtgcgctcga gcttttggag gccttatgga tgaactcaag gcgcactgtg tcacacttcc
4201 tgtcagagtt ggtatgaaca tgaatgagga tggccccatc atctttgaga agcactccag
4261 atatagatat cactatgatg ctgattattc ccggtgggac tcaacacaac aaagggatgt
4321 gctagcagca gcactagaaa tcatggttaa gttctcttca gaaccacacc tggcccaggt
4381 agttgcagaa gacctccttt cccctagcgt aatggatgta ggtgactttc aaatatcaat
4441 aagtgagggt cttccctctg gggtaccttg tacctcccag tggaattcca tcgcccactg
4501 gctcctcact ctttgtgcac tctctgaagt cacggacctg tcccctgaca tcattcaggc
4561 caactccctt ttctccttct acggtgatga tgagattgta agcacagaca taaagttgga
4621 cccagagaag ctgacagcaa aactcaagga gtacgggctg aaaccaaccc gccccgacaa
4681 aactgaagga ccccttgtta tctctgaaga cctggatggc ctgacattcc tccggagaac
4741 tgtgacccgt gatccagctg gctggtttgg aaaattggaa caaagttcaa ttctcagaca
4801 aatgtactgg accaggggtc ccaaccatga agatccattt gaaacaatga taccacactc
4861 ccaaagaccc atacaattga tgtccttgct gggcgaggct gcactccatg gcccggcatt
4921 ttatagcaaa attagcaagt tagtcattgc agagttgaag gaaggtggca tggattttta
4981 cgtgcccaga caagagccaa tgttcagatg gatgagattc tcagatctga gcacgtggga
5041 gggcgatcgc aatctggctc ccagttttgt gaatgaagat ggcgtcgagt gacgccaacc
5101 catctgatgg gtccgcagcc aacctcgtcc cagaggtcaa caatgaggtt atggctctgg
5161 agcccgttgt tggtgccgcc attgcggcac ctgtagcggg ccaacaaaat gtaattgacc
5221 cctggattag aaacaatttt gtacaagccc ctggtggaga gtttacagtg tcccctagaa
5281 acgctccagg tgaaatacta tggagcgcgc ccttgggccc tgatctaaat ccctacctat
5341 cccatttggc cagaatgtac aatggttatg caggtggttt tgaagtgcag gtaattctcg
5401 cggggaacgc gttcaccgcc gggaaggtca tatttgcagc agtcccacca aattttccaa
5461 ctgaaggctt gagccccagc caggtcacta tgttccccca tatagtagta gatgttaggc
5521 aactagaacc tgtgttgatt cccttacccg atgttaggaa taatttctat cattataatc
5581 agtcaaatga ccccaccatt aagttgatag caatgttgta cacaccactt agggctaata
5641 atgctgggga tgatgtcttc acagtttctt gccgagttct cacgagacca tcccccgatt
5701 ttgatttcat atttctagtg ccacccacag ttgagtcaag aactaaacca ttctctgtcc
5761 cagttttaac tgttgaggag atgaccaatt caagattccc cattcctttg gaaaagttgt
5821 tcacgggtcc cagcagtgcc tttgttgtcc aaccacaaaa cggcaggtgc acgactgatg
5881 gcgtgctcct aggcaccacc caactgtctc ctgtcaacat ctgcaccttc agaggagatg
5941 tcacccatac cacaggtagt cgtaactaca caatgaattt ggcttctcaa aattggaaca
6001 attatgaccc aacagaagaa atcccagccc ctctaggaac tccagacttt gtggggaaga
6061 ttcaaggcgt gctcacccaa accacaagga cagatggctc aacacgcggc cacaaagcca
6121 cagtgtacac tgggagcgcc gactttgctc caaaactggg tagagttcaa tttgaaactg
6181 acacagacca tgattttgaa gctaaccaaa acacaaagtt caccccagtc ggtgtcatcc
6241 aagatggtag caccacccac cgaaatgaac cccaacagtg ggtgctccca agttactcag
6301 gcagaaatac tcctaatgtg catctggccc ccgctgtagc ccccactttt ccgggtgagc
6361 aacttctctt cttcagatcc accatgcccg gatgcagcgg ttaccccaac atggatttgg
6421 actgtctgct cccccaggaa tgggtgcagt acttctacca agaggcagcc ccagcacaat
6481 ctgatgtggc tctgctaaga tttgtgaatc cagacacagg tagggttttg tttgagtgta
6541 agcttcataa atcaggctat gttacagtgg ctcacactgg ccaacatgat ttggttattc
6601 cccccaatgg ttattttaga tttgattcct gggtcaacca gttctacacg cttgccccca
6661 tgggaaatgg aacggggcgt agacgtgcag tataatggct ggagctttct ttgctggatt
6721 ggcatctgat gtccttggct ctggacttgg ttcccttatc aatgctgggg ctggggccat
6781 caaccaaaaa gttgagtttg aaaataacag aaaattgcaa caagcatcct tccaatttag
6841 cagcaatcta caacaggctt cctttcaaca tgacaaagag atgctccaag cacaaattga
6901 ggccaccaaa aagctacaac aggaaatgat gaaagttaag caggcaatgc tcctagaagg
6961 tgggttctct gagacagatg cagcccgcgg ggcaatcaac gcccccatga caaaagcttt
7021 ggactggagc gggacaaggt actgggctcc cgatgctagg actacaacat acaatgcagg
7081 ccgcttttcc acccctcaac catcgggggc actgccagga agagctaatt ttagggatgc
7141 tgtccctgct cggggttcct ccagtaaatc ttctaactct tctactgcta cttctgtgta
7201 ctcaaatcaa actacttcaa cgagacttgg ttctacagct ggttctggta ccagtgtctc
7261 gagcctcccg tcaactgcaa ggactaggag ctgggttgag gatcaaagta gggatttgtc
7321 acctttcatg aggggggccc ataacatatc gtttgtcacc ccaccatcta gcagatcctc
7381 tagccaaggc acagtctcaa ccgtgcctaa agaggttttg gactcctgga ctggcgcttt
7441 caacacgcgc aggcagccac tcttcgctca cattcgtaag cgaggggagt cacgggcgta
7501 atgtgaaaag acaaaattga ttatctttct tttctttttc t
//