Typing tool
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Typing tool
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Complete norovirus genomes
| PV282522 | GII.4 New Orleans | |
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| GII.P4 New Orleans |
ORF1: 1..5090
ORF2: 5071..6693
ORF3: 6693..7499
LOCUS PV282522 7544 bp RNA linear VRL 28-JUL-2025
DEFINITION Norovirus GII isolate TCH10-144 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION PV282522
VERSION PV282522.1
DBLINK BioProject: PRJNA1195114
BioSample: SAMN45209627
Sequence Read Archive: SRR31712889
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7544)
AUTHORS Bhamidipati,S.V., Surathu,A., Ramani,S., Atmar,R.L., Estes,M.K.,
Muzny,D.M., Cregeen,S.J. and Doddapaneni,H.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2025) Molecular Virology and Microbiology, Baylor
College of Medicine, Alkek Center for Metagenomics and Microbiome
Research, 1 Baylor Plaza, Houston, TX 77030, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: VirMap v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7544
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="TCH10-144"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA: Houston"
/collection_date="15-Feb-2010"
/note="genotype: GII.4"
gene <1..5090
/gene="ORF1"
CDS <1..5090
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XPY62833.1"
/translation="SNDASAAAVANSNNDIAKSSSDGVLSSMAVTFKRALGARPKQPP
PREKPQRPPRPPTPELVKNIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPEESNT
AFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAKV
ELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSWLSR
RMIQRTTGFFRPYQDWNRKPLPTMDDSKIKKVANIFLCALSSLFTRPIKDIIGKIRPL
NILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVE
LVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEE
ANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSAS
PDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKRI
AASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTL
NCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRD
FPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLL
HERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVRTMPELK
QALKNVSIKKCQIVYSGCTYILESDGNGNVKVDRIQSAAVQINNELAGALHHLRSARI
RYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVENTEETTSKDGCPKPK
DDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSI
EEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGSE
IRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLFI
TSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVVT
LLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCP
YIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGSA
PTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPRGKP
PKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHVRKNDCWNGES
FTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLATMI
RCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWDSTQQ
RAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQWN
SIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLREYGL
KPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHGD
PSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFR
WMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..980
/gene="ORF1"
/product="p48"
mat_peptide 981..2078
/gene="ORF1"
/product="NTPase"
mat_peptide 2079..2615
/gene="ORF1"
/product="p22"
mat_peptide 2616..3014
/gene="ORF1"
/product="VPg"
mat_peptide 3015..3557
/gene="ORF1"
/product="Pro"
mat_peptide 3558..5087
/gene="ORF1"
/product="RdRp"
gene 5071..6693
/gene="ORF2"
CDS 5071..6693
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPY62834.1"
/translation="MKMASSDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIPGSRNYTMNLASQNWNSYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFSPKLGRVQFATDTDNDFETNQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNIHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6693..7499
/gene="ORF3"
CDS 6693..7499
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPY62835.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKTLDWNGTRYWAPDARTTTYNAGRFSTPQPSGAPPGRANLRATVPARGSSSTSS
NSSIATSVYSSQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacatc gcaaaatctt
61 caagtgacgg agtgctttct agcatggctg tcacttttaa acgagccctc ggggcgcggc
121 ctaaacagcc tcccccgagg gaaaaaccac aaagaccccc acgaccacct actccagaac
181 tggtcaaaaa tattccccct cccccaccca acggagagga tgaaatagtg gtttcttaca
241 gtgtcaaaga tggtgtctcc ggcttgcctg acctttccac cgtcaggcaa ccggaagaat
301 ctaacacggc cttcagtgtc cctccactca atcagaggga gaacagagat gctaaggagc
361 cacttactgg aacaattctg gaaatgtggg acggggaaat ctaccattat ggcctgtatg
421 tggagcgagg tcttgtacta ggtgtgcaca aaccaccagc tgccatcagc ctcgctaagg
481 ttgagctagc accactctcc ttgtactgga gacctgtgta cactcctcag tacctcatct
541 ctccagacac tctcaagaaa ttatccggag aaacgttccc ctacacagcc tttgacaaca
601 actgttatgc cttttgttgc tgggtcctgg acctaaatga ctcgtggctg agcaggagaa
661 tgatccagag aacaactggt ttcttcaggc cctaccaaga ctggaatagg aaaccccttc
721 ccactatgga tgactccaaa ataaagaagg tagctaacat attcctgtgt gctctgtcct
781 cgctgttcac cagacccata aaagatataa tagggaagat aaggcctctt aacatcctca
841 acatcttagc ctcatgtgat tggacttttg caggcatagt ggagtccctg atactcttgg
901 cagaactctt tggagttttc tggacacccc cagatgtgtc tgcgatgatt gcccccttgc
961 ttggtgacta cgagctacaa ggacctgagg accttgcagt ggagctcgtc cccgtagtga
1021 tggggggaat tggtttggtg ctaggattca ccaaagagaa gattgggaaa atgttgtcat
1081 ctgctgcgtc caccttgaga gcttgtaaag accttggtgc atatgggcta gagatcctaa
1141 agttggttat gaagtggttc ttcccgaaga aggaggaggc aaatgagttg gctatagtga
1201 ggtctatcga ggatgcagtc ctagatctcg aggcaattga aaacaaccat atgaccacct
1261 tgctcaaaga caaagacagt ctggcaacct atatgagaac acttgacctt gaggaggaga
1321 aagccaggaa actctcaacc aagtctgcct cacccgacat cgtgggcaca atcaacgccc
1381 tcctggcgag aatcgctgcc gcacgttctc tggtgcatcg agcgaaggag gagctttcca
1441 gcagaccaag acctgtagtg ctgatgatat caggcaggcc aggaataggg aagacccacc
1501 tcgctaggga agtggctaag agaatcgcag cctcccttac aggagaccag cgtgtgggcc
1561 tcatcccacg caatggcgtc gaccattggg atgcgtacaa gggggagagg gtcgtcctat
1621 gggacgatta tggaatgagc aaccctattc acgatgccct caggctgcaa gaactcgctg
1681 acacttgccc cctcactcta aactgtgaca ggattgaaaa taaaggaaaa gtctttgaca
1741 gcgatgtcat cattatcacc actaatctgg ccaacccagc accactggac tatgtcaact
1801 ttgaagcatg ctcgaggcgc atcgacttcc tcgtgtatgc agaagcccct gaagtcgaaa
1861 aggcgaagcg tgacttccca ggccagcctg acatgtggaa gaacgctttc agctctgatt
1921 tctcacacat aaaactagca ctggccccac agggtggttt cgacaagaac gggaacaccc
1981 cgcacggaaa gggcgtcatg aagactctca ccactggctc ccttattgcc cgggcatcag
2041 ggctactcca tgagaggtta gatgaatttg aactacaggg cccagctctc accaccttca
2101 atttcgatcg caataaagtg cttgccttta gacagcttgc tgctgaaaat aaatatggat
2161 tgatggacac aatgagggtt gggaaacagc tcaaggatgt cagaaccatg ccagaactca
2221 aacaagcact caagaatgtc tcaatcaaga agtgtcaaat agtgtatagt ggttgcacct
2281 acatacttga gtctgatggc aatggcaatg tgaaagttga cagaatccaa agcgccgccg
2341 tgcagatcaa caatgagctg gctggtgccc tgcaccattt gaggagcgcc agaatcagat
2401 actatgtcaa gtgtgtccag gaggccctgt attccatcat tcaaattgct ggggctgcat
2461 ttgtcaccac gcgcattgcc aagcgcatga acatacaaaa cctatggtcc aagccacaag
2521 tggaaaacac agaggagact accagcaagg acgggtgccc aaaacctaag gatgatgagg
2581 agtttgtcat ttcatccgac gatatcaaaa ctgagggtaa gaaagggaag aacaagactg
2641 gccgcggcaa gaagcacaca gcattttcaa gcaaaggcct cagtgatgaa gagtacgatg
2701 agtacaagag gattagagaa gaaaggaatg gcaagtactc catagaagag taccttcagg
2761 acagggacaa atactatgag gaggtggcca ttgccagggc gactgaggaa gacttctgtg
2821 aagaggagga ggccaagatc cggcaaagga tctttaggcc aacaaggaaa caacgcaagg
2881 aggaaagagc ctctctcggt ctggtcacag gctctgaaat taggaaaaga aacccagatg
2941 acttcaaacc caaggggaaa ttgtgggctg acgatgacag gagtgtggac tacaatgaga
3001 aactcagttt tgaggccccg ccaagcatct ggtcgagaat agtcaacttt ggttcaggct
3061 ggggattctg ggtctccccc agtctgttca taacatcaac ccatgtcata ccccagggcg
3121 caaaggagtt ctttggagtc cccatcaaac aaatacaggt acacaagtca ggcgagttct
3181 gccgcttgag attcccaaaa ccaatcagga ctgatgtgac gggcatgatc ttagaagaag
3241 gcgcacctga gggcaccgtg gtcacactac tcatcaaaag gtccactggg gaactcatgc
3301 ccctagcagc taggatgggg acccatgcga ccatgaagat ccaagggcgc actgttggag
3361 gccagatggg catgcttctg acaggatcca acgccaagag catggacctg ggtactacac
3421 caggtgattg tggctgcccc tatatctaca agagaggtaa tgactatgtg gtcattggag
3481 tccacacggc tgccgcacgt gggggaaaca ctgtcatatg tgccacccag gggagtgaag
3541 gagaggctac acttgaaggt ggtgacaaca aggggacata ctgtggtgca ccaatcctag
3601 gcccagggag tgccccaaca cttagcacca agaccaaatt ctggagatcg tccacagcat
3661 cactcccacc tggcacctat gaaccagcct atcttggtgg caaggaccct agagtcaagg
3721 gtggcccttc actgcagcaa gtcatgaggg aacagttgaa gccatttaca gagccaaggg
3781 gcaagccacc aaaaccaagt gtattagaag ctgccaagaa gaccatcatc aatgtccttg
3841 agcaaacaat tgatccacct gagaaatggt cgttcgcaca agcttgcgcg tcccttgaca
3901 agaccacttc cagtggtcat ccgcaccacg tgcggaaaaa cgactgctgg aacggggagt
3961 ccttcacagg caagctggca gaccaggctt ccaaggccaa cctgatgttt gaagaaggga
4021 agaacatgac cccagtctac acagctgcgc tcaaggatga gttagttaaa actgacaaaa
4081 tttatggtaa gatcaagaag agacttctct ggggctcgga cttggcgacc atgatccggt
4141 gtgctcgagc attcggaggc ctaatggatg aactcaaagc acactgtgtc acgcttccca
4201 ttagagttgg catgaatatg aatgaggatg gccccatcat cttcgagagg cattccaggt
4261 acacatatca ctatgatgct gattactctc gatgggattc aacacaacag agagccgtgc
4321 tggcagcagc tctagaaatc atggttaaat tctccccaga accacatttg gctcaggtag
4381 tcgcggaaga ccttctttct cctagcgtgg tggacgtggg cgacttcaca atatcaatca
4441 acgagggtct tccctctggg gtgccctgca cctcccaatg gaactccatc gcccactggc
4501 ttctcactct ctgtgcgctc tccgaagtca caaatctatc ccctgatacc atacaggcta
4561 actccctctt ctctttttat ggtgatgatg aaattgttag cacagacata aaattggacc
4621 cagagaaatt gacagcaaag ctcagagaat atgggttaaa accaacccgc cctgacaaaa
4681 ctgaagggcc ccttgtcatc tctgaagacc tgaatggcct aactttcctg cggagaactg
4741 tgacccgcga cccagctggt tggtttggaa aactggagca gagttcaata ctcaggcaaa
4801 tgtactggac taggggtccc aaccatggag acccatctga aacaatgatt ccacactccc
4861 aaagacccat acaattgatg tccctactgg gggaggccgc tctccacggc ccagcctttt
4921 acagcaaaat cagcaagttg gtcattgcag agctaaaaga aggtggcatg gatttttacg
4981 tgcccagaca agagccaatg ttcagatgga tgagattctc agatctgagc acgtgggagg
5041 gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgagtga cgccaaccca
5101 tctgatgggt ccacagccaa cctcgtccca gaggtcaaca atgaggttat ggctttggag
5161 cccgtagttg gtgccgccat tgcggcacct gtagcgggcc aacaaaatgt aattgacccc
5221 tggattagaa acaattttgt acaagcccct ggtggagagt ttacagtatc ccctagaaac
5281 gctccaggtg aaatactatg gagcgcgccc ttaggtcctg atctgaatcc ctacctttcc
5341 catttggcca gaatgtacaa tggttatgca ggtggttttg aagtgcaggt aatcctcgcg
5401 gggaacgcgt tcaccgccgg gaaaatcata tttgcagcag tcccaccaaa tttcccaact
5461 gaaggtttga gccccagcca ggtcactatg ttcccccaca taatagtaga tgttaggcaa
5521 ttggaacctg tgttgatccc cttacccgat gttaggaata atttctacca ttataatcaa
5581 tcaaatgacc ccaccatcaa attgatagca atgttgtaca caccacttag ggctaataat
5641 gccggggacg atgtcttcac agtttcttgt cgagttctca cgagaccatc ccccgatttt
5701 gatttcatat ttttggtgcc acccacagtt gaatcaagaa ctaaaccttt ctctgtccca
5761 gttttaactg ttgaggagat gaccaattca aggttcccca ttcctttgga aaagttgttc
5821 acgggcccta gtagtgcctt tgttgttcaa ccacaaaatg gcaggtgcac gactgatggc
5881 gtgctcctag gtactaccca actgtcccct gtcaacatct gcaccttcag aggggatgtc
5941 acccatattc caggcagtcg taactacaca atgaatttgg cctcccaaaa ttggaacagt
6001 tacgatccaa cagaagaaat cccagcccct ctaggaactc cagatttcgt ggggaagatt
6061 caaggtgtgc tcacccaaac cacaaggaca gatggctcta cccgcggcca caaagctaca
6121 gtgtacactg ggagcgccga cttttctcca aaactgggta gagttcaatt tgccactgac
6181 acagacaatg attttgaaac taaccaaaac acaaagttca ccccagtcgg tgttatccag
6241 gatggtagta ccacccaccg aaatgaaccc caacaatggg tgctcccaag ttactcaggc
6301 agaaacattc ataatgtgca cctggccccc gctgtagccc ccactttccc gggcgagcag
6361 ctcctcttct tcagatctac tatgcccgga tgcagcgggt accccaacat ggatttggac
6421 tgtctgctcc cccaggaatg ggtgcagtac ttctaccagg aggcagcccc agcacaatct
6481 gatgtggctc tgttaagatt tgtgaatcca gacacaggta gggttttgtt tgagtgtaag
6541 cttcataaat caggctatgt tacagtggct cacactggcc aacatgattt ggttatcccc
6601 cccaatggtt attttagatt tgattcctgg gtcaaccagt tctacacact tgcccccatg
6661 ggaaatggga cggggcgtag acgtgcatta taatggctgg agctttcttt gctggattgg
6721 catctgacgt ccttggctct ggacttggtt ccctaatcaa tgctggggct ggggccatca
6781 accaaaaagt tgaatttgaa aataacagaa aattgcaaca agcctccttc caatttagta
6841 gcaatctaca acaggcttcc tttcagcatg acaaagagat gctccaagca caaattgagg
6901 ccaccaaaaa gttgcaacag gaaatgatga gagttaaaca agcaatgctc ctagagggtg
6961 gattctctga gacagatgca gcccgtgggg caatcaacgc ccccatgaca aaaactttgg
7021 actggaacgg gacaaggtac tgggctcccg atgctaggac tacaacatat aatgcaggcc
7081 gcttttccac ccctcaaccc tcgggggcac caccaggaag agctaatctt agggctactg
7141 tccccgcccg gggttcctcc agcacgtctt ctaactcttc tattgctact tctgtgtatt
7201 caagtcaaac cacctcaacg agacttggtt ctacagctgg ttctggtacc agtgtctcga
7261 gcctcccgtc aactgcaagg actaggagct gggttgagga tcaaaatagg aatttgtcac
7321 ctttcatgag gggggcccac aacatctcgt ttgtcacccc accatctagc agatcctcta
7381 gccaaggcac agtctcaacc gtgcccaaag aagttttgga ctcctggact ggcgctttca
7441 acacgcgcag gcagcctctc ttcgctcaca ttcgcaagcg aggggagtca cgggcgtaat
7501 gtgaaaagac aaaattgatt atctttcttt tctttagtgt cttt
//