Typing tool
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Typing tool
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Complete norovirus genomes
| PV282521 | GII.4 Henry | |
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| GII.P4 Apeldoorn |
ORF1: 1..5093
ORF2: 5074..6696
ORF3: 6696..7502
LOCUS PV282521 7548 bp RNA linear VRL 28-JUL-2025
DEFINITION Norovirus GII isolate TCH02-186 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION PV282521
VERSION PV282521.1
DBLINK BioProject: PRJNA1195114
BioSample: SAMN45209635
Sequence Read Archive: SRR31712891
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7548)
AUTHORS Bhamidipati,S.V., Surathu,A., Ramani,S., Atmar,R.L., Estes,M.K.,
Muzny,D.M., Cregeen,S.J. and Doddapaneni,H.
TITLE Direct Submission
JOURNAL Submitted (14-MAR-2025) Molecular Virology and Microbiology, Baylor
College of Medicine, Alkek Center for Metagenomics and Microbiome
Research, 1 Baylor Plaza, Houston, TX 77030, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: VirMap v. 1
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7548
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="TCH02-186"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA: Houston"
/collection_date="13-Mar-2002"
/note="genotype: GII.4"
gene <1..5093
/gene="ORF1"
CDS <1..5093
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="XPY62830.1"
/translation="ASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARPKQP
PPREIPQRPPRPPTPELVKKIPPPPPNGEDEIVVSYSVKDGVSGLPELSTVRQPEEAN
TAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAK
VELTPLSLFWRPVYTPQYLISPDTLKKLHGETFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCALSSLFTRPIKDIIGKLRP
LNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKE
EANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSA
SPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVAKR
IAASLTGDQRVGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLT
LNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKR
DFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGL
LHERLDEFELQGPTLTTFNFDRNKVLAFRQLAAENKYGLMDTMKVGRQLKDVRTMPEL
KQALKNISIKKCQIVYSGCTYTLESDGKGNVKVDRVQSASVQTNNELTGALHHLRCAR
IRYYVRCVQEALYSIIQIAGAAFVTTRIVKRMNIQDLWSKPQVENTEEATNKDGCPKP
RDDEEFVISSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTKKQRKEERASLGLVTGS
EIRKRNPDDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLF
ITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVV
TLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGPGS
APKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCWNGE
SFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLATM
IRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYRYHYDADYSRWDSTQ
QRAVLAAALEVMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTNLSPDIIQANSHFSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHE
DPSETMIPHSQRPIQLMSLLGEAALHGPTFYSKISKLVIAELKEGGMDFYVPRQEPMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..983
/gene="ORF1"
/product="p48"
mat_peptide 984..2081
/gene="ORF1"
/product="NTPase"
mat_peptide 2082..2618
/gene="ORF1"
/product="p22"
mat_peptide 2619..3017
/gene="ORF1"
/product="VPg"
mat_peptide 3018..3560
/gene="ORF1"
/product="Pro"
mat_peptide 3561..5090
/gene="ORF1"
/product="RdRp"
gene 5074..6696
/gene="ORF2"
CDS 5074..6696
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPY62831.1"
/translation="MKMASSDASPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFTVPILTVEEMTNSRFPIPLEKLFTGPSGAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHIAGTHDYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRGDGSTRGHKATVSTGSVHFTPKLGSVQFTTDTNNDLETGQNTKFTPVGVVQDG
NSAHQNEPQQWVLPNYSGRTGHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLD
CLLPQEWVLHFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGPHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6696..7502
/gene="ORF3"
CDS 6696..7502
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPY62832.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQGMMEVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRINPRAPAPAQGSSSTPS
STSTATSVYSNQTVSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 tggcgtctaa cgacgcttcc gctgccgctg ttgctaacag caacaacgac accgcaaaat
61 cttcaagtga cggagtgctt tctagcatgg ctgtcacttt taaacgagcc ctcggggcgc
121 ggcctaaaca gccccccccg agggaaatac cacaaagacc cccacgacca cctactccag
181 aactggtcaa aaagatcccc cctcccccgc ctaacggaga ggatgagata gtggtttctt
241 atagtgtcaa agatggtgtt tccggtttgc ctgagctttc caccgtcagg caaccggaag
301 aagctaatac ggccttcagt gtccccccac tcaatcagag ggagaataga gatgctaagg
361 agccactgac tggaacaatt ctggaaatgt gggatggaga aatctaccat tatggcctgt
421 atgtggagcg aggtcttgta ctaggtgtgc acaagccacc agctgccatt agcctcgcca
481 aggtcgaact aacaccactc tccttgttct ggagacctgt gtatactcct cagtacctca
541 tctctccaga cactctcaag aaattacatg gagaaacgtt tccctacaca gcctttgaca
601 acaattgcta tgccttttgt tgctgggtcc tggacctaaa cgactcgtgg ctgagtagga
661 gaatgatcca gagaacaact ggcttcttca gaccctacca agattggaat aggaaacccc
721 tccccactat ggatgattcc aaattaaaga aggtagctaa catattcctg tgtgccctgt
781 cttcgctatt caccaggccc ataaaagaca taatagggaa gctaaggcct cttaacatcc
841 tcaacatctt ggcttcatgt gattggactt tcgcaggcat agtggagtcc ttgatactct
901 tggcagagct ctttggagtt ttctggacac ccccagatgt gtctgcgatg attgccccct
961 tactcggtga ttacgagttg caaggacctg aagaccttgc agtggagctc gtccctgtag
1021 tgatgggggg aattggtctg gtgctgggat tcaccaaaga gaagattgga aaaatgttgt
1081 catctgctgc atccaccttg agggcttgta aagatcttgg tgcatatggg ctagagatcc
1141 taaagttggt catgaagtgg ttcttcccga agaaagagga agcaaatgaa ctggctatgg
1201 tgagatccat cgaggatgca gtgttggacc tcgaggcaat cgaaaacaac catatgacca
1261 ccttgctcaa ggacaaagat agtctggcaa cctacatgag aacccttgac ctcgaggaag
1321 agaaagccag aaaactctca accaagtctg cttcacctga catcgtgggc acaatcaacg
1381 cccttttggc gagaatcgct gctgcacgtt ccctggtgca tcgagcgaag gaggaacttt
1441 ccagcagacc aagacctgta gtcttaatga tatcaggcag accaggaata gggaagaccc
1501 accttgctag ggaagtggct aagagaatcg cagcctccct cacaggagac cagcgtgtag
1561 gcctcgtccc acgcaatggc gtcgatcact gggatgcgta caagggggag agggtcgtcc
1621 tatgggacga ctatggaatg agcaatccca tccacgacgc cctcaggttg caagaactcg
1681 ctgacacttg ccccctcact ctaaactgtg acaggattga gaataaagga aaggtttttg
1741 acagcgatgt catcattatc actactaatc tagctaaccc agcaccactg gactatgtca
1801 actttgaagc atgctcgagg cgtatcgatt tcctcgtgta tgcagaagcc cctgaagtcg
1861 aaaaggcgaa gcgtgacttc ccaggccaac ctgacatgtg gaagaacgct tttagttctg
1921 atttctcaca cataaaactg acactggctc cacagggtgg ctttgataag aacgggaaca
1981 ccccacacgg gaagggcgtc atgaagactc tcactaccgg ctcccttatt gcccgggcat
2041 cagggctact ccatgagagg ctagatgaat ttgaactaca gggcccaact ctcaccacct
2101 tcaactttga tcgcaacaaa gtgcttgcct ttaggcagct tgctgctgaa aacaaatatg
2161 ggttgatgga cacaatgaaa gttgggaggc agctcaagga tgtcagaacc atgccagaac
2221 ttaaacaagc actcaagaat atctcaatca agaagtgcca gatagtgtac agtggttgca
2281 cctacacact tgagtctgat ggcaagggca atgtgaaagt tgacagagtt cagagcgcct
2341 ccgtgcagac caacaatgag ctgactggcg ccctgcacca cctaaggtgc gccagaatca
2401 ggtactatgt caggtgtgtt caggaggccc tgtattccat catccagatt gctggggccg
2461 catttgtcac cacgcgcatc gtcaagcgta tgaacataca agacctatgg tccaagccac
2521 aagtggaaaa cacagaggag gctaccaaca aggacgggtg cccaaaaccc agagatgatg
2581 aggagttcgt catttcgtcc gacgacatta aaactgaggg taagaaaggg aagaacaaga
2641 ccggccgtgg caagaaacac acagccttct caagcaaagg tctcagtgat gaggagtacg
2701 atgagtacaa gaggattaga gaagaaagga atggcaagta ctccatagaa gagtaccttc
2761 aggacaggga caaatactat gaggaggtgg ccattgccag ggcgaccgag gaagacttct
2821 gtgaagagga ggaggccaag atccggcaaa ggatcttcag gccaacaaag aaacaacgca
2881 aggaagaaag agcttctctc ggtttggtca caggttctga aattaggaaa agaaacccag
2941 atgatttcaa gcccaagggg aaactgtggg ctgacgatga cagaagtgtg gactacaatg
3001 agaaactcag ttttgaggcc ccaccaagca tctggtcgag gatagtcaac tttggttcag
3061 gttggggctt ctgggtctcc cccagtctgt tcataacatc aacccacgtc ataccccagg
3121 gcgcaaagga attctttgga gtccccatca aacaaattca ggtacacaag tcaggcgaat
3181 tctgtcgctt gagattcccg aaaccaatca ggactgatgt gacgggcatg atcttagaag
3241 aaggtgcgcc cgaaggcacc gtggtcacac tactcatcaa aaggtctact ggagaactca
3301 tgcccctagc agctagaatg gggacccatg caaccatgaa aattcaaggg cgcactgttg
3361 gaggtcaaat gggcatgctt ctgacaggat ccaatgccaa aagcatggat ctaggcacca
3421 caccaggtga ttgcggctgt ccctacatct acaagagagg aaatgactat gtggtcattg
3481 gagtccacac ggctgccgct cgtgggggaa acactgtcat atgtgccact caggggagtg
3541 agggggaggc tacacttgaa ggtggtgaca gtaagggaac atattgtggt gcgccaatcc
3601 taggcccagg gagtgcccca aaacttagca ccaaaaccaa attctggaga tcgtccacag
3661 caccactccc acctggcacc tatgaaccag cctatcttgg tggcaaggac cccagagtca
3721 agggtggccc ttcgttgcag caagtcatga gggatcagct gaaaccattt acagagccca
3781 ggggtaagcc accaaagcca agtgtgttag aagctgccaa gaaaaccatc atcaatgtcc
3841 ttgaacaaac aattgaccca cctgagaaat ggtcgttcgc acaagcttgc gcgtccctcg
3901 acaagaccac ttctagtggc catccgcacc acatgcggaa aaacgactgc tggaacgggg
3961 aatccttcac aggcaagctg gcagaccagg cttccaaggc caacctgatg ttcgaagaag
4021 ggaagaacat gaccccagtc tacacaggtg cgcttaagga tgaattagtc aaaactgaca
4081 aaatttatgg taagatcaag aagaggcttc tctggggttc ggatttagcg accatgatcc
4141 ggtgtgctcg agcattcgga ggcctaatgg atgaactcaa agcacactgt gttacacttc
4201 ctatcagagt tggtatgaat atgaatgagg atggccccat catcttcgag aggcattcca
4261 ggtacagata ccactatgat gctgattact ctcggtggga ttcaacacaa cagagagccg
4321 tgttggcagc tgctctagaa gtcatggtta aattctcctc agaaccacat ttggctcagg
4381 tagtcgcaga agaccttctt tctcctagcg tggtggatgt gggtgacttc acaatatcga
4441 tcaacgaggg tcttccctct ggggtgccct gcacctccca atggaactcc atcgcccact
4501 ggcttctcac tctctgtgcg ctctctgaag ttacaaattt gtcccctgac atcatacagg
4561 ctaattccca cttctccttt tatggtgatg acgaaattgt tagtacagac ataaaattag
4621 acccagagaa gttgacagca aaacttaagg aatatggatt gaaaccaacc cgccctgata
4681 agactgaagg acctcttgtt atctctgaag acttaaatgg tctgactttc ctgcggagaa
4741 ctgtgacccg cgacccagct ggttggtttg gaaaactgga gcagagctca atactcaggc
4801 aaatgtactg gactagaggc cccaaccatg aagacccatc tgaaacaatg attccacact
4861 cccaaagacc catacaattg atgtccctac tgggagaggc cgcactccac ggcccaacat
4921 tctacagcaa aatcagcaag ttagtcattg cagagctaaa agaaggtggt atggattttt
4981 acgtgcccag acaagagcca atgttcagat ggatgagatt ctcagatctg agcacgtggg
5041 agggcgatcg caatctggct cccagttttg tgaatgaaga tggcgtcgag tgacgccagc
5101 ccatctgatg ggtccacagc caacctcgtc ccagaggtca acaatgaggt tatggctttg
5161 gagcccgttg ttggtgccgc aattgcggca cctgtagcgg gccaacaaaa tgtaattgac
5221 ccctggatta gaaataattt tgtacaagcc cctggtggag agttcacagt atcccctaga
5281 aacgctccag gtgaaatact atggagcgcg cccttgggcc ctgatctgaa tccctacctt
5341 tctcatttgg ccagaatgta caatggttat gcaggtggtt ttgaagtgca ggtaattctc
5401 gcggggaacg cgttcaccgc cgggaaaatc atatttgcag cagtcccacc aaatttccca
5461 actgaaggct tgagccccag ccaggtcact atgttccccc atataatagt agatgttagg
5521 caactggaac ctgtgttgat tcccttacct gatgtcagga ataatttcta tcactataat
5581 cagtcaaatg accccaccat taaactgata gcaatgctgt acacaccact tagggctaat
5641 aatgctgggg atgatgtctt cacagtctct tgccgagtcc tcacgaggcc atcccctgat
5701 tttgatttta tatttttggt gccacccaca gttgagtcaa gaaccaaacc attcaccgtc
5761 ccaattttaa ctgttgagga gatgaccaat tcaagattcc ccattccttt ggaaaagttg
5821 ttcacgggtc ccagcggtgc ctttgttgtt caaccacaaa atggcagatg cacgactgat
5881 ggcgtgctct taggtactac ccaactgtct cctgttaaca tctgcacttt cagaggggat
5941 gtcacccaca ttgcaggcac tcatgattat acaatgaatt tggcttctca aaattggaac
6001 aattacgacc caacagaaga aatcccagcc cctctgggaa ctccagattt cgtgggaaag
6061 atccaaggcg tgctcactca aaccacaagg ggagatggct cgacccgtgg ccacaaagcc
6121 acagtgagca ctgggagtgt ccactttact ccaaagctgg gcagtgttca attcaccact
6181 gacacaaaca atgatcttga aactggccaa aacacgaaat tcaccccagt cggtgtcgtc
6241 caggatggta atagtgccca ccaaaatgaa ccccaacaat gggtgctccc aaattactca
6301 ggtagaactg gccataatgt acacctagcc cctgccgtag cccccacttt tccgggtgag
6361 caacttctct tcttcaggtc cactatgccc ggatgcagcg ggtatcccaa catgaatttg
6421 gattgcctac tcccccagga atgggtgctg cacttctacc aagaggcagc tccagcacaa
6481 tctgatgtgg ctctgctgag atttgtgaat ccagacacag gtagggtcct gtttgagtgc
6541 aaacttcata aatcaggcta tgtcacagtg gctcacactg gcccgcatga tttggtcatc
6601 ccccccaatg gctacttcag atttgattcc tgggttaacc aattctacac gcttgccccc
6661 atgggaaatg gagcggggcg tagacgtgcg ttataatggc tggagctttc tttgctggat
6721 tggcatctga tgtccttggc tctggacttg gttccctaat caatgctggg gctggggcca
6781 tcaaccaaaa agttgaattt gaaaataaca gaaaattgca acaagcttcc tttcaattta
6841 gcagcaatct acaacaggct tcctttcaac atgataaaga gatgctccaa gcacaaattg
6901 aggccactaa aaagttgcaa cagggtatga tggaagttaa acaggcaatg ctcttagagg
6961 gtggattctc tgaaacagat gcagcccgtg gggcaatcaa cgcccccatg acaaaggctt
7021 tggattggag cggaacaagg tactgggctc ctgatgctag gactacaaca tacaatgcag
7081 gccgcttttc cacccctcaa ccttcggggg cactgccagg aagaattaat cccagggctc
7141 ctgcccccgc tcagggctcc tccagcacac cctctagtac ttctactgct acttctgtgt
7201 attcaaatca aactgtttca acgagacttg gttctacagc tggttctggc accagtgtct
7261 cgagtctccc gtcaactgca aggactagga gctgggttga ggatcaaaac aggaatttgt
7321 cacctttcat gaggggggct cacaacatat cgttcgtcac cccaccatct agtagatctt
7381 ctagccaagg cacagtctca accgtgccta aagaaatttt ggactcctgg actggcgctt
7441 tcaacacgcg caggcagcct ctcttcgctc acattcgtaa gcgaggggag tcacgggtgt
7501 aatgtgaaaa gacaaaattg attatctttc ttttctttag tgtctttt
//