Typing tool
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Typing tool
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Complete norovirus genomes
| PV266775 | GII.4 Wichita | |
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| GII.P4 New Orleans |
ORF1: 1..5098
ORF2: 5079..6701
ORF3: 6701..7510
LOCUS PV266775 7561 bp RNA linear VRL 17-MAR-2025
DEFINITION Norovirus GII isolate Hu/GII.4 Wichita[P4]/Houston3034/2023/USA
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION PV266775
VERSION PV266775.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7561)
AUTHORS Chhabra,P., Montmayeur,A.M., Bartlett,E., Boom,J. and Vinje,J.
TITLE Direct Submission
JOURNAL Submitted (12-MAR-2025) Division of viral diseases, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: 454; Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7561
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/GII.4 Wichita[P4]/Houston3034/2023/USA"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="USA"
/collection_date="22-Dec-2023"
/note="genotype: GII.4 Wichita[P4]"
gene <1..5098
/gene="ORF1"
CDS <1..5098
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="XPT11014.1"
/translation="ASAAAVANSNNDIAKSSSDGVLSSMAVTFKRALGAKPKQPPPRE
KQQQQQQQQKPPRPSTPELVKRIPPPPPNGEDEVVVSYSVKDGVSGLPDLTTVRQPEE
SNTAFSVPPLNLRENKDAKEPLTGTILEMWDGEIYHYGLYVDRGLVLGVHKPPAAISL
AKVELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDSW
LNRRMIQRTTGFFRPYQDWNRKPLPTMDDSKMKKVANIFLCALSSLFTRPIKDIIGKI
RPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAIIAPLLGDYELQGPEDI
AVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPK
KEEKNELAMVRAIEDAVLDLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARKLSTK
SASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREVA
KRIASSLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCP
LTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKA
KRDFPGQPDMWKNAFSSDFSHIKLTLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARAS
GLLHERLDEFELQGPALTTFNFDRNKVLTFRQLAAENKYGLMDTMRVGKQLKDVKTMS
ELRQALKNVSIKKCQIVYSGNTYILESDGKGNVKVDKVQSAAVQVNNELAGALHHLRS
ARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQLEDTEETASKDGCP
KPKDDEEFVVSSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGK
YSIEEYLQDRDKYYEELAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVT
GSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPS
LFITSTHVIPHGVKEFFGVPIKQIQIHKSGEFCRLRFPRPIRTDVTGMILEEGAPEGT
VASLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDC
GCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGP
GNAPTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEPR
GKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPYHVRKNDYWN
GESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLA
TMVRCARAFGGLMDELKAHCITLPVRVGMNMNEDGPIIFEKHSRYAYHYDADYSRWDS
TQQRAVLAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCTS
QWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLRE
YGLKPTRPDKTEGPLVVSEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPN
HGDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEP
MFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..988
/gene="ORF1"
/product="p48"
mat_peptide 989..2086
/gene="ORF1"
/product="NTPase"
mat_peptide 2087..2623
/gene="ORF1"
/product="p22"
mat_peptide 2624..3022
/gene="ORF1"
/product="VPg"
mat_peptide 3023..3565
/gene="ORF1"
/product="Pro"
mat_peptide 3566..5095
/gene="ORF1"
/product="RdRp"
gene 5079..6701
/gene="ORF2"
CDS 5079..6701
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="XPT11015.1"
/translation="MKMASSDASPSNGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLYTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGSVTHISGSRNWTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRSNGSTRGHTATVLTGSADFSPKLGRVQFATDTDNDFETNQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRGTNNVHLAPAVAPTFPGEQLLFFRSTLPGCSGYPNLDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6701..7510
/gene="ORF3"
CDS 6701..7510
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="XPT11016.1"
/translation="MAGALFAGMASDVLGSGLSSLINAGAGAINQKIDFDNNRKLQEA
SFQFSSNLQQASFKHDQDMLQAQIEATKKLQQEMMRVKQSMLLEGGFSETDAARGAIN
APMTKVLDWSGTRYWAPEARTTTYNAGRFSTPQSSGAPSGRANLRAATPARGSSSNTP
SISSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHN
ISFVTPPSSRSSSQGTVSTVPKEILDSWTSAFNTHRQPLFAHIRKRGESRV"
ORIGIN
1 cgcttccgct gccgctgttg ctaacagcaa caacgacatc gcaaaatctt caagtgacgg
61 agtgctttct agcatggctg tcacttttaa acgagccctc ggggcgaagc ctaaacagcc
121 tcccccgagg gaaaaacaac aacaacaaca acaacaacaa aaacccccac gaccatccac
181 tccagaactg gtcaaacgta ttccccctcc cccacccaac ggggaggatg aagtggtggt
241 ctcttacagt gttaaagatg gtgtttctgg cctgcctgac cttaccaccg ttaggcagcc
301 agaagaatct aacacggcct ttagcgtccc tccactcaac ctaagggaga acaaagatgc
361 caaggagcca cttactggaa caattctgga aatgtgggac ggggaaattt accactatgg
421 cctgtatgtg gaccgaggtc tcgtactagg tgtacacaaa ccaccagctg ccattagcct
481 cgccaaggtt gagctagcac cactctcctt gtactggaga cctgtgtaca ctcctcagta
541 cctcatctca ccggacactc tcaagaagct gtccggagag actttcccct acacagcctt
601 tgacaacaac tgttatgcct tttgctgctg ggtcctggac ctaaatgact catggctgaa
661 caggagaatg atccagagaa caaccggttt cttcagaccc taccaagact ggaataggaa
721 accccttccc accatggatg actccaaaat gaagaaggta gctaacattt tcctgtgtgc
781 tctgtcctca ctgttcacca gacccataaa ggacataata gggaagataa ggccactcaa
841 catcctcaac atcctggcct catgtgattg gacttttgca ggcatagtag aatccctgat
901 actcttggca gaactctttg gagtcttctg gacaccccca gatgtgtctg cgataattgc
961 ccccttactc ggtgattacg agctgcaagg acctgaagac attgcagtag agcttgtccc
1021 cgtggtgatg ggggggattg gtttggtgct gggattcacc aaagagaaga ttgggaaaat
1081 gttatcatct gctgcatcca cattaagagc ttgtaaagac cttggtgcat atgggctgga
1141 gatcctaaag ctggttatga agtggttctt cccgaagaag gaggagaaaa atgagctggc
1201 tatggtgagg gctatcgagg atgcagtcct ggacctcgag gcaattgaaa acaaccattt
1261 gaccaccttg cttaaggaca aagacagtct ggcaacctat atgaggaccc ttgaccttga
1321 ggaggagaaa gccaggaaac tctcaaccaa gtctgcttca cctgacatcg tgggcacaat
1381 caacgccctc ctggcgagaa tcgccgccgc acgctctctg gtacaccgag cgaaggagga
1441 gctctccagc agaccaagac ctgtggtgtt gatgatctca ggcaggccgg gaataggaaa
1501 gacccatctc gccagggaag tggctaagag aatcgcatcc tccctcacag gggaccagcg
1561 tgtgggcctc attccacgca acggcgtcga ccactgggat gcgtacaaag gggagagggt
1621 cgtcctatgg gacgactatg gaatgagcaa ccctattcac gacgccctca ggttgcaaga
1681 actcgccgac acctgtcccc tcaccctaaa ttgtgacagg attgaaaaca aagggaaagt
1741 ctttgacagc gatgtcatca ttatcaccac caacctggcc aacccagcac cactggacta
1801 tgtcaacttt gaagcatgct cgaggcgcat cgacttcctc gtgtatgcag aagcccctga
1861 ggttgaaaag gcgaagcgtg acttcccagg ccagcctgac atgtggaaga acgctttcag
1921 ttctgatttc tcacacataa agttaacatt ggccccacag ggtggttttg acaaaaacgg
1981 gaacacccca cacggaaagg gcgtcatgaa gactctcacc actggttccc tcattgcccg
2041 ggcatcaggg ttactccatg agagattaga cgaatttgaa ctacagggcc cagctctcac
2101 caccttcaat ttcgatcgca ataaggtgct taccttcaga cagcttgctg cagaaaacaa
2161 atatggactg atggacacaa tgagggtcgg gaaacaactc aaggatgtca aaaccatgtc
2221 agaactcaga caagcactca agaatgtctc aatcaagaag tgccaaatag tgtatagtgg
2281 taacacctac atacttgagt ctgatggcaa gggcaacgtg aaagttgaca aagttcaaag
2341 cgccgctgtg caggtcaaca atgagctggc cggcgccctg catcacttga ggagcgccag
2401 aatcaggtac tatgtcaagt gtgtccagga ggccctgtat tccatcattc aaattgctgg
2461 agctgcattc gtcaccacgc gcattgccaa acgcatgaac atacaaaacc tatggtctaa
2521 accacaattg gaagacacag aggaaactgc cagcaaggac gggtgcccaa aacccaagga
2581 tgatgaggag tttgtcgttt catccgacga catcaaaact gagggcaaga aggggaagaa
2641 taagactggc cgtggcaaga aacacacagc attttcaagc aaaggcctca gtgatgaaga
2701 gtacgatgag tacaagagga tcagggaaga aaggaacggc aagtactcca tagaagagta
2761 ccttcaggac agggacaaat actatgaaga attggccatt gccagggcga ctgaggaaga
2821 cttctgcgaa gaagaggagg ccaagatccg gcaaaggatc ttcaggccaa caaggaaaca
2881 acgcaaggag gaaagagctt ctctcggcct ggtcacaggc tctgaaatta gaaagaggaa
2941 cccagaagac ttcaagccca agggaaaact gtgggctgac gatgacagga gtgtggacta
3001 caatgaaaag ctcagctttg aggccccgcc aagcatctgg tcaagaatag tcaattttgg
3061 ttcaggttgg ggattctggg tctcccctag tctgtttata acatcaaccc atgtcatacc
3121 ccatggtgta aaagaattct ttggagtccc catcaaacaa atacagatac acaaatcagg
3181 cgagttctgt cgcttgaggt tcccaagacc aatcaggact gatgtgacgg gcatgatctt
3241 agaagaagga gcacctgagg gcaccgtggc ctcattactc atcaaaagac ccactgggga
3301 actcatgccc ctagcagcta ggatggggac ccacgccacc atgaagattc aagggcgcac
3361 cgttggaggc cagatgggca tgctactaac aggatccaac gccaagagca tggacctggg
3421 taccacacca ggtgattgtg gctgccccta catctacaag agaggtaatg actatgtggt
3481 cattggagtc cacacggctg ccgcacgagg gggaaacacc gtcatatgtg ccacccaggg
3541 gagtgaagga gaggccacgc ttgaaggtgg tgacaacaag ggcacatact gtggtgcacc
3601 aatcttaggc ccagggaatg ctccaacact cagcactaag accaaattct ggagatcatc
3661 cacagcatcg ctgccacctg gcacatatga accagcctac cttggtggca aagaccccag
3721 agtcaagggt ggcccttcat tgcagcaagt catgagagaa caattgaaac catttacaga
3781 gccaagaggc aagccaccaa aaccaagtgt attagaagct gccaagaaga ccatcatcaa
3841 tgtccttgaa caaacaattg acccacctga gaaatggtcg ttcgcacaag cctgtgcgtc
3901 ccttgacaag accacctcca gtggtcatcc gtatcatgtg cggaaaaacg actactggaa
3961 cggggagtcc ttcacaggta aattagcaga ccaagcttcc aaggccaatc taatgtttga
4021 agaagggaag aacatgaccc cagtctatac agctgcactc aaagatgaat tggttaaaac
4081 tgacaaaatc tatggcaaga tcaagaagag gctgctctgg ggttcggacc tggcaaccat
4141 ggtccgatgt gctcgagcat tcgggggctt aatggatgaa ctcaaggcac actgtatcac
4201 gctccctgtc agagttggta tgaacatgaa cgaggatggc cccatcatct tcgagaaaca
4261 ttccaggtac gcataccact atgatgctga ttactcccga tgggactcaa cacaacagag
4321 agccgtgttg gcagcagctc tagaaatcat ggtcaaattc tcctcagaac cacatctggc
4381 tcaagtagtt gcagaggatc tcctttctcc tagtgtagtg gacgtaggcg atttcacaat
4441 atcaatcaat gagggtcttc cctctggggt gccctgcacc tcccaatgga attccatcgc
4501 ccactggctg ctcactctct gtgcactctc tgaagtcaca aacctgtccc ctgacaccat
4561 acaggccaac tccctcttct ctttctatgg tgatgatgaa attgtcagca cagacataaa
4621 attggaccca gagaaattga cagcaaaact cagagagtat gggttaaaac caacccgccc
4681 tgataaaact gaaggacccc ttgtcgtttc tgaagacctg aatggcctga cattcctgcg
4741 gagaactgtg acccgcgacc cagctggttg gtttggaaaa ctggaacaaa gttcaatact
4801 caggcaaatg tactggacta ggggccccaa ccatggagac ccatctgaaa caatgattcc
4861 acactcccaa aggcccatac aattgatgtc cctactgggg gaggccgctc ttcacggccc
4921 agccttttac agcaaaatca gtaaattggt cattgcagag ttaaaagaag gtggcatgga
4981 tttttacgtg cccagacaag aaccaatgtt cagatggatg agattctcag atctgagcac
5041 gtgggagggc gatcgcaatc tggctcccaa ttttgtgaat gaagatggcg tcgagtgacg
5101 ccagcccatc taatgggtct gcagccaacc tcgtcccaga ggtcaacaat gaggttatgg
5161 ctttggagcc cgtagttggt gccgctattg cggcacccgt tgcgggccaa caaaatgtaa
5221 ttgacccctg gattagaaat aattttgtac aagcccctgg tggagaattt acagtgtccc
5281 ctagaaacgc tccaggtgaa atactatgga gcgcgccctt aggccctgac ctgaatccct
5341 atctttccca tttggccaga atgtacaatg gttatgcagg tggttttgaa gtgcaggtaa
5401 tcctcgcagg gaatgcgttc accgcaggga agatcatatt tgcagcagtc ccaccaaatt
5461 ttccaactga aggcttgagc cccagccaag tcactatgtt tccccatata atagtagatg
5521 ttaggcaatt ggaacccgtg ttgatcccct tacccgatgt taggaataat ttctaccact
5581 ataaccaatc aaatgactct accattaaat tgatagcaat gttgtataca ccacttaggg
5641 ctaacaatgc cggggacgac gtcttcacag tctcttgccg ggttctcacg agaccgtccc
5701 ccgattttga tttcatcttt ctagtgccgc ccacagttga atcaagaact aagccattct
5761 ctgtcccagt cttaaccgtt gaggagatga ctaattcaag gttccccatt cctctggaaa
5821 agctgtacac aggtcccagc agtgcctttg ttgttcaacc acaaaatggc aggtgcacga
5881 ctgatggcgt gctcctaggt acaacccaac tgtcccctgt caacatctgc accttcaggg
5941 ggagtgtcac ccacatctca ggtagccgca attggacaat gaatttggcc tcccaaaatt
6001 ggaacaatta tgatccaaca gaagaaatcc cagccccttt aggaactcca gatttcgtgg
6061 ggaaaattca aggtgtgctc acccaaacca caaggtcaaa tggttcaacc cgtggtcaca
6121 ctgccacagt gctcactggg agcgccgact tttctccaaa actgggtaga gttcaatttg
6181 ccactgacac agataatgac tttgaaacta accaaaacac aaagttcacc ccagttggcg
6241 tcatccagga cggtagcacc acccaccgaa atgaacccca acaatgggta ctcccaagtt
6301 attcaggcag aggcactaac aatgtacatc ttgcccccgc tgtggccccc accttcccgg
6361 gcgagcagct cctcttcttc aggtctacct tgcccggatg cagcgggtac cccaacttgg
6421 atttggactg cctactcccc caagaatggg tgcagtactt ctaccaggag gcagctccag
6481 cacaatctga tgtggctttg ttaagatttg tgaatccaga tacaggtagg gttttgtttg
6541 agtgtaagct ccataaatca ggctacgtca cagtggctca cactggccaa catgatttgg
6601 ttatcccccc caatggttac tttagatttg attcctgggt caaccagttc tacacacttg
6661 cccccatggg aaatggaacg gggcgtagac gtgcattata atggctggag ctctctttgc
6721 tggaatggca tctgatgtcc ttggctccgg actcagttcc ctaatcaatg ctggagcagg
6781 agccatcaac caaaagattg attttgacaa caacagaaaa ttacaagaag cctccttcca
6841 atttagtagc aatttacaac aagcctcctt caaacatgat caggacatgc tccaagcaca
6901 aattgaggcc accaaaaagt tgcaacagga aatgatgaga gttaaacaat caatgctcct
6961 agagggtgga ttttctgaga cagatgcggc ccgtggggca atcaacgccc ccatgacaaa
7021 ggtcttggac tggagcggaa caagatattg ggcccctgaa gctaggacta caacatacaa
7081 tgcaggccgc ttttccaccc cccaatcctc aggggcacca tcagggagag ctaatcttag
7141 ggctgccacc cccgctcggg gttcttcttc taatactcct tctatctctt ctactgctac
7201 ttctgtgtat tcaaatcaaa ccacatcaac gagacttggt tctacagctg gttctgggac
7261 cagtgtctcg agcctcccgt caactgcaag gactaggagt tgggttgagg atcaaaacag
7321 gaatttgtca cctttcatga gaggggccca caacatctcg tttgtcaccc caccatcaag
7381 cagatcctct agccaaggca cagtctcaac cgtgcctaaa gaaattttgg actcctggac
7441 tagtgctttc aacacgcaca ggcagcctct cttcgctcat attcgtaagc gaggggagtc
7501 acgggtgtaa tgtgaaaaga cttaattgat tatctttcct atctttactg tcttttaaaa
7561 a
//