Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| PV266776 | GII.4 Wichita | |
|
|---|---|---|---|
| GII.P4 New Orleans |
ORF1: 1..5110
ORF2: 5091..6713
ORF3: 6713..7522
LOCUS PV266776 7573 bp RNA linear VRL 17-MAR-2025
DEFINITION Norovirus GII isolate Hu/GII.4 Wichita[P4]/Houston3001/2023/USA
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PV266776
VERSION PV266776.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7573)
AUTHORS Chhabra,P., Montmayeur,A.M., Bartlett,E., Boom,J. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2025) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: 454; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7573
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.4 Wichita[P4]/Houston3001/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="26-Nov-2023"
/note="genotype: GII.4 Wichita[P4]"
gene <1..5110
/gene="ORF1"
CDS <1..5110
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XPT11017.1"
/translation="ASNDASAAAVANSNNDIAKSSSDGVLSSMAVTFKRALGAKPKQP
PPREKQQQQQQQQKPPRPSTPELVKCIPPPPPNGEDEVVVSYSVKDGVSGLPDLTTVR
QPEESNTAFSVPPLNLRENKDAKEPLTGTILEMWDGEIYHYGLYVDRGLVLGVHKPPA
AISLAKVELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLNRRMIQRTTGFFRPYQDWNRKPLPTMDDSKMKKVANIFLCALSSLFTRPIKDI
IGKIRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQG
PEDIAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKW
FFPKKEEKNELAMVRAIEDAVLDLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARK
LSTKSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLA
REVAKRIASSLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELA
DTCPLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPE
VEKAKRDFPGQPDMWKNAFSPDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLI
ARASGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDV
KTMSELRQALKNVSIKKCQIVYSGNTYILESDGKGNVKVDKVQSVAVQVNNELAGALH
HLRSARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQLEDTEETASK
DGCPKPKDDEEFVVSSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDKYYEELAIARATEEDFCEEEEVKIRQRIFRPTRKQRKEERASL
GLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFW
VSPSLFITSTHVIPHGVKEFFGVPIKQIQIHKSGEFCRLRFPRPIRTDVTGMILEEGA
PEGTVASLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPF
TEPRGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHVRKN
DYWNGESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLATMVRCARAFGGLMDELKAHCITLPVRVGMNMNEDGPIIFEKHSRYAYHYDADYS
RWDSTQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTA
KLREYGLKPTRPDKTEGPLVVSEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWT
RGPNHGDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVP
RQEPMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2635
/gene="ORF1"
/product="p22"
mat_peptide 2636..3034
/gene="ORF1"
/product="VPg"
mat_peptide 3035..3577
/gene="ORF1"
/product="Pro"
mat_peptide 3578..5107
/gene="ORF1"
/product="RdRp"
gene 5091..6713
/gene="ORF2"
CDS 5091..6713
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPT11018.1"
/translation="MKMASSDASPSNGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGSVTHISGSRNWTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRSDGSTRGHTATVLTGSADFSPKLGRVQFATDTDNDFETNQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRGTNNVHLAPAVAPTFPGEQLLFFRSTLPGCSGYPNLDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6713..7522
/gene="ORF3"
CDS 6713..7522
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPT11019.1"
/translation="MAGALFAGMASDVLGSGLSSLINAGAGAINQKIDFDNNRKLQEA
SFQFSSNLQQASFKHDQDMLQAQIEATKKLQQEMMRVKQSMLLEGGFSETDAARGAIN
APMTKVLDWSGTRYWAPEARTTTYNAGRFSTPQSSGAPPGRANLRAATPARGSSSNTP
SISSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHN
ISFVTPPSSRSSSQGTVSTVPKEILDSWTSAFNTHRQPLFAHIRKRGESRV"
ORIGIN
1 ggcgtctaac gacgcttccg ctgccgctgt tgctaacagc aacaacgaca tcgcaaaatc
61 ttcaagtgac ggagtgcttt ctagcatggc tgtcactttt aaacgagccc tcggggcgaa
121 gcctaaacag cctcccccga gggaaaaaca acaacaacaa caacaacaac aaaaaccccc
181 acgaccatcc actccagaac tggtcaaatg tattccccct cccccaccca acggggagga
241 tgaagtggtg gtctcttaca gtgttaaaga tggtgtttct ggcctgcctg accttaccac
301 cgttaggcag ccagaagaat ctaacacggc ctttagcgtc cctccactca acctaaggga
361 gaacaaagat gccaaggagc cacttactgg aacaattctg gaaatgtggg acggggaaat
421 ttaccactat ggcctgtatg tggaccgagg tctcgtacta ggtgtacaca aaccaccagc
481 tgccattagc ctcgccaagg ttgagctagc accactctcc ttgtactgga gacctgtgta
541 cactcctcag tacctcatct caccggacac tctcaagaag ctgtccggag agactttccc
601 ctacacagcc tttgacaaca actgttatgc cttttgctgc tgggtcctgg acctaaatga
661 ctcatggctg aacaggagaa tgatccagag aacaaccggt ttcttcagac cctaccaaga
721 ctggaatagg aaaccccttc ccaccatgga tgactccaaa atgaagaagg tagctaacat
781 tttcctgtgt gctctgtcct cactgttcac cagacccata aaggacataa tagggaagat
841 aaggccactc aacatcctca acatcctggc ctcatgtgat tggacttttg caggcatagt
901 agaatccctg atactcttgg cagaactctt tggagtcttc tggacacccc cagatgtgtc
961 tgcgatgatt gcccccttac tcggcgatta cgagctgcaa ggacctgaag acattgcagt
1021 agagcttgtc cccgtggtga tgggggggat tggtttggtg ctgggattca ccaaagagaa
1081 gattgggaaa atgttatcat ctgctgcatc cacattaaga gcttgtaaag accttggtgc
1141 atatgggctg gagatcctaa agctggttat gaagtggttc ttcccgaaga aggaggagaa
1201 aaatgagctg gctatggtga gggctatcga ggatgcagtc ctggacctcg aggcaattga
1261 aaacaaccat ttgaccacct tgcttaagga caaagacagt ctggcaacct atatgaggac
1321 ccttgacctt gaggaggaga aagccaggaa actctcaacc aagtctgctt cacctgacat
1381 cgtgggcaca atcaacgccc tcctggcgag aatcgccgcc gcacgctctc tggtacaccg
1441 agcgaaggag gagctctcca gcagaccaag acctgtggtg ctgatgatct caggcaggcc
1501 gggaatagga aagacccatc tcgccaggga agtggctaag agaatcgcat cctccctcac
1561 aggggaccag cgtgtgggcc tcattccacg caacggcgtc gaccactggg atgcgtacaa
1621 aggggagagg gtcgtcctat gggacgacta tggaatgagc aaccctattc acgacgccct
1681 caggttgcaa gaactcgccg acacctgtcc cctcacccta aattgtgaca ggattgaaaa
1741 caaagggaag gtctttgaca gcgatgtcat cattatcacc accaacctgg ccaacccagc
1801 accactggac tatgtcaact ttgaagcatg ttcgaggcgc atcgacttcc tcgtgtatgc
1861 agaagcccct gaggtcgaaa aggcgaagcg tgacttccca ggccagcctg acatgtggaa
1921 gaacgctttc agtcctgatt tctcacacat aaagttaaca ttggccccac agggtggttt
1981 tgacaaaaac gggaacaccc cacacggaaa gggcgtcatg aagactctca ccactggttc
2041 cctcattgcc cgggcatcag ggttactcca tgagagatta gacgaatttg aactacaggg
2101 cccagctctc accaccttca atttcgatcg caataaggtg cttgccttca gacagcttgc
2161 tgcagaaaac aaatatggac tgatggacac aatgagggtc gggaaacaac tcaaggatgt
2221 caaaaccatg tcagaactca gacaagcact caagaatgtc tcaatcaaga agtgccaaat
2281 agtgtatagt ggtaacacct acatacttga gtctgatggc aagggcaacg tgaaagttga
2341 caaagttcaa agcgtcgctg tgcaggtcaa caatgagctg gccggcgccc tgcaccactt
2401 gaggagcgcc agaatcaggt actatgtcaa gtgtgtccag gaggccctgt attccatcat
2461 tcaaattgct ggagctgcat tcgtcaccac gcgcattgcc aaacgcatga acatacaaaa
2521 cctatggtcc aaaccacaat tggaagacac agaggaaact gccagcaagg acggatgccc
2581 aaaacccaag gatgatgagg agtttgtcgt ttcatccgac gacatcaaaa ctgagggcaa
2641 gaaggggaag aataagactg gccgtggcaa gaaacacaca gcattttcaa gcaaaggcct
2701 cagtgatgaa gagtacgatg agtacaagag gatcagggaa gaaaggaacg gcaagtactc
2761 catagaagag taccttcagg acagggacaa atactatgaa gaattggcca ttgccagggc
2821 gactgaggaa gacttctgcg aagaggagga ggtcaagatc cggcaaagga tcttcaggcc
2881 aacaaggaaa caacgcaagg aggaaagagc ttctctcggc ctggtcacag gctctgaaat
2941 tagaaagagg aacccagaag acttcaagcc caagggaaaa ctgtgggctg acgatgacag
3001 gagtgtggac tacaatgaaa agctcagctt tgaggccccg ccaagcatct ggtcaagaat
3061 agtcaatttt ggttcaggtt ggggattctg ggtctcccct agtctgttta taacatcaac
3121 ccatgtcata ccccatggtg taaaagaatt ctttggagtc cccatcaaac aaatacagat
3181 acacaaatca ggcgagttct gtcgcttgag gttcccaaga ccaatcagga ctgatgtgac
3241 gggcatgatc ttagaagaag gagcacctga gggcaccgtg gcctcattac tcatcaaaag
3301 acccactggg gaactcatgc ccctagcagc taggatgggg acccacgcca ccatgaagat
3361 tcaagggcgc accgttggag gccagatggg catgctacta acaggatcca acgccaagag
3421 catggacctg ggtaccacac caggtgattg tggctgcccc tacatctaca agagaggtaa
3481 tgactatgtg gtcattggag tccacacggc tgccgcacga gggggaaaca ccgtcatatg
3541 tgccacccag gggagtgaag gagaggccac gcttgaaggt ggtgacaaca agggcacata
3601 ctgtggtgca ccaatcttag gcccagggaa tgctccaaca ctcagcacta agaccaaatt
3661 ctggagatca tccacagcat cgctgccacc tggcacatat gaaccagcct accttggtgg
3721 caaagacccc agagtcaagg gtggcccttc attgcagcaa gtcatgagag aacaattgaa
3781 accatttaca gagccaagag gcaagccacc aaaaccaagt gtattagaag ctgccaagaa
3841 gaccatcatc aatgtccttg aacaaacaat tgacccacct gagaaatggt cgttcgcaca
3901 agcctgtgcg tcccttgaca agaccacctc cagtggtcac ccgcatcatg tgcggaaaaa
3961 cgactactgg aacggggagt ccttcacagg taaattagca gaccaagctt ccaaggccaa
4021 tctaatgttt gaagaaggga agaacatgac cccagtctat acagctgcac tcaaagatga
4081 attggttaaa actgacaaaa tctatggcaa gatcaagaag aggctgctct ggggttcgga
4141 cctggcaacc atggtccgat gtgctcgagc attcgggggc ttaatggatg aactcaaggc
4201 acactgtatc acgctccctg tcagagttgg tatgaacatg aacgaggatg gccccatcat
4261 cttcgagaaa cattccaggt acgcatacca ctatgatgct gattactccc gatgggactc
4321 aacacaacag agagccgtgt tggcagcagc tctagaaatc atggtcaaat tctcctcaga
4381 accacatctg gctcaagtag ttgcagagga tctcctttct cctagtgtag tggacgtggg
4441 cgatttcaca atatcaatca acgagggtct tccctctggg gtgccttgca cctcccaatg
4501 gaattccatc gcccactggc tgctcactct ctgtgcactc tctgaagtca caaacctgtc
4561 ccctgacacc atacaggcca actccctctt ctctttctat ggtgatgatg aaattgtcag
4621 cacagacata aaattggatc cagagaaatt gacagcaaaa ctcagagagt atgggttaaa
4681 accaacccgc cctgacaaaa ctgaaggacc ccttgtcgtt tctgaagacc tgaatggcct
4741 gacattcctg cggagaactg tgacccgcga cccagctggt tggtttggaa aactggaaca
4801 aagttcaata ctcaggcaaa tgtactggac taggggcccc aaccatggag acccatctga
4861 aacaatgatc ccacactccc aaaggcccat acaattgatg tccctactgg gggaggccgc
4921 tcttcacggc ccagcctttt acagcaaaat cagtaaattg gtcattgcag agctaaaaga
4981 aggtggcatg gatttttacg tgcccagaca agaaccaatg ttcagatgga tgagattctc
5041 agatctgagc acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg
5101 cgtcgagtga cgccagccca tctaatgggt ccgcagccaa cctcgtccca gaggtcaaca
5161 atgaggttat ggctttggag cccgtagttg gtgccgctat tgcggcaccc gttgcgggcc
5221 aacaaaatgt aattgacccc tggattagaa ataattttgt acaagcccct ggtggagaat
5281 tcacagtgtc ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg
5341 acctgaatcc ctatctttcc catttggcca gaatgtacaa tggttatgca ggtggttttg
5401 aagtgcaggt aatcctcgca gggaacgcgt tcaccgcagg gaagatcata tttgcagcag
5461 tcccaccaaa tttcccaact gaaggcttga gccccagcca agtcactatg tttccccata
5521 taatagtaga tgttaggcaa ttggaacccg tgttgatccc cttacccgat gttaggaaca
5581 atttctacca ctataaccaa tcaaatgatt ctaccattaa attgatagca atgttgtata
5641 caccacttag ggctaacaat gccggggacg acgtcttcac agtctcttgc cgggttctca
5701 cgagaccgtc ccccgatttt gatttcatct ttctagtgcc gcccacagtt gaatcaagaa
5761 ctaagccatt ctctgtccca gtcttaaccg ttgaggagat gactaattca aggttcccca
5821 ttcctctgga aaagctgtac acaggtccca gcagtgcctt tgttgttcaa ccacaaaatg
5881 gcaggtgcac gactgatggc gtgctcctag gtacaaccca actgtcccct gtcaacatct
5941 gcaccttcag ggggagtgtc acccacattt caggtagccg caattggaca atgaatttgg
6001 cctcccaaaa ttggaacaat tatgatccaa cagaagaaat cccagcccct ttaggaactc
6061 cagatttcgt ggggaaaatt caaggtgtgc tcacccaaac cacaaggtca gatggttcaa
6121 cccgtggtca cactgccaca gtgctcactg ggagcgccga cttttctcca aaactgggta
6181 gagttcaatt tgccactgac acagataatg actttgaaac taaccaaaac acaaagttca
6241 ccccagttgg cgtcatccag gacggtagca ccacccaccg aaatgaaccc caacaatggg
6301 tactcccaag ttattcaggc agaggcacta acaatgtaca tcttgccccc gctgtggccc
6361 ccaccttccc gggcgagcag ctcctcttct tcaggtctac cttgcccgga tgcagcgggt
6421 accccaactt ggatttggac tgcctactcc cccaagaatg ggtgcagtac ttctaccagg
6481 aggcagctcc agcacaatct gatgtggctt tgttgagatt tgtgaatcca gatacaggta
6541 gggttttgtt tgagtgtaag ctccataaat caggctacgt cacagtggct cacactggcc
6601 aacatgattt ggttatcccc cccaatggtt actttagatt tgattcctgg gtcaaccagt
6661 tctacacact tgcccccatg ggaaatggaa cggggcgtag acgtgcatta taatggctgg
6721 agctctcttt gctggaatgg catctgatgt ccttggctcc ggactcagtt ccctaatcaa
6781 tgctggagca ggagccatca accaaaagat tgattttgac aacaacagaa aattacaaga
6841 agcctccttc caatttagta gcaatttaca acaagcctcc ttcaaacatg atcaggacat
6901 gctccaagca caaattgagg ccaccaaaaa gttgcaacag gaaatgatga gagttaaaca
6961 atcaatgctc ctagagggtg gattttctga gacagatgcg gcccgtgggg caatcaacgc
7021 ccccatgaca aaggtcttgg actggagcgg aacaagatac tgggcccctg aagctaggac
7081 tacaacatac aatgcaggcc gcttttccac cccccaatcc tcgggggcac caccagggag
7141 agctaatctt agggctgcca cccccgctcg gggttcttct tctaatactc cttctatctc
7201 ttctactgct acttctgtgt attcaaatca aaccacatca acgagacttg gttctacagc
7261 tggttctggg accagtgtct cgagtcttcc gtcaactgca aggactagga gttgggttga
7321 ggatcaaaac aggaatttat cacctttcat gagaggggcc cacaacatct cgtttgtcac
7381 cccaccatca agcagatcct ctagccaagg cacagtctca accgtgccta aagaaatttt
7441 ggactcctgg actagtgctt tcaacacgca caggcagcct ctcttcgctc atattcgtaa
7501 gcgaggggag tcacgggtgt aatgtgaaaa gacttaattg attatctttc ctatctttac
7561 tgtcttttaa aaa
//